• Title/Summary/Keyword: effective compound

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Studies on the Synthesis and Antibacterial Activity of 2-Ethoxymethyl-3-(5-nitro-2-furyl)acrylamide Derivatives (2-Ethoxymethyl-3-(5-nitro-2-furyl)acrylamide 유도체(誘導體)의 합성(合成) 및 항균작용(抗菌作用)에 관(關)한 연구(硏究))

  • Ko, Ok-Hyun
    • Journal of Pharmaceutical Investigation
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    • v.10 no.4
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    • pp.8-22
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    • 1980
  • In order obtain some new antibacterial agents, seven new 2-ethoxymethyl-3-(5-nitro-2-furyl) acrylamide derivatives were synthesized by condensing 2-ethoxymethyl-3-(5-nitro-2-furyl) acyloyl chloride with amino compounds namely 5-amino-3, 4-dimethyl isoxazole, sulfamonomethoxazole, d-2-amino-1-butanol, hydroxylamine hydrochloride, semicarbazide hydrochloride, thiosemicarbazide, and p, p'-diaminodiphenylsulfone, respectively. The seven synthesized compounds were 2-ethoxymethyl-3-(5-nitro-2-furyl) acryl-5-amino-3, 4-dimethylisoxazoleamide [VII], $N^4-[2-ethoxymethyl\;3-methyl\;(5-nitro-2-furyl)\;acryl]-N^1-(5-methyl-3-isoxazolyl)$ sulfanilamide [VIII], 2-ethoxyl-3-(5-nitro-2-furyl) acrylsemicarbazide [X], 2-ethoxymethyl-3-(5-nitro-2-furyl) acrylthiosemicarbazide [XI], 2-ethoxymethyl-3-(5-nitro-2-furyl) acryl-d-2-amino-1-butanolamide [XII], and 4, 4'-di[2-ethoxymethyl-3-(5-nitro-2-furyl) acryl-amido] diphenylsulfone [XIII]. These compounds, with exception of the compound XIII, showed generally effective antibacterial activity, especially in the following instances. Compound VII was shown to be effective against Bacillus subtilis ATCC 6633 compound VIII, against Bacillus cereus var. Mycoides ATCC 1778, and compound XII, against both Proteus vuglaris and Saccharomyces cerevisiae ATCC 9763.

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Validation on Conceptual Design and Performance Analyses for Compound Rotorcrafts Considering Lift-offset

  • Go, Jeong-In;Park, Jae-Sang;Choi, Jong-Soo
    • International Journal of Aeronautical and Space Sciences
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    • v.18 no.1
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    • pp.154-164
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    • 2017
  • This work conducts a validation study for the XH-59A helicopter using a rigid coaxial rotor system in order to establish the techniques of the conceptual design and performance analysis for the lift-offset compound rotorcraft. As a tool for conceptual design and performance analysis, NDARC (NASA Design and Analysis of Rotorcraft) is used for the present study. An assumed mission profile is considered for the conceptual design of the XH-59A. As a validation result of the design, the dimensions and weight of the XH-59A are appropriately designed when compared to the target values since the relative error is less than 0.5%. Then, performance analyses are conducted for the designed XH-59A model with and without auxiliary propulsion in hover and forward flight conditions. The present analyses show good validity since the prediction results compare well with both the flight test and previous analyses. Therefore, the techniques for the conceptual design and performance analysis of the lift-offset compound helicopter are overall considered to be appropriately established. In addition, this study investigates the influence of the lift-offset on the rotor effective lift-to-drag ratio of the XH-59A helicopter with auxiliary propulsion. As a result, the improvement of the rotor effective lift-to-drag ratio can be obtained by appropriately increasing the lift-offset in high-speed flight.

토양내 탄화수소계 화합물의 농도측정 기법에 대한 TDR(Time Domain Reflectometry)적용 가능성 연구

  • 박민수;김동주
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 1998.11a
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    • pp.201-205
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    • 1998
  • Leakage of hydrocarbon compound from underground storage tank has been a significant issue to the hazard of environmental contaminants. It is therefore necessary to develop the measurement technique of hydrocarbon compound concentration. In this study, the possibility of TDR application to measure concentration of hydrocarbon compound, especially diesel, in a sandy soil was investigated. Experiments were conducted in two different conditions. The first one was to measure the resistances of the soil columns packed according to the various ratios of tab water and diesel content in the total voids. The other was to measure the resistance of the soil under the flow condition where diesel oil was allowed to infiltrate into the KCl-saturated soil column. The experimental results showed that there exists a significant relationship between oil% and TDR-measured resistance. This suggests that TDR can be an effective device to measure the concentration of hydrocarbon compound in a soil.

