• 제목/요약/키워드: duplication methods

검색결과 140건 처리시간 0.026초

초등과학 영재학급 담당 교사의 영재 교육에 대한 인식 조사 (A Survey on Teachers' Perceptions of Gasses for the Science Gifted in Elementary School)

  • 최선영
    • 한국초등과학교육학회지:초등과학교육
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    • 제26권3호
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    • pp.252-259
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    • 2007
  • The purpose of this study was to examine the status and science teachers' perceptions of classes for those gifted in science in elementary school. For this purpose, a number of questions were posed to teachers : 27-item-questionnaires were given to 38 teachers of students gifted in science in elementary schools located in Incheon province. The results of this study were as follows : 1. most elementary teachers were in charge of classes containing students gifted in science, but this was the case with only a few secondary teachers. Therefore, it appears to be more necessary to educate elementary teachers who majored in science content and gifted education. 2. In addition, most teachers had positive perceptions of the needs, attitudes and environments needed for gifted education. Most of them attended 60-hour training programs on gifted education. They thought that it was helpful in understanding the characteristics of gifted students, but they wanted to learn more about actual pedagogical methods through such programs. 3. The teaching methods used in classes for those gifted in science were mainly experimental activities, but there were few opportunities for creative problem solving and project learning. This may be due to limited class time of about one hour every two weeks in this class. 4. When the materials used in class were first developed, they mainly used materials made by the city board of education and selected the theme of interest by themselves. Therefore, there may be problems of duplication of materials or systems regarding the science contents for one year. 5. Furthermore, the themes of the materials used were mostly related in terms of the contents of textbooks than more generally. When planning and managing the classes for those gifted in science, the above points should be considered in order to improve the education of those students gifted in science.

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FLT3-ITD 검출을 위한 절편분석법: 일반 중합효소연쇄반응 및 직접염기서열분석법과의 비교 (Fragment Analysis for Detection of the FLT3-Internal Tandem Duplication: Comparison with Conventional PCR and Sanger Sequencing)

  • 이건동;김정은;이상윤;장우리;박준홍;채효진;김명신;김용구
    • Laboratory Medicine Online
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    • 제7권1호
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    • pp.13-19
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    • 2017
  • 배경: 저자들은 FLT3-ITD (fms-like tyrosine kinase-internal tandem duplication) 돌연변이의 정량 및 반복 염기 길이를 동시에 측정하는 정량 절편 분석법(fragment analysis)의 민감도를 평가하고, 분석적 성능을 검증하였다. 방법: FLT3-ITD 돌연변이의 정량과 수는 절편분석법으로 측정하였다. 변이 대립유전자와 정상 대립유전자를 혼합한 계대희석 표준물질로 절편 분석법, 일반 PCR법, 염기서열분석법의 FLT3-ITD 변이 검출한계를 측정하였다. 정상 공여자 50검체를 이용하여 특이도를 평가하였다. 급성골수성백혈병 환자의 481검체에 대하여 절편 분석법과 일반 PCR법으로 검사를 시행하고 그 결과를 비교 분석하였다. 결과: 절편 분석법의 돌연변이 최소 검출 농도는 5%였으며, 일반 PCR 검사법과 직접염기서열분석법은 각각 10%, 20%의 결과를 보였다. 급성골수성백혈병 환자의 481 검체를 분석한 결과, FLT3-ITD는 40.1% (193/481)에서 양성이었다. 변이 대립유전자의 정량값은 1.7-94.1% (중앙값 28.2%)로 다양하였으며, 반복 염기의 길이의 범위는 14bp-153 bp (중앙값 49bp)였다. 일반 PCR 검사법과 비교한 결과 방법간 일치도는 97.7% (470/481)였다. 절편 분석법이 일반 PCR 검사법에 비해 더 높은 민감도를 보였고, 11건의 돌연변이가 더 검출되었다. 이 중 7검체는 변이 대립유전자의 양이 10% 미만으로 일반 PCR 검사에서 검출되지 않았다(3.3-9.5%). 또 다른 불일치 세 검체에서는 PCR inhibitor의 영향으로 일반 PCR 방법에서 위음성 결과를 보였으며, 다른 한 검체는 돌연변이 중복 길이가 14 bp로 매우 짧아 일반 PCR에서 정상 밴드와 구별되지 않는 경우였다. 결론: 본 연구에서 저자들이 사용한 절편 분석법은 FLT3-ITD 돌연변이의 정량값과 중복된 길이를 동시에 측정할 수 있는 검사법으로, 민감하고 정확하여 급성골수성백혈병 환자에서 FLT3-ITD의 진단 및 추적 검사에 유용할 것으로 기대된다.

