• 대한한방내과학회지
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• 제16권1호
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• pp.40-61
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• 1995

This study was performed to investigate concept, systoms, causes of disease, pathogenic mechanisms, therapies and precriptions about senile constipation through the successive medical literature, recent chinese medical literature and chinese medical joumals. Senile constipation seems to be applicable to dryness syndrom and constipation of insufficiency type, have something to do with kidney(the most), lung, spleen and large intestine. The most principal cause of disease is yin-fluid, the rest deficiency of qi, insufficiency of yang, stagnation of qi and retention of fever etc. There are enriching the blood and moistening dryness in principal therapy, the rest are invigorating qi and loosing the bowel, warming and invigorating the spleen and kidney, regulating the flow of qi and promoting the stagnancy of qi and expelling the pathogenic heat etc. In prescriptions there are Yunjangtang, Jengaektang, Hwanggitang, Jechunjeon, Yukmatang and Majainhwan as the causes of disease, meanwhile are Yungjang-tang, Jechunjeon and Majainhwan in the vulgaris prescriptions. And in medical herbs there are nourishing yin medicines as Rhizoma rehmanniac, Radix ophiopogonis and Radix scrophulariae etc., invigorating qi medicines as Radix astragali, Radix codonopsitis and Radix polygoni multiflori etc, invigorating yang medicines as Caulis cistanchis and Semen psoraleae etc., promoting qi circulating medicines as Radix saussurea, Lignum aquilariae and Radix linderae etc., and reducing fever and therapeutic method to keep the adverse qi flowing downward medicines as Semen cannabis, Rhizoma rhei, Fructus immaturus ponciri, and Cortex magnoliae etc.. Meantime Rhizoma rehmanniae, Radix ophiopogonis, Caulis cistanchis, Radix angelicae gigantis, Semen cannabis, Semen biotae, Semen pruni japonicae and Semen persicae in principal herb-medicines. In clinical reports the process of disease was between 10 to 20 years, the evacuation cycle between 4 to 7 days, generally possessed chronic diseases as hypertension, diabetes, arteriosclerosis and cerebro- vascular disorders etc. and the efficiency rate was more than 90%. The senile constipation is occured in succession or promoted by chronic diseases as obesity, hypertension, diabetes, arteriosclerosis. hrperlipemia, cerebro- vascular disorders etc., so diet-regulating, adequate exercise, proper evacuation-habit and psychologic rest etc. are important more than medicine-treatments.

• 동의생리병리학회지
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• 제26권3호
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• pp.265-272
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• 2012

The applicability of Diabetes Mellitus(DM) in Oriental Medicine might be placed under the category in Wasting-thirst(消渴, WT). However, because of WT having so various concepts, classification, and names in Oriental Medicine, this resulted in confusion in applying WT treatment to DM. WT occurs mainly due to dryness-heat(燥熱) which by depleting 'Fluid and Humor'(津液) makes symptoms of thirst(口渴) swift digestion with rapid hungering(消穀善饑) frequent urination(小便頻數) according to the "Internal Classic"(內經). WT was also called Sodan(消癉), Bidan(脾癉), or Sojoong(消中) in the "Internal Classic", which was caused by not only the disorder of 'five viscera' (五臟), but also the failure of 'three yin and three yang'(三陰三陽). However, the doctors of those days had a tendency to manage WT (including DM) with herbal drugs of dryness-heat or with drugs that recover the pancreas and the kidney, that have a tendency to appreciate that WT is the disease of 'five viscera'(五臟). Accoding to the "Internal Classic"(內經) and "Jinguiyaolue"(金匱要略), WT was appreciated that WT is also due to the disorder of Meridian including 'three yin and three yang'(三陰三陽) theory. Disorder of 'yang brightness'(陽明) or 'reverting yin'(厥陰) would cause Wasting-thirst(消渴), so the 'three yin and three yang'(三陰三陽) theory should be considered in WT treatments. Furthermore, 'yang brightness'(陽明) and 'reverting yin'(厥陰) all belong to 'the door'(闔) in the bolt-door-pivot(關闔樞) theory, and the mean of 'the door'(闔) is the function of storage, so we could understood WT is the wasting disease due to the disorder of 'the door'(闔) system in Meridian. WT should also be understood by the point of the bolt-door-pivot(關闔樞) theory in addition to the 'three yin and three yang'(三陰三陽) theory.

