• 한국유기농업학회지
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• 제6권2호
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• pp.117-125
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• 1998

For isolation of antagonistic fungi antagonistic to Phytophthora capsici, a total of 157 isolates of fungi were screened from soil. Among the 157 isolates further screened by the dual culture test on potato dextrose agar and V-8 juice agar, 16 isolates were tested to show their antagonistic activity against P. capsici and Fusarium oxysporum. Fungal cul-ture filtrates of screened 16 isolates were shown to inhibit germination of zoospoorangia of P. capsici entirely and conidia of F. oxysporum considerably. Antagonistic fungi were shown to suppress of P. capsici infection of red-pepper plants maintained in the green house. Four isolates. 27 J5, 37 J10, 36 J13 and 31 K10, with the reduced disease incidence 53.3∼60.0% were identified as Fusarium sp. (27 J5). Trichoderma sp. (37 J10, 36 J13) and Penicillium sp. (31 K10).

• Journal of Preventive Medicine and Public Health
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• 제41권4호
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• pp.214-218
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• 2008

Bioterrorism events have worldwide impacts, not only in terms of security and public health policy, but also in other related sectors. Many countries, including Korea, have set up new administrative and operational structures and adapted their preparedness and response plans in order to deal with new kinds of threats. Korea has dual surveillance systems for the early detection of bioterrorism. The first is syndromic surveillance that typically monitors non-specific clinical information that may indicate possible bioterrorism-associated diseases before specific diagnoses are made. The other is infectious disease specialist network that diagnoses and responds to specific illnesses caused by intentional release of biologic agents. Infectious disease physicians, clinical microbiologists, and infection control professionals play critical and complementary roles in these networks. Infectious disease specialists should develop practical and realistic response plans for their institutions in partnership with local and state health departments, in preparation for a real or suspected bioterrorism attack.

• Clinical and Experimental Pediatrics
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• 제59권sup1호
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• pp.80-83
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• 2016

Isolated anomalous right coronary artery originating from the pulmonary artery (ARCAPA) is a rare congenital coronary anomaly that is asymptomatic and discovered incidentally in most cases. ARCAPA is generally not considered a fatal defect in infancy or childhood, although cases of sudden death have been reported. Here, we report a 2-month-old female infant who presented with a prolonged fever that was determined to be caused by rhinovirus infection. Myocardial ischemia of the left ventricular posterior wall was already seen on echocardiography, and ARCAPA was discovered incidentally. The patient underwent successful surgical reimplantation of the right coronary artery to the aortic root to re-establish dual ostial circulation.

• Journal of Microbiology and Biotechnology
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• 제5권6호
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• pp.346-352
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• 1995

For isolation of antibiotic-producing bacteria antagonistic to Fusarium oxysporum, a total of 327 microorganisms were screened from sesame-growing soils collected at various locations in Korea by the modified Herr's triple-agar-Iayer technique. Among the 36 bacterial isolates further screened by the dual culture test on tryptic soy agar, 10 were tested to show their antagonistic activity against 14 plant pathogenic fungi. Bacterial culture filtrates were shown either to inhibit some phytopathogenic fungal growth or to suppress F. oxysporum infection of sesame plants maintained in the green house. An isolate, B23, with the most prominent antagonistic activity was identified as Bacillus subtilis.

• 한국수의병리학회:학술대회논문집
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• 한국수의병리학회 2004년도 추계 학술대회 초록집
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• pp.40-40
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• 2004

• Journal of Microbiology
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• 제43권5호
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• pp.437-442
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• 2005

Sera from rabbits were infected with Vibrio vulnificus containing an antibody against major outer membrane protein (MOMP). MOMP of V. vulnificus ATCC 27562 were isolated and purified by Sarkosyl and TritonX-100 dual treatment. Molecular size of MOMP was identified as 36-kDa on $13\%$ SDS-PAGE. The sequence of the first 26 amino acid residues from the N-terminal end of the protein is AELYNQDGTSLDMGGRAEARLSMKDG, which is a perfect match with OmpU of V. vulnificus CMCP6 and YJ016. MOMP specific IgM and IgG were investigated in groups of mice. The group of mice immunized with MOMP and Alum showed higher levels of IgG2b than the group immunized with only MOMP. Vaccination with MOMP resulted in protective antibodies in the mouse infection experiment.