의약품 처방·조제지원서비스(Drug Utilization Review)사업이 병용금기 처방률에 미치는 영향 (The Effect of Korean Prospective Drug Utilization Review Program on the Prescription Rate of Drug-Drug Interactions)

  • 김동숙;박주희;전하림;박찬미;강현아
    • 보건행정학회지
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    • 제24권2호
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    • pp.120-127
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    • 2014
  • Background: Since December 2010, online computerized prospective drug utilization review (pDUR) has been implemented in Korea. pDUR involves the review of each prescription before the medication is dispensed to the individual patient. The pDUR is performed electronically by Health Insurance Review & Assessment Service (HIRA), which is a Korean governmental agency, and then HIRA provides medical institutions and pharmacies with information that can be helpful to them in preventing potential drug problems such as drug/drug interactions or ingredient duplication. The aim of this study was to assess the impact of the Korean pDUR implementation on the proportion of drug-drug interactions (DDIs) using claims data from HIRA. Methods: A before-after comparison of the prevalence of DDIs between prescription was conducted, using HIRA administrative claims data of medical institution from January 2010 to December 2011. The analysis unit was the prescription issued and pairs before and after. The main outcome measures were the proportion of DDIs within- (control group) or between- physician encounters. To examine the difference, a paired t-test was applied. Results: We found that DDIs proportion between prescription decreased significantly (t=3.04, p=0.0026) after the implementation of pDUR, whereas there is no significant reduction within prescription (t=1.15, p=0.2518). With respect to the prevalence of DDIs between drug groups, the most dramatic reduction was occurred between 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors and anti-fungal agents. Conclusion: It seems effective that giving a direct feedback to prescribers by a prospective DUR. Further research is needed to assess the impact of DUR to final outcomes such as hospitalization.

아로마테라피가 중년여성의 갱년기 증상, 스트레스 및 우울에 미치는 효과: 체계적 문헌고찰 (Effects of Aromatherapy on Menopausal Symptoms, Perceived Stress and Depression in Middle-aged Women: A Systematic Review)

  • 김신미;송지아;김미은;허명행
    • 대한간호학회지
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    • 제46권5호
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    • pp.619-629
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    • 2016
  • Purpose: This study was a systematic review to evaluate the effects of aromatherapy on menopausal symptoms, perceived stress and depression in middle aged-women. Methods: Eight databases were searched from their inception September 8, 2015. Two reviewers independently performed the selection of the studies, data abstraction and validations. The risk of bias was assessed using Cochrane criteria. For analysis of the data, a meta-analysis of the studies was performed. Results: From the electronic databases, 73 articles were selected, and 19 removed due to duplication. After two reviewers read the abstracts of 54 studies, 34 studies were selected. Complete papers for 34 s were read and, 12 studies which met selection criteria were reviewed and the effects of aromatherapy on menopausal symptoms, stress and depression analyzed using meta-analysis with RevMan. In the 2 studies which included Randomized Controlled Trials testing of aromatherapy on menopausal symptoms and comparison of control and placebo groups were done. Aromatherapy massage was favorably effective in reducing the menopausal symptoms compared to the control group (n=118, MD=-6.33; 95% CI -11.51 to -1.15), and compared to the placebo group (n=117, MD=-4.14; 95% CI -7.63 to -0.64). Also aromatherapy was effective in reducing stress (n=72, SMD=-0.64; 95% CI -1.12 to -0.17) and depression (n=158, MD=-5.63; 95% CI -10.04 to -1.22). Conclusion: There is limited evidence suggesting that aromatherapy for middle-aged women may be effective in controlling menopausal symptoms, perceived stress and depression.

