• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2185-2191
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• 2012

Background: Prevalence of Barrett's esophagus (BE) in Luoyang, China, has not been reported, and its pathogenesis is controversial. The aim of this study was therefore to investigate the prevalence of BE and its underlying factors in the city of Luoyang. Method: This was a prospective study in one center. Many patients were analyzed using endoscopy who showed upper gastrointestinal symptoms between August 2006 and June 2007. In addition, the effect of apoptosis-related proteins and heat shock proteins upon BE's pathogenesis were also investigated by an immunohistochemical protocol. Results: Prevalence of BE was at 4.55% and the mean age of those affected was about 10 years older than for esophagitis. Typical reflux symptoms were significantly lower than with esophagitis, whereas signs of caspase-3 and HSP105 elevation were significantly higher. Expression of TERT, HSP70 and $HSP90{\alpha}$ in BE cases was significantly lower than in esophagitis. However, there was no statistical difference between the two groups in expression of HSP27. Conclusions: The prevalence of BE is high in Luoyang, which could result from esophagitis despite typical reflux symptoms being relatively uncommon. Initiation and development of BE might be the result of accelerated proliferation, apoptosis and differentiation of original cells to intestinal epithelium.

• Journal of Veterinary Clinics
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• v.22 no.1
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• pp.70-73
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• 2005

A 9-year old female Shih Tzu dog was presented to the Veterinary Medical Teaching Hospital of Seoul National University with a history of chronic intermittent anorexia and vomiting of 4-year duration. She visited 3 years ago with the same clinical signs but has not been treated regularly due to waxing-waning course. On the physical examination, no specific findings were found. CBC, serum chemistry, radiography, ACTH stimulation test, evaluation of serum T4 and TSH concentration were performed. Hypoadrenocorticism was diagnosed with the ACTH stimulation test. And then, secondary hypoadrenocorticism was diagnosed with ACTH stimulation test, pre-ACTH aldosterone concentration, endogenous ACTH concentration. As electrolyte concentrations were normal, glucocorticoid (0.15 mg/kg bid PO) alone was administered. She has recovered from the clinical signs and has been doing well. It is suggested that the differentiation of secondary hypoadrenocorticism from primary hypoadrenocorticism is important as the secondary hypoadrenocorticism occurs rarely and the symptoms are non-specific with normal electrolyte concentrations.

• Imaging Science in Dentistry
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• v.30 no.2
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• pp.138-143
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• 2000

The osteochondroma, also known as osteocartilagenous exostosis, is one of the most common benign tumors of the axial skeleton, but is rarely found in the facial bones. When present, the tumor is most often reported to affect the mandibular coronoid process. Osteochondroma of the mandibular condyle is extremely rare and may cause signs and symptoms like those seen in patients with temporomandibular joint dysfunction. Sometimes, differentiation between osteochondroma and condylar hyperplasia is not possible on histologic grounds alone, but the radiographic and intraoperative findings together are usually sufficient to establish a definite diagnosis. This report reviews the literature concerning osteochondroma, especially of the maxillofacial region, and describes a case of osteochondroma of the condyle.

• Childhood Kidney Diseases
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• v.19 no.2
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• pp.118-124
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• 2015

Purpose: The symptoms and signs of urinary tract infection (UTI) in early infancy are non-specific. Prompt diagnosis of UTI is important, as untreated UTI results in renal damage. Especially, febrile UTI in young infants coexist with other serious bacterial infections. The purpose this study was to propose modified Rochester criteria to differentiate viral infection from urinary tract infection. Methods: We carried out a retrospective investigation of 168 infants less than three months old with a tympanic temperature $>38^{\circ}C$ who were admitted to Chung-Ang University Hospital between 2011 and 2014. We compared the symptoms, physical examination results, and laboratory data between viral infection and UTI groups. A modified Rochester criterion was composed of statistically significant factors. Results: A total of 76 and 92 infants with UTI and a viral infection, respectively, were included. Statistically significant differences in gender, previous admission history, neutrophil ratio, and urine WBC count were found between the two study groups. Using a cut off value of 3 points, the sensitivity and specificity of the modified Rochester criteria were 71.28% and 78.57%, respectively. Conclusion: The modified Rochester criteria may give an outline for identifying young infants with UTI.

