• 한국세라믹학회지
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• 제32권6호
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• pp.659-668
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• 1995

Zirconium carbide was prepared from the mixture of metal zirconium and carbon powders in argon atmosphere by Self-propagating High-temperature Synthesis (SHS) in order to obtain the best carbon source and dilution contents. The most exellent result was obtained in the case that active carbon was added as a starting material, 20~30 wt% dilution content. From thermal profile analysis an apparent activation energy of 118 KJ/mol was calculated. The maximum heating rate achieved during 15 wt% ZrC reaction by product dilution method was approximately 1.54$\times$105 K/s. Coupling this value with the measured wave velocity of 1.026cm/s yielded a maximum thermal gradient fo $1.5\times$105 K/cm. Using the definition of t* and the measured wave velocity, the effective thermal diffusivity, $\alpha$, was calculated to be 0.62$\times$102 $\textrm{cm}^2$/s.

• Mass Spectrometry Letters
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• 제1권1호
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• pp.29-32
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• 2010

Cross reacting antibodies can cause an overestimation of the results of immunoassays. Therefore, alternative methods are needed for the accurate quantification of steroids. Gas chromatography combined with isotope-dilution mass spectrometry (GC-IDMS) is developed to quantify urinary active androgens, testosterone, epitestosterone and dihydrotestosterone, which are clinically relevant androgens to both hair-loss and prostate diseases. The method devised involves enzymatic hydrolysis with $\beta$-glucuronidase, solid-phase extraction, liquid-liquid extraction using methyl tert-butyl ether and subsequent conversion to pentafluorophenyldimethylsilyl-trimethylsilyl (flophemesyl-TMS) derivatives for sensitive and selective analysis in selected-ion monitoring mode. Flophemesyl-TMS derivatization not only eliminates matrix interference but also has a good peak resolution within a 6 min-run. A selective and sensitive GC technique with flophemesyl-TMS derivatives also allows accurate quantitative analysis of three active androgens when combined with IDMS. The limit of quantification of the three analytes was <50 pg/mL, and extraction recoveries ranged from 91.9 to 102.1%. The precision and accuracy were 1.2~6.5% and 89.0~106.7%, respectively. This GC-IDMS method can be useful for evaluating the drug efficacy and monitoring the biological processes responsible for male-pattern baldness and prostate diseases.

• Bulletin of the Korean Chemical Society
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• 제31권11호
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• pp.3228-3232
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• 2010

Malachite green (MG) has been used world-widely in aquaculture as a parasiticide or fungicide. Although MG performed successfully, it has not been permitted for use in aquaculture from European Union, USA, and Canada because of its carcinogenicity and mutagenicity. We developed a sensitive and specific method to determine MG and its principal metabolite, leucomalachite green (LMG), respectively by isotope dilution liquid chromatography mass spectrometry (ID-LC/MS). To enhance the extraction recovery of MG and LMG from fish tissue, an additional step, saponification, was introduced in sample preparation process to remove fat in sample extract, which hampered the performance of SPE columns. The residue of MG and LMG in fish was analyzed using liquid chromatography mass spectrometry in the selected ion monitoring (SIM) mode by monitoring at m/z 329 and 334 for MG and $d_5$-MG and at m/z 331 and 337 for LMG and $^{13}C_6$-LMG, respectively. This method was validated by comparing with the value of the reference material provided by Laboratory Government Chemistry (LGC). The results agreed within the measurement uncertainty and the accuracy was much improved than the provided reference value by LGC.

• 한국안전학회지
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• 제15권3호
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• pp.30-39
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• 2000

The present paper deals with the numerical simulation for the spray characteristics with swirling turbulent flows and dilution flows from swirl injectors in a simplified can type of gas turbine combustor. The main objective is to investigate the characteristics of swirling turbulent flows with dilution flows and to provide the qualitative results for the spray characteristics such as the droplet distribution and Sauter Mean Diameter(SMD). The gas-phase equations based on Eulerian approach were discretized by Finite Volume Method, together with SIMPLE algorithm and the Reynolds -Stress-Model. The liquid-phase equations based on Lagrangian method were used to predict the droplet behavior. The results of preliminary test are generally in good agreement with experimental data, and show that the anisotropy exists in the primary zone due to swirl velocity and injected air from primary injector, and then gradually decays due to turbulent mixing and consequently near-isotropy occurs in the region between primary and dilution zones. For the spray characteristics, it is indicated that the swirling flows of primary jet region increase the droplet atomization. In addition, it is showed that the swirling flows at the inlet region lead the air-fuel mixture to be distributed near the igniter and can significantly affect the spray behavior in the primary jet region.

