• The Korean Journal of Physiology and Pharmacology
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• v.6 no.4
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• pp.225-233
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• 2002

Kanagawa hemolysin (KH), an exotoxin produced from Kanagawa phenomenon-positive Vibrio parahemolyticus, has been shown to possess various biological activities including hemolysis, enterotoxicity, cytotoxicity, and cardiotoxicity. The aim of this study was to investigate the effect of KH on the cardiovascular system and its mechanism, employing in vivo and in vitro experiments of the rat. Intracerebroventricular (icv) administration of 100 mHU KH produced a marked and continuous pressor effect (icv KH-pressor effect), and the icv pressor effect was not repeatable. However, intravenous (iv) injection of the same dose of KH induced a prominent depressor effect (iv KH-depressor effect). The icv KH-pressor effect was inhibited by acid-denaturation, while the iv KH-depressor effect was not. Simultaneous icv administration of the three agents (ouabain, diltiazem, or bumetanide: $10{\mu}g/kg$ each) significantly reduced the pressor effect. The icv KH-pressor effect was inhibited by treatment with iv phentolamine or chlorisondamine, but was not affected by iv candesartan. The iv KH-depressor effect was repeatable and was attenuated by treatment with iv NAME or methylene blue. In vitro experiments using isolated thoracic aorta, $10^{-6}$ M phenylephrine (PE) and 50 mM KCl produced a sustained contraction. In rings contracted with either agents, KH showed relaxant responses in a concentration- dependent fashion and the relaxation (KH-vasorelaxation) was not dependent on the existence of the endothelium. The KH-vasorelaxation in the endothelium-intact rings contracted by PE was abolished by methylene blue treatment. In summary, the present findings suggest that in the icv KH-pressor effect the cation leak-inducing action of KH is implicated, which leads to the increased central sympathetic tone, that the iv KH-depressor effect results from the vasorelaxation via NO-guanylate cyclase system, and that the KH-vasorelaxation is independent of the endothelium and the guanylate cyclase system is involved in it. In conclusion, the mechanism of KH producing the icv pressor effect may not be identical to that of KH producing the iv depressor effect.

• Journal of Korean Academy of Nursing
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• v.30 no.6
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• pp.1503-1520
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• 2000

The purpose of the present study is 1) to explain major effect models (main, moderating, and mediating) of social support and statistical methods for testing the effect models and 2) to analyze and evaluate the consistency in the use of the effect models and its statistical methods in Korean nursing studies. A total of 57 studies were selected from Journal of Korean Academy of Nursing, Journal of Korean Academic Society of Adult Nursing, Journal of Korean Women's Health Nursing Academic Society, Journal of Fundamentals of Nursing, Journal of Korean Community Nursing, Journal of Korean Psychiatric and Mental Health Nursing Academic Society, and Journal of Korean Pediatric Nursing Academic Society published in the year of 1990-1999. In results, most studies on social support performed in Korea Nursing Society were about a main effect model. There are few studies on moderating or mediating model of social support. Thus, it was difficult to find research findings how, why, under what conditions social support impacted on health outcomes. Most studies on the moderating or mediating effect model of social support used statistical methods for testing main effect model rather than for testing moderating or mediating effect model. That is, there are inconsistency between effect models of social support and its statistical methods in Korean nursing researches. Therefore, it is recommended to perform studies on moderating or mediating effect model and use appropriate statistical methods.

• The Journal of Korean Physical Therapy
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• v.32 no.5
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• pp.277-282
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• 2020

Purpose: The main purposes of this study are to identify the degree of effect size and variables related to it, on the effect of physical therapy on shoulder adhesive capsulitis. Methods: This study were collected 8 studies published between 2010.01.01. and 2020.08.01. The Analysis result confirmed 16 effect size data, the random effect model was chosen because of the heterogeneity of the data. Results: First, full case showed the largest mean effect size 3.28 (p<0.001). Second, Size of the effect according to hands on+off intervention the 5.17 (p>0.344). Third, Number of participants showed 15 or more effect size 4.19 (p<0.002). intervention period showed 8 weeks effect size 5.12 (p>0.425). Number of intervention showed 14 or less effect size 3.99 (p>0.061). Publication type showed thesis effect size 4.34 (p<0.003). Finally, 'Trim and Fill' result confirmed that the calibration effect size is 1.71 (p<0.001). Conclusion: We were able to confirm that physical therapy had great effect on shoulders adhesive capsulitis, and that the effect differed according to the methods of intervention, the methods of evaluation.

