• 대한전자공학회논문지SP
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• 제39권5호
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• pp.544-555
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• 2002

단위용적기법(Single-Voxel Technique) 및 다용적기법(Multi-Voxel Technique)으로 얻어진 수소원자핵 자기공명분광(Proton Magnetic Resonance Spectroscopy : 1H-MRS) 데이터를 고가의 특정 workstation이 아닌 일반 PC에서 처리${\cdot}$분석 할 수 있는 GUI(Graphical User Interface) 기반의 분광분석용 소프트웨어(S/W)를 개발하고 MRS 임상 데이터로 기초적인 시험을 하였다. 단위용적기법의 MRS 경우에는 시간 영역의 측정신호와 주파수 영역의 분광정보를 한 화면에 동시에 표시할 수 있게 하였고 필요에 따라 위상보정, 필터링(filtering), 퓨리에변환 등으로 후처리 한 후 생체 대사물질(metabolite) 별 MRS 피크 면적 비를 계산하여 정성분석을 하였다. 다용적기법의 MRS에서는 측정된 신호의 재배열 및 3차원 FFT로 분광영상(spectroscopic image)을 재구성하고 이를 T1-강조 또는 T2-강조 영상 위에 중첩시켜 해부학적 정보와 함께 표시할 수 있도록 하였다. 또한 생체에서 대사물질에 해당하는 분광정보의 각 피크의 분포도(metabolite image)를 만들고 해부학적 영상과 중첩시켰다. 병원에 설치되어있는 MR 장치에서 정상인과 뇌에 이상이 있는 환자를 대상으로 얻은 MR 분광 데이터를 처리·분석한 결과 사용자의 편의성이 높을 뿐만 아니라 신뢰성이 우수하여 임상적 활용도가 높을 것으로 기대된다.

• 대한치과교정학회지
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• 제46권1호
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• pp.13-19
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• 2016

Objective: The aim of this study was to compare the accuracy of Bolton analysis obtained from digital models scanned with the Ortho Insight three-dimensional (3D) laser scanner system to those obtained from cone-beam computed tomography (CBCT) images and traditional plaster models. Methods: CBCT scans and plaster models were obtained from 50 patients. Plaster models were scanned using the Ortho Insight 3D laser scanner; Bolton ratios were calculated with its software. CBCT scans were imported and analyzed using AVIZO software. Plaster models were measured with a digital caliper. Data were analyzed with descriptive statistics and the intraclass correlation coefficient (ICC). Results: Anterior and overall Bolton ratios obtained by the three different modalities exhibited excellent agreement (> 0.970). The mean differences between the scanned digital models and physical models and between the CBCT images and scanned digital models for overall Bolton ratios were $0.41{\pm}0.305%$ and $0.45{\pm}0.456%$, respectively; for anterior Bolton ratios, $0.59{\pm}0.520%$ and $1.01{\pm}0.780%$, respectively. ICC results showed that intraexaminer error reliability was generally excellent (> 0.858 for all three diagnostic modalities), with < 1.45% discrepancy in the Bolton analysis. Conclusions: Laser scanned digital models are highly accurate compared to physical models and CBCT scans for assessing the spatial relationships of dental arches for orthodontic diagnosis.

• Journal of Electrical Engineering and Technology
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• 제10권4호
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• pp.1915-1920
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• 2015

ISO 26262 is an international standard for the functional safety of electric and electronic systems in vehicles, and this standard has become a major issue in the automotive industry. In this paper, a functional safety compliant electronic control unit (ECU) for an electric power steering (EPS) system and a demonstration purposed EPS system are developed, and a software and hardware structure for a safety critical system is presented. EPS is the most recently introduced power steering technology for vehicles, and it can improve driver’s convenience and fuel efficiency. In conformity with the design process specified in ISO 26262, the Automotive Safety Integrity Level (ASIL) of an EPS system is evaluated, and hardware and software are designed based on an asymmetric dual processing unit architecture and an external watchdog. The developed EPS system effectively demonstrates the fault detection and diagnostic functions of a functional safety compliant ECU as well as the basic EPS functions.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2003년도 춘계학술대회 논문집
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• pp.1067-1070
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• 2003

