• 제목/요약/키워드: efficacy rate

검색결과 1,820건 처리시간 0.039초

뉴캣슬병 $B_1$ 생독백신의 효능비교 (Comparison of Efficacy of Newcastle Disease Virus $B_1$ Vaccine by Different Administration Method in Commerical Layer Chickens)

  • 정만호;강춘원;노용기;박진열
    • 한국동물위생학회지
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    • 제13권1호
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    • pp.96-102
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    • 1990
  • The immune responses of commercial layer chickens against Newcastle disease(ND) were compared among different administration methods and times of vaccination during 4 weeks of age. A total of 372 day-old chickens were divided into 4 groups of 93 birds each. Each of 3 groups was received a commercially available B$_1$live vaccine via drinking water, eye instillation or spray method at one, 14 and 28 days of age. One group was used as an unvaccinated control. At two and 4 weeks after each time of vaccination, 15 birds from each group were collected randomly out and challenged with virulent ND virus at the dose of $10^5E1D_{50}$ per bird. Ten to 15 birds from each group were bled at two weeks intervals from day old to 8 weeks of age for hemagglutination inhibition antibody titer, The protection rate was generally low regardless of the times of vaccination although two or more times vaccination gave higher protection than once vaccination. The low protection was considered due to low titer of the vaccine used since the vaccine titer was less than $10^{3.5}EID_{50}$ per bird. Spray method gave better protection compared to eye instillation or drinking water method which resulted in lowest response. Majority of birds showed clinical signs of ND between 3 and 6 days after challenge. Death occured one or two days after onset of symptoms. Major clinical signs observed were depression(94%), anorexia(84%), diarrhoea(29%), difficult breath(15%) and torticollis(10%). Hemorrhagic lesions on post mortem were seen in duodenum(51%), trachea(35%), illeum(13%), ceacal tonsil(11%), proventriculus(10%) and some other odrgans.

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2006년 인천의 한 유치원에서 발생한 홍역 유행 역학조사 (Epidemiological Investigation of a Measles Outbreak in a Preschool in Incheon, Korea, 2006)

  • 소재성;고운영;이동한;박광숙;이종구
    • Journal of Preventive Medicine and Public Health
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    • 제41권3호
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    • pp.153-158
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    • 2008
  • Objectives : This study describes a plan that was designed to prevent a measles outbreak that showed a changed outbreak pattern. This study is based on the epidemiological investigation of a measles outbreak in a preschool in Incheon, Korea, 2006. Methods : The subjects were 152 students at a preschool where a measles outbreak occurred. A questionnaire survey was conducted and serological testing for measles-specific IgM was preformed. Results : Of the fifteen confirmed, identified cases, eleven patients had been vaccinated with one dose, one patient had received two doses and three patients were unvaccinated. The three unvaccinated cases consisted of one 5-year-old child, one 3-year-old child and one 16-month-old infant. For the cases with one dose of the vaccination, there were 11 cases, which consisted of six 5-year-old children, two 4-year-old children, two 3-year-old children and one 2-year-old child. The case with two doses of the vaccination was one 4-year-old child. The attack rate of measles was 100% in the 0-dose group, 11.2% in the 1-dose group and 2.0% in the 2-dose group. The vaccine's efficacy was 88.8% in the 1-dose group and 98.0% in the 2-dose group. The vaccine effectiveness for the 2-dose group was higher than that of the 1-dose group. Conclusions : High coverage with a 2-dose vaccination should be maintained, and the vaccination should be given at the suitable time to prevent a measles outbreak with a changed outbreak pattern.

Immediate Debridement and Reconstruction with a Pectoralis Major Muscle Flap for Poststernotomy Mediastinitis

