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Lipid Composition of Roe, Muscle and Viscus of Liza Carinata, a Species of the Mugilidae Family (등줄숭어의 알, 근육 및 내장의 지질조성에 관한 연구)

  • Joh, Yong-Goe;Lee, Kyeng-Hee;Cho, Yon-Joo
    • Korean Journal of Food Science and Technology
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    • v.20 no.5
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    • pp.674-682
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    • 1988
  • Total lipids from the roe, muscle and viscus of L. carinata were analyzed for lipid composition by column chromatography, thin-layer chromatography and gas-liquid chromatography. The roe lipids were characterized by a high level of wax esters (63.1%) and a low proportion of trigiycerides (9.9%). The viscus lipids also contained wax esters (32.8%) as its main component, followed by free fatty alcohols and acids (23.5%). On the other hand, the muscle lipids were found to contain a large amount of triglycerides (66.1%) with a trace of wax esters. The main fatty alcohol component of roe and viscus wax esters was C16:0 alcohol (53.0%; 61.7%), accompanied by C18:1 alcohol (10.2%) in the former and by C15:0 alcohol (8.8%) in the latter. Considerable amounts of odd-numbered fatty alcohols were found in both wax esters. On the other hand, the fatty acids of the roe and viscus wax esters contained a high percentage of monounsaturated (49.7%-56.6%) consisting of C16:1, C18:1 and C17:1 acid, and a significant amount of polyunsaturated (41.2%-32.9%), particularly C20:5${\omega}$3. The fatty acid components of triglycerides and phospholipids were different among the tissues tested, especially between roe and muscle or viscus. The fatty acid compositions of free fatty acids from the muscle and viscus were characterized by a higher level of polyunsaturated fatty acids (46.0-34.3%) compared to those of triglycerides 'in the roe, muscle and viscus (28.4%, 19.4% and 19.2%).

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Pollutant Contents with Particle Size Distribution in Bridge Road Drainage Sediment (교량도로 배수받이 퇴적물질의 입경별 오염물질 함량)

  • Lee, Jun-Ho;Cho, Yong-Jin;Bang, Ki-Woong
    • Journal of Korean Society of Environmental Engineers
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    • v.29 no.12
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    • pp.1360-1365
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    • 2007
  • The purpose of this study is to present the basic data for nonpoint pollutant loads from bridge road drainage sediments using the results to analyze organic matter and heavy metals from the four bridge drainage sampling sites with sediments of different particle size ranges. The sediment sample was collected from the bridge road drainage and the masses of nine sediments fractions were obtained after drying the separated sediment in an over at $85^{\circ}C:>2,000{\mu}m$, $1,000\sim2,000{\mu}m$, $850\sim1,000{\mu}m$, $425\sim850{\mu}m$, $212\sim425{\mu}m$, $125\sim212{\mu}m$, $90\sim125{\mu}m$, $75\sim90{\mu}m$, $<75{\mu}m$. The sediment extract was analyzed water quality constituents, including chemical oxygen demand(COD), total nitrogen(T-N), total phosphorus(T-P), heavy metals and particle size distribution. The results indicate that most of particle size ranges of the bridge road sediments was $125\sim425{\mu}m$, and portion of $<75{\mu}m$ was low. But most of the pollutants are associated with the finer fractions of the load sediments. As the results of analysis, the range and average values of COD, T-N, T-P, Fe, Cu, Cr, and Pb were $177\sim198.8$ mg/kg(77.6 mg/kg), $23\sim200$ mg/kg(83 mg/kg), T-P $18\sim215$ mg/kg(129 mg/kg), and $1,508\sim5,612$ mg/kg(3,835 mg/kg), $9.2\sim69.3$ mg/kg(49 mg/kg), $19.1\sim662.2$ mg/kg(214 mg/kg), and $28.4\sim251.4$ mg/kg(114 mg/kg), respectively. The relationship between sediment size and pollutants concentration have an inverse proportion. The removal of road sediments with frequently could be reduced the significant nonpoint pollutant load, because of the bridge road sediment contains considerable micro-particles and heavy metals.