In this paper, we present a remote measurement system for the wireless monitoring of ECU Sensor Signals of vehicle. In order to measure the ECU sensor signals, the interface circuit is designed to communicate ECU and designed terminal wirelessly according to the ISO, SAE regulation of communication protocol standard. A micro-controller 80C196KC is used for communicating ECU sensor signals. ECU sensor signals are transmitted to the RF-wireless terminal that was developed using the micro controller 80386EX. LCD, and RF-module. 80386EX software is programmed to monitor the ECU sensor signals using the Borland C++ compiler in which the half duplex method was used for the RS232 communication. The algorithms for measuring the ECU sensor signals are verified to monitor ECU state. At the same time, the information to fix the vehicle's problem can be shown on the developed monitoring software. The possibility for remote measurement of ECU sensor signals using 80386EX is also verified through the developed systems and algorithms.

• Asian Pacific Journal of Cancer Prevention
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• 제13권5호
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• pp.1911-1915
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• 2012

Aim: New technologies for the early detection of pancreatic cancer (PC) are urgently needed. The aim of the present study was to screen for the potential protein biomarkers in serum using proteomic fingerprint technology. Methods: Magnetic beads combined with surface-enhanced laser desorption/ionization (SELDI) TOF MS were used to profile and compare the protein spectra of serum samples from 85 patients with pancreatic cancer, 50 patients with acute-on-chronic pancreatitis and 98 healthy blood donors. Proteomic patterns associated with pancreatic cancer were identified with Biomarker Patterns Software. Results: A total of 37 differential m/z peaks were identified that were related to PC (P < 0.01). A tree model of biomarkers was constructed with the software based on the three biomarkers (7762 Da, 8560 Da, 11654 Da), this showing excellent separation between pancreatic cancer and non-cancer., with a sensitivity of 93.3% and a specificity of 95.6%. Blind test data showed a sensitivity of 88% and a specificity of 91.4%. Conclusions: The results suggested that serum biomarkers for pancreatic cancer can be detected using SELDI-TOF-MS combined with magnetic beads. Application of combined biomarkers may provide a powerful and reliable diagnostic method for pancreatic cancer with a high sensitivity and specificity.

• 대한설비공학회:학술대회논문집
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• 대한설비공학회 2008년도 하계학술발표대회 논문집
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• pp.3-9
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• 2008

Recently, the plant industries are being activated and plant control systems use various technologies. Because the optimized design for the plants is very important for the reducing of operation and maintenance costs, automatic control systems become more important. Plant control systems consist of the master controller, the plant networks, the programming environment for engineering, monitoring software and the field devices. The control systems should have reliability, availability and safety. Modular architecture of hardware and software makes flexible configuration of the control systems. Each component should have diagnostic functions. It follows industrial standards and makes open systems. Open systems increase accessibility against the data which is distributed in the plants. The controllers including processor and communication modules use the up-to-date technology. They have real time and fault tolerant function by duplicating processors or networks. It also enables to make the distributed control systems. The distributed architecture makes more scalable main control system. Automatic control systems can be operated with better performance. In this paper, we analyzed the requirements of the seawater desalination plants and made some consideration facts for developing the optimized controller. Also we described the design concept of the main controller, which consists of several modules. We should validate and complement the design for the reliability and better performance.

• 한국유체기계학회 논문집
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• 제20권2호
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• pp.32-40
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• 2017

In this study, an in-house program to analyze the performance degradation for gas turbines is developed using MATLAB and is validated using commercial software. This program consists of design and off-design calculations. The results of design calculation is used for reference values of off-design calculation. The off-design calculation is composed of measured and expected performance analyses, and turbine inlet temperature correction. In general, performance degradation is analyzed by comparing the results of measured and expected performance analysis. However, if gas turbine performance degrades, turbine inlet temperature might increase due to the general control logic to comply with the power demand. Therefore, it is required to consider the deviation of turbine inlet temperature from the normal value in the performance diagnosis to analyze the performance degradation exactly. In this study, a special effort is given to the correction of turbine inlet temperature. The accuracy of the developed program is confirmed by comparison with commercial software, and its capability of performance diagnosis using the turbine inlet temperature correction is demonstrated.

