• Journal of the Korean Society of Radiology
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• v.5 no.5
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• pp.223-229
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• 2011

When negative electron in x-ray tube is accelerated in to a high speed and then the currency of the electron is blocked by the target, x-ray happens by the conversion of the energy. The real area where the fast accelerated electron collides to a target area is called actual focal spot. When the string focused size is observed at the central ray side, where the direction x-ray comes out, the size seems to be reduced. This focus is called effective focal spot. According to radiation angle of x-rays tube, the degree of the negative pole side presents higher value than inclination, the amount of exposed radiation that patient receives differs by the angle of positive pole, which means effective focal spot is the variable. This paper presents the correlation between size of effective focal spot and amount of exposed radiation to the patient by it, and effective research for homogenized dose dispersion by the size of effective focal spot. In conclusion, following the focal size, effective range which was -8cm ~ 0 cm on average, was found and average dose rate was 0.019 R/min. Through this range, for patients with small radiation exposure, image with good density and resolution in aspect of diagnosing will be able to be obtained.

• Journal of radiological science and technology
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• v.16 no.1
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• pp.101-106
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• 1993

In order to assure safety of both patient and operator, and to provide uniform quality radiographs, it is necessary to perform periodic calibration of diagnostic X-ray equipment. A basic parameter of diagnostic equipment's and its image sharpness is the size(and shape the energy distribution) of the focal spot as viewed along the central X-ray beam. This size determines the resolution possible with the equipment and also determines the heat characteristics of an anode. A fine focus tube gives high resolution but causes high local heating of target. In past, the pin-hole and star pattern image measurement for evaluation of resolution have been widely used, but it produced blurring and inaccuracy of image. So newly inverted Ug-meter has advantage in more convenient measurement method and less out-put bias than other image measurement. The authors intended to compare measured focal size between Ug-meter and focal spot test tool, changed state from setting to now of units.

• Journal of the Optical Society of Korea
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• v.11 no.2
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• pp.76-81
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• 2007

The compound refractive X-ray lens (CRL) for focusing hard X-rays is investigated to determine the parameters such as the focal length, the focal spot size, and spatial distribution at the focal spot using a simple theoretical calculations and CRLs fabricated by the self-assembly method. The number of individual compound lenses are defined for the given focal length of 1 m. The X-ray energy of 1 to 40 keV is used in the calculations. The CRL for focusing hard X-rays which generated from the X-ray tube is fabricated by nanoparticle-polymer composite in the form of circular concaves. The self-assembly method is applied to form the nanoaluminum-poly (methly meth-acrylate) composite and carbon-polymer composite CRL lenses. Aluminum nanoparticles of 100 nm and carbon microparticles are diffused in the polymer solution then the high gravity up to 6000G is applied in it to form the concave lens shape. X-ray energy at 8 keV is used for characterization of the composite CRLs. The FWHM of intensity for the fabricated nanoaluminium composite CRL system, N=10 is measured as 1.8 mm, which would give about $70{\mu}m$ in FWHM at 1 m of the focal length.

• Journal of the Korean Magnetics Society
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• v.25 no.2
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• pp.52-57
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• 2015

The focal spot of electron beam depending on the anode angle in the structure and major parts of the X-ray tube was investigated by the OPERA-3D/SCALAR simulation program. The simulation worked on four spaces with with two spaces, including anode and cathode of X-ray tube, by applying the finite element method analysis. The analytical model and dimension for the emission orbit of thermal electrons made from one filament of the focused X-ray cathode is affected to the penumbra of detector for the X-ray depending on any real focal spot size. The model shape of focusing cap and focusing tube with an anode target angle and a cathode filament is analyzed by the current density distribution of thermal electrons. The focusing width of thermal electrons for the X-ray tube depended on the anode angle (${\theta}$). The focusing value of electron beams at a region of anode angle having $10^{\circ}{\sim}17^{\circ}$ maintained to below value of $70{\mu}m$. The minimum focal size of the electron beam was $40{\mu}m$ at an anode angle of $15^{\circ}$. The focused X-ray tube of many variables depended on the thermionic emission of hot electrons from the target trajectory. The focusing tube will contribute to the real design of X-ray for the development of future diagnosis medical device.

