• 대한의생명과학회지
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• 제12권3호
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• pp.267-274
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• 2006

Klebsiella pneumoniae is the leading cause of nasocomial infection and the most commonly isolated from clinical specimens. $Extended-spectrum-{\beta}-lactamase$ (ESBL) producing K. pneumoniae infection was associated with a significantly longer duration of hospital stay and greater hospital charges. The purpose of this study is to investigate the antibiotic resistant patterns and the DNA fingerprint types of extended-spectrum ${\beta}-lactamase$ (ESBL) producing K. pneumoniae. 223K. pneumoniae strains were collected from three general hospitals with more than 500 beds in Busan, Korea from September 2004 to October 2005. The minimum inhibitory concentration (MIC) of antibiotics was measured using the Gram negative susceptibility (GNS) cards of VITEK (Vitek system, Hazelwood Inc., MO). Random amplified polymorphic DNA method was used to detect DNA fingerprint of the organisms. Of the 226 K. pneumoniae isolates 65 ESBL-producing K. pneumoniae strains were detected by the Vitek system and confirmed by the double-disk synergy test. All the 65K. pneumoniae strains were resistant cefazolin, cefepime, ceftriaxone and aztreonam, and 83.0% of the organisms were resistant to ampicillin/sulbactam, 66.1% to tobramycin, 67.6% to piperacillin/tazobactam, 61.5% to ciprofloxacin, and 47.6% to trimethoprim/sulfamethoxazole and 43.0% to gentamicin. The RAPD patterns were distincted as 10 types by three random 10-mer primers (208, 272, 277). Among ten type patterns, three types (Ic, IIb, IIIe) were remarkably represented at patient of internal department, nerve surgery department, general surgery department, and neonatal room. These results indicate that RAPD can be useful for DNA of strains typing in the epidemiological investigations. Therefore more investigation are needed in order to prevent the ESBL type-producing K. pneumoniae from spreading resistance to oxyimino cephalosphorin antibiotics.

• 설비공학논문집
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• 제6권4호
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• pp.439-452
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• 1994

One of the chlorofluorocarbon compounds. R-12 deplete atmospheric ozone. It leads to international agreement to reduce CFC production. R-134a has similar thermodynamic properties to CFC-12. It has zero ODP(Ozone Depletion Potential). This Paper focuses on the lubricating oils for using with R-134a PAGs(Polyalkylene Glycol's) and esters are primary lubricants that are now being tested for use with R-134a Because of extreme polarity of R-134a. there are many problems in the selection of lubricating oil. This investigation analyzes compressor working conditions and calculates wear parts friction for simulation testing. Miscibility and material compatibility is proved by sealed glass tests. Friction was tested on the closed type pin on disk wear tester. This equipment simulates actual refrigerating compressor. Environment controlled test made more reliable result than field test Conventional oils(mineral oils, Alkylbenzene, PAO(Polyalpha Olefin) are immiscible with R-134a. PAGs and ester oils are miscible with R-134a. Friction coefficient is similar to conventional system(mineral oil/R-12 systems) at operating condition. At start & stop condition, PAGs/R-134a system has high friction coefficient. It provide reliable result on the lubricity, miscibility, material compatibility of R-134a with these new lubricants. It suggests proper selection of refrigeration oil that may improve compressor durability of performance.

• 센서학회지
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• 제24권4호
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• pp.239-246
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• 2015

Blood pressure is possible to diagnose a disease associated with blood pressure and judgment the current health of patients. Automatic blood pressure monitor capable of measuring a blood pressure easily in hospital and at home have become spread. In this study, we developed the blood pressure simulator (BPS) that can test the arm-type automatic blood pressure monitor that is commonly used in hospital. BPS is to produce a pressure similar to the pressure wave generated in the human blood using a servo disk motor. Then, using the silicon tube, it implements the situations such as human blood vessels, and to output the generated pressure waveform. Simply the BPS's phantom put on the cuff and it is able to simulate blood pressure. So anyone can quickly test the blood pressure monitor within one minute and it is possible to shorten the test time required for the automatic blood pressure monitor. In Performance test, the trends and the standard deviation of the values measured in the BPS is similar to the value of the measured pressure from people with normal blood pressure. Thus, the development BPS showed a possibility of taking into account the actual blood pressure measurement environment simulator.