데이터베이스 정규화 이론을 이용한 국민건강영양조사 중 다년도 식이조사 자료 정제 및 통합 (Data Cleaning and Integration of Multi-year Dietary Survey in the Korea National Health and Nutrition Examination Survey (KNHANES) using Database Normalization Theory)

  • 권남지;서지혜;이헌주
    • 한국환경보건학회지
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    • 제43권4호
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    • pp.298-306
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    • 2017
  • Objectives: Since 1998, the Korea National Health and Nutrition Examination Survey (KNHANES) has been conducted in order to investigate the health and nutritional status of Koreans. The food intake data of individuals in the KNHANES has also been utilized as source dataset for risk assessment of chemicals via food. To improve the reliability of intake estimation and prevent missing data for less-responded foods, the structure of integrated long-standing datasets is significant. However, it is difficult to merge multi-year survey datasets due to ineffective cleaning processes for handling extensive numbers of codes for each food item along with changes in dietary habits over time. Therefore, this study aims at 1) cleaning the process of abnormal data 2) generation of integrated long-standing raw data, and 3) contributing to the production of consistent dietary exposure factors. Methods: Codebooks, the guideline book, and raw intake data from KNHANES V and VI were used for analysis. The violation of the primary key constraint and the $1^{st}-3rd$ normal form in relational database theory were tested for the codebook and the structure of the raw data, respectively. Afterwards, the cleaning process was executed for the raw data by using these integrated codes. Results: Duplication of key records and abnormality in table structures were observed. However, after adjusting according to the suggested method above, the codes were corrected and integrated codes were newly created. Finally, we were able to clean the raw data provided by respondents to the KNHANES survey. Conclusion: The results of this study will contribute to the integration of the multi-year datasets and help improve the data production system by clarifying, testing, and verifying the primary key, integrity of the code, and primitive data structure according to the database normalization theory in the national health data.

원본정보 없이 씰영상의 추출이 가능한 이미지 워터마킹 기법 (A Watermarking Scheme to Extract the Seal Image without the Original Image)

  • 김원겸;이종찬;이원돈
    • 한국정보처리학회논문지
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    • 제7권12호
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    • pp.3885-3895
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    • 2000
  • 디지털 이미지 기법과 디지털 네트웍의 출현으로 예술적 작품의 복사가 더욱 쉬워지고 있다. 이러한 창작품을 보호하기 위해 데이터 안에 저작권을 표시할 수 있는 표식이나 인식 가능한 데이터를 삽입하는 기술이 필요해지고 있고 지난 몇 년간 디지털 이미지나 오디오, 비디오 등의 멀티미디어 데이터에 저작권을 표시하기 위한 데이터나 기타 다른 정보를 삽입할 수 있는 많은 기법들이 제안되어 왔다. 본 논문에서는 이미지의 주파수 영역에 인식 가능한 패턴을 삽입하고 추출하는 워트마킹 기법을 제안한다. 또한 삽입된 워터마크를 원본이미지의 정보 없이 추출할 수 있도록 하여 임의의 사람이 워터마크 된 이미지로부터 가짜원본을 생성하는 것이 어렵도록 한다. 원본정보 없이 워터마크를 추출하기 위해서 화소의 원래 값을 예측하는 방법을 사용한다. 예측기법은 구하고자 하는 화소의 주위값을 평균한다는 것을 의미한다. 부가적으로 워터마크를 이미지 주파수 영역에 삽입함으로써 JPEG같은 손실압축바업에도 견딜 수 있도록 한다.

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블로그 서비스 시스템을 위한 효과적인 중복문서의 검출 기법 (An Efficient Method for Detecting Duplicated Documents in a Blog Service System)

  • 이상철;이순행;김상욱
    • 한국정보과학회논문지:데이타베이스
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    • 제37권1호
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    • pp.50-55
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    • 2010
  • 블로그 서비스 시스템에 존재하는 중복문서는 블로그 검색의 서비스 질과 성능을 저하시키는 요인 중 하나이다. 기존의 웹 페이지 환경에서와는 달리, 블로그 서비스 시스템에서는 각 문서의 생성이 매번 보고되기 때문에 문서 생성 시점에 중복 판정이 가능하다. 본 논문에서는 이 점에 착안하여 문서를 저장하는 시점에 해당 문서의 중복 여부를 판정하는 새로운 중복문서 검출 기법을 제안한다. 제안된 기법을 통하여 검출된 중복문서는 검색 엔진을 위한 인덱싱에 반영시키지 않음으로써 중복문서가 검색 결과에 반영되는 문제를 원천적으로 방지할 수 있다. 또한, 효과적인 중복문서 검출을 위하여 3가지 인덱싱 기법을 제안하며, 실제 블로그 데이터를 이용하여 각 인덱싱 기법 중 가장 효율적인 기법을 보인다.