• 미생물학회지
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• 제18권4호
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• pp.172-179
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• 1980

The rhizome rot of ginger, caused by fusarium oxysporum f.zingiberi, gives a great deal of damages to the ginger farming in Korea. Main symptoms to the disease include the yellowing and blighting of the stems as the rotting of rhizomes. The infection rate was 20 percent in Bongdong, Jeonbug, whereas 10 percent in Susan, Chungnam. The rate was higher at the farm where gingers had been cultivated for many years. To control the disease, soil fungicides Dowfum MC-2 and Tolene C-17 were turned out to be more effective than Di-Trapex nad Daconil. Treatment of Benlate to the rhizome pieces, which were cut for propagation, also showed a better result as compared with that of Othocide. Dual treatment of both Dowfum MC-2 or Tolene C-17 to the farm soil and Benlate to the rhizome pieces was recommended for the best chemical control.

• Archives of Plastic Surgery
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• 제46권1호
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• pp.88-91
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• 2019

The burn center in our hospital is a national and regional (Southeast Asia) center. Of all admissions, 10% are related to blast explosions, and 8% due to chemical burns. In the acute burn management protocol of Singapore General Hospital, early surgical debridement is advocated for all acute partial-thickness burns. The aim of early surgical debridement is to remove all debris and unhealthy tissue, preventing wound infection and thereby expediting wound healing. In chemical burns, there can be stubborn eschars that are resistant to traditional debridement. We would like to present a novel technique using the diathermy scratch pad as a cheap and efficient tool for the dual purpose of surgical debridement and dermabrasion.

• The Plant Pathology Journal
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• 제33권6호
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• pp.608-613
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• 2017

The full-length sequence of a new isolate of Apple chlorotic leaf spot virus (ACLSV) from Korea was divergent, but most closely related to the Japanese isolate A4, at 84% nucleotide identity. The full-length cDNA of the Korean isolate of ACLSV was cloned into a binary vector downstream of the bacteriophage T7 RNA promoter and the Cauliflower mosaic virus 35S promoter. Chenopodium quinoa was successfully infected using in vitro transcripts synthesized using the T7 promoter, detected at 20 days post inoculation (dpi), but did not produce obvious symptoms. Nicotiana occidentalis and C. quinoa were inoculated through agroinfiltration. At 32 dpi the infection rate was evaluated; no C. quinoa plants were infected by agroinfiltration, but infection of N. occidentalis was obtained.

• Biomolecules & Therapeutics
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• 제20권5호
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• pp.433-445
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• 2012

During the course of evolution, animals encountered the harmful effects of fungi, which are strong pathogens. Therefore, they have developed powerful mechanisms to protect themselves against these fungal invaders. ${\beta}$-Glucans are glucose polymers of a linear ${\beta}$(1,3)-glucan backbone with ${\beta}$(1,6)-linked side chains. The immunostimulatory and antitumor activities of ${\beta}$-glucans have been reported; however, their mechanisms have only begun to be elucidated. Fungal and particulate ${\beta}$-glucans, despite their large size, can be taken up by the M cells of Peyer's patches, and interact with macrophages or dendritic cells (DCs) and activate systemic immune responses to overcome the fungal infection. The sampled ${\beta}$-glucans function as pathogen-associated molecular patterns (PAMPs) and are recognized by pattern recognition receptors (PRRs) on innate immune cells. Dectin-1 receptor systems have been incorporated as the PRRs of ${\beta}$-glucans in the innate immune cells of higher animal systems, which function on the front line against fungal infection, and have been exploited in cancer treatments to enhance systemic immune function. Dectin-1 on macrophages and DCs performs dual functions: internalization of ${\beta}$-glucan-containing particles and transmittance of its signals into the nucleus. This review will depict in detail how the physicochemical nature of ${\beta}$-glucan contributes to its immunostimulating effect in hosts and the potential uses of ${\beta}$-glucan by elucidating the dectin-1 signal transduction pathway. The elucidation of ${\beta}$-glucan and its signaling pathway will undoubtedly open a new research area on its potential therapeutic applications, including as immunostimulants for antifungal and anti-cancer regimens.