• Journal of Yeungnam Medical Science
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• 제24권2호
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• pp.305-310
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• 2007

수술 후 인후 합병증은 통증이나 구토에 비하면 사소한 합병증이지만 흔히 환자들이 불편을 호소한다. 양 측 내시경적 부비동 수술 후에 양 코를 막아 입으로 숨 쉬게 되어 구강 건조가 더 심할 것으로 보고 환자들을 glycopyrrolate를 전투약 하고 반전시에 쓴 경우, 전투약 하지 않고 반전에만 쓴 경우, 전투약에만 쓰고 반전은 atropine을 쓴 경우, 전투약 하지 않고 반전은 atropine으로 한 경우의 네 군으로 나누었다. 마취 종료 1시간, 6시간, 12시간, 24시간, 48시간 후의 인후통과 쉰 소리 여부를 묻고, 없는 경우 0, 있는 경우에는 감기 시 목 아픈 것 보다 약하면 1, 비슷하면 2, 더 심하면 3으로 하여 심각도를 나누어 물었다. 각 군 간의 인후통 발생률은 1군에서 조금 높았으나 유의한 차이가 없었다. 심각도는 모두 1이하로 낮았다. 쉰 소리는 모든 환자에서 발생하지 않았다. 양측 내시경적 부비동 수술 후 인후 합병증은 심각도가 낮고 24시간 내에 사라지는 것으로 항콜린성 제제 사용을 피해야 할 필요성은 없을 것으로 보인다.

• 대한한의학회지
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• 제25권1호
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• pp.129-141
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• 2004

Objective: The purpose of this clinical observation was to estimate the efficacy of Quetong & Voice on the abatement of subjective symptoms related nose & pharynx. Methods: We observed 46 patients who visited Kang-Nam oriental hospital with subjective symptoms related nose & pharynx that were prescribed Quetong or Voice. We made an inquiry into the inconvenience, side effect, abatement of subjective symptoms, etc. We used the Wilcoxon signed rank test. Results and Conclusions: 1. The distribution of age & sex was as fallows: 21-30 years(34.8%) were the most, 31-40 years(26.1 %) were the second, 1-10 years(24.0%) were the third. Total patient numbers for men and women were 15 men(32.6%), 31 women(67.4%). 2. The distribution of prescribed aerosols for 46 patients: 5 cases(10.9%) prescribed Quetong, 22 cases(47.9%) prescribed Voice, and 19 cases(41.3%) prescribed Quetong & Voice. 3. The duration of use: 12 cases(26.1 %) used 1 week, 19 cases(41.3%) used 1-2 weeks, 9 cases(19.6%) used 2-4 weeks, 4 cases(8.7%) used 4-8 weeks, and 2 cases(4.3%) used above 8 weeks. 4. The frequency of use: The most patients used 1-5 times(69.6%) or 5-10 times(21.7%) for a day. 5. Quetong & Voice were effective on abatement of subjective symptoms(rhinorrhea, nasal obstruction, pharyngalgia, sneeze or cough, post nasal drip, pharyngeal pruritus, pharyngeal dryness, nasal dryness, and globus hystericus). 6. We must prescribe Quetong to the child or the sensitive patients with discretion becouse of the sting. 7. The side effect was not occurred in all of 46 patients.

• 한국수자원학회논문집
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• 제41권2호
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• pp.173-184
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• 2008

본 연구에서는 기후학적 물수지 방법을 실제 유역에 적용하여 유역 상황을 모니터링하는 방법으로 구축하였다. 이 기후학적 물수지로부터 생성되는 과잉수분량은 유역에서의 지표면 유출 성분을 반영하여 홍수유출의 유추, 치수 구조물의 설치 및 운영에 관한 지표로 활용할 수 있으며, 부족수분량은 가뭄에 대한 정보를 취득할 수 있음을 알 수 있었다. 특히 이러한 두 가지 지표를 합성하여 얻어지는 습윤지표는 유역의 습윤상황뿐만 아니라 건조상황까지도 고려할 수 있으며, 이로부터 2001년 실제 가뭄현상에 대한 분석을 실시한 결과 이 습윤지표가 실제 현상을 잘 반영하고 있음을 알 수 있었다. 본 연구에서는 유역의 습윤 및 건조상황 감시를 위하여 NOAA/AVHRR자료에 근거한 증발산량 산정결과를 토대로 지표면의 건습을 평가하였으며, 이러한 위성자료의 이용이 가뭄이 되풀이 되고 있는 우리나라에서 가뭄의 조기경보를 위해 효과적인 도구로서 이용될 수 있음을 확인하였다.

