• Title/Summary/Keyword: dyploid

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ON THE ADAPTED EQUATIONS IN VARIOUS DYPLOID MODEL AND HARDY-WEINBURG EQUILIBRIUM IN A TRIPLOID MODEL

  • Won Choi
    • Korean Journal of Mathematics
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    • v.31 no.1
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    • pp.17-23
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    • 2023
  • For a locus with two alleles (IA and IB), the frequencies of the alleles are represented by $$p=f(I^A)={\frac{2N_{AA}+N_{AB}}{2N}},\;q=f(I^B)={\frac{2N_{BB}+N_{AB}}{2N}}$$ where NAA, NAB and NBB are the numbers of IAIA, IAIB and IBIB respectively and N is the total number of populations. The frequencies of the genotypes expected are calculated by using p2, 2pq and q2. Choi defined the density and operator for the value of the frequency of one gene and found the adapted partial differential equation as a follow-up for the frequency of alleles and applied this adapted partial differential equation to several diploid model [1]. In this paper, we find adapted equations for the model for selection against recessive homozygotes and in case that the alley frequency changes after one generation of selection when there is no dominance. Also we consider the triploid model with three alleles IA, IB and i and determine whether six genotypes observed are in Hardy-Weinburg for equilibrium.

ON THE GENOTYPE FREQUENCIES AND GENERATING FUNCTION FOR FREQUENCIES IN A DYPLOID MODEL

  • Choi, Won
    • Korean Journal of Mathematics
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    • v.29 no.1
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    • pp.75-80
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    • 2021
  • For a locus with two alleles (IA and IB), the frequencies of the alleles are represented by $$p=f(I^A)={\frac{2N_{AA}+N_{AB}}{2N} },\;q=f(I^B)={\frac{2N_{BB}+N_{AB}}{2N}}$$ where NAA, NAB and NBB are the numbers of IA IA, IA IB and IB IB respectively and N is the total number of populations. The frequencies of the genotypes expected are calculated by using p2, 2pq and q2. So in this paper, we consider the method of whether some genotypes is in Hardy-Weinburg equilibrium. Also we calculate the probability generating function for the offspring number of genotype produced by a mating of the ith male and jth female under a diploid model of N population with N1 males and N2 females. Finally, we have conditional joint probability generating function of genotype frequencies.

ON THE ADAPTED EQUATIONS FOR SEVERAL DYPLOID MODEL IN POPULATION GENETICS

  • Choi, Won
    • Korean Journal of Mathematics
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    • v.30 no.1
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    • pp.67-72
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    • 2022
  • For a locus with two alleles (IA and IB), the frequencies of the alleles are represented by $$p=f(I^A)={\frac{2N_{AA}+N_{AB}}{2N},\;q=f(I^B)={\frac{2N_{BB}+N_{AB}}{2N}$$ where NAA, NAB and NBB are the numbers of IAIA, IAIB and IBIB respectively and N is the total number of populations. The frequencies of the genotypes expected are calculated by using p2, 2pq and q2. Choi showed the method of whether some genotypes is in these probabalities. Also he calculate the probability generating function for offspring number of genotype under a diploid model( [1]). In this paper, let x(t, p) be the probability that IA become fixed in the population by time t-th generation, given that its initial frequency at time t = 0 is p. We find adapted equations for x using the mean change of frequence of alleles and fitness of genotype. Also we apply this adapted equations to several diploid model and it also will apply to actual examples.