• Journal of Trauma and Injury
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• 제25권3호
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• pp.94-96
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• 2012

Duodenal injuries following a blunt or penetrating trauma are uncommon and account for just 3% to 5% of all abdominal injuries. About 22% of all duodenal injuries are caused by blunt trauma. An overlooked injury or delayed diagnosis of duodenal injury may lead to increased mortality and morbidity. We report two cases of a duodenal injury following blunt abdominal trauma.

• Journal of Trauma and Injury
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• 제34권1호
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• pp.70-74
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• 2021

There are many possible causes of duodenal obstruction, such as congenital anomalies and various acquired conditions associated with space-occupying lesions. However, hemorrhage or retroperitoneal hematoma is a rare cause of duodenal obstruction. Here, we report the case of a 55-year-old man who developed duodenal obstruction due to a large retroperitoneal hematoma after acupuncture therapy. The patient experienced abdominal discomfort along with vomiting and nausea. Considering the size of the hematoma, emergency surgery could have been performed, but conservative treatment was continued because the patient's vital signs were stable. With spontaneous resolution of the hematoma, the symptoms of duodenal obstruction improved. The patient was eventually discharged without any complications associated with the hematoma. Our findings suggest that even when a hematoma is large, a conservative approach can be maintained until improvement of the symptoms of duodenal obstruction if the vital signs of the patient remain stable.

• Journal of Trauma and Injury
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• 제33권1호
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• pp.53-58
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• 2020

Duodenal injury following blunt abdominal trauma is a relatively unusual complication, and it may sometimes be difficult to distinguish a duodenal hematoma from duodenal perforation. According to recent reports, intramural hematomas typically resolve spontaneously with conservative treatment. Surgery, however, is occasionally necessary in some cases if the diagnosis is delayed, conservative therapy fails, or a high degree of suspicion of duodenal injury persists. We experienced a case of delayed manifestation of a duodenal intramural hematoma that was surgically treated.

• Journal of Trauma and Injury
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• 제25권4호
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• pp.271-274
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• 2012

Duodenal perforation has a high incidence of complications and mortality if not detected and treated early. Delayed diagnosis of duodenal perforation is frequent because patients rarely complain of any symptoms. We report a case of duodenal perforation that appeared after trauma and was cured by using conservative treatment.

• BMB Reports
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• 제31권3호
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• pp.274-280
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• 1998

An inositol monophosphatase (IMPase) was purified to homogeneity from rat duodenal mucosa for the first time and its enzymatic properties were investigated. Rat duodenal mucosa peculiarly exhibited the highest IMPase activity among various rat tissues examined. By means of ammonium sulfate precipitation, followed by Q-Sepharose, polylysine agarose, reactive-red agarose column chromatography, Uno-Q FPLC, and Bio-Silect FPLC, duodenal IMPase was purified 223-fold to a specific activity of 13.6 U/mg protein. The molecular mass of the native enzyme was estimated to be 48,000 Da on gel filtration. The subunit molecular mass was determined by SDS-PAGE to be 24,000 Da. These results indicate that duodenal IMPase is a dime ric protein made up of identical subunits. Rat duodenal IMPase has distinct properties from brain IMPase. It has a broad spectrum of substrate specificity and is insensitive to $Li^+$. Duodenal IMPase does not absolutely require $Mg^{2+}$ for its catalytic activity. Furthermore, duodenal IMPase is less stable to heat than brain enzyme. It is suggested that the rat duodenal mucosa needs a large amount of IMPase whose properties are quite different from that of the brain enzyme.

• 보험의학회지
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• 제9권
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• pp.130-137
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• 1990

We'd performed the upper gastrointestinal study for a total of 10,047 insureds-male 5,919 female 4,128 persons-who were examined at medical department of Dae Han Kyoyuk Insurance Co., from August, 1986 to December, 1989. The results on duodenal ulcer were as follows; 1) Duodenal ulcer was found in 138 cases(1.37%) among the 10,047 insureds. 2) In all 138 cases who have duodenal ulcer, duodenal ulcer was found in 112 cases(1.89%) among the 5,919 insureds of male and in 26 cases(0.63%) among the 4,128 insureds of female. The incidence of duodenal ulcer in male was higher than in female. 3) The possessing rate of duodenal ulcer is 1.28% in 20 yrs, 1.24% in 30 yrs, 1.72% in 40 yrs, 1.21% in 50 yrs, 0.48% in 60 yrs. 4) The possessing rate of duodenal ulcer in male is 2.24% in 20 yrs, 1.78% in 30 yrs, 1.99% in 40 yrs, 2.05% in 50 yrs, 0.91% in 60 yrs and in female, 0.52% in 20 yrs, 0.48% in 30 yrs, 1.20% in 40 yrs, 0.2% in 50 yrs. 5) Coexistent lesion with duodenal ulcer were found in 19 cases; one case of esophageal diverticulum, one case of gastric diverticulum, one case of duodenal diverticulum, tow cases of gastric ulcer, six cases of gastritis, five cases of duodenitis, two cases of gastroduodenitis, one case of pseudodiverticulum.

