• Title/Summary/Keyword: difference sequence space

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STATISTICAL SURVEY FOR THE PHYSICAL CHARACTERISTIC OF NEAR CONTACT BINARY(NCBs) (근접촉쌍성(NCBs)의 물리적 특성에 대한 통계적 분석)

  • Oh, Kyu-Dong
    • Journal of Astronomy and Space Sciences
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    • v.22 no.3
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    • pp.233-242
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    • 2005
  • The absolute dimensions and orbital elements of 66 near contact binaries, collected from literatures, have been analyzed to investigate the physical characteristics of the near contact binaries as well as co-relations among physical parameters. The relationship between the mass ratio and luminosity ratio of the near contact binary systems have been obtained as a $L_2/L_1{\approx}(M_2/M_1)^{1.45}$, which is similar to that of the early type contact binary system. The physical parameters of the new contact binaries show that the difference in mass, radius, luminosity and temperature between the primary and the secondary components for the F type NCBs are smaller than those for the A type NCBs. In H-R diagram, the components of the A types are located closer to the terminal age main sequence than those of the F types.

Prediction of Spring-in of Curved Laminated Composite Structure (굴곡 형상 복합재 구조물의 스프링-인 예측)

  • Oh, Jae-Min;Kim, Wie-Dae
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.43 no.1
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    • pp.1-7
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    • 2015
  • This paper predicts the spring-in effect of curved laminated composite structure for various stacking sequence using finite element analysis(ABAQUS). In composite manufacturing process, large temperature difference, different coefficient of thermal expansion and chemical shrinkage effect cause distortion of composite parts such as spring-in and warpage. Distortion of composite structure is important issue on quality of product, and it should be considered in manufacturing process. In finite element analysis, a CHILE(Cure Hardening Instantaneously Linear Elastic) model and chemical shrinkage effects are considered developing user subroutine in ABAQUS and some cases are simulated.

A Numerical Study of a Hemodynamical Model for Tumor Angiogenesis (종양혈관생성의 혈류역학 모델에 대한 수치해석 연구)

  • Ko H. J.;Shim E. B.;Cho K. H.;Jung G. S.
    • Proceedings of the KSME Conference
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    • 2002.08a
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    • pp.711-712
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    • 2002
  • A numerical study of a hemodynamical model for the tumor angiogenesis is carried out. The tumor angiogenesis process is comprised of a sequence of events; secretion of tumor angiogenesis factor(TAF) from the solid tumor, degradation of the basement membrane of nearby blood vessels, migration and proliferation of the endothelial cells. The model takes into account the effect of TAF concentration and endothelial cell density, and their conservation equations are represented as a set of one-dimensional initial boundary value problems. These equations are discretized by using a finite difference method in which the second order schemes both in time and in space are used. The effects of the parameters contained in the model are Investigated extensively through the numerical simulation of the discretized model. The result for the typical case compares very well with the known result.

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Development of an X-window Program, XFAP, for Assembling Contigs from DNA Fragment Data (DNA 염기 서열로부터 contig 구성을 위한 프로그램 XFAP의 개발)

  • Lee, Byung-Uk;Park, Kie-Jung;Kim, Seung-Moak
    • Korean Journal of Microbiology
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    • v.34 no.1_2
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    • pp.58-63
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    • 1998
  • Fragment assembly problem is to reconstruct DNA sequence contigs from a collection of fragment sequences. We have developed an efficient X-window program, XFAP, for assembling DNA fragments. In the XFAP, the dimer frequency comparison method is used to quickly eliminate pairs of fragments that can not overlap. This method takes advantage of the difference of dimer frequencies within the minimum acceptable overlap length in each fragment pair. Hirschberg algorithm is applied to compute the maximal-scoring overlapping alignment in linear space. The perfomance of XFAP was tested on a set of DNA fragment sequences extracted from long DNA sequences of GenBank by a fragmentation program and showed a great improvement in execution time, especially as the number of fragments increases.