• Restorative Dentistry and Endodontics
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• 제24권4호
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• pp.604-613
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• 1999

This study was performed to evaluate the effect of resin and filler type on the fracture toughness of light-activated composites. Experimental composites were prepared using urethane tetramethacrylate(UTMA) and bisphenol glycidylmethacrylate(Bis-GMA) monomers and five different types of silica fillers. Fracture toughness was measured by a single edge V-notched beam(SEVNB) method, which was discussed from ASTM E399-78. Rectangular bars of $2.5{\times}5{\times}26mm$ were prepared with experimental composites and a notch about 2.25mm deep was carved at the center of the long axis of the specimen using a dental diamond disk driven by a dental micro engine. The flexural test was carried out at a crosshead speed of 0.05mm/min and fracture surfaces were observed under scanning electron microscope. The results obtained were summarized as follows: 1. The fracture toughness values of UTMA-based composites were relatively higher than those of Bis-GMA-based composites. 2. The highest fracture toughness value was observed in the UTMA-based composite containing the $1.5{\mu}m$-spherical fillers. 3 Aging in the distilled water at $37^{\circ}C$ for 10 days showed the increase of fracture toughness, which was severer in the Bis-GMA-based composites than those of UTMA-based composites. 4. The AE amplitude occurring during the fracture toughness tests was the highest at the point of macroscopic fracture.

• 대한치과보철학회지
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• 제38권4호
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• pp.438-445
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• 2000

The ideal restorative material should mimic the properties of the tissues it replaces. Dental composite resins have been used widely as restorative materials due to its advantages such as excellent esthetics and ease of manipulation. But inadequate wear resistance has been a major factor limiting the use of composite restorative materials. Improved manufacturing techniques have allowed the development of hybrid composites, with a greater percentage volume filler loading, which have improved physical and mechanical properties. However they are lacking in the study of wear resistance. The purpose of this study was to evaluate the wear of human enamel against ceromer by the use of a pin-on-disk type wear testers. Discs of ceromer(Targis ; lvoclar Vivadent, Amherst. NY) and discs of type III gold alloy as a control were used f9r test specimens. Intact cusp of premolar and molar were used for enamel specimens. The wear of enamel was determined by weigh-ing the cusp before and after each test, and the weight converted to volumes by average densi-ty of enamel. Surface profilometer was used to quantify wear of the ceromer and gold specimens. Vicker's hardness tester was used to evaluate the surface hardness of test specimens. The SEM was used to evaluate the wear surfaces The results were as follows; 1. Ceromer produced less enamel wear than gold(p<0.05) 2. The wear volume of ceromer was greater than that of gold(p<0.01) 3. The hardess of ceromer was lower than that of gold, but there was no correlation between the hardness and wear of the ceromer and gold. 4. SEM analysis revealed that there were many voids and microcracks in the wear tract of ceromer In gold group, many minute V-shaped grooves were examined.

• 한국정보통신학회논문지
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• 제15권3호
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• pp.528-535
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• 2011

본 논문에서는 고주파 발진회로의 공진기가 안테나로 동작하는 2.4GHz 대역의 능동 안테나를 이용하여 이동체의 거리를 측정할 수 있는 소형 도플러 센서를 제안하였다. 이동체의 움직임에 비례하여 고주파 발진주파수의 편이를 발생시키며 이를 검출하는 회로를 통해 제안된 구조의 동작을 확인하였다. 설계 제작된 거리 감지 센서는 직경이 30mm, 높이 4.2mm 정도로 매우 작은 원형디스크 형태를 갖으며, 안테나는 2.35GHz에서 약 120도의 빔폭과 전방향 방사특성을 나타내었다. 센서의 감도 측정결과, 1m 떨어져 움직이고 있는 도체판에 대해 약 240mV의 도플러 신호 전압을 얻었고, 자유낙하 실험으로부터 지표위의 5m 지점에서부터 지표면까지 선형적인 전압크기의 증가를 보였다.

• 혜화의학회지
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• 제19권1호
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• pp.119-128
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• 2010

Objective : Lower back pain is the most common pain in our life, and Heniated Intervetebral Disk(HIVD) of L-spine is one of the most common disease that cause lower back pain. This study is designed to invertigate the general distributions for HIVD patients. Subjects and Methods : The 193 patients who had taken diagnosis of HIVD by L-spine CT or L-spine MRI and admitted to Cheonan oriental medical hospital in Daejon university from January 2008 to December 2009 were reviewed. They were analyzed according to sex, age, prevalent duration, and causing factor. They were treated with acupuncture, herbal medicine and physical therapy. And treatment efficacy was evaluated according to each distribution respectively. Result 1. Among 193 patients, males were more than females in the ratio of 1.47:1. 2. According to age, 33.2% patients were thirties. 3. According to causing factor, 39.9% patients with unknown origin were most. 4. According to prevalent duration, 49.7% patients were on acute stage and 20.2% patients were on 6-10days. 5. According to HIVD types, patients with protruded disc type and with lesion of L4-5 were most common respectively 45.1%, 63.3%. 6. When effective rates were analyzed according to each distribution, patients on twenties, acute stage and with extruded disc type were showed good effective rates, respectively 92.7%, 90.6%, 89.3%. Conclusion: Total effect rate was 87.5%. Prevalence of HIVD is the highest in the age of 30 to 40, L4-5 occupy the most. And early treatment was better than late treatment.

