• 약학회지
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• 제44권6호
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• pp.595-600
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• 2000

Transdermal delivery of ketorolac tromethamine, a potent non-narcotic analgesic, through human cadaver skin was investigated in vitro. A mixture of ethanol/water (40/60) containing 0, 1, 3, 5, and 8 (w/v)% L-menthol were used as a vehicle and penetration enhancer respectively. The permeation of ketorolac through human cadaver skin from saturated drug solution was evaluated at $37^{\circ}C$ with modified Franz diffusion cell. The in vitro skin flux and lag time were $1.23\;{\pm}\;0.11\;{\mu}g/cm^2{\cdot}hr$ and $5.56\;{\pm}\;0.34\;hr$, respectively. The cumulative amount of penetrated ketorolac containing L-menthol in ethanol/water (40/60) binary system was increased by the following order; 3%, 5%, 8%, 1%, 0%, and the lag time was decresed by the following order; 3%, 5%, 8%, 0%, 1%. The results suggested that a potential use of 3% L-methol is an effective penetration enhancer of ketorolac tromethamine through the human cadaver skin.

• 한국태양에너지학회 논문집
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• 제24권2호
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• pp.39-50
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• 2004

One of the challenge for successful daylighting design might be to capture sunlighting that varies in both intensity and position and to deliver the luminous flux into the inner space as deep as possible. Conventional glazing apertures allow daylight in the outer 3.5m of a perimeter spaces. More advanced daylighting technologies can extend this daylighting depth by reflecting sunlight further from the windows within a deep floor area. For this purpose, this study developed light shelves based on performance evaluation with a mock-up model that constructed recently and measured under real sky condition. All these daylighting devices have a customized geometry developed from the solar path at a given latitude and utilize unique reflecting finishing to maximize the amount of redirection and diffusion of the daylight. This paper tells that the best daylighting penetration typically can be expected from using light-colored sloped external shelves.

• 한국진공학회지
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• 제4권2호
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• pp.194-200
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• 1995

2-3nm의 공간분해능을 갖는 전자에너지손실분광법(Electron Energy Loss Spectroscopy, EELS)을 이용하여, 전기적 특성조사된 YBa2Cu3O7-$\delta$ 고온초전도체 쌍결정의 결정경계(grain boundary)에서 산소의 조성변화를 조사하였다. Misorientation angle이 $14^{\circ}$, $28^{\circ}$,$ 30^{\circ}$인 3개의 쌍결정 중에서 Josephson junction 특성을 보인 $28^{\circ}$ 및 $30^{\circ}$결정경계에서의 oxygen 1s absorption edge는 결정내부에서의 oxygen 1s absorption edge와 매우 다름을 알 수 있었다. 이는 결정경계에서의 산소조성이 결정내부에 비해 낮음을 의미하며, 그 영역이 결정경계 부근 20-40nm로, coherence length에 비해 큼을 알 수 있다. 반면에, flux pinningxmr성을 보인 $14^{\circ}$결정경계에서의 oxygen 1s absorption edge는 결정내부에서와 별 차이를 보이지 않았다. 따라서 일반적으로 관찰되어온, misorientation angle이 큰 결정경계에서의 Josephson junction 특성은 결정경계 부근에서 산소의 조성이 낮아지는데에 기인하며, 그 원인은 결정경계면을 통해 산소가 out-diffusion되기 때문인 것으로 생각된다.

• Journal of applied mathematics & informatics
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• 제15권1_2호
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• pp.29-51
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• 2004

In this paper, we propose a new mixed finite element method, called the characteristics-mixed method, for approximating the solution to Burgers' equation. This method is based upon a space-time variational form of Burgers' equation. The hyperbolic part of the equation is approximated along the characteristics in time and the diffusion part is approximated by a mixed finite element method of lowest order. The scheme is locally conservative since fluid is transported along the approximate characteristics on the discrete level and the test function can be piecewise constant. Our analysis show the new method approximate the scalar unknown and the vector flux optimally and simultaneously. We also show this scheme has much smaller time-truncation errors than those of standard methods. Numerical example is presented to show that the new scheme is easily implemented, shocks and boundary layers are handled with almost no oscillations. One of the contributions of the paper is to show how the optimal error estimates in $L^2(\Omega)$ are obtained which are much more difficult than in the standard finite element methods. These results seem to be new in the literature of finite element methods.

• 대한기계학회논문집B
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• 제22권4호
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• pp.499-509
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• 1998

In the absorption process of water vapor in a liquid film, the composition of the gas phase, in which a non-absorbable gas is combined with the absorbate influences the transport characteristics remarkably. In the present study, the absorption processes of water vapor into aqueous solution of lithium bromide in the presence of non-absorbable gases were investigated analytically. The continuity, momentum, energy and diffusion equations for the solution film and gas phase were formulated in integral forms and solved numerically. It was found that the mass transfer resistance in gas phase increased with the concentration of non-absorbable gas. However the primary resistance to mass transfer was in the liquid phase. As the concentration of non-absorbable gas in the absorbate increased, the liquid-vapor interfacial temperature and concentration of absorbate in solution decreased, which resulted in the reduction of absorption rate. The reduction of mass transfer rate was found to be significant for the addition of a small amount of non-absorbable gas to the pure vapor, especially at the outlet of an absorber where non-absorbable gases accumulated. At higher non-absorbable gas concentration, the decrease of absorption flux was almost linear to the volumetric concentration of non-absorbable gas.