Social Network Analysis for the Effective Adoption of Recommender Systems (추천시스템의 효과적 도입을 위한 소셜네트워크 분석)

  • Park, Jong-Hak;Cho, Yoon-Ho
    • Journal of Intelligence and Information Systems
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    • v.17 no.4
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    • pp.305-316
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    • 2011
  • Recommender system is the system which, by using automated information filtering technology, recommends products or services to the customers who are likely to be interested in. Those systems are widely used in many different Web retailers such as Amazon.com, Netfix.com, and CDNow.com. Various recommender systems have been developed. Among them, Collaborative Filtering (CF) has been known as the most successful and commonly used approach. CF identifies customers whose tastes are similar to those of a given customer, and recommends items those customers have liked in the past. Numerous CF algorithms have been developed to increase the performance of recommender systems. However, the relative performances of CF algorithms are known to be domain and data dependent. It is very time-consuming and expensive to implement and launce a CF recommender system, and also the system unsuited for the given domain provides customers with poor quality recommendations that make them easily annoyed. Therefore, predicting in advance whether the performance of CF recommender system is acceptable or not is practically important and needed. In this study, we propose a decision making guideline which helps decide whether CF is adoptable for a given application with certain transaction data characteristics. Several previous studies reported that sparsity, gray sheep, cold-start, coverage, and serendipity could affect the performance of CF, but the theoretical and empirical justification of such factors is lacking. Recently there are many studies paying attention to Social Network Analysis (SNA) as a method to analyze social relationships among people. SNA is a method to measure and visualize the linkage structure and status focusing on interaction among objects within communication group. CF analyzes the similarity among previous ratings or purchases of each customer, finds the relationships among the customers who have similarities, and then uses the relationships for recommendations. Thus CF can be modeled as a social network in which customers are nodes and purchase relationships between customers are links. Under the assumption that SNA could facilitate an exploration of the topological properties of the network structure that are implicit in transaction data for CF recommendations, we focus on density, clustering coefficient, and centralization which are ones of the most commonly used measures to capture topological properties of the social network structure. While network density, expressed as a proportion of the maximum possible number of links, captures the density of the whole network, the clustering coefficient captures the degree to which the overall network contains localized pockets of dense connectivity. Centralization reflects the extent to which connections are concentrated in a small number of nodes rather than distributed equally among all nodes. We explore how these SNA measures affect the performance of CF performance and how they interact to each other. Our experiments used sales transaction data from H department store, one of the well?known department stores in Korea. Total 396 data set were sampled to construct various types of social networks. The dependant variable measuring process consists of three steps; analysis of customer similarities, construction of a social network, and analysis of social network patterns. We used UCINET 6.0 for SNA. The experiments conducted the 3-way ANOVA which employs three SNA measures as dependant variables, and the recommendation accuracy measured by F1-measure as an independent variable. The experiments report that 1) each of three SNA measures affects the recommendation accuracy, 2) the density's effect to the performance overrides those of clustering coefficient and centralization (i.e., CF adoption is not a good decision if the density is low), and 3) however though the density is low, the performance of CF is comparatively good when the clustering coefficient is low. We expect that these experiment results help firms decide whether CF recommender system is adoptable for their business domain with certain transaction data characteristics.

Effectiveness and characteristics of technology transfer consortia in public R&D sector: The case of Korean TT consortia (공공연구부문에서의 기술이전컨소시엄의 효과와 특성 연구: 공공기술이전컨소시엄 사례를 중심으로)

