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Cell-cultivable ultrasonic transducer integrated on glass-coverslip (세포 배양 가능한 커버슬립형 초음파 변환자)

  • Keunhyung Lee;Jinhyoung Park
    • The Journal of the Acoustical Society of Korea
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    • v.42 no.5
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    • pp.412-421
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    • 2023
  • Ultrasound brain stimulation is spot-lighted by its capability of inducing brain cell activation in a localized deep brain region and ultimately treating impaired brain function while the efficiency and directivity of neural modulation are highly dependent on types of stimulus waveforms. Therefore, to optimize the types of stimulation parameters, we propose a cell-cultivable ultrasonic transducer having a series stack of a spin-coated polymer piezoelectric element (Poly-vinylidene fluoride-trifluorethylene, PVDF-TrFE) and a parylene insulating layer enhancing output acoustic pressure on a glass-coverslip which is commonly used in culturing cells. Due to the uniformity and high accuracy of stimulus waveform, tens of neuronal cell responses located on the transducer surface can be recorded simultaneously with fluorescence microscopy. By averaging the cell response traces from tens of cells, small changes to the low intensity ultrasound stimulations can be identified. In addition, the reduction of stimulus distortions made by standing wave generated from reflections between the transducers and other strong reflectors can be achieved by placing acoustic absorbers. Through the proposed ultrasound transducer, we could successfully observe the calcium responses induced by low-intensity ultrasound stimulation of 6 MHz, 0.2 MPa in astrocytes cultured on the transducer surface.

A Study on the Environment of Storytelling Based on the History of Japanese Imperialism and Its Problems and Improvements - Around the Militia, Assassination, The Battleship Island, Anarchist from Colony, Dongju and Princess Deokhye - (일제강점기 역사 서사를 중심으로 한 스토리텔링의 환경과 그에 따른 문제점과 개선 방안 연구 - 밀정, 암살, 박열, 동주, 군함도 그리고 덕혜옹주 중심으로 -)

  • Jin, Seung-Hyeon
    • Journal of Korea Entertainment Industry Association
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    • v.13 no.1
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    • pp.1-9
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    • 2019
  • In this paper, it is predicted that the tendency of planning and genre films to produce high - quality films will continue, but it is necessary to have high value and meaningful films and solid storytelling. From the blockbuster warships to arts and low-budget films, the movie genre is centered around fiction and storytelling. However, in the case of Princess Deokhye, it is difficult to recognize any categories of entertainment or artistic due to the fact that it is highly visually and has a high historical status and low awareness. And the distortions of the facts have caused a lot of controversy. However, it seems that Dongju and Park are usually composed of individual - oriented narratives and can be freed from the artistic approach and historical facts in the material. In addition, historical facts should not be distorted or exaggerated. Through this study,

Problem Structuring in IT Policy: Boundary Analysis of IT Policy Problems (경계분석을 통한 정책문제 정의에 관한 연구 - 언론보도에 나타난 IT 정책문제 탐색을 중심으로 -)

  • Park, Chisung;Nam, Ki Bum
    • 한국정책학회보
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    • v.21 no.4
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    • pp.199-228
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    • 2012
  • Policy problems are complex due to diverse participants and their relations in the policy processes. Defining the right problem in the first place is important because Type III error is likely to happen without removing rival hypothesis in defining the problem. This study applies Boundary Analysis suggested by Dunn to structure IT policy problems in Korea. The time frame of the study focuses on 5 years of Lee Administration and data are collected from four newspapers. Using content analysis, the study, first, elaborates total 2,614 policy problems from 1,908 stakeholders. After removing duplicating problems, 369 problems from 323 stakeholders are identified as a boundary of IT policy problem. Among others, failures in government policies are weighted as the most serious problems in IT policy field. However, many significant problems raised by stakeholders dated back to more than a decade, and those are intrinsic problems, which initially caused by market distortions in the IT industry. Therefore, we should be cautious not to overemphasize the most conspicuous problem as the only problem in the policy field when we interpret results of problem structuring.