Study on the reorganization of the legal system for an integrated forestry business

  • Park, Chang-Won;Lee, Bo-Hwi;Joung, Da-Wou;Park, Bum-Jin;Lee, Joon-Woo;Kim, Se-Bin;Koo, Seung-Mo
    • 농업과학연구
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    • 제46권4호
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    • pp.755-768
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    • 2019
  • The forestry development policies and projects in Korea have been implemented under various related acts. These acts include the Framework Act on the National Land and Framework Act on Forestry enacted by each administration. However, there are some limitations to encourage a variety of mountain villages and forestry development policies due to duplication and overlap between the relevant acts. Nowadays, the fields of local development have evolved and become integrated not only by infrastructures but also in various fields such as multi-functional industries including tourism, green care, cultural welfare, etc. Therefore, the current legal system may not effectively accept and support various mountain village development policies and projects. This study tried to determine the necessity of reorganizing th-e related legal system through a field survey of planners, residents and analysts regarding the correlation between legal systems and projects. For these reasons, this study tried to determine the problems of the current legal system and then, suggested alternative methods related to the legal system for integrated rural development. The scope of the study is as follows: 1) correlation analysis between relevant laws and development projects and 2) field survey to determine the legitimacy and validity for the reorganization of the legal system.

A Q-methodological Study on Nursing Students' Attitudes toward Nursing Ethics

  • Yeun Eun-Ja;Kwon Young-Mi;Kim Hung-Kyu
    • 대한간호학회지
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    • 제34권8호
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    • pp.1434-1442
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    • 2004
  • Purpose. Professional nursing ethics is a living, dynamic set of standards for nurses' professional moral behavior. Furthermore, in daily clinical nursing training, nursing students are constantly confronted with decision-making that is moral in nature. The aim of this study was to identify the perceived ethical attitudes in the clinical training process of senior nursing students using Q-methodology to offer basic strategies for nursing ethics education and thereby improve patients' care. Methods. Q-methodology provides a scientific method for identifying perception structures that exist within certain individuals or groups. Thirty-seven participants in a university rated 38 selected Q-statements on a scale of 1-9. The collected data were analyzed using pc-QUNAL software. Results. Principal component analysis identified 3 types of ethical attitudes in nursing students in Korea. The categories were labeled Sacred-life, Science-realistic and Humane-life. Sacred-life individuals think that a life belongs to an absolute power (God), not a man, and a human life is a high and noble thing. Science-realistic individuals disagreed that allowing an induced abortion or embryo (human) duplication is unethical behavior that provokes a trend, which takes the value of a life lightly; most of them took a utilitarian position with respect to ethical decisions. Humane-life individuals exhibit a tendency toward human-centered thought with respect to ethical attitudes. Conclusion. This study will be of interest to educators of students of nursing and hospital nursing administrators. Also, the findings may provide the basis for the development of more appropriate strategies to improve nursing ethics education programs.

한.중.일 목조 불탑의 비교론적 고찰(I) - 귀공포를 중심으로 - (A Comparative Study Wooden Stupa of Korea, Japan and China(I) - Focused on the Corner Bracket Set -)

  • 천득염;양태현;이재연
    • 건축역사연구
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    • 제21권2호
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    • pp.7-20
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    • 2012
  • As the corner of wooden pagoda forms the roof by closely bordering left and right eaves on the various purlins and angle rafters, it is designed for every face to be recognized as front whose structure system increases load to bear proportionally. The corner of wooden pagoda is inseparable with the corner bracket set as it becomes stable thanks to the corner bracket set structurally and load burden under restrained structure makes the corner bracket set really important. Accordingly, this study could figure out some facts by analyzing corner bracket sets of Palsangjeon of Beobjusa Temple in Korea, Seokgatap of Bulgungsa Temple in China and Ojungtap of Beobryungsa Temple in Japan which were constructed with pure wooden structure. This study demonstrated that corner bracket set played a pivotal role in keeping balance of concentrated load of corner (corner of opening) in each floor that contributed to the stability of wooden pagoda structurally despite multiple duplications of floors and also figured out the outfit of corner bracket set was subject to the floor type and the cross section of Gongpo installed on top of Pyeongju. Wooden pagodas in 3 countries were two floor types of octagon and square, and employed different connection method between upper and lower floors. The difference between floor and duplication method determines the method of corner, but even different methods were sufficient to have entirety in every side by completing dynamic principle of corner bracket set even though old method had to solve the problem of concentrated load and it also confirms that it was essential Gongpo to prevent any deformation of corner.