• THE INTERNATIONAL COMMERCE & LAW REVIEW
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• v.40
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• pp.33-63
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• 2008

This study introduces the adoption of the logistics industry by the Korean government as a threshold of overcoming economic difficulties. The core contents of the National Logistics Plans (2001-2020) which contain the basic principles of the logistics policies of the Korean government and its aim to be an 'Excellent Nation of Logistics' is introduced. The economic effect of the logistics policies implemented between 2001 and 2005, (the period of the first Medium-term Logistics Plan according to the National Logistics Plans (2001-2020) set up by the Korean government at the end of 2000) is estimated through input-output analysis. The input-output analysis result is as follows: the total output effect is 8,856 billion won of which indirect output effect is 3,982.9 billion won; indirect output effect comes mainly from real estate and business services, non-metal products, metal products, electrical and electronics products, finance and insurance, wholesale and retail, petroleum and coal; the total amount of value-added effect is 3,376 billion won and total import effect is 726 billion won. Employment effect including self-employed and unpaid family supporters with paid laborers is 79,203.7 people of which paid laborers comprise 67,547.7 people.

• Journal of Global Scholars of Marketing Science
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• v.18 no.2
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• pp.1-18
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• 2008

The objective of this paper is to describe the construct of bullwhip effect beyond supply chains, namely at industrial and societal levels. The author provides a conceptual discussion of the bullwhip effect - its derivation is extended, and the positioning of the construct is broadened. The bullwhip effect has been explored within intra-organisational and inter-organisational supply chains. A broader descriptive framework is introduced, one that positions the bullwhip effect construct at industrial and societal levels. A conceptual framework is provided that bridges the interface between the micro and macro environments of the bullwhip effect construct, but further conceptualization is required. The introduced derivation and positioning of the bullwhip effect construct reveal a number of research potentials. A principal one is that the exploration of the construct may consider the industrial and/or the societal environment when the bullwhip effect is studied in supply chains. The extended derivation and broadened positioning of the bullwhip effect in the overall environment is of interest to practitioners. It stresses the importance of contextual factors in operative, tactical and strategic supply chain performance. The principal contributions are: a) an interface between micro and macro levels in supply chain performance contributing to an extended derivation of the bullwhip effect; b) a typology of the bullwhip effect contributing to broadening the positioning of the same construct; c) the bullwhip effect being seen as two-way view construct at the micro level and d) a framework ofmanagerial implications. Most important of all is that the causes and effects of the bullwhip effect have been addressed in a wider context that so far has been underestimated in literature.

• The Journal of Korean Physical Therapy
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• v.32 no.4
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• pp.222-227
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• 2020

Purpose: The primary purposes of this study were to identify the degree of the effect size and the variables related to it on the effects of physical therapy on myofascial pain syndrome. Methods: This study collected 15 studies published between 2008.01.01 and 2019.12.31. The Analysis results confirmed 57 effect size data. The random-effect model was chosen because of the heterogeneity of the data. Results: First, the full case showed the largest mean effect size of 2.03 (p<0.001). Second, the size of the effect, according to the handson intervention, was 2.74 (p<0.003). Third, the VAS showed an effect size of 2.30 (p<0.001). Fourth, the intervention period showed a 1- to 15-day effect size of 2.94 (p<0.001). The number of interventions showed a 6 to 10 effect size of 2.84 (p<0.006). The number of participants showed a 10 or less effect size of 2.66 (p<0.001). Finally, the 'Trim and Fill' result confirmed that the calibration effect size was 0.93 (p<0.001). Conclusion: Physical therapy had a great effect on myofascial pain syndrome in the neck and shoulders, and that the effect differed according to the methods of the intervention and the methods of evaluation.

• The Journal of Information Systems
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• v.15 no.4
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• pp.23-53
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• 2006

The main purpose of this paper is to setup a integrated model and verify the integrated model for a customer loyalty in the internet shopping environments. The results of a structural equation model (SEM) using AMOS and LISREL include: First, hypothesis that Internet environment characteristics in outside factors has a positive effect on satisfaction, trust and commitment is partially supported. However, mutual communication to satisfaction, community to commitment and open-ubiquity to trust did not reveal a positive effect. Second, hypothesis that Internet showing mall environment has a positive effect on satisfaction is partially supported. However, transaction to commitment and transaction to trust did not reveal a positive effect. Third, hypothesis that relational benefits has a positive effect on both satisfaction and commitment is partially supported. However, confident honest to commitment and economic honest to trust did not reveal a positive effect. Forth, satisfaction trust and commitment have a strong effect upon loyalty. Fifth, satisfaction has a positive effect on trust and commitment. However, trust did not show a positive effect on commitment. Outside factors(Internet environment characteristics, showing mall characteristics, and relational benefit) partially revealed a positive effect on satisfaction trust, and commitment. Mediating variables such as satisfaction, trust, and commitment again have positive effect on loyalty. But, the relationship for trust to commitment did not reveal the significant effect in this study while other studies revealed significant effect.

