• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5187-5194
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• 2014

Background: Numerous studies have suggested that selenium deficiency may be associated with an increased risk for several types of cancer, but few have focused on thyroid cancer. Materials and Methods: We examined the association between post-diagnostic fingernail selenium levels and differentiated thyroid cancer risk in a French Polynesian matched case-control study. Conditional logistic regression models were used to estimate odds ratios and 95% confidence intervals. Results: The median selenium concentration among controls was $0.76{\mu}g/g$. Significantly, we found no association between fingernail selenium levels and thyroid cancer risk after conditioning on year of birth and sex and additionally adjusting for date of birth (highest versus lowest quartile: odds-ratio=1.12, 95% confidence interval: 0.66-1.90; p-trend=0.30). After additional adjustment for other covariates, this association remained non-significant (p-trend=0.60). When restricting the analysis to thyroid cancer of 10 mm or more, selenium in nails was non-significantly positively linked to thyroid cancer risk (p-trend=0.09). Although no significant interaction was evidenced between iodine in nails and selenium in nails effect (p=0.70), a non-significant (p-trend =0.10) positive association between selenium and thyroid cancer risk was seen in patients with less than 3 ppm of iodine in nails. The highest fingernail selenium concentration in French Polynesia was in the Marquises Islands ($M=0.87{\mu}g/g$) and in the Tuamotu-Gambier Archipelago ($M=0.86{\mu}g/g$). Conclusions: Our results do not support, among individuals with sufficient levels of selenium, that greater long-term exposure to selenium may reduce thyroid cancer risk. Because these findings are based on post-diagnostic measures, studies with prediagnostic selenium are needed for corroboration.

• 한국항만경제학회지
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• 제39권4호
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• pp.147-161
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• 2023

기후변화를 비롯한 사회 문제가 심각해지면서 ESG 경영에 대한 인식은 전세계적으로 점점 높아지고 있다. 물류산업은 글로벌 공급망에서 중요한 역할을 담당하는 만큼 물류기업에 대한 ESG 경영 이행이 다양한 사회 구성원에게 요구되고 있다. 한국은 모든 기업을 대상으로 ESG 가이드라인을 마련하였으나, 물류기업 특히 중소·중견 물류기업의 특성을 고려하지 못한 한계점이 있다. 이에 본 연구는 기존 ESG 가이드라인과 대형 물류기업의 지속가능경영 사례, 선행연구 등을 검토함으로써 중소·중견 물류기업을 위한 ESG 경영 진단항목 후보를 정보공시(P), 환경(E), 사회(S), 지배구조(G) 4개 영역으로 도출하였다. 중소·중견 물류기업의 영세기업 특성을 고려한 진단항목을 축소하기 위해 본 연구는 물류기업 종사자 및 학계/연구기관 전문가 총 60명을 대상으로 설문조사를 진행하였으며, 조사결과를 토대로 주성분 분석 방법을 활용하였다. 주성분 분석결과는 정보공시의 4개 항목을 하나로 정의할 수 있으며, 환경은 16개 항목에서 3개 항목으로, 사회는 22개 항목에서 7개로, 지배구조는 20개에서 5개로 정의하였다. 본 연구는 중소·중견 물류기업 특성에 맞는 ESG 경영 진단항목을 제시하는 데에 있어 의미가 있다고 판단이 되며, 향후 유관기관에서의 가이드라인 마련과 중소·중견 물류기업에서의 ESG 경영 추진시 본 연구를 참고할 것으로 기대된다.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8163-8171
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• 2016

Background: Breast cancer is the second most cause of death (1.38 million, 10.9% of all cancer) worldwide after lung cancer. In present study, we assess the knowledge, level of awareness of risk factors and screening practices especially breast self examination (BSE) among women, considering the non-feasibility of diagnostic tools such as mammography for breast screening techniques of breast cancer in the holy city Varanasi, Uttar Pradesh, India. Materials and Methods: A cross-sectional population based survey was conducted. The investigation tool adopted was self administrated questionnaire format. Data were analysed using SPSS 20 version and Chi square test to determine significant association between various education groups with awareness and knowledge, analysis of variance was applied in order to establish significance. Results: The attitude of participants in this study, among 560 women 500 (89%) responded (age group 18-65 years), 53.8% were married. The knowledge about BSE was very low (16%) and out of them 15.6% were practised BSE only once in life time. study shown that prominent age at which women achieve their parity was 20 yrs, among 500 participants 224 women have achieved their parity from age 18 to 30 yrs. Very well known awareness about risk factors of breast cancer were alcohol (64.6%), smoking (64%) and least known awareness risk factors were early menarche (17.2%) and use of red meat (23%). The recovery factors of breast cancer cases were doctors support (95%) and family support (94.5%) as most familiar responses of the holy city Varanasi. Conclusions: The study revealed that the awareness about risk factors and practised of BSE among women in Varanasi is extremely low in comparison with other cities and countries as well (Delhi, Mumbai, Himachal Pradesh, Turkey and Nigeria). However, doctors and health workers may promote the early diagnosis of breast cancer.