• 한국치위생학회지
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• 제13권2호
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• pp.231-237
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• 2013

Objectives : The purpose of this study to provide preliminary data to effective halitosis control. Methods : A survey was carried out the self-perception of causative factors of halitosis in 98 female college students in Chungnam province. In addition, the levels of oral gas and breath gas were measured by use of the B&B checker, and an analysis was made of the correlation between halitosis and obsessive-compulsive disorder (OCD). Results : 1. Subjective halitosis awareness degree different degree of dryness, 'None', 'some', 'little' people who feel as the 'little fly' (68%), 78.3%, 70% was higher (p<0.05), halitosis interest 'very worried', 'worry', 'normal' person with a' not at all 'to 58.3% higher (p<0.01). 2. In regard to OCD severity, 49.0%, 34.7% and 16.3% were found to be mild, moderate and severe respectively. Halitosis tended to be severe in proportion to OCD severity, which was statistically significant (p<0.05). 3. Oral gas had a positively correlation with breath gas (r=0.329, p<0.01), but had a negative one with OCD severity (r=0.204, p<0.05). Conclusions : Symptoms of oral dryness and halitosis interest were associated with self-perception of halitosis. The levels of oral gas and breath gas were in inverse proportion to OCD severity. Hereat, it needs to analyze psychogenic factors properly as regards the diagnosis or treatment of halitosis.

• 미생물학회지
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• 제39권3호
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• pp.197-200
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• 2003

기존의 핵산증폭기를 사용하여 유리 슬라이드상에서의 효과적인 원위치 중합효소 연쇄반응(in situ PCR)을 수행하기 위해서는 여러 가지 조건들을 고려해야 하는데, 이러한 조건에는 PCR 용액의 세포속으로의 침투, 증폭된 PCR산물의 세포외 유출의 방지, PCR용 액 성분의 유리슬라이드로의 비특이적 부착으로 인한 손실, 열에 의한 시약의 증발, heat block으로부터 슬라이드로의 열전도성 둥이 있다. 특히 PCR용액 성분의 세포내로의 침투를 보장하기 위해서는 다소 높은 농도의 PCR 용액성분(특히 4.5 mM $MgCl_{2}$ 농도)이 필요하였고, Taq 효소는 PCR전 처리(pre-PCR incubation)를 수행하는 경우,50 ${\mu}l$ 반응당 5～10 units이면 충분하였다. 또한 PCR의 전형적인 온도-시간 양상(temperature-time profile)을 만족시키기 위해서는 먼저 샘플의 건조화를 방지해야 하는데, 이를 위해서 heat block속의 빈 공간에 적당량의 물을 첨가했고, 설정온도와 실제온도를 측정해본 결과 약3～$4^{\circ}C$의 차이가 있었다.

• 한국식품저장유통학회:학술대회논문집
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• 한국식품저장유통학회 2003년도 제23차 추계총회 및 국제학술심포지움
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• pp.218.3-219
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• 2003

백편을 만들 때 멥쌀가루 100에 찹쌀가루를 총중량의 0%, 5%, 10%, 15%, 20%, 25%, 30% 첨가하고 저장시간 0시간, 24시간, 48시간, 72시간 저장한 후 (4$^{\circ}C$에서) reheating 한 백편의 기호성과 조직감(Texture)에 어떠한 영향을 끼치는 가를 관능검사와 기계적 검사에 의해 측정한 결과를 다음과 같이 요약할 수 있다 1. 관능검사 결과 백편의 Color 는 찹쌀의 첨가량이 증가할수록 누런색이 짙어졌으며, 24, 48, 72 시간 저장한 후 reheating 한 백편도 누런색이 짙어지는 경향을 나타냈다. Coarseness 는 찹쌀의 첨가량이 증가할수록 증가하는 경향이었으나 저장전의 백편은 유의적인 경향을 나타내지 않았다. 찹쌀의 첨가량이 증가할수록 Softness, Dryness, crumblyness는 감소경향을 나타냈으며 24, 48, 72 시간을 저장한 후 reheating 한 백편도 유의적인 감소경향을 나타냈다. 외관의 기호도는 찹쌀의 첨가율이 5% 인 백편을 가장 좋아했고, 조직감 및 종합적인 기호도는 찹쌀의 첨가율이 10~20%인 백편을 좋아했다. 2. Rhemeter에 의한 백편의 Texture는 찹쌀의 첨가량이 증가할수록 Compression force, gumminess, Chewiness가 증가하는 경향을 나타냈다. 24, 48, 72 시간 저장한 후 reheating 한 백편은 저장전보다 점점 감소경향을 나타냈다가 72시간 저장한 후 reheating 하면 다시 증가경향을 나타냈다. Work ratio 및 Recovered height는 찹쌀의 첨가량과 저장시간의 변화에 크게 영향을 미치지 않았다. Recovered 하지 않고 0, 24, 48, 72 시간 저장한 백편의 Compressing force는 찹쌀의 첨가량이 증가할수록 증가경향이 컸고 저장시간이 경과함에 따라 Compression force가 증가하였는데 특히 24시간 저장하는 동안 급격히 증가하였다. 3. 찹쌀 첨가량이 증가할수록 수분함량은 증가하였고, 저장시간이 경과함에 따라 수분함량은 감소경향을 나타냈으나 24시간 저장한 후 reheating 한 백편만이 수분함량의 증가경향을 나타내었다. 4. qoruvs의 Softness 는 Compression force 및 Work ratio 와 유의적인 상관관계를 나타내었으며, Dryness 와 Crumblyness 는 Work ratio와 유의적인 상관관계를 나타내고 있어 백편의 조직감은 Compression force 와 Work ratio로 대치할 수 있을 것이라고 사료된다. 수분함량은 기계적 검사보다 관능검사와 더욱 높은 상관관계를 나타냈다.