  • Park, Jong-Bok;Ryu, Tae-Kyu
    • Journal of Korea Technology Innovation Society
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    • v.10 no.2
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    • pp.284-309
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    • 2007
  • Technology transfer (TT) consortium is an affiliation of two or more public research institutions (PRIs) that participate in a common technology transfer activity or pool their resources together, with the objective of facilitating technology transfer. Based on empirical analysis of five regional TT consortia (2002-2006) operating in Korea, this paper suggests their effectiveness by employing a TT performance index (TTPI) and identifies possible characteristics involved, such as motivations, facilitators, barriers, and challenges. TTPI devised in the paper is a new composite TT performance index to measure how much the TT performance of a PH changed in a designated year compared to a base year. All the performance indicators of TTPI are well-structured based on the unique TT process that is prevalent in Korea. Further, TTPI can bring different size and focus of PRIs to the same scale for comparison by double-normalizing. The paper tests the effectiveness of TT consortium for the escalation of TT performances in member PRIs by highlighting the differences of TTPI's between 2005 and 2001. As a result, the paper found that the escalation of TTPI for member PRIs was greater than that for non-member PRIs. As for the characteristics of TT consortia, their respective factors obtained by TT expert survey were computed with proportion tests of differences (Z tests) to compare two perspectives between intramural and extramural groups. One of key findings is that there is general homogeneity in stakeholder perspectives regarding motivations, facilitators, barriers, and challenges. Some notable responses are as follow; the most probable motivation to join TT consortium is to share or exchange TT competences for enhanced performance. Second, the most probable facilitator is professional capability of consortium-hired personnel. Third, the foremost probable barriers to effective TT consortium are frequent change of consortium director and passive participation of member PRIs. Lastly, both publicizing TT consortia and developing performance metrics are the most important for the improvement of TT consortia. The understanding of the characteristics of TT consortia increases the likelihood of accelerated success, because TT consortia path from formation to termination encompasses many concepts, processes, principles, and factors. Finally, an analysis of the survey data combined with expert interview and observation data led the authors to derive five conditions as being critical to viable TT consortia in Korea at early stage of technology transfer systems. These conditions include policy infrastructure, proactive participation, excellent professionals, personal motivation, and teaming mechanisms. It is expected that the Korean evidence is a starting point to develop and refine the theory of TT consortia and for additional studies in other countries.

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Anticoagulation Management after Mitral Valve Replacement with the St. Jude Medical Prosthesis (승모판치환 환자의 항응혈제 치료)

  • 김종환;김영태
    • Journal of Chest Surgery
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    • v.31 no.12
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    • pp.1172-1182
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    • 1998
  • Background: Primary goal of anticoagulation treatment in patients with mechanical heart valve is the effective prevention of thromboembolism and safe avoidance of bleeding as well. Material and Method: Two-hundred and nine patients with the St. Jude Medical prosthesis operated on between 1984 and 1995, for mitral(MVR 122), aortic(AVR 39) and double mitral and aortic valve replacement(DVR 48) respectively, were studied on the practically achieved levels of anticoagulation and the clinical outcomes. Patients were on Coumadin and followed up by monthly visit to outpatient clinic for examination and prothrombin time measurement to adjust the International Normalized Ratios(INRs) within the low-intensity target range between 1.5 and 2.5. Result: A total anticoagulation follow-up period was 1082.0 patient- years(mean 62.1 months) and INRs of 10,205 measurements were available for evaluation. The accomplished INRs among the replacement groups were not significantly different and only 65% of INRs were within the target range. And, in individual patients, only 37% of patients had INRs included within the target range in more than 70% of tests during follow-up period. The levels of INRs in patients with atrial fibrillation, which was found in 57% of patients, were definitely higher than the ones measured in patients with regular rhythm(p<0.001). Thromboembolisms were experienced by 15 patients with the incidence of 1.265%/patient- year(MVR 1.412%, AVR 0.462% and DVR 1.531%/patient-year) and major bleeding by 4 patients with the incidence of 0.337%/patient-year(MVR 0.424%, AVR none and DVR 0.383%/patient-year). Frequent as well as prolonged missing of prothrombin time tests was the main risk factor strongly associated with the thromboembolic complications(odds ratio 1.99). The proportion of INRs within target range of less than 60% in individual patient was the highly significant risk factor of both thromboembolic and overall embolic and bleeding complications(p<0.004 and p<0.002 respectively). Conclusion: In conclusion, the low-intensity therapeutic target range of INRs was adequate in patients with AVR and in sinus rhythm. However, the patients with replacement of the mitral valve were more likely to require higher target range of INRs, especially in the presence of atrial fibrillation, to achieve the practical levels of anticoagulation enough to prevent thromboembolic complications effectively. For the higher therapeutic target range of INRs between 2.0∼3.0, further accumulation of clinical evidences are required. It is highly desirable to improve the patients' compliance under continuous instructions in visiting outpatient clinic and in taking daily Coumadin without omission and to keep INRs consistently within optimal range with tight control for minimization of chances and of periods of exposure to the risk of complications. And, particularly, patients with high risk of complications and with wide fluctuation of INRs should be better managed with frequent monitoring anticoagulation levels.

