• Genomics & Informatics
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• 제6권3호
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• pp.157-159
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• 2008

Multiple sequence alignment (MSA) is the most important step for many of biological sequence analyses, homology search, and protein structural assignments. However, large amount of data make biologists difficult to perform MSA analyses and it requires much computational time to align many sequences. Here, we have developed a simple and fast web alignment tool for aligning, editing, and visualizing large amount of sequence data. We used a cluster server installed ClustalW-MPI using web services and message passing interface (MPI). It also enables users to edit multiple sequence alignments for manual editing and to download the input data and results such as alignments and phylogenetic tree.

• International Journal of Naval Architecture and Ocean Engineering
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• 제4권3호
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• pp.211-227
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• 2012

To implement a combined discrete event and discrete time simulation such as submarine diving simulation in a distributed environment, e.g., in the High Level Architecture (HLA)/Run-Time Infrastructure (RTI), a HLA interface, which can easily connect combined models with the HLA/RTI, was developed in this study. To verify the function and performance of the HLA interface, it was applied to the submarine dive scenario in a distributed environment, and the distributed simulation shows the same results as the stand-alone simulation. Finally, by adding a visualization model to the simulation and by editing this model, we can confirm that the HLA interface can provide user-friendly functions such as adding new model and editing a model.

• 대한전기학회논문지
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• 제36권2호
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• pp.129-139
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• 1987

In this paper the programming language for Hero-1 robot is developed using Apple II micro computer. The language is composed of main monitor mode, editing mode, execution mode, and debugging mode. The main monitor mode is a main flow of the whole language system and controls starting and terminating procedures of operating the controller, and monitors the others. The editing mode has capability to make a user's maniqulation program. Trajectory planning algorithms(point-to-point motion and linear approximate motion)have been realized in the robot language, and in the case of point-to-point motion, inverse kinematics have been solved for the desired point.

• 한국조경학회지
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• 제23권1호
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• pp.23-38
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• 1995

ELEECTRE is a less demanding and potentially Bffective multiattribute evaluation method for pre-editing proeedure. The method, however, was developed based on probabilistic mathematicsand its reliability has never'been emprieally tested. This article examined the reliability of ELECTRo under various conditions of linear and non-linear utility func- tions using a Monte-Carlo shnulation, and found the method eausea a considerably high rate of error. To enhance the reliability of ELECTRE, two ways of modi(ication - adjust- ment of threshold values of concordance and discordance matrices, and adjustment of the required nunlber of probably-dominant alternatives to eliminate a probably-dominated alternative - were suggested, and their effctiveness was also tesed by a Monte-Carlo simulation. The simulation result chows that these modifications cponsiderably improve the reliability of ELECTRE, and yet maintain a reasonably high level of efficiency. Through these modifications, ELECTRE can be used as an efficient and feliable pre-editing method. Ways to implement ELECTRE in the construction of plainning decision support systens were discussed. The impli(els combination of this method and other multiattribute evaluation methods will help to create more effective decision suport systems.

• 디자인학연구
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• 제12권4호
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• pp.15-22
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• 1999

그 동안 활자인쇄매체의 타이포그래피의 적용에 관한 연구는 활발하였고 또 그 연구를 바탕으로 디자인에 적용되어 왔다. 그러나 지면출력을 위한 편집디자인이 아닌 Web환경에서의 가상공간의 편집디자인을 활자인쇄매체에 적용되는 방법을 그대로 이용하고 있는 것이 현실 이였다. 그래서 본 논문에서는 Web상황에 타이포그래피을 적절히 적용시키기 위한 방법으로 리서치를 통한 Web상황에서의 바람직한 타이포그래피의 적용방법과 타이포그래피의 적용 한계점을 알아보고 그 것에 대한 대체방안을 논하고자 한다.

• Journal of Genetic Medicine
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• 제3권1호
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• pp.15-19
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• 1999

We have investigated the genetic variation in the human apo B mRNA editing protein (apobec-1) gene. Exon 3 of the apobec-1 gene was amplified by polymerase chain reaction. After detection of an additional band by single strand conformational polymorphism (SSCP) analysis, sequencing of the SSCP-shift sample revealed a single-base mutation. The mutation was a CGG transversion at codon 80 resulting in a lleRMet substitution. This substitution was confirmed by restriction fragment length polymorphism analysis since a Pvull site is abolished by the substitution. Population and family studies confirmed that the inheritance of the genotypes for apobec-1 gene polymorphism is controlled by two codominant alleles (P1 and P2). A significant difference in plasma triglyceride was detected among the different apobec-1 genotypes in the CAD patients (P<0.05). Our study could provide the basis for elucidating the interaction between genetic variation of the apobec-1 gene and disorders related to lipid metabolism.

• 한국정보통신학회논문지
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• 제13권2호
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• pp.243-252
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• 2009

본 논문에서는 유스케이스 기술서 작성 및 편집을 체계적으로 하기 위한 도구를 제시하고자 한다. 또한, 시나리오의 기술에 있어서 1컬럼 방식과 2컬럼 방식 모두를 지원하도록 하였으며, 시나리오 각 단계별 작성과 편집의 처리에 있어서 자동화된 단계 번호 때 기기를 지원하여 작성의 편의성을 높였다. 본 논문에서 제시하는 유스케이스 기술서 작성 도구는 편리하고 효과적으로 유스케이스 기술서를 작성하게 해 줄 뿐만 아니라, 유스케이스 다이어그램과 통합된 유스케이스 모델링 도구의 개발에 기여할 것으로 기대된다.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2019년도 춘계학술대회
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• pp.558-560
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• 2019

최근의 디지털 방송 서비스의 확대와 품질개선을 기반으로 첨단 방송 시비스의 지속적인 발전이 요구되고 있다. 본 논문에서는 초고속 데이터 링크 기술을 사용하여 앞에서 언급한 부분을 효율적으로 구현할 수 있는 한가지 방법을 제안하였다. 제안한 방법을 기존의 방법에 비해 처리속도가 개선되었으며, 다양한 형태의 컨텐츠를 효과적으로 편집할 수 있는 장점이 있다.

• Animal Bioscience
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• 제36권2_spc호
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• pp.333-338
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• 2023

Genetic modification enables modification of target genes or genome structure in livestock and experimental animals. These technologies have not only advanced bioscience but also improved agricultural productivity. To introduce a foreign transgene, the piggyBac transposon element/transposase system could be used for production of transgenic animals and specific target protein-expressing animal cells. In addition, the clustered regularly interspaced short palindromic repeat-CRISPR associated protein 9 (CRISPR-Cas9) system have been utilized to generate chickens with knockout of G0/G1 switch gene 2 (G0S2) and myostatin, which are related to lipid deposition and muscle growth, respectively. These experimental chickens could be the invaluable genetic resources to investigate the regulatory pathways and mechanisms of improvement of economic traits such as fat quantity and growth. The gene-edited animals could also be applicable to the livestock industry.

• Animal Bioscience
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• 제36권2_spc호
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• pp.339-349
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• 2023

Gene editing (GE) offers a new breeding technique (NBT) of sustainable value to animal agriculture. There are 3 GE working sites covering 5 feasible pathways to generate GE pigs along with the crucial intervals of GE/genotyping, microinjection/electroporation, induced pluripotent stem cells, somatic cell nuclear transfer, cryopreservation, and nonsurgical embryo transfer. The extension of NBT in the new era of pig breeding depends on the synergistic effect of GE and reproductive biotechnologies; the outcome relies not only on scientific due diligence and operational excellence but also on the feasibility of application on farms to improve sustainability.