• 한국환경과학회지
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• 제3권1호
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• pp.39-47
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• 1994

Dispersion characteristics of air pollutants in the mountainous coastal area are investigated in considering with the mesoscale local circulations using a two dimensional numerical model with two kinds of topograpy of 500m and 300m. In the model, land-sea breezes and mountain-valley wind are mainly considered under the condition of the absence of large scale prevailing flow in the circulation analysis, and the pollutants dispersion is traced by the Lagrangian methods. According to the results, the wind velocity is affected by topography and is stronger in the case of 500m height mountain than that of 300m, the Pollutants that source is near the coast transported over the mountain and dispersed to behind inland area. It is classified that the topography change control affects the wind velocity and the circulations. The pollutants that source is different transported and concentrated to behind inland and/or diffused to the sea area by the combination of the wind system with topographic changes. The results can be applied to the air pollution control with the arrangement design of industrial area and the planning of coastal developments.

• 한국대기환경학회지
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• 제23권4호
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• pp.405-419
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• 2007

A series of tracer experiments for the evaluation of atmospheric dispersion was performed over the urban area of Seoul using two inert, non-deposition perfluorocarbon (PMCH and m-PDCH) gases during three years campaign on 2002, 2003 and 2005. 30 sampling sites for collecting these tracers were located along two arcs of 2.5 and 5 kilometers downwind from the release point. About ten measurements which each lasted for 2 hours or 4 hours were made over the two consecutive days during each campaign. CALPUFF and MM5 meteorological model were applied to evaluate the urban dispersion in detail. Size of Modeling domain was $27\;km{\times}23\;km$ and the fine nest in the modeling domain had a grid size of 0.5 km. The results showed that CALPUFF dispersion model had a tendency to estimate tracer concentrations about $2{\sim}5$ times less than those of ambient samples under many conditions. These consistent inaccuracy in urban dispersion was attributed to inherent inaccuracy and lack of details in terrain data at urban area.

• 지구물리와물리탐사
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• 제9권2호
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• pp.148-154
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• 2006

소규모 천부 불균질대가 레일리파의 전파 및 분산특성에 미치는 영향에 대해 알아보기 위해 반무한 균질 매질과 2층 층서구조상의 소규모 천부 불균질대를 상정하고 이 불균질대의 심도, 규모 등을 변화시키면서 레일리파의 전파양상과 분산특성에 대해 고찰하였다. 불균질대의 크기가 최소파장을 기준으로 한파장 이상의 경우 레일리파의 분산 현상이 확인되었으며 이러한 현상은 불균질대의 크기가 클수록 커지며 심도가 깊어질수록 작아지고 심도와 수직적 크기변화보다는 수평적 크기변화에 더 민감한 것을 확인하였다. 분산으로 인한 위상속도의 변화 양상은 불균질대의 크기가 일정정도 이하일 경우에는 탄성파 기록상에서는 확인하기 어려우나 분산된 레일리파의 반사 및 투과 이벤트와 그로 인한 진폭변화를 통해 불균질대 존재 여부를 확인하는 지시자로 사용될 수 있을 것으로 판단되며 이런 결과는 소규모 불균질대나 공동탐지를 위한 현장탐사나 새로운 해석방법 개발에 있어 한 지침을 제공할 것으로 기대된다.

• 응용통계연구
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• 제4권2호
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• pp.129-135
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• 1991

위치와 척도 모수에 대하여 간단히 $L_1$ 불편 추정량을 구하는 방법을 요약 소개하고, $L_1$ 불편 추정량에 대한 자연적인 퍼짐의 측도로 제안된 diffusivity를 이용하는 예를 든다.

• Advances in nano research
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• 제8권4호
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• pp.283-292
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• 2020

In the present research, differential quadrature (DQ) method has been utilized for investigating free vibrations of porous functionally graded (FG) micro/nano beams in thermal environments. The exact location of neutral axis in FG material has been assumed where the material properties are described via porosity-dependent power-law functions. A scale factor related to couple stresses has been employed for describing size effect. The formulation of scale-dependent beam has been presented based upon a refined beam theory needless of shear correction factors. The governing equations and the associated boundary conditions have been established via Hamilton's rule and then they are solved implementing DQ method. Several graphs are provided which emphasis on the role of porosity dispersion type, porosity volume, temperature variation, scale factor and FG material index on free vibrational behavior of small scale beams.

• Environmental Engineering Research
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• 제22권1호
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• pp.75-86
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• 2017

The aerosol content dynamics in a virtual system were investigated. The outcome was extended to monitor the mean concentration diffusion of aerosols in a predefined macro and micro scale. The data set used were wind data set from the automatic weather station; satellite data set from Total Ozone Mapping Spectrometer aerosol index and multi-angle imaging spectroradiometer; ground data set from Aerosol robotic network. The maximum speed of the macro scale (West Africa) was less than 4.4 m/s. This low speed enables the pollutants to acquire maximum range of about 15 km. The heterogeneous nature of aerosols layer in the West African atmosphere creates strange transport pattern caused by multiple refractivity. It is believed that the multiple refractive concepts inhibit aerosol optical depth data retrieval. It was also discovered that the build-up of the purported strange transport pattern with time has enormous potential to influence higher degrees of climatic change in the long term. Even when the African Easterly Jet drives the aerosols layer at about 10 m/s, the interacting layers of aerosols are compelled to mitigate its speed to about 4.2 m/s (macro scale level) and boost its speed to 30 m/s on the micro scale level. Mean concentration diffusion of aerosols was higher in the micro scale than the macro scale level. The minimum aerosol content dynamics for non-decaying, logarithmic decay and exponential decay particulates dispersion is given as 4, 1.4 and 0 respectively.

