• 제목/요약/키워드: drop-out

검색결과 1,049건 처리시간 0.027초

함정 격실기밀 평가 방안에 대한 신뢰성 향상 연구 (A Study on the Reliability Improvement of Compartment Leak Test in Surface Vessels)

  • 최상민;박동규;백용관
    • 한국산학기술학회논문지
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    • 제21권4호
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    • pp.546-551
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    • 2020
  • 함정에는 격벽으로 구분되어 나누어지는 공간인 격실이 종류와 목적에 따라 수개 혹은 수십 개가 존재한다. 이러한 격실들은 화재 및 화재로 인한 연기의 전이방지, 침수 시 침수의 확산 방지 등 특정 격실에서 발생하는 특이 상황들이 타 격실로의 전이를 방지하여 생존성 향상에 목적을 두고 설계된다. 생존성 향상 목적 달성을 위하여 각 격실들은 기밀 또는 수밀을 유지하도록 건조하며, 각 격실의 기밀 또는 수밀 정도를 확인하기 위하여 함정 건조 단계에서 평가를 수행한다. 건조하고 있는 군함에 관한 평가는 해군 지침에 의거하여 함 건조업체 주관으로 해군 및 국방기술품질원이 입회하여 평가를 실시한다. 생존성과 직결되는 만큼 격실 기밀 평가의 중요성은 매우 높아 명확한 기준에 따라 수행되고 있으나, 1개 이상의 복수개 격실 기밀 평가 시 1개 압력센서로 압력을 측정하여 격실 압력을 실시간으로 확인하는 것과 각 격실별 미세한 압력 변동 사항 확인이 제한되는 것을 식별하였다. 따라서 본 연구에서는 현재 수상함정 중 군함에서 실시하고 있는 그룹 격실 기밀평가 방안에 대한 개선 방안 및 신뢰성 검증 방안에 대해 서술하였다.

가감생혈윤부음(加減生血潤膚飮)의 당뇨병 치료효과 확인을 위한 생리활성성분 분석과 경구포도당부하 연구 (Studies about the bioactive component analysis and an oral glucose tolerance test of Add-Omit-Saenghyeoryunbu-eum(AO-SHU) for confirmation of diabetes therapy)

  • 인정도;임대식;김원일
    • 대한한의학방제학회지
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    • 제24권2호
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    • pp.80-99
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    • 2016
  • Objectives : Instrumental chemical analysis was utilized to investigate the effect of Add-Omit-Saenghyeoryunbu-eum(AO-SHU) on diabetic treatment. One of the most exciting, yet also controversial, arguments is the safety and biological mechanisms of the natural medicine on human body. Therefore, the aim of this study is to provide a better understanding on bioactive chemical components, hazards of heavy metal contamination and biological mechanism of the diabetic medicine composed of 12 different natural herbs. Methods : To study bioactive compound and metallic component in the diabetic medicine in detail, LC-MS/MS (Liquid Chromatography-Mass/Mass), GC (Gas Chromatography) and ICP (Inductively Coupled Plasma) were utilized to characterize the extract of the diabetic medicine and the result was compared with 18 marker substances selected from literature survey. In addition, in vitro assay experiments including GPR 119 activity and human DGAT-1 inhibition, and OGTT (Oral Glucose Tolerance Test) were performed to verify the effectiveness of this medicine on diabetic treatment. Results : Out of 18 marker substances, 9 bioactive compounds were identified from LC-MS/MS analysis which include Citruline, Catalpol, Berberine, Ginsenoside Rb1, Ginsenoside Rg1, Oleanolic acid, β-Sitosterol, Mangiferin, and Schizandrin. ICP study on 245 residual pesticides revealed that 239 species were not detected but 6 species, Dimethomorph, Trifloxystrobin, Pyraclostrobin, Isoprocarb, Carbaryl and Flubendiamide, while the amounts are trace levels, below permitted concentrations. The biological activity was observed in vitro assay and Oral Glucose Tolerance Test(OGTT), which are consistent with a preliminary clinical test result, a drop in blood sugar level after taking this herbal medicine. Conclusions : Instrumental chemical analysis using LC-MS/MS, GC, and ICP was conducted successfully to identify bioactive compounds in AO-SHU for the treatment of diabetes, finding 9 bioactive compounds. Furthermore, in vitro assay experiments and OGTT show that AO-SHU has its biological activities, which imply that it can be a candidate for the future diabetes remedy.

