• 정보처리학회논문지D
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• 제13D권7호
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• pp.977-984
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• 2006

본 연구는 RFID를 이용하여 특수의약품의 생산, 유통, 병원으로 이어지는 약품의 흐름을 추적 관리하는데 목적이 있다. 이는 유통과정에서 약품의 위변조를 막고, 유통흐름의 투명성을 제고하기 위해 의약품의 생산시점에 RFID Tag를 부착하여, 유통과정 각 단계에서 의약품의 흐름을 추적 관리하여 최종 사용자가 안심하고 사용할 수 있도록 한다. 또한 부가적으로 유통흐름상의 각 단계의 주체들에게 재고관리 정보를 제공하여 의약품 수급 및 관리에 대해 편의성을 제공하고 입출고 작업을 원활하게 수행할 수 있도록 한다. 본 연구는 의약품 분야에 FRID 적용가능성을 검토하는 연구로서 약품코드에 대한 RFID코드 표준안의 적용과 국산 미들웨어의 적용을 시도하였고 향후 의약품 분야의 이력관리를 할 수 있는 E-pedigree의 기초를 마련하고자 한다 또한 기술적으로 유통분야에 많이 쓰이는 90Mhz 대역의 리더 적용 및 약품에 적합한 RFID Tag의 설계 및 선정 결과를 제시한다.

• Journal of Animal Science and Technology
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• 제56권8호
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• pp.31.1-31.9
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• 2014

The objective of this study was to describe the population structure and inbreeding, and to quantify their effects on weights at different ages of Mehraban sheep in Iran. The analysis was based on the pedigree information of 26990 animals and 10278 body weight records from birth to yearling age. Data and pedigree information were collected during 1994 to 2011 by the breeding station of Mehraban sheep. The population structure was analyzed using the CFC program. Inbreeding of all animals was calculated by INBUPGF90 program. All animals were grouped into three classes according to their inbreeding coefficients: the first class included non-inbred animals (F=0); and the second and third classes included inbred animals (0$F{\geq}0.05$, respectively). The average inbreeding in Mehraban sheep was 1.69%. Founder equivalent ($f_e$) values were estimated to be 4244, 3116 and 2965 during 1994-1999, 2000-2005 and 2006-2011, respectively. The effective population sizes ($N_e$) were 363, 5080 and 5740 during 1994-1999, 2000-2005 and 2006-2011, respectively. Generation interval was 2.15 years for this breed of sheep. Regression coefficients of birth weight, 3-month weight, 6-month weight and yearling weight on lamb inbreeding were estimated to be -6.340.69, -14.685.33, 48.009.43 and 98.6515.65, respectively. Both positive and negative inbreeding effects were found in the current study. The utilization of a program for designed mating system, in the present flock, could be a suitable approach to keep the level of inbreeding under control.

• 한국육종학회지
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• 제40권4호
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• pp.525-528
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• 2008

기존 수출선인장인 비모란과 산취와는 구색과 형태과 다른 새로운 수출선인장 육성을 목표로 Copiapoa 속의 종간 교배조합인 $GCP563{\times}GCP618$ 조합에서 구색이 선명한 적갈색이고 조직돌기형의 결각을 갖은 GCP04571에 대한 농가실증시험 및 품평회를 마치고 명명된 "Red Stone"의 구색은 적갈색이고 결각의 형태는 돌기형으로 관상가치가 우수하며, 구의 형태는 원형으로 14개의 결각을 가지며, 자구수는 26.8개로 생산력이 우수하였다.

• 한국육종학회지
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• 제40권4호
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• pp.521-524
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• 2008

기존 산취계통은 자구 탈립이 잘되고 저장성이 낮으며 구색의 퇴화가 빠른 단점 등을 보완하고자 GC013001${\times}$GC0110703 조합에서 구색이 선명한 황색이고 관상가치가 우수한 GC052209 계통에 대한 농가실증시험 및 품평회를 마치고 명명된 "Yellow Tree"의 구색은 황색이었고 결각의 형태는 둥근형으로 관상가치가 우수하였으며, 구의 형태는 원형으로 8~9개의 결각을 가졌다. 가시는 갈색으로 반직립 하였으며 가시길이는 짧았다. 자구수는 개로 생산력이 우수하였다.