Automatic Validation of the Geometric Quality of Crowdsourcing Drone Imagery (크라우드소싱 드론 영상의 기하학적 품질 자동 검증)

  • Dongho Lee ;Kyoungah Choi
    • Korean Journal of Remote Sensing
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    • v.39 no.5_1
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    • pp.577-587
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    • 2023
  • The utilization of crowdsourced spatial data has been actively researched; however, issues stemming from the uncertainty of data quality have been raised. In particular, when low-quality data is mixed into drone imagery datasets, it can degrade the quality of spatial information output. In order to address these problems, the study presents a methodology for automatically validating the geometric quality of crowdsourced imagery. Key quality factors such as spatial resolution, resolution variation, matching point reprojection error, and bundle adjustment results are utilized. To classify imagery suitable for spatial information generation, training and validation datasets are constructed, and machine learning is conducted using a radial basis function (RBF)-based support vector machine (SVM) model. The trained SVM model achieved a classification accuracy of 99.1%. To evaluate the effectiveness of the quality validation model, imagery sets before and after applying the model to drone imagery not used in training and validation are compared by generating orthoimages. The results confirm that the application of the quality validation model reduces various distortions that can be included in orthoimages and enhances object identifiability. The proposed quality validation methodology is expected to increase the utility of crowdsourced data in spatial information generation by automatically selecting high-quality data from the multitude of crowdsourced data with varying qualities.

Applicability Evaluation of Deep Learning-Based Object Detection for Coastal Debris Monitoring: A Comparative Study of YOLOv8 and RT-DETR (해안쓰레기 탐지 및 모니터링에 대한 딥러닝 기반 객체 탐지 기술의 적용성 평가: YOLOv8과 RT-DETR을 중심으로)

  • Suho Bak;Heung-Min Kim;Youngmin Kim;Inji Lee;Miso Park;Seungyeol Oh;Tak-Young Kim;Seon Woong Jang
    • Korean Journal of Remote Sensing
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    • v.39 no.6_1
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    • pp.1195-1210
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    • 2023
  • Coastal debris has emerged as a salient issue due to its adverse effects on coastal aesthetics, ecological systems, and human health. In pursuit of effective countermeasures, the present study delineated the construction of a specialized image dataset for coastal debris detection and embarked on a comparative analysis between two paramount real-time object detection algorithms, YOLOv8 and RT-DETR. Rigorous assessments of robustness under multifarious conditions were instituted, subjecting the models to assorted distortion paradigms. YOLOv8 manifested a detection accuracy with a mean Average Precision (mAP) value ranging from 0.927 to 0.945 and an operational speed between 65 and 135 Frames Per Second (FPS). Conversely, RT-DETR yielded an mAP value bracket of 0.917 to 0.918 with a detection velocity spanning 40 to 53 FPS. While RT-DETR exhibited enhanced robustness against color distortions, YOLOv8 surpassed resilience under other evaluative criteria. The implications derived from this investigation are poised to furnish pivotal directives for algorithmic selection in the practical deployment of marine debris monitoring systems.

Correlation Between the Headphone's Acoustical Characteristics and Subjective Preferences (헤드폰의 음향적 특성과 주관적 선호도간의 상관 관계)