• 한국물환경학회지
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• 제30권5호
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• pp.512-516
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• 2014

Two different methods for TOC (Total Organic Carbon) analysis of livestock manure including high strength solid organics were evaluated. Firstly, an analyzing method by dilution after pre-treated by Ultrasonicator and 100 mesh sieve for homogenization was defined as TOC 1; and secondly method divided by particulate organic carbon (POC) and dissolved organic carbon (DOC) was defined as TOC 2. 116 samples collected from 56 farms were analyzed in TOC1, TOC2, BOD and VSS. TOC1 method showed higher accuracy at less than 30,000 mg/L of TOC while TOC2 method presented significant reliability at over that concentration. Regarding to the sample with the same VSS concentration, the correlation between TOC 2 and VSS (${\rho}$: 0.806) was slightly higher than that between TOC 1 and VSS (${\rho}$: 0.784), resulted from a relatively low loss of solids and a low error probability (dilution and homogenization effects) in the analyzing procedures. In addition, the reliability between POC and VSS in TOC2 was high and the POC was about 4.4 fold that of the VSS. Consequently, TOC 2 without dilution effect was assessed as a proper method to increase the analyzing accuracy of swine manure including high solid organics.

• 전기의세계
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• 제28권12호
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• pp.27-32
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• 1979

13명의 환자에 있어서 새로운 비관혈적 방법에 의한 심박출량을 계산하고, 열희석에 의한 방법으로 측정한 심박출량과 비교하였다. 본 논문에서 사용한 비관혈적 펄스 전달 방법은 대동맥 모델에서의 최적 매개변수 방법을 사용하였다. 모델의 최적 매개변수는 맥압의 첫번째 고주파 전달함수에서 측정치와 계산치의 차이를 최소화하는 조건에 의하여 계산하였다. 전달함수의 2개의 펄스는 각각 경동맥동과 대퇴동맥에서 Piezo-resistive Pulse Microphone을 사용하여 측정하였고, 대동맥의 직경은 초음파 방법을 사용하여 측정하였다. 13명의 환자에게서 16가지 측정을 해서 열희석과 비관혈적 방법은 0.89의 상관계수를 보여주었다.

• 대한미생물학회지
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• 제22권3호
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• pp.301-307
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• 1987

A total of 42 strains of Candida albicans were examined for susceptibility to three antifungal agents, amphotericin B(AMB), 5-fluorocytosine(5-FC), and ketoconazole(KTZ), using defined medium, synthetic amino acid medium-fungal(SAAM-F), supplemented yeast nitrogen base(SYNB) and undefined medium Sabouraud's dextrose broth(SDB) and Kimmig broth media. A tube dilution method was used with minimum inhibitory concentrations(MICs) determined after incubation for 24 hour and 48 hours. All testes were performed in duplicate. In general, MICs were more reproducible after 48 hour of incubation. Forthermore, MICs determined after incubation for 48 hours were significantly higher than those determined after 24 hours. The actural MICs obtained with the different antifungal agents were clearly influenced by the test medium used. The rank order of AMB MICs according to the test medium was as follows: SAAM-F>SYNB>SDB>Kimmig broth. With 5-FC, the following pattern was observed: SYNB>SAAM-F>SDB>Kimmig borth. For ketoconazole, the MICs according to the test medium was SAAM-F>SDB>SYNB> Kimmig broth. In amphotericin B, the MICs mean value with the test medium was as follows: SDB, 0.24 mcg/ml; Kimmig broth, 0.29 mcg/ml; SYNB, 0.21 mcg/ml and SAAM-F, 0.15mcg/ml. The actural value of 5-FC was; SDB, 37.20 mcg/ml; Kimmig broth, 67.41mcg/ml; SYNB, 21.29 mcg/ml and SAAM-F, 24.61 mcg/ml and in ketoconazole, the MICs value was; SDB, 1.83 mcg/ml; Kimmig broth, 4.08 mcg/ml; SYNB, 1.95 mcg/ml and SAAM-F, 1.41 mcg/ml. The results of this investigation suggested that broth dilution susceptibility testing of yeast and yeast-like fungi are best performed with an incubation period of 48 hours. Furthermore, medium composition can significantly influence the results of such testing.

