• Gut and Liver
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• v.12 no.6
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• pp.623-632
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• 2018

Intestinal Behçet's disease is a rare, immune-mediated chronic intestinal inflammatory disease; therefore, clinical trials to optimize the management and treatment of patients are scarce. Moreover, intestinal Behçet's disease is difficult to treat and often requires surgery because of the failure of conventional medical treatment. Administration of anti-tumor necrosis factor-${\alpha}$, a potential therapeutic strategy, is currently under active clinical investigation, and evidence of its effectiveness for both intestinal Behçet's disease and inflammatory bowel diseases has been accumulating. Here, we review updated data on current experiences and outcomes after the administration of anti-tumor necrosis factor-${\alpha}$ for the treatment of intestinal Behçet's disease. In addition to infliximab and adalimumab, which are the most commonly used agents, we describe agents such as golimumab, etanercept, and certolizumab pegol, which have recently been shown to be effective in refractory intestinal Behçet's disease. This review also discusses safety issues associated with anti-tumor necrosis factor-${\alpha}$, including vulnerability to infections and malignancy.

• Geomechanics and Engineering
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• v.24 no.4
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• pp.399-406
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• 2021

It is a key issue in the tunnel design to evaluate the stability of the excavation face. Two efficient analytical models in the context of the limit equilibrium method (LEM) and the limit analysis method (LAM) are used to carry out the deterministic calculations of the safety factor. The safety factor obtained by these two models agrees well with that provided by the numerical modelling by FLAC 3D, but consuming less time. A simple probabilistic approach based on the Mote-Carlo Simulation technique which can quickly calculate the probability distribution of the safety factor was used to perform the probabilistic analysis on the tunnel face stability. Both the cumulative probabilistic distribution and the probability density function in terms of the safety factor were obtained. The obtained results show the effectiveness of this probabilistic approach in the tunnel design.

• Journal of the Korea Society of Computer and Information
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• v.16 no.1
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• pp.201-210
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• 2011

Each area of society has changed because of the development of information technology. Especially, the advent of NCW based on the technology of network has become a new paradigm for executing warfare. Effectiveness of NCW can be maximized by building the C4I system which is a core system of NCW. However, if we don't consider the influence in term of human dimension, we can't expect the effect of C4I system, since the key factor in C4I is human. In this paper, we propose an algorithm for evaluating Combat Power Effectiveness by considering the Influence of Human Factors that wasn't reflected in the past. Based on experimental validation our algorithm is more substantial than baseline algorithms. In addition, we proved that the Influence of Human Factors(e.g. collaboration) is the most important in battlefield. Therefore, proposed algorithm can be used for enhancing not only mission effectiveness in terms of military field but also work performance by effective Human Resource Management in terms of an enterprise.

• Health Policy and Management
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• v.15 no.3
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• pp.1-16
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• 2005

This study was planned to investigate the relationship between development levels of learning organization and organization effectiveness in Hospital. Data were collected from 285 respondents who have participated in 'Learning Organization Project'(response rate =$50.5\%$). Structured questionnaire were applied by self administrated survey for two weeks since 2003 May. Main results were as follows; In the result of factor analysis, four factor were created and almost questionnaire items were classified into as same categories as theoretical concepts. Cronbach's a coefficient also showed over 0.7 in all categories. This result means that measurement tool to evaluate the development level of learning organization is valid and reliable. In the comparison of the development level of learning organization by participants' specialties, managerial workers perceived the lowest construction level, while medical technicians evaluated it as the highest level. In regression analysis, the perception levels of work environment, task and human aspect showed positive relationship with job competency significantly. For job satisfaction, levels of task and human aspects had positive relationship significantly. In addition, for organizational commitement, levels of organization and human aspect were positive predictors. Finally, for the satisfaction about experience of learning organization project, levels of environment, task and hmm aspects were related positively. We concluded from these result that the positive relationship between construction levels of learning organization and organization effectiveness was extended to hospital, besides industrial fields. We recommend the introduction and facilitation of learning organization project in various settings to improve the competency of knowledge management in individual and organizational levels.