• Animal Bioscience
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• 제34권7호
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• pp.1116-1122
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• 2021

Objective: The aim was to characterize the genetic diversity evolution of the registered Mexican Charolais cattle population by pedigree analysis. Methods: Data consisted of 331,390 pedigree records of animals born from 1934 to 2018. Average complete generation equivalent, generation interval, effective population size (N_e), and effective numbers of founders (f_e), ancestors (f_a), and founder genomes (N_g) were calculated for seven five-year periods. The inbreeding coefficient was calculated per year of birth, from 1984 to 2018, whereas the gene contribution of the most influential ancestors was calculated for the latter period. Results: Average complete generation equivalent consistently increased across periods, from 4.76, for the first period (1984 through 1988), to 7.86, for the last period (2014 through 2018). The inbreeding coefficient showed a relative steadiness across the last seventeen years, oscillating from 0.0110 to 0.0145. During the last period, the average generation interval for the father-offspring pathways was nearly 1 yr. longer than that of the mother-offspring pathways. The effective population size increased steadily since 1984 (105.0) and until 2013 (237.1), but showed a minor decline from 2013 to 2018 (233.2). The population displayed an increase in the f_a since 1984 and until 2008; however, showed a small decrease during the last decade. The effective number of founder genomes increased from 1984 to 2003, but revealed loss of genetic variability during the last fifteen years (from 136.4 to 127.7). The f_a:f_e ratio suggests that the genetic diversity loss was partially caused by formation of genetic bottlenecks in the pedigree; in addition, the N_g:f_a ratio indicates loss of founder alleles due to genetic drift. The most influential ancestor explained 1.8% of the total genetic variability in the progeny born from 2014 to 2018. Conclusion: Inbreeding, N_e, f_a, and N_g are rather beyond critical levels; therefore, the current genetic status of the population is not at risk.

• Asian-Australasian Journal of Animal Sciences
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• 제30권2호
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• pp.149-153
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• 2017

Objective: This study was to determine the relationship between estimated breeding value and phenotype information after farrowing when juvenile selection was made in candidate pigs without phenotype information. Methods: After collecting phenotypic and genomic information for the total number of piglets born by Landrace pigs, selection accuracy between genomic breeding value estimates using genomic information and breeding value estimates of best linear unbiased prediction (BLUP) using conventional pedigree information were compared. Results: Genetic standard deviation (${\sigma}_a$) for the total number of piglets born was 0.91. Since the total number of piglets born for candidate pigs was unknown, the accuracy of the breeding value estimated from pedigree information was 0.080. When genomic information was used, the accuracy of the breeding value was 0.216. Assuming that the replacement rate of sows per year is 100% and generation interval is 1 year, genetic gain per year is 0.346 head when genomic information is used. It is 0.128 when BLUP is used. Conclusion: Genetic gain estimated from single step best linear unbiased prediction (ssBLUP) method is by 2.7 times higher than that the one estimated from BLUP method, i.e., 270% more improvement in efficiency.

• Asian-Australasian Journal of Animal Sciences
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• 제25권8호
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• pp.1063-1072
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• 2012

Effective population size ($N_e$) is an important measure to understand population structure and genetic variability in animal species. The objective of this study was to estimate $N_e$ in Sapsaree dogs using the information of rate of inbreeding and genomic data that were obtained from pedigree and the Illumina CanineSNP20 (20K) and CanineHD (170K) beadchips, respectively. Three SNP panels, i.e. Sap134 (20K), Sap60 (170K), and Sap183 (the combined panel from the 20K and 170K), were used to genotype 134, 60, and 183 animal samples, respectively. The $N_e$ estimates based on inbreeding rate ranged from 16 to 51 about five to 13 generations ago. With the use of SNP genotypes, two methods were applied for $N_e$ estimation, i.e. pair-wise $r^2$ values using a simple expectation of distance and $r^2$ values under a non-linear regression with respective distances assuming a finite population size. The average pair-wise $N_e$ estimates across generations using the pairs of SNPs that were located within 5 Mb in the Sap134, Sap60, and Sap183 panels, were 1,486, 1,025 and 1,293, respectively. Under the non-linear regression method, the average $N_e$ estimates were 1,601, 528, and 1,129 for the respective panels. Also, the point estimates of past $N_e$ at 5, 20, and 50 generations ago ranged between 64 to 75, 245 to 286, and 573 to 646, respectively, indicating a significant $N_e$ reduction in the last several generations. These results suggest a strong necessity for minimizing inbreeding through the application of genomic selection or other breeding strategies to increase $N_e$, so as to maintain genetic variation and to avoid future bottlenecks in the Sapsaree population.