• 대한세포병리학회지
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• 제2권2호
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• pp.105-110
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• 1991

We report a case of hepatoma with duodenal metastasis in a 53 year-old male patient. Hepatoma was confirmed by fine needle aspiration cytology technique, and duodenal metastasis by gastrofiberscopic biopsy. Duodenal metastasis of hepatoma is rare. We briefly review the role of fine needle aspiration cytology technique in diagnosis of hepatoma.

• Journal of Chest Surgery
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• 제30권12호
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• pp.1251-1253
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• 1997

개심 수술후 위장관 계통의 합병증은 드물게 발생하지만 사망률은 매우 높은 심각한 합병증 중의 하나이 며 특히 십이지장의 합병증은 그 빈도가 매우 드문 것으로 알려져 있다. 본원에서는 개심 수술후 십이지장 출혈 1례, 십이지장 궤양 천공 2례를 치험하였다. 출혈의 경우 빈맥, 현기증, 흑색변 등의 증상이 임상적 의 심의 단서가 되었으며, 천공의 경우는 복통을 동반한 복부 팽만, 빈맥, 저혈압, 핍뇨 등이 임상적 단서가 되 었고 복막펀자술로 확진을 내릴 수 있었다. 십이지장 출혈의 경우 항제산제의 복용, 수혈 등 보존적인 방법 으로 치료되었으나 십이지장 천공의 경우에는 2례 모두에서 응급 개복수술을 필요로 하였고 1례는 병발되는 합병증으로 가퇴원하였으며, 나머지 1례에서는 장기간의 중환자실 처치를 필요로 하였다. 따라서 수술전 과 거력상 위장관 계통의 증상, 장시간의 심폐바이패스 사용등 위십이지장궤양의 위험인자가 있는 환자들에서 는 개심수술후 항궤양 약물의 예방적 사용뿐만 아니라 십이지장 합병증에 대한 임상적 의심, 조기 진단과 시의 적절한 치료가 십이지장 합병증의 이환율과 사망률을 줄이는데 필요한 것으로 생각된다.

• 대한지역사회영양학회지
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• 제1권2호
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• pp.260-268
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• 1996

This study aimed to develop an experimental animal model of duodenal ulcer for application to nutrition, and to verify the nutritional characteristics. The 7 different doses and 8 different injections of cysteamine and 2 kinds of diets with different casein levels(10%, 20%) were tested to examine the incidence and the process of duodenal ulcer in female Sprague-Dawley rats. The result showed that the duodenal ulcer was induced when rats fed 10% casein diet(for 9 days) were injected 6 times with 13mg/100g BW cysteamine. The first injection was conducted after 24 hours of fasting, followed by the 2nd shot after 3 hours. The following shots were repeated every 3 day(4th and 7th days). Duodenal ulcer was observed 3 days after the last injection by optical microscope and the naked eye. The characteristics of nitrogen bioavailability of duodenal ulcer model were as followings : 1) gastric emptying rate was faster, 2) trypsin activity at duodenum was higher, 3) total protein concentration at serum and nitrogen retention rate were lower than the control. (Korean J Community Nutrition 1(2) : 260-268, 1996)

• 한국식품영양과학회지
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• 제22권4호
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• pp.374-380
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• 1993

녹차추출액을 사용하여 Sprague Dawley 휜쥐를 63일간 사육한 뒤 십이지장궤양 유발제 cysteamineㆍHCI(400mg/1kg b.w.)을 투여하면 수도물에 의해 같은 기간 사육한 대조군 (TW군) 보다 cysteamine에 대한 감수성은 유의하게 저하되어 십이지장궤양 발병율이 TW군의 50%를 나타냈다. 또한 TW군은 cysteamine투여에 의해 십이지장점막 극재 효소인 alkaline phosphatase (ALP) 활성을 상부십이지장 점막에 있어서 현저하게 저하시켰으나 GT군은 유의하게 활성이 유지되고 ALP 분자종에 있어서도 TW군과 상이한 양상을 나타내 녹차 추출액이 cysteamine 궤양에 있어서 항 궤양적 생리활성을 발휘하고 있는 사실이 밝혀졌다.