• Nuclear Engineering and Technology
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• 제49권3호
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• pp.484-494
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• 2017

In industrial plants such as nuclear power plants, system operations are performed by embedded controllers orchestrated by Supervisory Control and Data Acquisition (SCADA) software. A targeted attack (also termed a control aware attack) on the controller/SCADA software can lead a control system to operate in an unsafe mode or sometimes to complete shutdown of the plant. Such malware attacks can result in tremendous cost to the organization for recovery, cleanup, and maintenance activity. SCADA systems in operational mode generate huge log files. These files are useful in analysis of the plant behavior and diagnostics during an ongoing attack. However, they are bulky and difficult for manual inspection. Data mining techniques such as least squares approximation and computational methods can be used in the analysis of logs and to take proactive actions when required. This paper explores methodologies and algorithms so as to develop an effective monitoring scheme against control aware cyber attacks. It also explains soft computation techniques such as the computational geometric method and least squares approximation that can be effective in monitor design. This paper provides insights into diagnostic monitoring of its effectiveness by attack simulations on a four-tank model and using computation techniques to diagnose it. Cyber security of instrumentation and control systems used in nuclear power plants is of paramount importance and hence could be a possible target of such applications.

• International journal of advanced smart convergence
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• 제10권2호
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• pp.21-30
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• 2021

With the rapid development of artificial intelligence and big data, a lot of medical data is effectively used, and the diagnosis and analysis of diseases has entered the era of intelligence. With the increasing public health awareness, ordinary citizens have also put forward new demands for panic disorder health services. Specifically, people hope to predict the risk of panic disorder as soon as possible and grasp their own condition without leaving home. Against this backdrop, the smart health industry comes into being. In the Internet age, a lot of panic disorder health data has been accumulated, such as diagnostic records, medical record information and electronic files. At the same time, various health monitoring devices emerge one after another, enabling the collection and storage of personal daily health information at any time. How to use the above data to provide people with convenient panic disorder self-assessment services and reduce the incidence of panic disorder in China has become an urgent problem to be solved. In order to solve this problem, this research applies the context awareness to the automatic diagnosis of human diseases. While helping patients find diseases early and get treatment timely, it can effectively assist doctors in making correct diagnosis of diseases and reduce the probability of misdiagnosis and missed diagnosis.

• Clinical Endoscopy
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• 제57권3호
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• pp.302-308
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• 2024

With incessant advances in information technology and its implications in all domains of our lives, artificial intelligence (AI) has emerged as a requirement for improved machine performance. This brings forth the query of how this can benefit endoscopists and improve both diagnostic and therapeutic endoscopy in each part of the gastrointestinal tract. Additionally, it also raises the question of the recent benefits and clinical usefulness of this new technology in daily endoscopic practice. There are two main categories of AI systems: computer-assisted detection (CADe) for lesion detection and computer-assisted diagnosis (CADx) for optical biopsy and lesion characterization. Quality assurance is the next step in the complete monitoring of high-quality colonoscopies. In all cases, computer-aided endoscopy is used, as the overall results rely on the physician. Video capsule endoscopy is a unique example in which a computer operates a device, stores multiple images, and performs an accurate diagnosis. While there are many expectations, we need to standardize and assess various software packages. It is important for healthcare providers to support this new development and make its use an obligation in daily clinical practice. In summary, AI represents a breakthrough in digestive endoscopy. Screening for gastric and colonic cancer detection should be improved, particularly outside expert centers. Prospective and multicenter trials are mandatory before introducing new software into clinical practice.