• The Journal of Korean Medicine
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• v.15 no.2 s.28
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• pp.132-142
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• 1994

Paraquat has been widely used as a herbicide in Korea since 1970. Human ingestion results in transient impairment of liver and kidney function and a characteristically respiratory failure with a high mortality rate. Clinical investigation and Oriental Medical Treatment were done on 3 cases of paraquat poisoning admitted to the department of 1st Internal Medicine. Kyung San University Oriental Medical Hospital from August 1991 to December 1992. and following results were obtained. The symptoms of paraquat poisoning can be regarded as Sim hua chi song(心火熾盛), Kan hua sang yom(肝火上炎). um hu hua wang(陰虛火旺), Kan tam sup yol(肝膽濕熱), Yang myong yol tok(陽明熱毒) in Oriental Medicine. and the principle of treatment for paraquat poisoning can be applicable to Chong yol Ii sop(淸熱利濕), Chong yol hae tok(淸熱解毒). Sa ha hae tok(瀉下解毒). Ja um kang hua(滋陰降火) and so on. Three cases were treated by HuangYonHaeTokTang(黃蓮解毒湯) and KamDuTang(甘豆湯): all of them have survived without complications. According to the result above, it suggests that determination of treatment based on the differentiation of symptoms and signs(Pyon jung si chi ;辨證施治) of Oriental Medicine may prove to be helpful in saving lives of patients with paraquat poisoning.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.2 s.33
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• pp.230-239
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• 2007

Introduction : Atopic dermatitis is very epidermic disease in these days. Atopic dermatitis is difficult for patient to be treated because there is no specific treatment. The oriental method of atopic dermatitis is varied as patient situation and doctor's view point. The Treatise on Febrile Diseases(傷寒論) may be a hint for atopy disease. Object: Although we use various method such as acupucture, aroma therapy, a medicine for external use, we use the two decoctions in the Treatise on Febrile Diseases according to differentiation of syndromes and abdominal diagnosis. Result : After inpatient treatment in 21 days, the itching, redness, exudation, crust, lichen get better and insomnia and constipation was removed quickly. The SCORAD index is decreased from 84.2 to 25.9. Conclusion : These decoction can treat the atopic dermatitis although there is no symptom in atopy because we cure the all situation of the patient. We can cure the atopic dermatitis not only by routine remedy for various symptoms but also by diagnosis and treatment based on overall analysis of symptoms and signs.

• The Journal of Korean Medicine
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• v.15 no.2 s.28
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• pp.321-333
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• 1994

1. Autum-dryness syndrome(秋燥) is caused by dry-warm or dry=-cool weather condition when lower-warmer Eumfen(下焦陰分) was injured by jung hyoul hatal(精血下脫) or taking medicines of dryness in autumn. 2. The symptoms of autum-dryness syndrome are headach, fever, chilling, anhydrosis, dry cough, tinnitis, dry lip, dry skin, chest discomfort in cool-dryness syndrome(凉燥) and headach, fever, dry cough, paroxymal cough, dry skin, chest pain, polydipsia, tinnitis, eye redness, sore throat in heat-dryness syndrome(溫燥). 3. Hyangsochongsitang(香蘇蔥頭湯) chn be applied for terating cool-dryness syndrome(凉燥) and chungjogoopyetang(淸燥救肺湯) for heat-dryness syndrome(溫燥). Sang Hang Tang(桑杏湯) can be administered when the evils located in the upper-warmer, and Yukmihwan(六味丸) can be administered when located in the lower-warmer(下焦) 4. According the determination of treatment based on the differentiation of symptoms and signs. When the symptoms of Weifen syndrome(衛分證) are headach, fever, dry lip or chilling or dypsia and the treatment of weifen syndrome apply Hangsosan(行蘇散) or Sang hang tang(桑杏湯). When the symptoms of Qifen syndrome(氣分證) are tinnitis, eye redness, sore throat, chest discomfort, polydipsia, dry cough, watery diarrhea, constipation and Jibaekjihwang(知栢地黃丸) when Ohingulpitang(五仁橘皮湯) Chungjogupyetang(淸燥救肺湯) can are applied for treating Qifen syndrome(氣分證). When the symptoms of younghylfen syndrome(營血分證) are dry cough, watery diarrhea, dypsia, chest discomfort, hematemesis, epistaxis and agyohwang keum tang(阿膠湯) Oknyujun(玉女煎) can be applied for treating Younghyulfen syndrome(營血分證).