• 한국간호교육학회지
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• 제10권1호
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• pp.149-160
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• 2004

The primary purpose of this study was to describe psychological aspects of menopausal women who have experiences on alternative therapies, such as pomegranate tree fluid, life pack, evening primerose, zacro syrup, zacro pill, multi-vitamin, oriental medicine instead of estrogen. In order to have insights on the participants behaviors, this qualitative research was conducted. The participants in this study were six women who have been taking at least one of the alternative therapies to relieve the menopausal symptom. Data had been collected from November 2002 to May 2003. The interview questions were about motivations to seek the alternative therapy, menopausal symptoms, feelings or positive effects after the treatment. The interviews were recorded and transcribed into written documents. The method described by Giorgi was utilized for data analysis. The study results were as follows : 1. The participants sought the alternative therapy based on their own information or by friends' recommendations. The motivations of taking the therapy were to live younger and healthier by reliving menopausal symptoms including somatic symptoms, such as irregular menstruation, flushing sense, cold sweating, insomnia, dull headache, vagina dryness, cystitis after sexual intercourse, joint pain, nervousness, depression, skin dryness, and suppression of activity. 2. The participants expressed that they became more active and felt better with disappearing menopausal symptoms after about 2 to 3 weeks treatment. 3. The participants did not want to accept the fact that they had menopause, which caused avoidance of having medical diagnosis and medical treatment. They also did not want to let their spouses know about their symptoms. 4. The major reason of taking the alternative therapy was to avoid the side effects of estrogen therapy in spite of high costs of the alternative way. 5. The participants suggested that menopausal women needed to be educated about physical and psychological symptoms of menopause. They also needed to be informed about how to manage it. In conclusion, accurate information about foods and drugs utilized for the alternative therapy was needed. Medically proved methods to recognize positive effects and side effects were also necessary. These goals could be achieved by continuous medical observations and further research.

• 한방안이비인후피부과학회지
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• 제22권1호
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• pp.120-132
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• 2009

Objective : Yukmijihwang-tang is one of the important medicines for blood- deficiency and yin-deficiency. Atopic dermatitis usually shows dampness-heat pattern in its acute stage and blood-deficiency or yin-deficiency pattern in its chronic stage. Therefore, I hypothesized that Yukmijihwang-tang is effective on atopic dermatitis and investigated the effects of Yukmijihwang-tang on NC/Nga mice's atopic dermatitis induced by DNCB. Methods : The NC/Nga mice with atopic dermatitis were divided into four groups: three experimental groups and one control group. The experimental groups were respectively put on 2.5g(YM-2.5), 5g(YM-5) and 10g(YM-10) of Yukmijihwang-tang extract per their weight once a day for 10 days while the control group was fed normal saline. After 10 days, I measured TEWL(transepidermal water loss), observed scratching behaviors, conducted a skin biopsy and checked levels of Total IgE, IL-4 and $IFN-\gamma$ on NC/Nga mice. Results : 1. Yukmijihwang-tang significantly suppressed skin dryness. In particular, YM-5 and YM-10 had better skin hydration than YM-2.5. 2. Yukmijihwang-tang significantly suppressed pruritus while there was no significant difference among the experimental groups. 3. Yukmijihwang-tang retained skin structure(epidermis, dermis and subcutaneous fat). 4. Yukmijihwang-tang reduced Total IgE level while there was no significant difference between the control group and the experimental groups. 5. Yukmijihwang-tang did not reduce IL-4(Th2 cytokine) level. 6. Yukmijihwang-tang significantly reduced $IFN-\gamma$(Th1 cytokine) level. In particular, YM-2.5 and YM-5 had lower $IFN-\gamma$ level than YM-10. Conclusion : The results suggest that Yukmijihwang-tang suppresses skin dryness and pruritus, retains skin structure and is effective on chronic atopic dermatitis which is associated with Th1 cytokines in the immune response.