전산 해석에 의한 파풍망의 설치 효과와 최적 파이프 규격 (The Installation Effect and Optimal Pipe Sizes of an Anti-Wind Net by Computational Analysis)

  • 염성현;권기정;성시흥;최영돈
    • Journal of Biosystems Engineering
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    • 제32권6호
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    • pp.430-439
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    • 2007
  • This study was carried out to(1) visualize the installation effect of an anti-wind net; (2) evaluate structural stability of typical anti-wind nets in Jeju; and (3) present the optimal specification of pipes in an anti-wind net for maximum instant wind velocities of 40 m/s and 45 m/s. The analyses were done for anti-wind nets with a mesh of 4 mm and a height of 3 m by using CFX and ANSYS. The results showed that the wind went down due to flow resistance when passing through an. anti-wind net. The anti-wind net with the supporting pipe being installed every two main columns was certainly unstable because the main column not sustained by the supporting pipe became cantilever. With regard to the position of a fixing point of the supporting pipe, von Mises stress on pipes was certainly increased as vertical positions of the supporting pipe were changed to be too lower or higher than an adequate position but there was little difference according to horizontal positions. The adequate vertical position was $2{\sim}2.5\;m$ high from the ground. For a maximum instant wind velocity of 40 m/s, the optimal specification of pipes was a main column of ${\varphi}48.1{\times}2.1$ t@2,000, cross beams(bottom and top) of ${\varphi}26.7{\times}1.9\;t$, cross beams(center) of ${\varphi}33.5{\times}2.1$ t/2ea and a supporting pipe of ${\varphi}31.8{\times}1.5$ t@2,000. In case of a maximum instant wind velocity of 45 m/s, the optimal specification of pipes with structural stability was a main column of ${\varphi}48.6{\times}3.25$ t@2,000, cross beams(bottom and top) of ${\varphi}26.7{\times}1.9\;t$, cross beams(center) of ${\varphi}48.1{\times}2.1$ t/2ea and a supporting pipe of ${\varphi}31.8{\times}1.5$ t@2,000.

항장요법(肛腸療法)에의한 진간식풍탕(鎭肝熄風湯)이 CHT로 유발된 백서(白鼠)의 뇌부종 및 신경 장애에 미치는 영향 (The Effects of Jingansikpung-tang, derived from Anal Therapy on CHT-induced Brian Edema and Neurological Disturbance Symptom in Rats)

  • 문석재;문구;원진희;유경태;문영호;이종범;김홍준;이종덕;윤준철
    • 대한한방내과학회지
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    • 제23권1호
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    • pp.47-56
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    • 2002
  • Objectives: We identified the effects of Jingansikpung-tang, (JGSPT), derived from therapy on closed head trama(CHT)-induced brain edema and neurologial disturbance symptom in rats. Methods : We used a drop device and induced CHT. We divided the animals into 3 groups. They were JGSPT 1 group (Administered JGSPT 96.5mg/kr through anal far one hour after using CHT) and JGSPT 2 group(Administered JGSPT 386mg/kg through anal for one hour after using CHT) Then, we tested neurological severity score(NSS), water content of brain and haematological changes. Result : aNSS increased significantly in JGSPT 1 and JGSPT 2 as compared to the controlled group, and the change of water content which was pulled out of the right hemisphere from the left hemisphere decreased in JGSPT 1 and JGSPT 2 as compared to the controlled group. The lactate level in serum decreased in JGSPT 1 and JGSPT 2 as compared to the controlled group, which showed no efficacy. Glucose level in serum increased in JGSPT 1 and JGSPT 2 as compared to the controlled group, only JGSPT 2 showed no efficacy. Conclusions : JGSPT, caused by Anal Therapy and effect on CHT-induced brain edema and neurological symptom.

