• Title/Summary/Keyword: diagnostic tool

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유전자 알고리듬을 이용한 다중이상치 탐색

  • Go Yeong-Hyeon;Lee Hye-Seon;Jeon Chi-Hyeok
    • Proceedings of the Korean Statistical Society Conference
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    • 2000.11a
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    • pp.173-179
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    • 2000
  • Genetic algorithm(GA) is applied for detecting multiple outliers. GA is a heuristic optimization tool solving for near optimal solution. We compare the performance of GA and the other diagnostic measures commonly used for detecting outliers in regression model. The results show that GA seems to have better performance than the others for the detection of multiple outliers.

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A Noise Control of the Incineration Plant and the Pump (소각장과 펌프의 이상소음 제어)

  • 주원호;박진화;배종국;정균양
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 1998.04a
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    • pp.741-746
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    • 1998
  • A severe noise in industrial field can be sometimes generated from unexpected installation error and misunderstanding of industrial machinery. To solve the noise problem, the diagnostic tool is generally applied to identify the noise source and to detect the fault of machinery. And then, the suitable control countermeasure corresponding to the diagnostic results is presented. In this paper, two control cases an noise problem of the Incineration Plant and the Pump are introduced.

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Comparative Assessment of Diagnostic Performances of Two Commercial Rapid Diagnostic Test Kits for Detection of Plasmodium spp. in Ugandan Patients with Malaria

  • Bahk, Young Yil;Park, Seo Hye;Lee, Woojoo;Jin, Kyoung;Ahn, Seong Kyu;Na, Byoung-Kuk;Kim, Tong-Soo
    • Parasites, Hosts and Diseases
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    • v.56 no.5
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    • pp.447-452
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    • 2018
  • Prompt diagnosis of malaria cases with rapid diagnostic tests (RDTs) has been widely adopted as an effective malaria diagnostic tool in many malaria endemic countries, primarily due to their easy operation, fast result output, and straightforward interpretation. However, there has been controversy about the diagnostic accuracy of RDTs. This study was conducted to evaluate the diagnostic performances of the 2 commercially available malaria RDT kits, RapiGEN Malaria Ag Pf/Pv (pLDH/pLDH) and Asan $EasyTest^{TM}$ Malaria Ag Pf/Pv (HRP-2/pLDH) for their abilities to detect Plasmodium species in blood samples collected from Ugandan patients with malaria. To evaluate the diagnostic performances of these 2 RDT kits, 229 blood samples were tested for malaria infection by microscopic examination and a species-specific nested polymerase chain reaction. The detection sensitivities for P. falciparum of Malaria Ag Pf/Pv (pLDH/pLDH) and Asan $EasyTest^{TM}$ Malaria Ag Pf/Pv (HRP-2/pLDH) were 87.83% and 89.57%, respectively. The specificities of the 2 RDTs were 100% for P. falciparum and mixed P. falciparum/P. vivax infections. These results suggest that the 2 RDT kits showed reasonable levels of diagnostic performances for detection of the malaria parasites from Ugandan patients. However, neither kit could effectively detect P. falciparum infections with low parasitaemia (<$500parasites/{\mu}l$).

Diagnostic Usefulness and Limitation of Fine Needle Aspiration Cytology of Lymph Node - Analysis of 176 Cases Confirmed by Biopsy - (림프절 세침흡인 세포검사의 진단적 유용성과 한계 - 생검으로 확진한 176 예의 분석 -)

  • Kim, Hee-Sung;Kim, Dae-Soo;Oh, Young-Lyun;Ko, Young-Hyeh;Ree, Howe-J.
    • The Korean Journal of Cytopathology
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    • v.10 no.1
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    • pp.35-42
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    • 1999
  • The accuracy of fine needle aspiration cytology(FNAC) of the lymph node was investigated through a review of 176 FNAC cases and the corresponding biopsies. We chose 157 FNAC cases after the exclusion of 19 inadequate ones. Sensitivity of malignancy was 94.0%, specificity 100%, false negativity 6.0%, and false positivity 0.0%. The overall diagnostic accuracy was 96.8%. Sensitivity of metastatic carcinoma was 98.0% and that of malignant lymphoma was 87.9%. False negative cases included one metastatic carcinoma and four malignant lymphomas. The aspirates of metastatic carcinoma with false negativity exhibited a diffuse smear of keratin debris without viable cells, which led to the difficulty in differentiation from benign epithelial cyst. The cases of malignant lymphoma with false negative diagnosis were two Hodgkin diseases, one Lennert's lymphoma, and one peripheral T cell lymphoma in the histologic sections. On the analysis of 39 cases of tuberculosis, 17 cases(43.6%) were diagnosed as tuberculosis, 4(10.3%) as granulomatous lymphadenitis, 3(7.7%) as necrotizing lymphadenitis, and 15(38.5%) as reactive hyperplasia or pyogenic inflammation. Sensitivity of tuberculosis was 53.9%. In conclusion, lymph node FNAC is an excellent non-invasive diagnostic tool for the diagnosis of metastatic carcinoma. The diagnostic accuracy of malignant lymphoma could be improved with flow cytometry or polymerase chain reaction for antigen receptor genes. For the FNAC diagnosis of tuberculosis, AFB stain, culture, and PCR would be helpful as adjuvant techniques.