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Distributional Characteristics of Microcrack in Tertiary Crystalline Tuff from Northeastern Gyeongsang Basin (경상분지 북동부의 제3기 결정질 응회암에서 발달하는 미세균열의 분포특성)

  • Park, Deok-Won;Lee, Chang-Bum
    • The Journal of the Petrological Society of Korea
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    • v.18 no.4
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    • pp.315-336
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    • 2009
  • We have studied the orientational characteristics of microcrack frequency, it's length and density in Tertiary crystalline tuff from the northeastern part of the Gyeongsang Basin. 134 sets of microcracks on horizontal surfaces of 3 rock samples from Heunghae-eup were distinguished by enlarged photomicrographs of the thin sections. The variability in patterns among microcrack length-frequency histograms for three rock samples from different altitudes were derived. The pattern of histograms changes progressively from negative exponential form to log-normal form in proportion to altitude. The distribution pattern for rock sample no.1 from lower altitude shows the broad length distribution characterized by higher mean and median, and higher standard deviation. Meanwhile, this distribution pattern corresponds with characteristics of joint length distribution in sedimentary rocks of the lower part of the Gyeongsang Supergroup. The occurrence frequency of shorter microcracks increases toward both NW and NE directions from the $N0{\sim}10^{\circ}W$, with the dominant direction of $N80{\sim}90^{\circ}W$ and $N80{\sim}90^{\circ}E$, respectively. This distribution pattern represents the relative differences in formation timing among microcrack sets and the result of the new initiation of shorter microcracks. Meanwhile, the longest microcracks within $N60{\sim}70^{\circ}W$($L_{max}$:1.18 mm) and $N0{\sim}10^{\circ}W$($L_{max}$:0.80 mm) directions are seen, but this kind of microcracks are very limited in number. Whole domain of the directional angle($\theta$)-frequency(N), length(L) and density($\rho$) chart can be divided into five sections in terms of phases of the distribution of related curves. From the distribution chart, density curve shows five distinct peaks in the WNW-ESE($N70{\sim}80^{\circ}W$), NS~NNE-SSW($N0{\sim}10^{\circ}W$, $N10{\sim}20^{\circ}E$), ENE-WSW($N50{\sim}60^{\circ}E$), and nearly EW($N80{\sim}90^{\circ}E$) directions, respectively. Especially, main directions of faults correspond with the directional angle showing high density. Consequently, these distribution patterns of density curve reflect the representative maximum principal stress orientations suggested in previous studies.

An Empirical Study on Korean Stock Market using Firm Characteristic Model (한국주식시장에서 기업특성모형 적용에 관한 실증연구)

