• The Journal of Korean Institute of Communications and Information Sciences
• /
• v.24 no.7A
• /
• pp.1028-1035
• /
• 1999

To increase the throughput of data transmission in burst-mode TDMA communication systems and also to get a good BER performance at the same time, it is essential to rapidly acquire the carrier while keeping the desirable tracking performance. To achieve this goal, in this paper, a new decision-directed carrier recovery algorithm is presented. The proposed scheme does not incorporate the PLL and suppress the Gaussian random process of input noise by the pre-stage low pass filter so as to get both the fast acquisition and a good performance. Through computer simulations, the performance of the scheme is analyzed with respect to the acquisition time and bit error rate. The cycle slip in the proposed scheme is seldom observed at very low SNR environment in contrast to the previous proposed one. Because of this merit, it is not required to do the differential encoding and decoding in the proposed scheme.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
• /
• v.19 no.4
• /
• pp.435-446
• /
• 2021

This article examines the consequences of a significant spent fuel management decision or event in the United States, South Korea and Taiwan. For the United States, it is the financial impact of the Department of Energy's inability to take possession of spent fuel from commercial nuclear power companies beginning in 1998 as directed by Congress. For South Korea, it is the potential financial and socioeconomic impact of the successful construction, licensing and operation of a low and intermediate level waste disposal facility on the siting of a spent fuel/high level waste repository. For Taiwan, it is the operational impact of the Kuosheng 1 reactor running out of space in its spent fuel pool. From these, it draws six broad lessons other countries new to, or preparing for, nuclear energy production might take from these experiences. These include conservative planning, treating the back-end of the fuel cycle holistically and building trust through a step-by-step approach to waste disposal.

• Journal of Korean Elementary Science Education
• /
• v.35 no.1
• /
• pp.54-64
• /
• 2016

The purpose of this study is to develop instructional strategy which utilizes thinking maps focused on drawing as a measure to enhance science learning motivation, self-directed learning activity and science academic achievement of learners, and to examine the effects of its application. The target unit for this study is 'life cycle of plants' in the fourth grade of elementary school. Two classes of 4th grades of elementary school were selected and divided into two groups. The learners of experimental group have completed thinking map by drawing a picture to express the results to be observed and measured, and used it to arrange the learning contents. The result of this study is as follows. First, it is proven that using thinking maps focused on drawing actually helped improving the motivation of learners to study science. Second, it is proven that this strategy was effective to change their self-directed learning ability in positive ways. Third, it contributed to the improvement of learners' science academic achievement. We found out that the application of this strategy enabled them to enjoy the mapping using drawing, to be immersed in learning, to better recognize the scientific concepts and the structure of learning contents, and to have a positive awareness of the usefulness of thinking maps focused on drawing.

• BMB Reports
• /
• v.57 no.1
• /
• pp.30-39
• /
• 2024

Directed evolution (DE) of desired locus by targeted random mutagenesis (TRM) tools is a powerful approach for generating genetic variations with novel or improved functions, particularly in complex genomes. TRM-based DE involves developing a mutant library of targeted DNA sequences and screening the variants for the desired properties. However, DE methods have for a long time been confined to bacteria and yeasts. Lately, CRISPR/Cas and DNA deaminase-based tools that circumvent enduring barriers such as longer life cycle, small library sizes, and low mutation rates have been developed to facilitate DE in native genetic environments of multicellular organisms. Notably, deaminase-based base editing-TRM (BE-TRM) tools have greatly expanded the scope and efficiency of DE schemes by enabling base substitutions and randomization of targeted DNA sequences. BE-TRM tools provide a robust platform for the continuous molecular evolution of desired proteins, metabolic pathway engineering, creation of a mutant library of desired locus to evolve novel functions, and other applications, such as predicting mutants conferring antibiotic resistance. This review provides timely updates on the recent advances in BE-TRM tools for DE, their applications in biology, and future directions for further improvements.

• Proceedings of the Korean Operations and Management Science Society Conference
• /
• 1993.10a
• /
• pp.118-118
• /
• 1993

We consider a discrete event dynamic system called periodic job shop, where an identical mixture of items called minimal part set(MPS) is repetitively produced in the same processing order and the primary performance measure is the cycle time. The precedence relationships among events(starts of operations) are represented by a directed graph with rocurront otructure. When each operation starts as soon as all its preceding operations complete(called earliest starting), the occurrences of events are modeled in a linear system using a special algebra called minimax algebra. By investigating the eigenvalues and the eigenvectors, we develop conditions on the directed graph for which a stable steady state or a finite eigenvector exists. We demonstrate that each finite eigenvector, characterized as a finite linear combination of a class of eigenvalue, is the minimum among all the feasible schedules and an identical schedule pattern repeats every MPS. We develop an efficient algorithm to find a schedule among such schedules that minimizes a secondary performance measure related to work-in-process inventory. As a by-product of the linear system approach, we also propose a way of characterizing stable steady states of a class of discrete event dynamic systems.