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두경부암에서 저용량 Cisplatin 기반 매주 요법의 항암방사선 동시치료의 독성과 예비 임상 결과 (The Toxicity and Preliminary Clinical Outcomes of Low-Dose Weekly Cisplatin-Based Concurrent Chemoradiotherapy)

  • 김태용;김경주;김기환;김지은;박선원;오소원;정영호
    • 대한두경부종양학회지
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    • 제27권1호
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    • pp.47-53
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    • 2011
  • Purpose : Concurrent chemoradiotherapy(CCRT) with 3 weekly cisplatin is the standard treatment of locally advanced head and neck cancer(HNC). The aim is to evaluate the efficacy and toxicities of low-dose weekly cisplatin-based CCRT, which was devised to reduce the toxicity of CCRT. Method : We retrospectively analyzed HNC patients who received low-dose weekly cisplatin-based CCRT between 2008 and 2010. Cisplatin 35mg/$m^2$ was weekly given to all patients during radiotherapy. The efficacy was evaluated by the degree of clinical response, treatment failure and survival. The toxicity was evaluated by hematologic toxicities and oral mucositis. Results : A total of 27 patients were analyzed and median age was 59(range 31-81). The ratio of administered dose of radiotherapy and cisplatin to planned dose were 0.98 and 0.93, respectively. Complete remission and partial remission were 73% and 23%, respectively. Treatment failure was observed in 8(30%) patients. 1-year survival rate and 1-year disease free survival rate were 82% and 59%, respectively. Overall survival and progression-free survival did not reach median time. Grade 3/4 anemia, neutropenia, thrombocytopenia and oral mucositis were observed in 11%, 19%, 7% and 32% of patients, respectively. In terms of administered cycles, however, only 1-3% of grade 3/4 hematologic toxicities occurred among total 190 cycles. Severe oral mucositis were statistically associated with old age(p=0.003). Treatment failure had no statistical relation with age, pathology, primary site and stage. Conclusion : Low-dose weekly cisplatin-based CCRT seemed to deliver enough dose of cisplatin and to show low drop-out rate and good efficacy with low hematologic toxicities.

사파중 진동수주형 파력발전장치의 성능평가 (Performance of Oscillating Water Column type Wave Energy Converter in Oblique Waves)

  • 김길원;현범수;홍기용;류진
    • 한국해양환경ㆍ에너지학회지
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    • 제17권3호
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    • pp.182-188
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    • 2014
  • 진동수주형 파력발전시스템의 성능은 OWC챔버의 형상 뿐만 아니라 입사파의 각도와 터빈의 효과로 인한 압력강하등과 같은 작동환경의 영향도 받는다. 기존의 대부분 연구들은 파랑에너지 흡수효율에 초점을 맞췄기 때문에 입사파 방향이 OWC챔버 입구면과 직각을 이룬다는 가정 하에 수행되었다. 하지만 실해역에서는 입사파가 해양환경에 따라 사파의 형태로 입사하게 될 것이고, 고정식 구조물인 경우에는 그 영향이 더욱 지배적이다. 본 논문은 실험 및 수치해석적인 방법으로 사파중 OWC챔버의 성능에 대하여 고찰하였다. 실험은 3차원 조파수조를 이용하여 다양한 입사파 각도조건에서 수행하였다. 터빈의 영향을 고려하기 위하여 오리피스를 적용하여 챔버내 진동수주의 수위 변동을 계측하였다. VOF모델을 기반으로 한 수치조파수조를 구축하여 실험과 동일한 조건으로 계산을 수행하여 실험결과와 비교분석하여 공기실과 그 인근의 유동변화를 고찰하였다.

상변화물질을 충전한 수평원통관 내에서 응고시 열전달특성 (Heat Transfer Characteristics for Inward Solidification in a Horizontal Cylinder Packed with P.C.M.)