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Ribosomal Crystallography: Peptide Bond Formation, Chaperone Assistance and Antibiotics Activity

  • Yonath, Ada
    • Molecules and Cells
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    • v.20 no.1
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    • pp.1-16
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    • 2005
  • The peptidyl transferase center (PTC) is located in a protein free environment, thus confirming that the ribosome is a ribozyme. This arched void has dimensions suitable for accommodating the 3'ends of the A-and the P-site tRNAs, and is situated within a universal sizable symmetry-related region that connects all ribosomal functional centers involved in amino-acid polymerization. The linkage between the elaborate PTC architecture and the A-site tRNA position revealed that the A-to P-site passage of the tRNA 3'end is performed by a rotatory motion, which leads to stereochemistry suitable for peptide bond formation and for substrate mediated catalysis, thus suggesting that the PTC evolved by genefusion. Adjacent to the PTC is the entrance of the protein exit tunnel, shown to play active roles in sequence-specific gating of nascent chains and in responding to cellular signals. This tunnel also provides a site that may be exploited for local co-translational folding and seems to assist in nascent chain trafficking into the hydrophobic space formed by the first bacterial chaperone, the trigger factor. Many antibiotics target ribosomes. Although the ribosome is highly conserved, subtle sequence and/or conformational variations enable drug selectivity, thus facilitating clinical usage. Comparisons of high-resolution structures of complexes of antibiotics bound to ribosomes from eubacteria resembling pathogens, to an archaeon that shares properties with eukaryotes and to its mutant that allows antibiotics binding, demonstrated the unambiguous difference between mere binding and therapeutical effectiveness. The observed variability in antibiotics inhibitory modes, accompanied by the elucidation of the structural basis to antibiotics mechanism justifies expectations for structural based improved properties of existing compounds as well as for the development of novel drugs.

An Analysis of the Characteristics on the Middle School Students' Thinking Processes in Solving Physics Problems (물리문제(物理問題) 해결과정(解決過程)에서 중학생(中學生)들의 사고과정(思考過程)의 특성(特性) 분석(分析))

  • Park, Hac-Kyoo;Lee, Yong-Hyun
    • Journal of The Korean Association For Science Education
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    • v.13 no.1
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    • pp.31-47
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    • 1993
  • This study was intended to find the characteristics of the middle school students' thinking processes and problem spaces when they solved the physics problems. Ten ninth grade students in Chon-Buk Do, Korea were participated in this study. The researcher investigated their thinking processes in solving 5 physics problems on electric circuit. "Thinking aloud" method was used as a research method. The students' thinking processes were recorded using an audio tape recorder and transfered into protocols. The protocols were analyzed by problem solving process coding system which was developed by Lee(1987) on the basis of Larkin's problem solving process model. The results are as follows : (1) On the average 2.85 items were solved among 5 test items, and only one person could solve all of the items correctly. (2) Problems were solved in sequence of understanding the problem, planning, carrying out the plan, and evaluating steps regardless of the problem difficulty. (3) In regard to the thinking process steps, there was no difference between the good solvers and the poor ones. But in the detail performance of problem solving, the former was different from the latter in respect with using the design of general solving procedure. (4) The basic problem spaces by the item analysis were divided into two classes. One was the problem space by using Qualitative approach in problem solving, and the other was one by using Quantitative approach. As novices in physics problem solving, most of the students used the problem space by using the Quantitative approach.