• The Journal of the Institute of Internet, Broadcasting and Communication
• /
• v.22 no.6
• /
• pp.91-97
• /
• 2022

There is hare and tortoise racing algorithm(HTA) for single-source(SS) singly linked list(SLL) with O(n) time complexity. But the fast method is unknown for general graph with multi-source, multi-destination, and multi-branch(MSMDMB). This paper suggests linear time cycle detection algorithm for given undirected and digraph with MSMDMB. The proposed method reduced the given graph G contained with unnecessary vertices(or nodes) to cycle into reduced graph G' with only necessary vertices(or nodes) to cycle based on the condition of cycle formation. For the reduced graph G', we can be find the cycle set C and cycle length λ using linear search within linear time. As a result of experiment data, the proposed algorithm can be obtained the cycle for whole data.

• Journal of Life Science
• /
• v.11 no.4
• /
• pp.362-370
• /
• 2001

Regulation of cell proliferation is a complex process involving the regulated expression and /or modification of discrete gene products. which control transition between different stages of the cycle. The purpose of this short review is to provide an overview of somatic cell cycle events and their controls. Cycline have appeared as major positive regulators in this network, because their association to the cyclin-dependent kinases(Cdks) allows the subsequent activation on the Cdk/cyclin complexes and their catalatic activity. In mammalian cells, early to mid G1 progression and late G1 progression leading to S phase entry are directed by D-type cyclins-Cdk4, 6 and cyclin E-Cdk 2 both of which can phosphorylate the retinoblastoma protein (pRB). pRB is a transcriptional repressor which, in its unphosphorylated state, binds to members of the E2F transcription factor family and blocks E2F-dependent transcription of genes controlling the G1 to S phase transition an subsequent DNA synthesis. Cyclin A is produced in late G1 and expressed during S and G2 phae, and expression of B-type cyclins is typically maximal during the G2 to M phase transition and it controls the passage through M phase. They primarily associate with the activate Cdk2, and Cdc2, respectively. On the other hand, the Cdk inhibitors negatively control the activity of C아/cyclin complex by coordinating internal and/or external signals and impending proliferation at several key checkpoints. These current and further findings will provide novel approaches to understanding and treating major diseases.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1995.10a
• /
• pp.9-15
• /
• 1995

When quiescent cells ate stimulated to enter the cell cycle, the thymidine kinase(TK) gene is transcriptionally activated at the border of Gl and 5. In this report we show that the human TK promoter contains multiple protein-binding sites. By site-directed mutagenesis, we identified a protein-binding site on the human TK promoter requited for conferring Gl-S-regulated transcription to a heterologous promoter and dissociated it functionally from an adjacent protein-binding domain containing an inverted CCAAT motif requited for high basal level expression. Substitution-mutation of this site results in constitutive expression of the neo reporter gene in serum-stimulated fibroblasts, as well as in cells arrested in mid-Gl by a temperature-sensitive mutation. The regulatory domains for the human TK promoter exhibit interesting symmetrical features, including a set of CCAAT motifs and sites similar to the novel Yi protein-binding site recently discovered in the mouse TK promoter. Thus, components of the hTK complex is important for hTK gene regulation.

• Korean Journal of Mathematics
• /
• v.21 no.1
• /
• pp.55-62
• /
• 2013

The base $l(S)$ of a signed digraph S is the maximum number $k$ such that for any vertices $u$, $v$ of S, there is a pair of walks of length $k$ from $u$ to $v$ with different signs. A graph can be regarded as a digraph if we consider its edges as two-sided arcs. A signed cyclic graph $\tilde{C_n}$ is a signed digraph obtained from the cycle $C_n$ by giving signs to all arcs. In this paper, we compute the base of a signed cyclic graph $\tilde{C_n}$ when $\tilde{C_n}$ is neither symmetric nor antisymmetric. Combining with previous results, the base of all signed cyclic graphs are obtained.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
• /
• 1998.06a
• /
• pp.407-410
• /
• 1998

During the past decade, substantial research effort has been directed into the development of rechargeable lithium batteries. Although some improvements in cycle life and efficiency have been achieved, the reversibility of the lithium electrode remains as a significant problem in aprotic solvent based electrolyte. The major problems limiting cycle life are short circuits resulting from growth of lithium dendrites, and macroscopic shape changes during the recharge process. As an anode material of lithium rechargeable battery, amorphous carbon materials have been studied extensively because of their high electrochemical performance. The polyacene materials prepared from phenol refine at relatively low temperature(550∼750$^{\circ}C$) show a highly Li-doped state up C$_2$Li state without liberation of Li cluster. So it has largely layered distance 4${\AA}$. The Li storage mechanism as well as the large hysterisis observed in the voltage-capacity profile of the amorphous carbone materials are still the subjects of controversy. We prepared each polyacene material various temperature and investigated electrochemical property. The mole ratio of [H]/[C] is 0.027∼0.015 range.