  • 염성배;홍창식;이재성
    • 태양에너지
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    • 제11권2호
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    • pp.51-62
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    • 1991
  • 본 연구에서는 용융된 파라핀을 채운 수평 원관의 관벽을 냉각할 때에 관내에서 일어나는 열전달현상을 다루었다. 관내의 파라핀을 고상과 액상으로 구분하여 고상층에 대해서는 열전도 모델을, 그리고 액상층에 대해서는 자연대류를 고려한 열전달모델을 세워 수치해석하였고 이 과정에 대한 실험을 행하여 얻은 응고형태로부터 방열량을 계산하였다. 아울러 초기의 용융파라핀의 온도와 관벽의 냉각온도가 응고에 미치는 영향을 고찰하였다. 방열과정에서 액상파라핀의 응고속도를 결정하는 요인은 관벽의 냉각온도와 초기액상온도이나 대부분의 액상현열이 응고 초기에 급속히 방출되기 때문에 관벽의 냉각온도가 지배적인 요인으로 작용하였다. 따라서 방열과정에서의 열전달은 고상층 내의 열전도에 의해서 이루어지게 된다. 실험에서 관찰한 응고형태에서는 상부에 빈 공간이 발견되었다. 이는 초기 액상온도가 응고초기에 급속히 떨어짐으로써 온도에 따른 액상의 밀도차로 인해 생긴 것이다. 고 액간의 밀도차로 인한 수축현상은 응고과정의 전반에 걸쳐서 고르게 일어나므로 그 영향을 응고형태에서 구별하여 파악하기는 어려웠다. Fourier수와 고상의 Stefan수를 종속변수로 사용하면 관벽의 냉각온도와 초기액상온도에 무관하게 응고량을 단일곡선으로 표현할 수 있었다.

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고아미 2호와 쌀가루 배합 비율을 달리한 설기떡의 품질 특성에 관한 연구 (Study on the Quality Characteristics of Sulgitteok Made with Various Amount of 'Goami 2' and Rice Powder)

  • 정선옥;김현아;이경희
    • 동아시아식생활학회지
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    • 제19권6호
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    • pp.928-934
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    • 2009
  • The purpose of this study was to examine the possibility of making functional sulgitteok with Goami 2 rice, which is a rich that is high in dietary fiber. Sulgitteok was made by adding various amounts of Goami powder(25, 50, 75, and 100 %) to rice powder. Then, the sensory tests and other tests to measure color, texture and hardness were examined as a function of time and the moisture content in sulgitteok was measured to determine the quality and characteristics of different types of sulgitteok. The conclusions of these tests were as follows : In the sensory evaluation preference test of sulgitteok made with various amounts of Goami powder, the overall preference was the highest in sulgitteok made with 50% Goami powder (S2). In the difference test, the higher the amount of added Goami powder, the lower the grades were. The S4 group, which was made with Gomai powder, had a strongly unique odor compared with those made with rice powder, which smelled weaker. In terms of the color values of Gomai added sulgitteok, the higher the amount of added Gomai powder, the lower the lightness value of sulgitteok, where group S4 had the lowest value. In addition, the S4 group, which was made with Goami powder, had the hightest red and yellow color. The texture test indicated that sulgitteok containing a large amount of Goami powder were considerably harder compared with the control group. While every group containing Goami powder (S1, S2, S3 and S4) became harder during the first to the third day of the test, their hardness tended to drop after longer storage times. In the control group, the hardness continued to grow from the start up to the fifth day. After five days' there was a noticeable change in the moisture content in the different types of sulgitteok, with more water evaporating in the S3, S2, and S1 groups than in the S4 groups, which contained the highest amount of Goami powder. Group C, which contained no Goami powder, had the largest water evaporation. Sulgitteok that contained more Goami powder turned out to be more savory than baekseolgi made solely of rice powder. However, they were less preferable overall, since they were rated lower in terms of color, texture and other characteristics. Therefore, utilize Goami tteok as a functional ingredient in food for people with diabetes or obesity, further studies on additives that can provide a sticky texture and favorable color should be conducted. In addition, different types of ttoek such as pounded or boiled ones may be preferable to sulgitteok.