  • Lee, Ki-Seung;Lee, Seok-Pil
    • The Journal of the Acoustical Society of Korea
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    • v.28 no.2
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    • pp.96-106
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    • 2009
  • In this paper, correlation between the headphone's acoustical characteristics and the subjective preferences is analyzed, and a possibility of predicting the subjective preferences using the acoustical characteristics is investigated, The headphone's acoustical characteristics include the total harmonic distortions, the variation of the frequency response which were measured by separate channel and the inter-aural correlation coefficients, Those characteristics were measured in a noise-free anechoic chamber, using a head and torso simulator, The subjective preferences were scored in terms of loudness, clearness, spaciousness, fullness and overall impression, In the subjective listening test, 12 subjects were participated who have plentiful listening experiences, The programs include 5 kinds of musics; korean popular song, pop song, light music, male-voice and classic, The 8 models of the headphones were employed, including 4 closed-type circumaural headphones, 2 open-type supraaural headphones and 2 intra-concha headphones, A significant test was carred on the results from the subjective test, using a two-way ANOVA test, The correlation coefficients between the acoustical parameters and the subjective preferences were computed, Experimental results showed that the variation of the magnitude of frequency response measured from a right channel revealed higher correlation with the subjective preferences. Whereas the inter-aural correlation coefficients have very low correlation coefficients.

Histopathological Changes in Cold-Stored Dog Lungs to the Preservation Solutions (냉한에서 보관된 황견의 폐에서 장기 보존액에 따른 조직 세포의 변화)

  • 김해균;이두연
    • Journal of Chest Surgery
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    • v.29 no.8
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    • pp.816-821
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    • 1996
  • Lung transplantation is the established treatment for the end stage lung disedse find preservation of the organ is a major obstacle In performing lung transplantation. For solving this problem, we evaluated the histopathologic changes for various preservation solutions. Male mongrel dogs of similar size and weight (15∼20 kg) were used. The dog lungs were flushed with 4fl normal saline(group 1 'n:5): Modified Euro-Collins solution(group 2 n:5) and University of Wisconsin solution (group 3 : n=6), 60m11kg through a catheter placed in the main pulmonary artery aft r flushing of PGE 1 (20ng1kg). The lungs were preserved for 60 hours and measured dry and wet weights. Histologic specimens were taken every 6 hours and %toed for light microscopic evaluation. The edema ratio of the lungs peaked in 12 hours although there was no difference between the groups. Histologically, alveolar septal changes developed in one case (20%) after 1 hour preservation with normal saline. In case of the University of Wisconsin solution, the alveolar septal distortions and swellings were seen in 1 cases (20%) after 6 hours preservation compared with 3 cases (60%) after 6 hours preservation with Modified Euro-Collins solution. Changes of the pneumocytes were observed after 24 hours preser- vation in group 1, after 48 hours preservation in group 2 and after 60 hours preservation in group 3. We conclude that University of Wisconsin solution might have a superior preservation effect compare to normal saline and Modified Euro-Collins solutions.

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Differences of Illness Behavior in Depressive Patients According to the Presence of Somatization (우울증 환자에서 신체화 증상에 따른 질병행동의 차이)

  • Yoon, Chang-Young;Jang, Se-Heon;Jae, Young-Myo;Lee, Dae-Su;Choi, Jin-Hyuk
    • Korean Journal of Psychosomatic Medicine
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    • v.17 no.2
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    • pp.68-74
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    • 2009
  • Objectives : Illness behavior is defined as the persistence of an adaptive/maladaptive mode of perceiving, evaluating and responding to health status and symptoms according to the status. In a cognitive aspect, somatizing symptoms are regarded as being originated from distortions, including magnification and/or amplification, of perceiving, evaluating and responding to symptoms such as bodily sensations. That is somatization may be explained by maladaptive illness behavior. In this study, we tried to investigate differences of illness behavior in depressive patient according to the presence of somatization. Methods : We divided 45 patients who were diagnosed as depression with ICD-10 diagnostic criteria into two groups(somatizing and non-somatizing group) according to the somatization subscale of Korean Depression Scale and compared two groups in the differences of illness behavior using the Illness Behavior Questionnaire. Results : Somatizing group showed significantly higher scores than non-somatizing group on the disease affirmation subscale($6.79{\pm}2.08$ vs. 4.76, p=0.003) and the denial subscale($3.25{\pm}1.22$ vs. $2.10{\pm}1.41$, p=0.006). There were no significant differences between two groups on the general hypochondriasis subscale and the affective unstability subscale. In a logistic regression analysis, somatizing group also showed higher odds ratio (OR) scores on the disease affirmation subscale(OR=1.418, p=0.089) and the denial subscale(OR=1.880, p=0.083). Conclusion : The disease affirmation and denial may be a discriminative mechanism of somatization in depressive patients. These subscales of Illness Behavior Questionnare could be useful markers, and psychiatric illnesses with somatizing and depressive symptoms may be differentially diagnosed and be predicted through these subscales.