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Usefulness of MR Imaging for Diseases of the Small Intestine: Comparison with CT

  • Ji-Hoon Kim;Hyun Kwon Ha;Min Jee Sohn;Byung Suck Shin;Young Suk Lee;Soo Yoon Chung;Pyo Nyun Kim;Moon-Gyu Lee;Yong-Ho Auh
    • Korean Journal of Radiology
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    • v.1 no.1
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    • pp.43-50
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    • 2000
  • Objective: To evaluate the usefulness of MR imaging for diseases of the small intestine, emphasizing a comparison with CT. Materials and Methods: Thirty-four patients who underwent both CT and MR imaging using FLASH 2D and HASTE sequences were analyzed. All patients had various small bowel diseases with variable association of peritoneal lesions. We compared the detectabilities of CT and MR imaging using different MR pulse sequences. The capability for analyzing the characteristics of small intestinal disease was also compared. Results: MR imaging was nearly equal to CT for detecting intraluminal or peritoneal masses, lesions in the bowel and mesentery, and small bowel obstruction, but was definitely inferior for detecting omental lesions. The most successful MR imaging sequence was HASTE for demonstrating bowel wall thickening, coronal FLASH 2D for mesenteric lesions, and axial FLASH 2D for omental lesions. MR imaging yielded greater information than CT in six of 12 inflammatory bowel diseases, while it was equal to CT in six of seven neoplasms and inferior in five of seven mesenteric ischemia. In determining the primary causes of 15 intestinal obstructions, MR imaging was correct in 11 (73%) and CT in nine (60%) patients. Conclusion: MR imaging can serve as an alternative diagnostic tool for patients with suspected inflammatory bowel disease, small intestinal neoplasm or obstruction.

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Study on the Application of Oriental Medical Evaluation to Dementia (치매 한의진단 평가도구 적용 연구)

  • Kim, Ka-Na;Bae, Hyunsu;Hwang, Wei-Wan;Cho, Seung-Hun
    • Journal of Oriental Neuropsychiatry
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    • v.25 no.4
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    • pp.383-388
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    • 2014
  • Objectives: Patients with dementia are increasing in Korea. So the importance of accurate diagnosis and treatment of dementia is growing. In this paper, we evaluated the result of employing the Korean medical diagnostic pattern as a tool in clinics. Methods: Patients diagnosed with Alzheimer's disease were evaluated using the Korean medical diagnostic pattern tool. Results: The number of patients with liver-kidney yin deficiency pattern/syndrome was 35. Analyzing the ratio difference between the 'liver-kidney yin deficiency' group and the 'not liver-kidney yin deficiency' group revealed that the ratio of the responses to the fourth question was less than zero. The ratio of the responses to the fifth, seventh, and eight questions were all less than 10%. The ratio of the responses to the first and second questions were greater than 30%. Conclusions: Of the six diagnostic patterns, liver-kidney yin deficiency was the greatest in the study subjects. The fourth question in the liver-kidney yin deficiency tool tests for the lack of appropriateness whereas the fifth, seventh, and eight questions test for lack of discrimination. Applying more weight to the first and second questions was an excellent choice to increase the discrimination.