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AN ELECTROMYOGRAGHIC STUDY OF MUSCULAR ACTIVITIES OF TONGUE AND LIP MUSCLES IN ANTERIOR OPEN-BITE (개방교합자의 설근과 구륜근 활성도에 관한 연구)

  • Choi, Yeon-Suk;Lee, Ki-Soo;Park, Young-Guk
    • The korean journal of orthodontics
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    • v.24 no.2
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    • pp.233-246
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    • 1994
  • The purpose of the present study was to investigate the difference of muscular activities of the tongue and lip muscles between anterior open-bite and normal occlusion during various function. Thirty eight subjects of 12.1-39.6 years were employed in this study : Eighteen subjects were anterior open-bites and tweenty subjects were normal occlusions. During rest position, maximum effort of lip sealing, command swallow of saliva and sucking & swallowing of juice, the electromyographic datas of the genioglossus, superior longitudinal muscle of tongue, upper and lower orbicularis oris were recorded and integrated with Medelec MS 25 electromyographic machine. Lateral cephalometric radiographs were taken on all subjects for the analysis of tongue posture and size. All data were recored and statistically processed. The findings of this study can be summerized as follows : 1. During the rest position, muscular activity of tongue was higher than that of lip muscle in open-bite, but no difference in normal occlusion group. 2. During the swallowing of juice, the activity of orbicularis oris was higher than that of genioglossus in open-bite. But the normal occusion was showed higher activity of tongue during the swallowing of juice. 3. The open-bite, compared to the normal occlusion, had higher value of tongue muscle activity during the rest position. 4. Compared to normal occlusion group, the open-bite had higher value of lip muscle activity during the sucking and swallowing of juice. 5. During the command swallow of saliva, the normal occlusion was showed harmonious swallowing pattern, but the open-bite showed much variation and disharmony in muscular contraction sequence, tended to absent of lip muscle activity. 6. At the lateral cephalometric radiographs, compared to the normal occlusion, the open-bite was showed lower tongue posture. But no difference was found in intermaxillary space. It is suggested that the open-bite, compared to the normal occlusion, had higher muscular activity of tongue during the rest position and various functions, showed lower tongue posture on the lateral cephalogram. In the development of anterior open-bite malocclusion, these factors may be an etiologic factor.

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Algorithm for Judging Anomalies Using Sliding Window to Reproduce the Color Temperature Cycle of Natural Light (자연광의 색온도 주기 재현을 위한 슬라이딩 윈도우 기반 이상치 판정 알고리즘)

  • Jeon, Geon Woo;Oh, Seung Taek;Lim, Jae Hyun
    • Journal of Korea Multimedia Society
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    • v.24 no.1
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    • pp.30-39
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    • 2021
  • Research in the field of health lighting has continued to advance to reproduce the color temperature of natural light which periodically changes. However, most of this research could only reproduce a uniform circadian color temperature of natural light, therefore failing to realize the characteristics of the circadian cycle of color temperature difference by latitude and longitude. To reproduce the color temperature of natural light on which the characteristics of a region are reflected, the collection technology of real-time characteristics of natural light is needed. If the color temperatures which are not within a periodical pattern due to climate changes, etc., are measured, it will be difficult to judge the occurrence (presence) of the anomalies and to reproduce the circadian cycle of the color temperature of natural light. Therefore, this study proposes an algorithm for judging the anomalies in real time based on the sliding window to reproduce the color temperature of natural light. First, the natural light characteristics DB collected through the on-site measurement were analyzed, the differential values at a one-minute interval were calculated and examined, and then representative color temperature circadian patterns by solar terms were drawn. The anomalies were then detected by the application of the sliding window that calculated the deviation of the color temperature for the measured color temperature data set, which was collected through RGB sensors, while moving along the time sequence. In addition, the presence of anomalies was verified through the comparison study between the detection results and the representative circadian cycle of the color temperature by solar term. The judgment method for the anomalies from the measured color temperature of natural light was proposed for the first time, confirming that the proposed method was capable of detecting the anomalies with an average accuracy of 94.6%.