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 1998.06a
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• pp.725-730
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• 1998

Recently we extended the fuzzy model for rule based systems incorporating an importance factor for each rule. The model permits for both unrestricted as well as non-negative importance factors. We use this extended model to design a fuzzy rule based classifier system which uses both the firing strength of the rule and the importance factor to decide the class label. The effectiveness of the scheme is established using several data sets.

• Journal of the Korean Operations Research and Management Science Society
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• v.20 no.1
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• pp.63-81
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• 1995

This paper presents a model and algorithm for solving the multi-factor plant layout problem. The model can incorporate more than two factors that may be either quantitative or qualitative. The algorithm is based on simulated annealing, which has been successfully applied for the solution of combinatorial problems. A set of problems previously used by various authors is solved to demonstrate the effectiveness of the proposed methods. The results indicate that the proposed methods can yield good quality for each of eleven test problems.

• Proceedings of the Safety Management and Science Conference
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• 2003.11a
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• pp.75-80
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• 2003

The objectives of this study is to achieved by the use of the conceptual approach and accident data bases to develop statistical accident analysis, effectiveness values, comparison analysis of statistical models to determine which variables are significantly related to accidents, human factor, and hazard factor analysis, all of which were used in the railroad crossing. The result from this approach applicable to the railroad crossing where systematic safety management criteria have been considered.

• Proceedings of the KIPE Conference
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• 2012.07a
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• pp.224-225
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• 2012

When Power Factor Correction(PFC) boost converter is designed for the universal input range, unwanted burst operation can be found at high line and light load. This operation may cause an audible noise from the boost inductor or sensitive flicker for human eye can be found in case of the display application. In order to solve this difficulty, this paper proposes the new control range compensation method and shows the effectiveness than the conventional method thru the experimental result.

• Land and Housing Review
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• v.1 no.1
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• pp.125-134
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• 2010

Integrating corporate culture in a merger enterprise is considered as one of the most important variables to decide M&A success. This study established a conceptional model according to the preceding study on integrating corporate culture and organizational effectiveness, and formulated a hypothesis on the interrelation between a seven factors of corporate culture proposed by Pascale & Athos and Peters & Waterman and organizational effectiveness. The result of applying multi-regression analysis to test the hypothesis is as follows; firstly, all of a merger enterprise's cultural factors have meaningful influence on job involvement among organizational effectiveness; secondly, all of them have sincere influence on job satisfaction among organizational effectiveness except shared value; and thirdly, all of them except skill have significant influence on organizational harmony among organizational effectiveness. This is a significant empirical and exploratory study to ascertain the variables of corporate culture factors, and to verify their effects on organizational effectiveness.

• Journal of the Korean Society for information Management
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• v.32 no.2
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• pp.105-129
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• 2015

The purpose of this study was to explore the effects of librarian's empowerment and organizational commitment on organizational effectiveness in libraries. The subjects of this study were 148 librarians of 10 libraries in Jeollabuk-do in accordance to purposeful sampling of nonprobability sampling. The statistics program that was used to achieve the purpose was SPSS pc+ 20.0. The statistics methods were used one-way ANOVA, Pearson's correlation analysis, and multiple regression test. The following conclusion were drawn from the research procedures and data analysis. First, the librarian's empowerment level and organizational effectiveness make a difference by age level. But the librarian's organizational commitment make no difference by age level. Second, the librarian's empowerment level make a difference by marital status. But the librarian's organizational commitment and effectiveness make no difference by marital status. Third, the librarian's empowerment level make a difference by career in present librarian. But the librarian's organizational commitment and effectiveness make no difference by career in present librarian. Fourth, Very a high correlation is influence factor and all of the empowerment, competence factor, and all of the empowerment. Fifth, the organizational effectiveness is affected 9.3% by librarian's empowerment, 5.6% by librarian's organizational commitment.