• 임상간호연구
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• 제26권2호
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• pp.217-231
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• 2020

Purpose: To identify the clinical role of Advanced Practice Nurses (APN), and evaluate how other medical personnel perceive their work(difficulty, importance). Methods: A questionnaire survey was performed with 277 health care providers (APN 52, nurses 88, and medical doctors 137 [professors 51, fellows 44, & residents 42]) in a single, tertiary hospital. The questionnaire was categorized into 6 domains (total 40 tasks): 6 tasks on identifying health issues (A); 3 tasks on prescribing and conducting diagnostic tests (D); 18 tasks on disease treatment (T); 4 tasks regarding prescribing medicine (M); 3 tasks regarding medical collaboration (C); 6 tasks regarding patient education (E). The survey measured the frequency, difficulty, and importance of APN's clinical tasks, and evaluated the willingness of authorizing clinical tasks to APN. Results: The most frequent tasks for APN were A domain, lowest were T domain. The scores for perceived job difficulty were lower than those for job importance in all groups. The proportion of willingness to legally delegate clinical practices to APN was higher in A and E domains, but lower in D and T domains. However, professors, who spent the most time with APN, showed a higher willingness to legally delegate clinical practice. The participants favored medical doctors as substitutes for tasks which were not legislated for delegated job performance. Conclusion: In this study identified clinical roles that medical doctors considered possible for legal delegation to APN were identified. The results can be used as evidence for the legalization of the practice of APN.

• The Korean Journal of Pain
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• 제29권1호
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• pp.3-11
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• 2016

A nerve block is an effective tool for diagnostic and therapeutic methods. If a diagnostic nerve block is successful for pain relief and the subsequent therapeutic nerve block is effective for only a limited duration, the next step that should be considered is a nerve ablation or modulation. The nerve ablation causes iatrogenic neural degeneration aiming only for sensory or sympathetic denervation without motor deficits. Nerve ablation produces the interruption of axonal continuity, degeneration of nerve fibers distal to the lesion (Wallerian degeneration), and the eventual death of axotomized neurons. The nerve ablation methods currently available for resection/removal of innervation are performed by either chemical or thermal ablation. Meanwhile, the nerve modulation method for interruption of innervation is performed using an electromagnetic field of pulsed radiofrequency. According to Sunderland's classification, it is first and foremost suggested that current neural ablations produce third degree peripheral nerve injury (PNI) to the myelin, axon, and endoneurium without any disruption of the fascicular arrangement, perineurium, and epineurium. The merit of Sunderland's third degree PNI is to produce a reversible injury. However, its shortcoming is the recurrence of pain and the necessity of repeated ablative procedures. The molecular mechanisms related to axonal regeneration after injury include cross-talk between axons and glial cells, neurotrophic factors, extracellular matrix molecules, and their receptors. It is essential to establish a safe, long-standing denervation method without any complications in future practices based on the mechanisms of nerve degeneration as well as following regeneration.

• 부모자녀건강학회지
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• 제3권2호
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• pp.81-93
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• 2000

The role of the neonatal nurse specialist has been well established over the past decade and now reform in 21st century. Neonatal nurse specialists responsibilities in caring for critically and long-term chronically ill infants and their families are very important. Neonatal nurse specialists have a two fold responsibility in caring for these infants. First, through acquiring advanced practice education in complex neonatal care and diagnostic skills, neonatal nurse specialists meet the physiologic needs of the infant. Second, neonatal nurse specialists provide a more holistic approach to their care through evaluating the family in treatment plans and involving the family in discharge planning for the infant. In some institutions, neonatal nurse specialists are directly involved in institutional and/or home follow-up care and case management also. It is the neonatal nurse specialists responsibility to function collaboratively with the multidisciplinary team in managing critically or chronically ill infants from admission to discharge. The role of the neonatal nurse specialist case manager can be described as one that focuses on individualized care of the infant, while providing continuity of care to both the infant and family. The neonatal nurse specialist's role will vary depending on the neonatal intensive care unit(NICU). Therefore, the multidisciplinary collaborative approach to long-term management of infants in the NICU is extremely important to provide successful transition to home or to long-term rehabilitative care facilities because care for the chronically ill infant is complex and multifaceted. I suggest the role of neonatal nurse specialist in 21st century are as follows. 1. Diagnostic/patient assessment 2. Management of patient health/illness 3. Administering/monitoring therapeutic interventions and regimens 4. Monitoring/ensuring quality of health care practices 5. Organization and work role 6. Helping role 7. Teaching/coaching role 8. Management of rapidly changing situations 9. Consulting role The advanced practice nursing model of care delivered by neonatal nurse specialist's in the NICU incorporates medical and nursing role functions and emphasizes holism, caring, and a health perspective for critically and chronically ill neonates and their families.