• Journal of the East Asian Society of Dietary Life
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• v.17 no.3
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• pp.417-424
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• 2007

The purpose of this study was to measure the effects that service quality, perceived value and satisfaction have on loyalty in Namhaean area restaurants. A total of 273 questionnaires were completed. The structural equation model was used as an analysis method to measure the causal effects of service quality, perceived value, satisfaction and loyalty. The results demonstrated that the structural analysis result for the data was an excellent model fit. The effect of service quality on value, the effect of perceived sacrifice on value, the effect of service quality on satisfaction, the effect of value on satisfaction, and the effect of satisfaction on loyalty were statistically significant. Moreover service quality had an indirect effect on satisfaction through perceived value, and service quality also had an indirect effect on loyalty through perceived value and satisfaction. Perceived value had an indirect effect on loyalty, and an effect through satisfaction. Perceived sacrifice had an indirect effect on satisfaction through perceived value, and it also had an indirect effect on loyalty, and an effect through satisfaction. Further study is still required, and should be aimed at identifying the causal mechanisms of constructs, such that restaurant managers might be better prepared to offer value and satisfaction to their customers.

• Journal of Korea Trade
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• v.23 no.3
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• pp.52-67
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• 2019

Purpose - This study analyzes the effect of the authorized economic operator-mutual recognition arrangement (AEO-MRA) on the performance of Korean exporters and importers. The effect of the import-export companies' characteristics, such as annual sales, the number of foreign markets, and overseas experience, on the AEO-MRA is deduced; the relationship between this effect and firm performance is analyzed. Design/methodology - An empirical research model was constructed and analyzed using structural equation modeling. The effect of AEO-MRA on logistics and operational performance was derived from the aforementioned characteristics as leading factors of the AEO-MRA. The regulatory influence of cooperation with logistics companies was analyzed in the AEO-MRA effect on logistics performance. Thus, 172 valid samples were obtained from import-export companies certified by the AEO-MRA. Findings - Among the aforementioned characteristics, only "annual sales" has a positive effect on the AEO-MRA, whose effect enhances logistics and operational performances. The AEO-MRA effect did not directly affect operational performance. Owing to the adjustment effect analysis, the AEO-MRA effect and logistics performance relationship is strengthened if the cooperative relationship with the logistics company is higher than a certain level. If this cooperation falls below a certain level, the AEO-MRA effect on logistics performance reduces. Thus, logistics cooperation is an important factor in the AEO-MRA effect and logistics performance relationship. Originality/value - Hinging on the resource-based theory and relational viewpoint, an empirical model that explains the relationship between the AEO-MRA effect and firm performance is established.

• Journal of Korean Medical classics
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• v.30 no.4
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• pp.69-82
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• 2017

Objective : This study was conducted to infer the effect of superficies-resolveing herbs by analyzing effect terms which have extracted and refined, based on four temperatures and five tastes. Method : Firstly, temperatures, tastes and effect terms were extracted from the 27 kinds of superficies-resolving herbs written in Herbology. Then, each effect terms was divided into single meaning term and refined as typical term, using the inclusive effect terms I established. After that, herbs were grouped by tastes and found the effect terms which are mentioned most frequently. And it could be supposed to be classified into each herb's new effects based on the relationship between properties and those effect terms. It is also inferred into new tastes from some herbs by analysing the representative effects group of each taste and finding which other tastes can be related to each herb's effect. Result & Conclusion : All the superficies-resolving herbs can have wind-dispelling effect and superficies-resolving effect, except Bulpleuri Radix. This herb is able to has just the wind-dispelling effect. And it's more appropriate to categorize Bulpleuri Radix to heat-clearing herb group than superficies-resolving herb group, considering its several, distinctly cold characteristics. Some effects are concentrated to wind-cold-dispersing herb group and others to wind-heat-dispersing herb group. Each tastes has its own representative effect group. And, according to its tastes' representative effect, some of herbs are reasonable to get new effect term. With not so feasible reason, 4 kinds of herbs are supposed to contain all of hot, bitter, and sweet tastes. Also It's needed to study much deeper whether Perillae Herba, Zingiberis Rhizoma Crudus and Elsholtziae Herba are belong to superficies-resolving herb group or to interior-warming or damp-dissolving aromatic herb group.