  • Jang, Yu-Jin;Park, Myong-Chul;Park, Dong-Ha;Lim, Hyo-Seob;Kim, Joo-Hyoung;Lee, Il-Jae
    • Archives of Plastic Surgery
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    • 제39권1호
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    • pp.36-41
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    • 2012
  • Background : Poststernotomy mediastinitis is a rare, but life-threatening complication, thus early diagnosis and proper management is essential for poststernotomy mediastinitis. The main treatment for mediastinitis is aggressive debridement. Several options exist for reconstruction of defects after debridement. The efficacy of immediate debridement and reconstruction with a pectoralis major muscle flap designed for the defect immediately after the diagnosis of poststernotomy mediastinitis is demonstrated. Methods : Between September 2009 and June 2011, 6 patients were referred to the Department of Plastic and Reconstructive Surgery and the Department of Thoracic and Cardiovascular Surgery of Ajou University Hospital for poststernotomy mediastinitis. All of the patients underwent extensive debridement and reconstruction with pectoralis major muscle flaps, advanced based on the pedicle of the thoracoacromial artery as soon as possible following diagnosis. A retrospective review of the 6 cases was performed to evaluate infection control, postoperative morbidity, and mortality. Results : All patients had complete wound closures and reduced severity of infections based on the erythrocyte sedimentation rate and C-reactive protein levels and a reduction in poststernal fluid collection on computed tomography an average of 6 days postoperatively. A lack of growth of organisms in the wound culture was demonstrated after 3 weeks. There were no major wound morbidities, such as hematomas, but one minor complication required a skin graft caused by skin flap necrosis. No patient expired after definitive surgery. Conclusions : Immediate debridement and reconstruction using a pectoralis major muscle flap is a safe technique for managing infections associated with poststernotomy mediastinitis, and is associated with minimal morbidity and mortality.

스위스에서의 국민투표에 의한 보완의학 건강보험 급여화 사례 연구 (A case study on benefit coverage of complementary medicine in public health insurance by the referendum in Switzerland)

  • 김동수;임병묵;박인효;이윤재
    • 대한예방한의학회지
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    • 제21권3호
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    • pp.29-42
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    • 2017
  • Background : Efforts towards increasing insurance coverage for traditional Korean medicine (TKM) are being continued. However, various difficulties are faced in generating evidence for TKM due to limited financial support and the low quality of research methodology. Objectives : The objectives of this study were to review the Swiss evaluation program for complementary and alternative medicine (CAM) and assess the expansion in public health insurance coverage of complementary medicine as approved by referendum in Switzerland. Methods : The regulations of CAM in the European Union were assessed. Research articles, reports, government publications and websites which deal with the 'Programm Evaluation $Komplement{\ddot{a}}rmedizin$ (PEK)' and the referendum in Switzerland were searched for and analyzed. Results : The PEK was conducted from 1998 to 2005. The PEK evaluated the efficacy, utilization and cost-effectiveness of anthroposophical medicine, homeopathy, neural therapy, phytotherapy and traditional Chinese medicine. However, clear conclusions could not be drawn from the evaluation according to the PEK Report. Later, a referendum was implemented in which 5 therapies would be added to the Switzerland Constitution with the support of the public. The coverage of CAM was approved by Swiss a plebiscite with an approval rate of 67.0%. Conclusions : The reason for the successful referendum is suggested to be public support and the solidarity with CAM experts and politicians. It may be surmised that recognition of the political efforts and scientific aspects required to expand insurance coverage of TKM, and towards obtaining public support, is necessary.

중.고등학교 운동선수들의 자살생각에 영향을 주는 관련요인 (Factors affecting suicidal ideation of athletes in middle and high school)

  • 문재우;박재산
    • 한국학교ㆍ지역보건교육학회지
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    • 제12권1호
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    • pp.1-20
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    • 2011
  • Purpose: The purpose of this study is to analyze factors affecting suicidal ideation of athletes in middle and high school. Methods: The data in this study came from the survey which conducted to 500 students of physical education high school athletes and elite athletes in general school from the beginning of December 2009 to the end of January 2010 in Seoul and Kyunggi. Finally 436 cases was used. The dependant variable is suicidal ideation in this study. And the independent variables are socio-demographic factors, exercise-related factors, school and family environments, stress and depression factor. The analysis method is logistic regression analysis. Finally 436 cases was used. Results: First, the rate of suicidal ideation of athletes in middle and high school was 28.9%. Second, there were significant differences between stress and sex, grades, athletic career, kind of sport, sport skill level, the average exercise time per day, family circumstances, life satisfaction, future expectations. Third, there were significant differences between depression and sex, academic achievements, the average exercise time per day, family circumstances, life satisfaction, future expectations. Fourth, there were significant differences between suicidal ideation and sport skill level, academic achievements, the average exercise time per day, family circumstances, life satisfaction, future expectations. Fifth, the higher level of stress and degree of depression, the more increased the risk of suicidal ideation. Conclusions: Considering the close relationship between suicidal ideation and suicidal attempt, to reduce the suicidal ideation of athletes in middle and high school it is necessary to adjust exercising time properly and to promote life satisfaction. Also to overcome depression and stress support system should be established and to promote self-efficacy cognition strength program should be introduced in the school. So athletes in middle and high school should have confidence and self-confidence on the future.