• 대한수의학회지
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• 제55권2호
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• pp.97-103
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• 2015

In this study, the Korean veterinary medical devices management system was evaluated relative to systems in the USA, EU, and Japan. Veterinary medical devices are regulated in Korea based on the Medical Appliance Act of 1997. This was initially supervised by the Ministry of Agriculture, Food and Rural Affairs and Korea Animal Health Products Association, and subsequently by the Animal and Plant Quarantine Agency (QIA) in 2000. These devices were classified approximately 1,400 categories as instruments, supplies, artificial insemination apparatus, and other categories. Each of these devices was assigned to four regulatory grades by the QIA in 2007. The ranking system for veterinary medical devices was implemented in 2014 with 820 products from 162 companies registered by that year. However, in vitro diagnostic devices (IVDDs) for animals were managed as medical devices and biological medicine. In vitro diagnostic reagents for treating infection diseases are not subjected to either a classification or grading system. Veterinary medical devices are currently exempt from good manufacturing practices (GMP) and device tracking requirements. Due to gradual growth of the domestic veterinary medical devices market since 2008, regulation of these devices should be improved with re-examination of IVDDs and GMP certification for the effective operating system.

• 셀메드
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• 제2권2호
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• pp.17.1-17.5
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• 2012

Ayurveda is a nearly 3000 years old traditional medical system of India. Most of the time, people turn to ayurvedic physicians in desperate conditions. Here clinical practices of Ayurveda were initially found effective in the management of migraine among few patients. Later, it was developed as an ayurvedic treatment protocol (ATP) which consists of four herbo-mineral formulations (HMF), three meals and three snacks in a day with eight hours sleep at night. ATP brought significant relief in reducing the frequency, intensity of pain and associated symptoms in the migraine patients. IHS diagnostic criteria was followed to establish the diagnosis of migraine and uniform ATP was prescribed to each patient who were primarily treated by the ayurvedic physicians at their respective clinics. Such observations were presented at appropriate international forums. In an effort to validate the above, the present study carries the details of nine migraine patients who were first diagnosed and treated for migraine by a leading headache expert at Mumbai in India and were then referred to receive ATP. A total number of nine subjects volunteered to this program. Out of those, seven subjects completed 120 days of ATP. Five subjects reported significant improvement in overall symptoms of migraine. All subjects were followed up periodically for four years. No Grade II side effects were observed in any treated case. HMF has also been proved to be safe in experimental studies. Further pharmacological and randomized controlled clinical studies are in progress at the respective departments of a premier medical institute in India.

• 한국정보과학회논문지:컴퓨팅의 실제 및 레터
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• 제6권1호
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• pp.82-92
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• 2000

본 논문에서는 CC-NUMA 시스템을 위한 진단 소프트웨어에 대한 구현 방법 및 결과를 소개하였다. CC-NUMA 구조는 두 대 이상의 SMP 시스템들에 캐쉬 일관성을 유지하기 위한 하드웨어를 장착하고, 이들을 고속 연결망으로 연결함으로써 시스템의 성능 및 확장성을 향상시켜 준다. 그러나, CC-NUMA 시스템은 운용체제 측면에서는 단일 시스템 이미지로서 보여지는 반면, 하드웨어 구조와 밀접한 진단 소프트웨어에서는 이를 별개의 시스템으로 고려해야 한다. 이와 같은 구조 때문에 기존의 상용 관리 소프트웨어로는 CC-NUMA 시스템에 대한 진단 및 관리를 하기 어렵다. 또한, TCO(Total Cost of Ownership) 절감 측면에서 최근 대두되고 있는 원격 진단 및 관리의 필요성이 증가하고 있다. 본 논문에서는 이러한 요구사항에 따라 CC-NUMA 구조에 적합한 진단 소프트웨어 모듈을 설계하였으며, 원격 진단 및 관리가 용이한 클라이언트-서버 구조의 진단 메커니즘을 제시하였다. 또한, 관리자가 어느 시스템에서도 서버에 접근할 수 있는 접근성을 향상시키기 위하여 자바 기반 사용자 인터페이스를 채택하였다.

• 정보보호학회논문지
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• 제34권4호
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• pp.801-809
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• 2024

본 논문은 정보기술 시대에서 강조되는 개인 정보의 중요성과 공공기관의 개인 정보 관리의 필요성을 다룬다. 공공기관에서 처리하는 개인 정보의 양이 지속해서 증가함에 따라, 더욱 효과적인 관리체계의 필요성이 대두되었다. 이에 따라, 정부는 기존의 개인 정보 관리 수준 진단 방식을 넘어서, 더욱 강화된 평가 중심의 체계인 '개인정보 보호 수준 평가제'를 도입하였다. 본 연구는 이러한 체계 전환의 배경, 과정, 그리고 2024년에 시행된 개인정보보호법 개정안의 주요 내용을 분석한다. 또한, 문헌조사 및 사례분석을 통해 공공기관 개인정보보호 관리 수준 진단의 현황 및 한계를 평가하고, 체계 전환 후 예상되는 개선 효과와 정책적 제언을 제공한다. 본 연구는 개인정보보호 정책의 강화가 국민 신뢰 제고 및 디지털 시대의 안정적 발전에 이바지할 것으로 전망한다.