• Korean Journal of Optics and Photonics
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• v.20 no.6
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• pp.354-360
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• 2009

We have constructed and analyzed the performance of a simple fiber bundle multi-focal microscope. The microscope had a fiber bundle substituted for micro-lens array that is the core part of MMM(multi-focal multi-photon microscope). The MMM is a type of confocal microscope. To analyze the performance and characteristics of the fiber bundle multi-focal microscope, three types of samples were used: a standard grating, USAF 1951(7, 3), and 1951(7, 6). Using two polarizers and a polarizing beam splitter, we eliminated noise and got clear images. We obtained the FWHM of fiber spot images with the standard grating using two different magnifier lenses which were 63X and 20X, and found an image of the sample as a distribution of fiber spot images. For this case we used the low magnification lens, which gives denser distribution, so that we could get clearer images. In order to test the resolution of the fiber bundle multi-focal microscopic system, we used the USAF 1951 sample which has a smaller line interval than that of the standard grating. The FWHM of the line width of the image coincides well with the real line width of the USAF 1951 sample. We confirmed the performance of a fiber bundle multi-focal microscopic system which is relatively simple but has submicron resolution and is able to get 1600 images at the same time.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.17
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• pp.7795-7801
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• 2015

The aim of the present research was to establish primary characteristics of electron beams for a Varian 2100C/D linear accelerator with recently developed PRIMO Monte Carlo software and to verify relations between electron energy and dose distribution. To maintain conformity of simulated and measured dose curves within 1%/1mm, mean energy, Full Width at Half Maximum (FWHM) of energy and focal spot FWHM of initial beam were changed iteratively. Mean and most probable energies were extracted from validated phase spaces and compared with related empirical equation results. To explain the importance of correct estimation of primary energy on a clinical case, computed tomography images of a thorax phantom were imported in PRIMO. Dose distributions and dose volume histogram (DVH) curves were compared between validated and artificial cases with overestimated energy. Initial mean energies were obtained of 6.68, 9.73, 13.2 and 16.4 MeV for 6, 9, 12 and 15 nominal energies, respectively. Energy FWHM reduced with increase in energy. Three mm focal spot FWHM for 9 MeV and 4 mm for other energies made proper matches of simulated and measured profiles. In addition, the maximum difference of calculated mean electrons energy at the phantom surface with empirical equation was 2.2 percent. Finally, clear differences in DVH curves of validated and artificial energy were observed as heterogeneity indexes were 0.15 for 7.21 MeV and 0.25 for 6.68 MeV. The Monte Carlo model presented in PRIMO for Varian 2100 CD was precisely validated. IAEA polynomial equations estimated mean energy more accurately than a known linear one. Small displacement of R50 changed DVH curves and homogeneity indexes. PRIMO is a user-friendly software which has suitable capabilities to calculate dose distribution in water phantoms or computerized tomographic volumes accurately.

• Progress in Medical Physics
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• v.27 no.4
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• pp.272-276
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• 2016