Keyhole Imaging Combined Phase Contrast MR Angiography Technique (Keyhole Imaging기법을 적용한 위상대조도 자기공명 혈관조영기법)

  • Lee, D.H.;Hong, C.P.;Han, B.S.;Lee, M.W.
    • Journal of Biomedical Engineering Research
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    • v.33 no.2
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    • pp.72-77
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    • 2012
  • Phase Contrast MR Angiography(PC MRA) is excellent MRA technique for measuring the velocity of vessels in the human body. PC MRA need to at least four images for angiogram reconstruction and it caused longer scan time. Therefore, we used keyhole imaging combined PC MRA to reduce the scan time. However, keyhole imaging can lead the erroneous effects as loss of phase information or frequency discontinuous. In this study, we applied the keyhole imaging combined 2D PC MRA for improving the temporal resolution and also measured the velocity to evaluate the accuracy of phase information. We used 0.32T MRI scanner(Magfinder II, Scimedix, Korea). Using the 2D PC MRA pulse sequence, the vascular images for a human brain targeted on the Superior Sagittal Sinus(SSS) were obtained. We applied tukey window function for keyhole images to minimize the ringing artifact and erroneous factors that are induced frequency discontinuous and phase information loss. We also applied zero-padded algorithm to peripheral missing k-space lines to compare keyhole imaging results and the artifact power(AP) value was measured on the complex difference images to validate the image quality. Consider as based on our results, heavy image distortions and artifacts were shown until using at least 50% keyhole factor. Using above the 50% keyhole factors are shown well reconstructed and matched for magnitude images and velocity information measurements. In conclusion, we confirmed the image quality and velocity information of keyhole technique combined 2D PC MRA. Especially, measured velocity information through the keyhole imaging combination was similar to the velocity information of full sampled k-space image despite of frequency discontinuous and phase information loss in the keyhole imaging reconstruction process. Consequently, the keyhole imaging combined 2D PC MRA will give some clinical usefulness and advantages as improving the temporal resolution and measuring the velocity information via selecting the appropriate keyhole factor at low tesla MRI system.

Molecular cloning and characterization of β-1,3-glucanase gene from Zoysia japonica steud (들잔디로부터 β-1,3-glucanase 유전자의 클로닝 및 특성분석)

  • Kang, So-Mi;Kang, Hong-Gyu;Sun, Hyeon-Jin;Yang, Dae-Hwa;Kwon, Yong-Ik;Ko, Suk-Min;Lee, Hyo-Yeon
    • Journal of Plant Biotechnology
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    • v.43 no.4
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    • pp.450-456
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    • 2016
  • Rhizoctonia leaf blight (large patch) has become a serious problem in Korean lawn grass, which is extremely hard to treat and develops mostly from the roots of lawn grass to wither it away. Rhizoctonia leaf blight (large patch) is caused by Rhizoctonia solani AG2-2 (IV). To develop zoysia japonica with strong disease tolerance against this pathogenic bacterium, ${\beta}-1,3-glucanase$ was cloned from zoysia japonica, which is one of the PR-Proteins known to play a critical role in plant defense reaction. ${\beta}-1,3-glucanase$ is known to be generated within the cells when plant tissues have a hypersensitive reaction due to virus or bacterium infection and secreted outside the cells to play mainly the function of resistance against pathogenic bacteria in the space between the cells. This study utilized the commonly preserved part in the sequence of corn, wheat, barley, and rice which had been researched for their disease tolerance among the ${\beta}-1,3-glucanase$ monocotyledonous plants. Based on the part, degenerate PCR was performed to find out the sequence and full-length cDNA was cloned. E.coli over-expression was conducted in this study to mass purify target protein and implement in vitro activation measurement and antibacterial test. In addition, to interpret the functions of ZjGlu1 gene, each gene-incorporating plant transformation vectors were produced to make lawn grass transformant. Based on ZjGlu1 protein, antibacterial activity test was conducted on 9 strains. As a result, R. cerealis, F. culmorum, R.solani AG-1 (1B), and T. atroviride were found to have antibacterial activity. The gene-specific expression amount in each organ showed no huge difference in the organs based upon the transformant and against 18s gene expression amount.