• 대한기계학회논문집
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• 제19권5호
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• pp.1300-1307
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• 1995

The effect of thermal stratification on the turbulent dispersion from a fine cylindrical heat source was experimentally examined in a wind tunnel with and without a strong temperature gradient. A 0.5 mm dia. nichrome wire was used as a line heat source. Turbulent intensities, r.m.s. value of temperature and convective heat fluxes were measured by using a hot-wire and cold-wire combination probe. The results show that the peack value and the spread of the vertical turbulent intensity for the stratified case are far lower than those in the neutral case, which indicates that the stable temperature gradient suppresses the vertical velocity component. All of the third order moments including heat fluxes measured in the stable condition have very small values than those of the neutral case. This nature suggests that the decrease of scalar fluctuations in the stably stratified flow is mainly due to the suppression ofthe turbulent diffusion processes by the stable stratification. A simple gradient model with a composite timescale which has a simple weighted algebraic mean between dynamic and thermal time scale yields reasonably good numerical values in comparison with the experimental data.

• 설비공학논문집
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• 제2권3호
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• pp.243-255
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• 1990

The objective of this study is to present an efficient measurement method of the effective thermal diffusivity for the fibrous insulation material. The non-linear parameter estimation (NPE) method is adapted for this analysis because of its accuracy and its results are compared with those by other direct methods such as CTP, CHP and STD method. A experimental system is constructed with bell-jar vaccum chamber, diffusion pump, tube type furnace, control unit and data acquisition system included with A/D converter and IBM XT/AT personal computer. The typical results obtained from this study are as follows; 1) NPE method can be recommended as an useful and accurate method to measure the effective thermal diffusivity of insuation material because it is shown that the measurement error compared with those by other direct methods is reduced for standard material, NBS-1450b. 2) NPE method can minimize the effects of ill-measured temperature due to external disturbance, because the final value is found by point to point estimating. 3) NPE method dose not depend on the kinds of heat flux, since the surfac temperature are used to estimate the thermal diffusivity. 4) With NPE method, compared with the steady state method, a measuring time and a sample size could be reduced.

• Membrane and Water Treatment
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• 제8권5호
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• pp.437-448
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• 2017

A high quality Na-X zeolite membrane was synthesized on a seeded ${\alpha}-alumina$ disc by the secondary growth method. Structural characterization was done by X-ray spectroscopy, FT-IR spectroscopy, SEM and AFM imaging. The performance evaluation of the membrane was firstly tested in separation of glucose/water solutions by pervaporation process. There was obtained a separation factor $182.7{\pm}8.8$, while the flux through the membrane was $3.6{\pm}0.3kg\;m^{-2}\;h^{-1}$. The zeolite membrane was then used for desalination of aqueous solutions consisting of $Na^+$, $Ca^{2+}$, $Cs^+$ and $Sr^{2+}$ because of the importance of these ions in water and wastewater treatments. The effects of some parameters such as temperature and solution concentration on the desalination process were studied for investigating of diffusion/adsorption mechanism in membrane separation. Finally, high water fluxes ranged from 2 up to $9kg\;m^{-2}\;h^{-1}$ were obtained and the rejection factors were resulted more than 95% for $Na^+$ and $Ca^{2+}$ and near to 99% for $Cs^+$ and $Sr^{2+}$. Based on the results, fluxes were significantly improved due to convenient passage of water molecules from large pores of NaX, while the fouling was declining dramatically. Based on the results, NaX zeolite can efficiently use for the removal of different cations from wastewaters.

• 대한기계학회논문집B
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• 제27권7호
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• pp.883-892
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• 2003

The experiment using three-dimensional laser Dopperr velocimetery (LDV) measurements and the computation using the Reynolds stress model of the commercial code, FLUENT, were conducted to give a clear understanding on the structure of tip leakage flow in a forward-swept axial-flow fan operating at the maximum efficiency condition. The tip leakage vortex was generated near the position of the minimum wall static pressure, which was located at approximately 12% chord downstream from the leading edge of blade suction side, and developed along the centerline of the pressure trough within the blade passages. A reverse flow between the blade tip region and the casing, induced by tip leakage vortex, acted as a blockage on the through-flow. As a result, high momentum flux was observed below the tip leakage vortex. As the tip leakage vortex proceeded to the aft part of the blade passage, the strength of tip leakage vortex decreased due to the strong interaction with the through-flow and casing boundary layer, and the diffusion of tip leakage vortex caused by high turbulence. In comparison with LDV measurement data, the computed results predicted the complex viscous flow patterns inside the tip region, including the locus of tip leakage vortex center, in a reliable level.

• Ocean and Polar Research
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• 제34권3호
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• pp.287-296
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• 2012

In the theory of source-driven abyssal circulation, the forcing is usually assumed to be steady source (deep-water formation). In many cases, however, the deep-water formation occurs instantaneously and it is not clear whether the theory can be applied well in this case. An attempt is made to resolve this problem by using a simple reduced gravity model. The model basin has large depth change compared for its size, like the East Sea, such that isobaths nearly coincide with geostrophic contours. Deep-water is formed every year impulsively and flows into the model basin through the boundary. It is found that the circulation driven by the impulsive source is generally the same as that driven by a steady source except that the former has a seasonal fluctuation associated with unsteadiness of forcing. The magnitudes of both the annual average and seasonal fluctuations increase with the rate of deep-water formation. The problem can be approximated to that of linear diffusion of momentum with boundary flux, which well demonstrates the essential feature of abyssal circulation spun-up by periodic impulsive source. Although the model greatly idealizes the real situation, it suggests that abyssal circulation can be driven by a periodic impulsive source in the East Sea.