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Clinical Efficacy of Endovascular Abdominal Aortic Aneurysm Repair

  • Son, Bong-Su;Chung, Sung-Woon;Lee, Chung-Won;Ahn, Hyo-Yeong;Kim, Sang-Pil;Kim, Chang-Won
    • Journal of Chest Surgery
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    • 제44권2호
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    • pp.142-147
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    • 2011
  • Background: Endovascular aortic aneurysm repair (EVAR) has come into use and been widely extended because of the low complication rate and less-invasiveness. This article aimed to describe our experience in the treatment of abdominal aortic aneurysm with EVAR. Materials and Methods: A retrospective review was conducted for the 22 patients who underwent EVAR in a single hospital December 2001 to June 2009. Results: The mean age of the patients was $68.5{\pm}7.6$ years. There were several risk factors and comorbidities in 20 patients (90.9%). The mean diameter of the aortic aneurysms was $61.2{\pm}12.9$ mm. The mean length, diameter, and angle of the aneurysmal neck were $30.5{\pm}15.5$ mm, $24.0{\pm}4.5$ mm, and $43.9{\pm}16.0^{\circ}$, respectively. The mean follow-up period of the patients was $28.8{\pm}29.5$ months. The 30-day postoperative mortality was none. Seven patients (31.8%) had endoleaks during the hospital stay and three patients (13.6%) had endoleaks during the follow-up period. One patient (4.5%) died due to a ruptured aortic aneurysm. The cumulative patient survival rates were 88.2%, 88.2%, and 70.6% at 1, 3, and 5 years of follow-up, respectively. Conclusion: EVAR is currently a safe, feasible procedure for high risk patients with abdominal aortic aneurysm because of low postoperative complication and mortality if patients are selected properly and followed up carefully.

Comparison of Radial Artery and Saphenous Vein Composite Y Grafts during Off-pump Coronary Artery Bypass

  • Wi, Jin-Hong;Joo, Hyun-Chel;Youn, Young-Nam;Song, Suk-Won;Kim, Tae Hoon;Yoo, Kyung-Jong
    • Journal of Chest Surgery
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    • 제46권4호
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    • pp.265-273
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    • 2013
  • Background: The safety and efficacy of arterial composite grafts for total arterial revascularization have been demonstrated. The saphenous vein (SV) is a widely used graft because of its accessibility, sufficient length, and ease of manipulation. Our aim was to compare mid-term outcomes of saphenous vein Y-grafts with radial artery Y-grafts joined by anastomosis to the left internal thoracic artery. Materials and Methods: Records of off-pump coronary artery bypass grafting with composite Y-grafts based on the left internal thoracic artery technique in 552 patients were analyzed retrospectively. After propensity score matching, 79 radial arterial (RA) composite grafts (RA group) and 79 saphenous vein composite grafts (SV group) were compared. The duration of mean follow-up was $24.6{\pm}14.6$ months (range, 1 to 55 months). Results: There were no differences in surgical mortality, all-cause mortality, or morbidity among the groups. Rates of 4-year survival were 91.7% and 96.3% in the RA and SV groups, respectively (p=0.519). The coronary reintervention-free survival rate and freedom from major adverse cardiovascular or cerebrovascular events were similar in the two groups (p=0.685, p=0.564). Conclusion: Construction of composite Y-grafts using the radial artery or saphenous vein showed similar mid-term results. Long-term follow-up and randomized trials will be needed to confirm our present conclusions.