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Compound Explosives Detection and Component Analysis via Terahertz Time-Domain Spectroscopy

  • Choi, Jindoo;Ryu, Sung Yoon;Kwon, Won Sik;Kim, Kyung-Soo;Kim, Soohyun
    • Journal of the Optical Society of Korea
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    • v.17 no.5
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    • pp.454-460
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    • 2013
  • We present qualitative and quantitative component analyses on compound explosives via Terahertz time-domain spectroscopy (THz-TDS) based on a combination of wavelet thresholding and wavelength selection. Despite its importance, the field of signal processing of THz signals of compound plastic explosives is relatively unexplored. In this paper, experiment results from explosives Composition B-3 and Pentolite are newly presented, suggesting a novel signal processing procedure for in situ compound explosives detection. The proposed signal processing method demonstrates effective component analysis even in noisy and humid environments, showing significant decrease in component concentration percentage error of approximately 22.7% for Composition B-3 and 48.8% for Pentolite.

Antipruritic Effects of Ethanol Extracts from Perillae Japonicae Semen leaves and Chaenomelis Fructus (임자잎과 모과 에탄올 추출물의 피부 가려움증 억제 효과)

  • Kim, Hyeon-Soo;Jeon, In-Hwa;Mok, Ji-Ye;Kang, Hyun-Ju;Jang, Seon-Il
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.26 no.3
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    • pp.314-319
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    • 2012
  • Itching is one of the major diagnostic criteria of atopic dermatitis (AD) and one of its most troublesome symptoms that provokes the desire to scratch. Effective control of itching is believed to be one of the basic approaches in controlling AD. The purpose of this study was undertaken to investigate the antipruritic effect of ethanol extracts from Perillae Japonicae Semen leaves (PJSL) and Chaenomelis Fructus (CF) on the scratching behavior induced by pruritogen such as compound 48/80 or substance P in hairless mice. PJSL or CF treatment inhibited histamine release in HMC-1 stimulated compound 48/80 or substance P in a dose-dependant manner. In particularly, co-treatment PJSL ($50{\mu}g/mL$) plus CF ($100{\mu}g/mL$) significantly inhibited histamine release in HMC-1 stimulated compound 48/80 or substance P. PJSL, CF or PJSL plus CF was administered orally for 2 h and then compound 48/80 ($50{\mu}g/site$) or substance P ($100{\mu}g/site$) was injected into rostral back, and scratching of the injected site by the hind paw was counted for 1 h. PJSL or CF administration reduced the scratching behavior induced by compound 48/80 as well as substance P in a dose-dependent manner. Furthermore, co-administration of PJSL and CF markedly suppressed the scratching behavior induced by compound 48/80 as well as substance P. These suppressive effects were synergistically increased by their combination. From the preliminary observations, we considered that ethanol extracts from PJSL and CF could be an effective natural materials for itching treatment.

Effective Thematic Words Extraction from a Book using Compound Noun Phrase Synthesis Method

  • Ahn, Hee-Jeong;Kim, Kee-Won;Kim, Seung-Hoon
    • Journal of the Korea Society of Computer and Information
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    • v.22 no.3
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    • pp.107-113
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    • 2017
  • Most of online bookstores are providing a user with the bibliographic book information rather than the concrete information such as thematic words and atmosphere. Especially, thematic words help a user to understand books and cast a wide net. In this paper, we propose an efficient extraction method of thematic words from book text by applying the compound noun and noun phrase synthetic method. The compound nouns represent the characteristics of a book in more detail than single nouns. The proposed method extracts the thematic word from book text by recognizing two types of noun phrases, such as a single noun and a compound noun combined with single nouns. The recognized single nouns, compound nouns, and noun phrases are calculated through TF-IDF weights and extracted as main words. In addition, this paper suggests a method to calculate the frequency of subject, object, and other roles separately, not just the sum of the frequencies of all nouns in the TF-IDF calculation method. Experiments is carried out in the field of economic management, and thematic word extraction verification is conducted through survey and book search. Thus, 9 out of the 10 experimental results used in this study indicate that the thematic word extracted by the proposed method is more effective in understanding the content. Also, it is confirmed that the thematic word extracted by the proposed method has a better book search result.