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저출산수준과 강한 남아선호관이 사회에 미치는 영향 -성.연령별 인구 구조의 변화를 중심으로- (The Effects of Fertility and Strong Son Preference on Korean Society - On the basis of the changes of age and sex structure -)

  • 김태헌
    • 한국인구학
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    • 제16권2호
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    • pp.1-23
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    • 1993
  • Korea fertility level has dropped since the 1960's and speed of decline has accelerated in the 1980's. In the resuls, the growth rate reached to less then 1 percent in 1990 and will be $\ulcorner$0 $\lrcorner$ percent growth in 2021. The total population will increase to 50, 586 thousand persons in 2021 then will decrease. With the rapid fertility decline the age structure of Korean population has changed : while the proportion of child population aged 0-14 is decreasing sharply, that of old-age population aged 65 and over is increasing. Because of the recent increase of sex ratio at birth, the sex structure among the young generation has been destorted; the sex ratio at age 0-4 was as high as high as 112.0 in 1990. The effects of these population phenomena on Korean society are the followings: 1) Old age dependency ratio is increasing rapidly and continuously and will be about 40.0 from the 2050's. 2) Because of the rapid decline of the number of births, the absolute number of the major labour force at age 25-34 will decrease after around 2000 and then from the 2010's become less than that in 1990. 3) Since the large fertility defferentials by womens's educational level have continued and the relation between the educational levels of mothers and children are very strong, level has dropped among higher educated women first when the average fertility level has declined in Korea, the average educational level of the children is may be expected to be relatively low and then the future productivity is will be also low, which causes the decline of 'quality of population. 4) When the high sex ratio at birth (over 110 since 1986) continues, number of brides will be short by over 20 percent from the 2010s, which will bring various kinds of social prblems. Therefore, the counter measures in concrete to relieve the heavy problems are recommended as follows: 1) The extention of the birth intervals, which helps to drop the population growth rate at the same level of number of children per women. 2) The positive supports for out-migrants, which helps to reduce the population size without any destortion of age-sex structure. 3) The defferent supports of family planning for the higher and lower classes, which helps to reduce the gaps between different ferility levels of the classes and to keep and improve the quality of population. 4)population education for both students and adults, which helps to minimize the gap between the private and public requirements.

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태양열 이용 축열식 직접접촉 열교환기의 열전달에 관한 연구 (A Study on Heat Transfer of n Storage Type Direct Contact Heat Exchanger for Solar Energy Utilization)

  • 강용혁;전명석;윤환기;천원기
    • 태양에너지
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    • 제15권3호
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    • pp.3-14
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    • 1995
  • 태양열 이용 축열식 직접접촉 열교환기의 실제 적용을 위한 작동조건도출 및 열교환기내 열전달 특성 규명을 위하여 작동유체를 물보다 가벼운 경우(Texaterm)와 무거운 경우 두가지를 실제 태양열 집열회로상에서 실험하였다. 작동유체가 물보다 가벼운 경우와 무거운 경우에 대해 실제 태양열 집열회로상에서 작동하여 최적 열전달을 위한 작동유체드럽형성과 유동을 도출하였고, 작동유체가 무거운 경우가 가벼운 경우보다 열손실계수가 높음을 알 수 있었다. 작동유체가 축열유체보다 가벼운 경우와 무거운 경우에 대해 실제 태양열 직열회로에서 실험한 결과, 작동유체가 가벼운 경우 체적 열전달계수는 $1.848{\times}10^{-3}w/cm^3^{\circ}C$, 효율은 73%이고 무거운 경우는 $0.128{\times}10^{-2}w/cm^3^{\circ}C$, 효율은 82%로 작동유체가 무거운 경우가 보다 좋은 것으로 나타났다.

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