학교급식 조리종사자의 직무 만족도에 영향을 미치는 직무 소진, 직무 관여 및 조리작업안전에 대한 인식 (The Factors (Job Burnout, Job Engagement, the Workplace Safety) Influencing Employees' Job Satisfaction in School Food Service Operations)

  • 송남청;이혜상;이경은
    • 대한지역사회영양학회지
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    • 제12권5호
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    • pp.606-616
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    • 2007
  • The study was conducted to investigate the influences of food service employees' job burnout, job engagement, and workplace safety perception on their job satisfaction. A survey was administered on 589 school food service employees in Gyeongbuk from December 5, 2005 to February 18, 2006. The final response rate was 71% (N= 416); the data were analyzed using SPSS Windows (ver. 12.0). A majority of the respondents were females (99.0%) and 40 years old or older (75.3%); 84% were temporary contact-based or irregular workers. Among the job burnout dimensions, exhaustion ($2.98{\pm}0.59$) was rated higher than cynicism ($2.33{\pm}0.54$), while professional efficacy level ($3.61{\pm}0.47$) was relatively high. In terms of job engagement, the means of absorption ($3.67{\pm}0.49$) and dedication ($3.65{\pm}0.52$) were higher than that of vigor ($3.22{\pm}0.46$). A systematic environmental level ($3.15{\pm}0.58$) was lower than safety knowledge level ($3.63{\pm}0.49$) among the workplace safety statistics, whereas the anxiety level ($3.25{\pm}0.74$) was relatively high. The food service staff were more satisfied with 'supervisors' and 'co-workers' than with 'pay' and 'promotion'. A hierarchial regression analysis revealed that dedication, absorption, systematic environment, and safety knowledge were significant factors to increase job satisfaction and exhaustion which significantly decreased their job satisfaction.

Effects of Cattle Manure and Swine Slurry Acidification on Ammonia Emission as Estimated by an Acid Trap System

  • Park, Sang-Hyun;Lee, Bok-Rye;Kim, Tae-Hwan
    • 한국초지조사료학회지
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    • 제35권3호
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    • pp.212-216
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    • 2015
  • This study was conducted to assess the efficacy of slurry acidification in reducing ammonia emission from manure storage and application. The non-fermented cattle manure (NFC) and swine slurry (SS) were acidified by sulfuric acid and stored in an acryl chamber for 168 and 96 hours, respectively. Ammonia emitted from the chamber was collected using an acid trap system. The amount of ammonia emission was significantly reduced when the livestock manures were treated with sulfuric acid. The absolute amount of ammonia in NFC increased rapidly starting from 48 h and 72 h in the control (pH 8.6) and acidified NFC (pH 6.5), respectively. The absolute amount of ammonia was the highest at 96 h ($3.65g\;kg^{-1}h^{-1}$) in the control and at 144 h ($2.34g\;kg^{-1}h^{-1}$) in pH 6.5 NFC. The cumulative ammonia content in the control continuously increased until 96 h and was maintained until 168 h, whereas the increase rate of emission gas accumulation in acidified NFC was much less throughout the experimental period. Acidification of SS mitigated ammonia emission as proven in NFC. The cumulative amount of ammonia emission was decreased by 49.4% and 92.3% in the acidified SS at pH 6.5 and pH 5.5, respectively, compared to the control at 96 h after treatment. These results indicate that ammonia emission can be significantly reduced by sulfuric acid treatment of livestock manure during processing and the subsequent land application.

분화성 갑상선암 환자에서 수술범위의 선택 (The Surgical Treatment of Choice for Patients with Differentiated Thyroid Cancer(DTC))

  • 차성재;박성준;임현묵
    • 대한두경부종양학회지
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    • 제13권2호
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    • pp.200-205
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    • 1997
  • 결론적으로 저위험군환자에서는 수술방법 및 수술후 보조적인 치료법인 방사선요드동위원소 치료 및 갑상선 흐르몬 억제 치료가 생존을 증가에 별다른 영향을 주지 않으리라 생각된다. 이러한 이유는 사실상 이들 환자에서는 사망률의 위험성이 거의 없어 생존율을 확인할 방법이 없기 때문이다. 따라서 저위험군에서는 광범위한 수술방법을 피하고 고위험군에서는 환자 개개인의 상태에 따라 수술방법이 선택되어야 하며 갑상선 전절제술은 확실한 예후의 증가나 다른 적절한 치료 방법이 없을 경우 조심해서 선택되어야 된다고 사료된다.

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