• 대한기계학회논문집
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• 제19권5호
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• pp.1300-1307
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• 1995

The effect of thermal stratification on the turbulent dispersion from a fine cylindrical heat source was experimentally examined in a wind tunnel with and without a strong temperature gradient. A 0.5 mm dia. nichrome wire was used as a line heat source. Turbulent intensities, r.m.s. value of temperature and convective heat fluxes were measured by using a hot-wire and cold-wire combination probe. The results show that the peack value and the spread of the vertical turbulent intensity for the stratified case are far lower than those in the neutral case, which indicates that the stable temperature gradient suppresses the vertical velocity component. All of the third order moments including heat fluxes measured in the stable condition have very small values than those of the neutral case. This nature suggests that the decrease of scalar fluctuations in the stably stratified flow is mainly due to the suppression ofthe turbulent diffusion processes by the stable stratification. A simple gradient model with a composite timescale which has a simple weighted algebraic mean between dynamic and thermal time scale yields reasonably good numerical values in comparison with the experimental data.

• 상하수도학회지
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• 제23권4호
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• pp.397-406
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• 2009

This study was conducted to monitor the floc sizes forming in the mixing zone in the water treatment plant. The dosing amount of poly aluminium chloride(PAC) was determined by particle dispersion analyzer(iPDA) in the lab and field scale test. During a field test period, PAC coagulant was used and the raw water was taken from Nakdong river. PAC wad diluted to activate the coagulant, leading to bring the more homogeneous dispersion in the shorter time. To monitor the floc sizes, the unit of floc size index(FSI) was used. With increasing of raw water turbidity, FSI value was increased. Also, the increased dosing amount of PAC brought the increased FSI and with overdosing of coagulant was in turn decreased. When the PAC was fed into the raw water after dilution in a field scale test, the width of FSI was narrower compared with the feeding of the mother liquor of PAC, implying that the formed flocs are denser and more uniform sizes. The width of FSI in average was varied on depending on the basicity of coagulant. Also, dF value, fractal dimension was evalued with the different coagulants, showing from 2.01 to 2.03. On-line floc monitor was effective for the optimal dosing in the drinking water plant.

• 방사선산업학회지
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• 제4권1호
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• pp.79-83
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• 2010

The pollutants in subsurface soil are advected by groundwater flow and transported by the hydrodynamic dispersion. In this study, laboratory-scale experiments by using a radioisotope were conducted to evaluate the characteristics of the transport and dispersion of pollutants in the soil. The hydraulic model of the laboratory-scale was manufactured based upon its geometric similarity. Tc-99m having a short half-life was used with a tracer and it was injected instantaneously into the soil. Tc-99m milked from a $^{99}Mo/^{99m}Tc$ portable generator fabricated for medical purposes had 0.141 MeV of gamma radiation. The experiments are performed by the different conditions like the variations of groundwater velocity and the results are analyzed by the measured CPS of Tc-99m.

• Journal of Pharmaceutical Investigation
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• 제38권4호
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• pp.241-247
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• 2008

Paclitaxel is a taxane diterpene amide, which was first extracted from the stem bark of the western yew, Taxus brevifolia. This natural product has proven to be useful in the treatment of a variety of human neoplastic disorders, including ovarian cancer, breast and lung cancer. Paclitaxel is a highly hydrophobic drug that is poorly soluble in water. It is mainly given by intravenous administration. Therefore, The pharmaceutical formulation of paclitaxel ($Taxol^{(R)}$; Bristol-Myers Squibb) contains 50% $Cremophor^{(R)}$ EL and 50% dehydrated ethanol. However the ethanol/Cremophor EL vehicle required to solubilize paclitaxel in $Taxol^{(R)}$ has a pharmacological and pharmaceutical problems. To overcome these problems, new formulations for paclitaxel that do not require solubilization by $Cremophor^{(R)}$ EL are currently being developed. Therefore this study utilized a supercritical fluid antisolvent (SAS) process for cremophor-free formulation. To select hydrophilic polymers that require solubilization for paclitaxel, we evaluated polymers and the ratio of paclitaxel/polymers. HP-${\beta}$-CD was used as a hydrophilic polymer in the preparation of the paclitaxel solid dispersion. Although solubility of paclitaxel by polymers was increased, physical stability of solution after paclitaxel/polymer powder soluble in saline was unstable. To overcome this problem, we investigated the use of surfactants. At 1/20/40 of paclitaxel/hydrophilic polymer/ surfactant weight ratio, about 10 mg/mL of paclitaxel can be solubilized in this system. Compared with the solubility of paclitaxel in water ($1\;{\mu}g/mL$), the paclitaxel solid dispersion prepared by SAS process increased the solubility of paclitaxel by near 10,000 folds. The physicochemical properties was also evaluated. The particle size distribution, melting point and amophorization and shape of the powder particles were fully characterized by particle size distribution analyzer, DSC, SEM and XRD. In summary, through the SAS process, uniform nano-scale paclitaxel solid dispersion powders were obtained with excellent results compared with $Taxol^{(R)}$ for the physicochemical properties, solubility and pharmacokinetic behavior.