To investigate the optimum x-ray tube design for the dental radiology, factors affecting x-ray beam characteristics such as tungsten target thickness and anode angle were evaluated. Another goal of the study was to addresses the anode heel effect and off-axis spectra for different target angles. MCNPX has been utilized to simulate the diagnostic x-ray tube with the aim of predicting optimum target angle and angular distribution of x-ray intensity around the x-ray target. For simulation of x-ray spectra, MCNPX was run in photon and electron using default values for PHYS:P and PHYS:E cards to enable full electron and photon transport. The x-ray tube consists of an evacuated 1 mm alumina envelope containing a tungsten anode embedded in a copper part. The envelope is encased in lead shield with an opening window. MCNPX simulations were run for x-ray tube potentials of 70 kV. A monoenergetic electron source at the distance of 2 cm from the anode surface was considered. The electron beam diameter was 0.3 mm striking on the focal spot. In this work, the optimum thickness of tungsten target was $3{\mu}m$ for the 70 kV electron potential. To determine the angle with the highest photon intensity per initial electron striking on the target, the x-ray intensity per initial electron was calculated for different tungsten target angles. The optimum anode angle based only on x-ray beam flatness was 35 degree. It should be mentioned that there is a considerable trade-off between anode angle which determines the focal spot size and geometric penumbra. The optimized thickness of a target material was calculated to maximize the x-ray intensity produced from a tungsten target materials for a 70 keV electron energy. Our results also showed that the anode angle has an influencing effect on heel effect and beam intensity across the beam.

• Current Optics and Photonics
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• v.7 no.6
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• pp.701-707
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• 2023

In laser imaging, accurate extraction of the laser's center is essential. Several methods exist to extract the laser's center in an image, such as the geometric mean, the parabolic curve fitting, and the Gaussian curve fitting, etc. The Gaussian curve fitting is the most suitable because it is based on the physical properties of the laser. The width of the Gaussian laser beam depends on the distance from the laser source to the target object. It is assumed in general that the distance remains constant at a laser spot resulting in a symmetric Gaussian model for the laser image. However, on a curved surface of the object, the distance is not constant; The laser beam is narrower on the side closer to the focal point of the laser light and wider on the side closer to the laser source, which causes the distribution of the laser beam to skew. This study presents a modified Gaussian model in the laser imaging to incorporate the slant angle of a curved object. The proposed method is verified with simulation and experiments.

• Journal of Korean Neurosurgical Society
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• v.48 no.5
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• pp.391-398
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• 2010

Objective : This study was designed to validate the cell trafficking efficiency of the in vivo bioluminescence image (BLI) study in the setting of transplantation of the luciferase expressing bone marrow-derived mesenchymal stem cells (BMSC), which were delivered at each different time after transient middle cerebral artery occlusion (MCAO) in a mouse model. Methods : Transplanting donor BMSC were prepared by primary cell culture from transgenic mouse expressing luciferase (LUC). Transient focal infarcts were induced in 4-6-week-old male nude mice. The experiment mice were divided into five groups by the time of MSC transplantation : 1) sham-operation group, 2) 2-h group, 3) 1-day group, 4) 3-day group, and 5) 1-week group. BLI for detection of spatial distribution of transplanted MSC was performed by detecting emitted photons. Migration of the transplanted cells to the infarcted area was confirmed by histological examinations. Differences between groups were evaluated by paired t-test. Results : A focal spot of bioluminescence was observed at the injection site on the next day after transplantation by Signal intensity of bioluminescence. After 4 weeks, the mean signal intensities of 2-h, 1-day, 3-day, and 1-week group were $2.6{\times}10^7{\pm}7.4{\times}10^6$. $6.1{\times}10^6{\pm}1.2{\times}10^6$, $1.7{\times}10^6{\pm}4.4{\times}10^5$, and $8.9{\times}10^6{\pm}9.5{\times}10^5$, respectively. The 2-h group showed significantly higher signal intensity (p<0.01). The engrafted BMSC showed around the infarct border zones on immunohistochemical examination. The counts of LUC-positive cells revealed the highest number in the 2-h group, in agreement with the results of BLI experiments (p<0.01). Conclusion : In this study, the results suggested that the transplanted BMSC migrated to the infarct border zone in BLI study and the higher signal intensity of LUC-positive cells seen in 2 hrs after MSC transplantation in MCAO mouse model. In addition, noninvasive imaging in real time is an ideal method for tracking stem cell transplantation. This method can be widely applied to various research fields of cell transplantation therapy.