  • Kim, Soo-Kyung;Park, Jong-Hae;Byun, Young-Tae;Kim, Tae-Hyuk
    • Management & Information Systems Review
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    • v.29 no.2
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    • pp.1-25
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    • 2010
  • This study attempted to empirically test the determinants of stock returns in Korean stock market applying multi-factor model proposed by Haugen and Baker(1996). Regression models were developed using 16 variables related to liquidity, risk, historical price, price level, and profitability as independent variables and 690 stock monthly returns as dependent variable. For the statistical analysis, the data were collected from the Kis Value database and the tests of forecasting power in this study minimized various possible bias discussed in the literature as possible. The statistical results indicated that: 1) Liquidity, one-month excess return, three-month excess return, PER, ROE, and volatility of total return affect stock returns simultaneously. 2) Liquidity, one-month excess return, three-month excess return, six-month excess return, PSR, PBR, ROE, and EPS have an antecedent influence on stock returns. Meanwhile, realized returns of decile portfolios increase in proportion to predicted returns. This results supported previous study by Haugen and Baker(1996) and indicated that firm-characteristic model can better predict stock returns than CAPM. 3) The firm-characteristic model has better predictive power than Fama-French three-factor model, which indicates that a portfolio constructed based on this model can achieve excess return. This study found that expected return factor models are accurate, which is consistent with other countries' results. There exists a surprising degree of commonality in the factors that are most important in determining the expected returns among different stocks.

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Molecular Epidemiology and Antimicrobial Resistance of Methicillin-resistant Staphylococcus aureus Isolated from Nasal Swab at Intensive Care Unit (중환자실 입원 환자의 비강 도말에서 메티실린 내성 황색포도알균의 분자역학, 항생제 내성 연구)

  • Kwak, Om Sub;Kwon, Mee Hye;Jeong, Ji Hyun;Kang, Mi-il;Cheun, Ji Young;Lee, Go Eun;Kim, Young Keun;Choi, Eu Gene;Na, Moon Jun;Kwon, Hee Uk;Son, Ji Woong
    • Tuberculosis and Respiratory Diseases
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    • v.65 no.2
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    • pp.91-98
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    • 2008
  • Background: Methicillin-resistant Staphylococcus aureus (MRSA) is the most common organism associated with nosocomial infections. MRSA infections are becoming increasing important because they have emerged no only as healthcare-associated (HA) infections but also as community-associated (CA) ones. This study examined the moleculo-epidemiology of MRSA, which was isolated from nasal swabs in the intensive care unit (ICU) at Konyang University Hospital. MRSA are classified into HA-MRSA and CA-MRSA. Methods: From June to September 2006, 353 patients who were admitted to the ICU in Konyang University Hospital were enrolled in this study. Single nasal swabs were obtained for culture in the ICU on the 1st day. Pulsed-field gel electrophoresis and the antimicrobial resistant patterns were analyzed between HA- and CA-MRSA. An antimicrobial sensitivity test was also performed. Results: Forty two strains of MRSA were isolated from 353 patients (11.9%). Among the 42 isolates, HA-MRSA and CA-MRSA were found in 33 (78.6%), and 9 (21.4%), respectively. Eleven different PFGE types (type A to K) were identified. Types A (n=9) and B (n=7) were the most common for HA-MRSA, and types A (n=2) and B (n=2) were identified in CA-MRSA. The proportion of types A and B in CA-MRSA (44.4%) was similar to that in HA-MRSA (48.5%). The rates of resistance rates to erythromycin and ciprofloxacin were higher in HA-MRSA than in CA-MRSA. Conclusion: The rate of isolation of MRSA in an ICU setting was 11.9%. HA-MRSA was isolated more frequently than CA-MRSA. The rate of resistance of HA-MRSA to erythromycin and ciprofloxacin was higher than that of CA-MRSA. Despite the small number of subjects, the main isolates (type A and B) of CA-MRSA were similar to those of HA-MRSA.