Analyzing Assessment Factors to Develop a Privacy Impact Assessment Pre-Diagnostic Tool (개인정보 영향평가 사전진단도구 개발을 위한 평가 요소 분석)

  • Young-Ae Jung
    • Journal of Platform Technology
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    • v.12 no.1
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    • pp.151-163
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    • 2024
  • The Privacy Impact Assessment, PIPA in Korea refers to the process of analyzing risk factors and identifying improvements that must be carried out by organizations that operate personal information files as stipulated in Article 33 of the Personal Information Protection Act, PIPA and Article 35 of the Enforcement Decree of the PIPA. There are two main limitations of the PIA in Korea. The first limitation is that the targets of the PIA are limited to public institutions and organizations that are legally equivalent to public institutions, and the second limitation is that only organizations with adequate manpower, facilities, and other necessary requirements which are regulated upon the Enforcement Decree of the PIPA can conduct a PIA. This paper proposes to develop a preliminary diagnostic tool that can be performed by private companies, small and medium-sized venture companies, and small businesses in the era of rapidly developing data in recent years and presents an analysis of specific assessment factors. The results of this study are provided in the form of a self-checklist, which is expected to serve as a pre-diagnostic tool for the PIA that can be easily accessed by the general public. It is also expected to contribute to strengthening privacy protection and achieving legal compliance at the national level.

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A New Cancer Cell Detection Method Using an Infectivity-enhanced Adenoviral Vector

  • Uchino, Junji;Takayama, Koichi;Nakagaki, Noriaki;Shuo, Wang;Hisasue, Junko;Nakatom, Keita;Ohta, Keiichi;Hirano, Ryosuke;Tashiro, Naoki;Miiru, Izumi;Fujita, Masaki;Watanabe, Kentaro;Nakanishi, Yoichi
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5551-5556
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    • 2012
  • Cytological examination is widely used as a diagnostic tool because of the ease of collecting cells from the involved area. However, the diagnostic yield of cytological examination is unsatisfactory; the reasons include sampling error, poorly prepared samples, small numbers of malignant cells, and low grades of cellular atypia. In this study, we focused on the high infectivity of adenovirus towards epithelial cells and applied the luciferase-expressing adenoviral vector to a new cancer cell detection tool. In addition, adenoviral infectivity was enhanced by modifying viral fiber proteins. The sensitivity of the diagnostic tool was tested using the NCI-H1299 lung cancer cell line, and validated in body fluid samples from cancer patients with a variety of etiology. Results showed that the adenovirus efficiently transfected NCI-H1299 with high sensitivity. Only 10 cancer cells were sufficient for detection of luciferase signals. In body fluid samples, the adenovirus confirmed the diagnosis for malignant and benign cancer, but not in non-epithelial cell derived samples. This study provides proof-of-concept for a more reliable and sensitive diagnostic tool for epithelium-derived cancer.

Analysis of the Correlation Between Sarcopenia and Locomotive Syndrome in the Elderly in Korea (국내 노인의 근감소증과 운동기능저하증후군에 대한 분석 연구)

  • Kim, Myung-Chul;Cheon, Ji-Yeon;Kim, Hae-In;Chung, Dong-Kun;Bae, Won-Sik
    • Journal of The Korean Society of Integrative Medicine
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    • v.10 no.2
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    • pp.1-11
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    • 2022
  • Purpose : This study was conducted to assess the status of sarcopenia and locomotive syndrome in the Korean elderly population over 65 years of age by applying the recently updated screening tool for diagnostic evaluation of sarcopenia and locomotive syndrome. Methods : Sarcopenia and locomotive syndrome (LS) were diagnosed and evaluated in 210 Korean elderly people over 65 years of age. There were 36 patients in the "sarcopenia group", 164 in the "locomotive syndrome group", and 10 in the "normal group". The collected data were analyzed using the chi-square and Kruskal-Wallis tests. Results : The diagnostic evaluation of sarcopenia and LS showed the presence of sarcopenia in 9.05 % of males and 8.10% females among the Korean elderly population over 65 years of age. Prevalence of stage 1 locomotive syndrome (LS 1) was 95.24 %; stage 2, (LS 2) 36.19 %; and stage 3 (LS 3), 16.19 % among the study population. Both the sarcopenia diagnostic indicator and the LS evaluation indicators showed significant differences between the three groups. All the subjects in the sarcopenia group had LS; further, on comparison of the detailed composition ratio of each patient with LS, the prevalence of LS in the sarcopenia group was found to be: LS 1 41.67 %, LS 2 41.67 %, and LS 3 16.67 %, whereas in the LS group, it was found to be: LS 1 66.46 %, LS 2 16.46 %, and LS 3 17.07 %. The difference between the two groups was statistically significant. Conclusion : It was confirmed that sarcopenia is correlated with LS incidence. This suggests that the evaluation of motor LS can be used as a tool for the early diagnosis and prevention of sarcopenia in cases of functional decline due to aging in the elderly population.