• 분석과학
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• 제16권6호
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• pp.450-457
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• 2003

사용후핵연료 내 U 및 동위원소 정량분석을 동위원소 희석 질량분석법 (isotope dilution mass spectrometry, IDMS)으로 수행하였다. 시료는 산화우라늄 사용후핵연료 시료를 $HNO_3$(1+1) 또는 이 용액과 14 M $HNO_3-0.05M$ HF 혼합용액으로 용해한 후 막 거르게 ($1.2{\mu}m$)로 여과하여 준비하였다. 시료 및 스파이크를 첨가한 시료 중의 U은 AG lX8 음이온교환 수지관에서 0.1 M HCl 용액으로 용리하였다. 시료 중의 총 U 량과 성분 동위원소 ($^{234}U$, $^{235}U$, $^{236}U$ 및 $^{238}U$)의 조성은 $^{233}U$을 스파이크로 이용하는 동위원소 희석 질량분석법으로 정량하였다. 제조한 U-233 스파이크 용액은 천연 및 감손 U을 이용한 역동위원소 희석 질량분석법 (reverse isotope dilution mass spectrometry, R-IDMS)으로 표정하였다. 동위원소 희석 질량분석법에 의한 핵연료시료 중의 총 U 량 측정결과를 전위차 적정으로 측정한 결과와 비교하였을 때 0.34% 평균 상대오차 범위에서 일치하였다.

• 분석과학
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• 제12권6호
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• pp.550-557
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• 1999

본 연구에서는 209종의 PCBs 이성체중 독성등가계수(Toxic Equivalance Factor, TEF)가 제시된 13종의 toxic-PCBs에 대하여 Isotope dilution HRCC/HRMS 방법으로 저니토중의 toxic-PCBs를 분석하였다. 분석결과 surrogate 표준물질의 회수율은 71~99%로 양호하였다. 13종의 toxic-PCBs 농도는 0.84~2.49 ng/g 범위이었으며, 이중 2,2',3,3',4,4',5-HpCB(IUPAC No. 170) 및 2,2',3,4,4',5,5'-HpCB(IUPAC No. 180) 농도가 전체 농도의 50% 정도를 나타내었으며, 2,3,4,4,5-PeCB(IUPAC No. 114)도 10% 정도를 나타내었다. 독성등가계수로 환산한 농도는 0.38~2.63 pg-TEQ/g 범위이었으며, 3,3',4,4',5-PeCB(lUPAC No. 126)가 전체의 50%를 나타내었다.

• Journal of Radiation Protection and Research
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• 제23권1호
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• pp.1-6
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• 1998

영광 원전 지역에 적용될 수 있는 액체 방사성 물질의 확산 모델을 개발하였다. 영광에서의 해양 확산 조건은 매우 복잡하기 때문에 수치적 모델을 적용하는 것은 매우 어렵다. 따라서 비교적 단순하면서도 신뢰성 있는 미규제 지침 1.113에서 제시한 통계적 모델을 적용하였다. 이를 통해, 발전소 운전 조건이나, 피폭 경로에 따른 희석 인자를 계산할 수 있는 컴퓨터 코드를 개발하였다. 액체 방사성 물질의 확산에 대해서, 혼합 범위에 따라 근거리 혼합 모델과 원거리 혼합 모델로 구분하여 모델을 개발하였다. 근거리 혼합 현상은 부력과 초기 운동량 및 난류에 의해 결정된다. 원거리 혼합에서는 대기 중의 구름 확산과 유사하게 가우시안푸륨 모델을 적용할 수 있다. 서로 다른 피폭 경로에 대해 물리적으로 타당한 적분을 수행함으로서, 경로에 따른 희석 인자를 구할 수 있었다. 개발된 모델을 사용하여 계산한 결과에 의하면, 현행 영광 ODCM에 사용되는 희석 인자는 상당히 과평가되어 있음을 알 수 있다.