Analysis of Growth Characteristics and Aboveground Carbon Storage for Zelkova serrata Artificial Forests in Gwangneung Experimental Forest (광릉시험림 내 느티나무(Zelkova serrata) 인공림의 생장특성 및 지상부 탄소저장량 분석)

  • Kim, Hyun-Seop;Bae, Sang-Won;Lee, Sang-Tae;Hwang, Jae-Hong
    • Journal of Korean Society of Forest Science
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    • v.99 no.1
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    • pp.144-152
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    • 2010
  • This study was conducted to analyze the growth characteristics and aboveground carbon storage for old growth Zelkova serrata artificial forests (site1: age class IX, site2: age class VIII) in Gwangneung Experimental Forest. The trees were classified by crown classes for analyzing forest stand structure. The growth characteristics were analized through ringwidth increment by crown classes and stem analysis of dominant trees. There were a wide range of DBH (site1: 8~62 cm, site2: 14~40 cm) and height (site1: 8~26 m, site2: 12~26 m) distributions and revealed different growth characteristics by crown classes in both sites. The mean annual increment (MAI) of ringwidth for the last 5 years of dominant trees for site1 (3.3 mm) was higher than MAI of ringwidth of total growth period (2.3 mm) and MAI of ringwidth for the last 5 years of dominant trees for site2 (2.2 mm) was equal to MAI of ringwidth of total growth period (2.2 mm). Also, the growth increment of ringwidth by crown classes had significant differences between dominant tree and the others crown classes (p<0.01) in both sites. As a results of stem analysis of dominant trees in both sites, there were similar to their volume between site1 (1.106 $m^3$) and site2 (1.035 $m^3$). In spite of old age, the annual increment of volume has been increasing steadily until recent year. Meanwhile, total aboveground carbon storage of site1 (65.6 Mg C $ha^{-1}$) was higher than that of site2 (56.1 Mg C $ha^{-1}$). The proportion of dominant and co-dominant trees to total aboveground carbon storage was more than 90% and the greatest individual aboveground carbon storage by crown classes was dominant tree in all both sites. However, individual aboveground carbon storage of dominant tree in site1 had 0.054 Mg C $tree^{-1}$ more than site2 owing to the differences from average DBH of dominant trees by sites. We think that these results will contribute to the forest practice for Zelkova serrata artificial forests as a basic information.

Cross Resistance of Fluoroquinolone Drugs on gyrA Gene Mutation in Mycobacterium tuberculosis (결핵균에서 gyrA 유전자 돌연변이에 따른 Fluoroquinolone계 약제들의 교차내성)

  • Park, Young Kil;Park, Chan Hong;Koh, Won-Jung;Kwon, O Jung;Kim, Bum Jun;Kook, Yoon Hoh;Cho, Sang Nae;Chang, Chulhun;Bai, Gill Han
    • Tuberculosis and Respiratory Diseases
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    • v.59 no.3
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    • pp.250-256
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    • 2005
  • Background : Fluoroquinolone drugs are an important anti-tuberculous agent for the treatment of multi-drug resistant tuberculosis. However, many drugs belonging to the fluoroquinolones have different cross resistance to each other. Methods : Sixty-three ofloxacin (OFX) resistant and 10 pan-susceptible M. tuberculosis isolates were selected, and compared for their cross resistance using a proportion method on Lowenstein-Jensen media, containing ofloxacin (OFX), ciprofloxacin (CIP), levofloxacin (LVX), moxifloxacin (MXF), gatifloxacin (GAT) and sparfloxacin (SPX), at concentrations ranging from 0.5 to $3{\mu}g/ml$. DNA extracted from the isolates was directly sequenced after amplifying from the gyrA and gyrB genes. Results : The 63 OFX resistant M. tuberculosis isolates showed complete cross resistance to CIP, but only 90.5, 44.4, 36.5 and 46.0% to LVX, MXF, GAT, and to SPX, respectively. Fifty-one of the isolates (81.0%) had point mutations in codons 88, 90, 91 and 94 in gyrA, which are known to be correlated with OFX resistance. The Gly88Ala, Ala90Valand Asp94Ala mutations in gyrA showed a tendency to be susceptible to MXF, GAT and SPX. Only 4 isolates had mutations in the gyrB gene, which did not affect the OFX resistance. Conclusion : About 60% of the OFX resistant M. tuberculosis isolates were susceptible to GAT, SPX and MXF. These fluoroquinolones may be useful in the treatment of TB patients showing OFX resistance.