• Tribology and Lubricants
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• 제36권6호
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• pp.332-341
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• 2020

High-speed turbomachinery implements gas foil bearings (GFBs) due to their distinctive advantages, such as high efficiency, lesser part count, and lower weight. This paper provides the test results of the static structural stiffnesses and loss factors of bump-type foil thrust bearings with increasing preload and bearing deflection. The focus of the current work is to experimentally quantify variability in structural stiffnesses and loss factors among the four test thrust bearings with identical design values and material of the bump and top foil geometries using the same (open-source) fabrication method. A simple test setup, using a rigidly mounted non-rotating shaft and thrust disk, measures the bearing bump deflections with increasing static loads on the test bearing. The inner and outer diameters of the test bearings are 41 mm and 81 mm, respectively. The loss factor, best-representing energy dissipation in the test bearings, is estimated from the area inside the local hysteresis loop of the load versus the bearing deflection curve. The measurements show that structural stiffnesses and loss factors of the test bearings significantly rely on applied preloads and bearing deflections. Local structural stiffnesses of the test bearings increase with applied preloads but decrease with bearing deflections. Changes of loss factors are less sensitive to applied preloads and bearing deflections compared to those of structural stiffnesses. Up to 35% variability in static load structural stiffnesses is found between bearings, while up to 30% variability in loss factors is found between bearings.

• 미생물학회지
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• 제46권1호
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• pp.38-45
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• 2010

본 연구는 부산 환경관리공단 수영사업소 산하 수영공공하수종말처리장 하수로부터 광범위 베타락탐 분해효소(ESBL, extended-spectrum ${\beta}$-lactamase)의 유형을 파악하기 위하여 이루어졌다. 수영공공하수처리시설은 부산광역시의 동북부 생활하수와 수세식변기의 오수가 표준활성슬러지공법으로 처리되며 일 생활하수 처리량은 총 550,000톤이다. 이중디스크 확산 검사, 제 3세대 세파계열 항균제에 대한 최소억제농도 시험을 통하여 14균주를 선별하였다. Indole, methyl-red, Voges-Proskauer, Simmon's citrate, decarboxylase-dihydrolase 시험과 당 발효 시험 등 생화학 검사를 통하여 동정한 결과 Escherichia coli (10균주), Klebsiella pneumoniae (4균주)가 동정되었다. 이를 전달균주로, sodium azide에 내성을 가진 피전달 균주인 E. coli J53에 교차접합을 시켜 11균주 (E. coli 9균주, K.pneumoniae 2균주)가 접합이 이루어졌다. 접합자중 2균주는 ESBL 유전자를 전달받지 못하였고 9균주는 부모로부터 ESBL 유전자를 전달받았다. 등전점, 유전자서열과 단백질서열 분석 등을 통하여 피전달균주인 E. coli J53에 전달된 유전자유형은 TEM형의 모형인 TEM-1과 SHV-12형으로 규명되었다.

• 한국식품위생안전성학회지
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• 제17권1호
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• pp.31-35
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• 2002

2000년 국내 식중독발생 통계에 따르면, 원인식품별 식중독발생건수는 육류 등이 27.9%, 어패류 및 가공품이 26.0%, 복합조리식품(김밥, 도시락)이 24.0%의 비율을 차지하고 있으며, 원인균별 식중독발생건수는 Salmonella spp.가 28.8%로 1위, Vibrio parahaemolyticus가 13.5%로 2위, Staphylococcs aureus가 8.7%로 3위를 차지하고 있다. 이에 본 연구에서는 김밥 중 황색포도상구균에 대한 분포도조사 및 오염정도를 분석하여 위해도평가의 기초자료로 활용하고자 하였다. 서울, 부산, 대전, 광주의 백화점, 편의점, 분식점 등에서 구입한 김밥 총 214건에 대한 황색포도상구균의 정량 및 정성실험 결과, 균검출율은 34.1%였고, 평균균량은 623 cfu/g 이었다. 분리균에 대한 enterotoxin 실험결과 A type 42.5%(31주/73주), B type 4.1%(3주/73주), D type 2.7%(2주/73주)의 분포를 보였다. 또한 유통·판매형태별로는 분식점의 검출율이 42.8%로 백화점(25.8%)및 편의점(12.3%)보다 높게 나타났으며, 계절별 평균균검출율은 비슷하였으나, 정량검사결과 여름철(793 cfu/g)에 겨울철(446 cfu/g)보다 균량이 1.8배 높게 나타났다.