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Volume Rendering System of e-Science Electron Microscopy using Grid (Gird를 이용한 e-사이언스 전자현미경 볼륨 랜더링 시스템)

  • Jeong, Won-Gu;Jeong, Jong-Man;Lee, Ho;Choe, Sang-Su;Ahn, Young-heon;Hur, Man-Hoi;Kim, Jay;Kim, Eunsung;Jung, Im Y.;Yeom, Heon Y.;Cho, Kum Won;Kweon, Hee-Seok
    • Proceedings of the Korea Contents Association Conference
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    • 2007.11a
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    • pp.560-564
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    • 2007
  • Korea Basic Science Institute(KBSI) has three general electron microscopes including High Voltage Electron Microscope(HVEM) which is the only one in Korea. Observed images through an electron microscope are what they are tilted by each step and saved, offering the more better circumstances for observers, a reconstruction to 3D could be a essential process. In this process, a warping method decreases distortions maximumly of avoided parts of a camera's focus. All these image treatment processes and 3D reconstruction processes are based on an accompaniment of a highly efficient computer, a number of Grid Node Personal computers share this process in a short time and dispose of it. Grid Node Personal computers' purpose is to make an owner can share different each other and various computing resources efficiently and also Grid Node Personal computers is applying to solve problems like a role scheduling needed for a constructing system, a resource management, a security, a capacity measurement, a condition monitoring and so on. Grid Node Personal computers accomplish roles of a highly efficient computer that general individuals felt hard to use, moreover, a image treatment using the warping method becomes a foundation for reconstructing to more closer shape with an real object of observation. Construction of the electron microscope volume 랜더링 system based on Grid Node Personal computer through the warping process can offer more convenient and speedy experiment circumstances to observers, and makes them meet with experiment outcome that is similar to real shapes and is easy to understand.

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The Effect of Mean Brightness and Contrast of Digital Image on Detection of Watermark Noise (워터 마크 잡음 탐지에 미치는 디지털 영상의 밝기와 대비의 효과)

  • Kham Keetaek;Moon Ho-Seok;Yoo Hun-Woo;Chung Chan-Sup
    • Korean Journal of Cognitive Science
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    • v.16 no.4
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    • pp.305-322
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    • 2005
  • Watermarking is a widely employed method tn protecting copyright of a digital image, the owner's unique image is embedded into the original image. Strengthened level of watermark insertion would help enhance its resilience in the process of extraction even from various distortions of transformation on the image size or resolution. However, its level, at the same time, should be moderated enough not to reach human visibility. Finding a balance between these two is crucial in watermarking. For the algorithm for watermarking, the predefined strength of a watermark, computed from the physical difference between the original and embedded images, is applied to all images uniformal. The mean brightness or contrast of the surrounding images, other than the absolute brightness of an object, could affect human sensitivity for object detection. In the present study, we examined whether the detectability for watermark noise might be attired by image statistics: mean brightness and contrast of the image. As the first step to examine their effect, we made rune fundamental images with varied brightness and control of the original image. For each fundamental image, detectability for watermark noise was measured. The results showed that the strength ot watermark node for detection increased as tile brightness and contrast of the fundamental image were increased. We have fitted the data to a regression line which can be used to estimate the strength of watermark of a given image with a certain brightness and contrast. Although we need to take other required factors into consideration in directly applying this formula to actual watermarking algorithm, an adaptive watermarking algorithm could be built on this formula with image statistics, such as brightness and contrast.

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