• 한국작물학회지
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• 제66권4호
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• pp.443-451
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• 2021

Finger millet (Eleusine coracana) is widely cultivated in tropical regions worldwide owing to its high nutritional value. Finger millet is more tolerant against biotic and abiotic stresses such as pests, drought, and salt than other millet crops; therefore, it was proposed as a candidate crop to adapt to climate change in Korea. In 2019, we used expressed sequence tag simple sequence repeat (EST-SSR) markers to evaluate the genetic diversity and structure of 102 finger millet accessions from two geographical regions (Africa and South Asia) to identify appropriate accessions and enhance crop diversity in Korea. In total, 40 primers produced 116 alleles, ranging in size from 135 to 457 bp, with a mean polymorphism information content (PIC) of 0.18225. Polymorphism was detected among the 40 primers, and 13 primers were found to have PIC values > 0.3. Principal coordinate and phylogenetic analyses, based on the combined data of both markers, grouped the finger millet accessions according to their respective collection areas.Therefore, the 102 accessions were classified into two groups, one from Asia and the other from Africa. We have conducted an in-depth study on the finger millet landrace pedigree. By sorting out and using the molecular characteristics of each pedigree, it will be useful for the management and accession identification of the plant resource. The novel SSR markers developed in this study will aid in future genetic analyses of E. coracana.

• 농업과학연구
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• 제41권1호
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• pp.41-46
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• 2014

본 연구는 국내 주요 두록 종돈장의 혈통자료를 이용하여 근교수준과 유효집단 크기를 추정하기 위해 수행하였다. 혈연관계를 가지기 시작한 1987년부터 2013년까지 총 86,639두의 혈통자료를 최종적으로 이용하여 6개 종돈장의 세대별 근교계수 및 유효집단크기를 추정하였다. 종돈장별 세대에 따른 근교계수 변화는 2가지 패턴으로 조사되었으며, 근교계수 평균은 5% 이내로 적절한 수준을 유지하는 것으로 사료된다. 유효집단 크기는 종돈장별 다양한 차이를 보였지만 모든 종돈장이 최소권장수준인 50두 이상으로 유지하는 것으로 분석되었다. 대부분의 종돈장이 낮은 근교수준을 유지하는 것으로 조사되었는데, 근교계수를 고려한 교배관리와 외부 종돈 도입이 주된 원인이라 사료된다. 외부 종돈을 수입해서 도입하는 경우, 집단의 유전적 다양성은 증가할 수 있지만, 향후 국제적 종자주권 행사에는 불리한 상황이 될 수 있다. 특히 나고야의정서의 ABS(Access, Benefit, Sharing) 규정(2010)에 따라 유전자원을 제공하는 업체나 국가가 종자 주권 행사에 유리하도록 전개되고 있다. 그리고 업체상호 간 계약합의가 국제거래 규약의 효력을 가지기 때문에 정액, 자손 등 종자의 사후활용에 대해서도 로열티를 요구할 수 있다. 따라서 유효집단 크기를 높이기 위한 방법으로 무분별한 수입보다는 국내 종돈장 사이에서 우수 종돈을 공유하는 것이 필요할 것으로 사료된다.

• 한국육종학회지
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• 제42권6호
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• pp.717-720
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• 2010

경기도농업기술원 선인장연구소에서는 다육식물 내수시장 확대를 위하여 1998년부터 국내의 재배농가와 종묘업체로부터 유전자원을 수집한 후 2001년부터 2009년에 걸쳐 교배 및 계통선발을 하고 3회의 특성검정을 거쳐서 꽃기린 신품종 '파노라마'를 육성하였다. 기존 꽃기린 품종은 포화엽색이 적색, 분홍색 등 단색인 품종이었으나 새로 육성된 '파노라마' 품종은 포화엽색이 녹색과 분홍색(RHS color chart 135B+54C)이 어우러진 복색이면서 고급스런 색체의 이미지를 준다. 측지수는 4.3개 발생하며 포화엽폭은 2.0 cm로 대륜성 품종이다. 줄기에 꽃차례 분지단수가 2~3개로 많이 발생하는 다화성으로 관상가치가 우수한 품종이다.