Compound effects of operating parameters on burnup credit criticality analysis in boiling water reactor spent fuel assemblies

  • Wu, Shang-Chien;Chao, Der-Sheng;Liang, Jenq-Horng
    • Nuclear Engineering and Technology
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    • v.50 no.1
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    • pp.18-24
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    • 2018
  • This study proposes a new method of analyzing the burnup credit in boiling water reactor spent fuel assemblies against various operating parameters. The operating parameters under investigation include fuel temperature, axial burnup profile, axial moderator density profile, and control blade usage. In particular, the effects of variations in one and two operating parameters on the curve of effective multiplication factor ($k_{eff}$) versus burnup (B) are, respectively, the so-called single and compound effects. All the calculations were performed using SCALE 6.1 together with the Evaluated Nuclear Data Files, part B (ENDF/B)-VII238-neutron energy group data library. Furthermore, two geometrical models were established based on the General Electric (GE)14 $10{\times}10$ boiling water reactor fuel assembly and the Generic Burnup-Credit (GBC)-68 storage cask. The results revealed that the curves of $k_{eff}$ versus B, due to single and compound effects, can be approximated using a first degree polynomial of B. However, the reactivity deviation (or changes of $k_{eff}$, ${\Delta}k$) in some compound effects was not a summation of the all ${\Delta}k$ resulting from the two associated single effects. This phenomenon is undesirable because it may to some extent affect the precise assessment of burnup credit. In this study, a general formula was thus proposed to express the curves of $k_{eff}$ versus B for both single and compound effects.

Effects of Carbon Black Morphology and Loading Level on the Physical Properties of Natural Rubber Compound (카본블랙의 형태 특성이 천연고무 배합 물성에 미치는 영향)

  • Choi, Kwan-Young;Yoon, Jae-Ryong;Kim, Hwi-Joong
    • Elastomers and Composites
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    • v.33 no.1
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    • pp.17-26
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    • 1998
  • Natural rubber was filled with 8 commercial carbon blacks covering range of rubber-grade products at different levels of filler loadings in order to investigate physical compound and vulcanizate properties. It was found that the curves of rubber property vs filler loading of both uncured compounds and vulcanizates can be superposed to one single master curve by introducing an effective volume fraction which is based on CDBP. The effective volume fraction, $V_{EFF}$ was utilized to explain the variation of the stiffness of all rubber compounds. The surface area-corrected effective volume fraction, V', was utilized to explain the formation of bound rubber, rebound and lambourn wear.

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Effect of Sodium Methyl Arsenate as a Male Gametocide on Rice (Oryza sativa L.) (수도 웅성불임제로서 Sodium Methyl Arsenate의 효과)

  • Cho, Soo-Yeon;Son, Young-Hee;Choi, Hae-Chun;Moon, Huhn-Pal;Park, Rae-Kyeong;Park, Nam-Kyu;Kim, Chong-Ho
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.34 no.1
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    • pp.55-59
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    • 1989
  • Sodium methyl arsenate has been evaluated as a male sterilizing agent for the system of producing hybrid rice seeds. The compound was the most effective at the concentration of 0.02%. When applied as a foliar spray to four rice varieties at 15 days before heading, sodium methyl arsenate has produced 99% male sterility. But the most effective time for application of the compound was 5 days before heading because of its phytotoxic effects. Effective application volume of the compound solution has depended on the growth of the plants treated. Varietal difference on the activity of the compound has been detected.

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Functional Properties of Cholesterol-removed Compound Whipping Cream by Palm Oil

  • Shim, S.Y.;Ahn, J.;Kwak, H.S.
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.6
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    • pp.857-862
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    • 2004
  • The present study was carried out to examine the changes in functional properties of cholesterol-removed compound whipping cream made by $\beta$-CD treated cream and palm oil. Six different ratios of cream to palm oil (10:0 as control, 9:1, 8:2, 7:3, 6:4, and 5:5, v/v) were tested. The overrun percentage increased with an increased amount of palm oil. When the ratio of cream to palm oil was 10:0 (control), the overrun was 130%, which was significantly lower than other ratios reached to 150%. Foam instability was measured as 3.1 ml defoamed cream in control, however, the value of foam instability decreased with an increase of palm oil addition. The TBA value of cholesterol-removed compound whipping cream increased from 0.08 to 0.13 with no addition of palm oil during 4 wk storage. When the ratio of cream to palm oil was 5:5, TBA value increased dramatically at 3 wk and thereafter. Among sensory characteristics, texture value increased with higher amount of palm oil, however, flavor and overall preferences were opposite. Above results indicated that partial substitution of palm oil in manufacture of cholesterol-removed compound whipping cream resulted in a stable foam development with little adverse effect on flavor and lipid oxidation during storage. The present study showed a possible application in manufacture of cholesterol-removed compound whipping cream, which may be effective in other foods.