• The Journal of Internal Korean Medicine
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• v.25 no.4
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• pp.34-44
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• 2004

Objective : The purpose of this study is to investigate clinical characteristics with 25 patients who have suffered from headache and were treated. Methods : We classified 25 patients into several groups by IHS classification and evaluated the effects of oriental medical therapy on headache. Results : 1. According to the statistics, instances of migraine were more prevalent than tension headache, especially among women. 2. 28% of patient had entered for treatment within one month of onset. 3. Common associated symptoms included dizziness, nausea, dyspepsia, palpitation and insomnia. 4. In classification by the oriental medical differentiation of symptoms and signs, the rate of stagnation of the humid dam and deficiency of qi, these two types were highest. 5. 56% of patients said they were satisfied with the treatment, reporting half the frequency of headache or better from before treatment. Conclusions : The present results suggest that oriental medical therapy has effects on headache. Further clinical comparative studies on herb-medication versus acupuncture therapy for headache are urged.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.6
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• pp.1368-1373
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• 2008

This study was done to calculate the specific indicators of Fire-Heat Pattern Identification and Yin Deficiency Pattern Identification settled by tentative Korean Standard Differentiation of the Symptoms and Signs for Stroke. The subjects were 764 hospitalized patients with stroke, and a list of registry was made for each of them. Frequency and Correlations among Fire-Heat and Yin Deficiency indicators were studied. Fire-Heat pattern group included 175 patients out of 764, Yin Deficiency pattern group included 103 patients out of 764. Among the indicators of Fire-Heat pattern, those, in order of highest frequency, were 'heat vexation and aversion to heat', 'reddened complexion', 'thirst'. Among the indicators of Yin Deficiency pattern, those, in order of highest frequency, were 'dry mouth', 'red tongue', 'fine and rapid pulse'. Among the Fire-Heat pattern indicators, 'yellow fur' and 'thirst', 'heat vexation in the chest' and 'vexation and insomnia' showed most significant correlation. Among the Yin Deficiency pattern indicators, 'aphtha or tongue sore' and 'heat in the palms and soles', 'red tongue' and 'dry fur' showed most significant correlation. 'Reddened complexion', 'dry eyes', 'surging and parid pulse', 'heat vexation and aversion to heat' are classify between Fire-Heat pattern and Yin Deficiency pattern. 'Surging and parid pulse', 'Reddened complexion' are mostly representative of Fire-Heat pattern and 'fine and rapid pulse' are mostly representative of Yin Deficiency pattern.

• The Journal of Korean Medicine
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• v.28 no.3 s.71
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• pp.126-137
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• 2007

Objectives : Standardization of pattern identification for stroke and development of a diagnostic tool for Korean medicine. Methods : We organized a committee for stroke diagnosis standardization of Korean traditional medicine and submitted the Korean standard differentiation of the symptoms and signs for stroke (KSDSS). We collected cases through a multi-center network consisting of twelve university hospitals and one local hospital. We analyzed the data with discriminant function and logistic regression. Results : 321 cases were confirmed by diagnosis of medical specialists and residents. They were divided into qi deficiency 30.84%, dampness & phlegm 25.55%, fire & heat 22.43%, eum deficiency 18.69% and blood stasis 2.49%. The accordance rate between discriminant function and doctor's diagnosis was calculated. Conclusions : To make a stroke diagnostic program, we must raise the accordance rate between doctor's diagnosis and the program.