• Title/Summary/Keyword: diagnostic evaluation

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CLINICAL STUDY OF POSITRON EMISSION TOMOGRAPHY WITH $[^{18}F]$-FLUORODEOXYGLUCOSE IN MAXILLOFACIAL TUMOR DIAGNOSIS (구강 악안면 영역의 암종 진단에 있어서 $[^{18}F]$-Fluorodeoxyglucose를 이용한 양전자방출 단층촬영의 임상적 연구)

  • Kim, Jae-Hwan;Kim, Kyung-Wook;Kim, Yong-Kack
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.26 no.5
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    • pp.462-469
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    • 2000
  • Positron Emission Tomography(PET) is a new diagnostic method that can create functional images of the distribution of positron emitting radionuclides, which when administered intravenously in the body, makes possible anatomical and functional analysis by quantity of biochemical and physiological process. After genetic and biochemical changes in initial stage, malignant tumor undergoes functional changes before undergoing anatomical changes. So, early diagnosis of malignant tumors by functional analysis with PET can be achieved, replacing traditional anatomical analysis, such as computed tomography(CT) and magnetic resonance image(MRI), etc. Similarly, PET can identify malignant tumor without confusion with scar and fibrosis in follow up check. In the Korea Cancer Center Hospital(KCCH) from October 1997 to September 1999, clinical study was performed in 79 cases that underwent 89 times PET evaluation with [18F]-Fluorodeoxyglucose for diagnosis of oral and maxillofacial tumors, and the data was analysed by Bayesian $2{\times}2$ Classification Table. The results were as follows : Evaluation for initial diagnosis with FDG-PET (P<0.005) 1. Agreement rate or accuracy rate is 88.9%. 2. Sensitivity is 95.2%, and specificity 66.7%. 3. Positive predictive rate is 90.9%, and negative predictive rate 80.0%. 4. In consideration of tumor stage, diagnostic rate in less than stage II was 90% and in greater than stage III 100%. 5. In consideration of tumor size, diagnostic rate in less than T2 was 92.3% and in greater than T3 100%. After primary treatment, evaluation for follow up check with FDG-PET (P < 0.001) 1. Agreement rate or accuracy rate is 85.4%. 2. Sensitivity is 87.5%, and specificity 82.4%. 3. Positive predictive rate is 87.5%, and negative predictive rate 82.4%. 4. In 24 recurred cases, 6 had distant metastasis, and 5 of them were diagnosed with FDG-PET, resulting in diagnostic rate of FDG-PET of 83.3%. From the above results, Positron Emission Tomography with [18F]- Fluorodeoxyglucose appears to be more sensitive and accurate for detecting the presence of oral and maxillofacial tumors, and has various clinical applications such as early diagnosis of tumor in initial and follow up check and detection of distant metastasis.

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A Case of Lingual Thyroid (설갑상선(舌甲狀腺)의 1례(例))

  • Lee, Kyung-Ja
    • The Korean Journal of Nuclear Medicine
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    • v.3 no.1
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    • pp.101-105
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    • 1969
  • A case of lingual thyroid in 10 years old girl is presented with the use of radioactive iodine ($^{113}I$) and the scintigram for the diagnostic evaluation. A brief review of literature on the incidence, etiology and-development, symptomatology, diagnosis, and treatment of the lingual thyroid was done.

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Usefulness of ultrasonography radial artery diameter with lumen evaluation (초음파를 이용한 요골동맥의 직경 및 내강 평가)

  • Park Young-Hee
    • Journal of The Korean Radiological Technologist Association
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    • v.27 no.2
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    • pp.175-180
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    • 2001
  • Ⅰ. Background and Objectives : Recently the percutaneous transradial approach for coronary angiography and angioplasty has been using. When the radial artery as a graft for coronary artery bypass surgery was used, pantency increased. Many examination and

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Comprehensive review of membranoproliferative glomerulonephritis: spotlighting the latest advances in revised classification and treatment

  • Jeong Yeon Kim
    • Childhood Kidney Diseases
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    • v.27 no.2
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    • pp.64-69
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    • 2023
  • Membranoproliferative glomerulonephritis (MPGN) is a complex group of renal diseases characterized by a specific pattern of glomerular injury that includes thickening of the capillary wall and mesangial expansion, leading to a heterogeneous group of conditions. This review article offers a comprehensive overview of MPGN, its new classification, pathophysiology, diagnostic evaluation, and management options.

Applying the ACR Preliminary Diagnostic Criteria in the Diagnosis and Assessment of Fibromyalgia

  • Kim, So-Mi;Lee, Sang-Heon;Kim, Hae-Rim
    • The Korean Journal of Pain
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    • v.25 no.3
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    • pp.173-182
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    • 2012
  • Background: Fibromyalgia (FM) is characterized by chronic widespread pain with a low pain threshold. The aim of this study was to compare two criteria for the diagnosis and assessment of FM and to analyze the correlation and agreement between the 1990 and 2010 American College of Rheumatology (ACR) preliminary diagnostic criteria for FM. Methods: We studied 98 patients who had already been diagnosed as having FM using the 1990 criteria or 2010 preliminary criteria. Tender point examination, FM impact questionnaire (FIQ) and pain visual analog scale (VAS) were obtained. According to the preliminary criteria, FM was quantified as WPI (widespread pain index) and the SS scale (symptom severity) and the two criteria were compared. Results: Among 98 patients, 78.6% of the patients were diagnosed with the 1990 ACR criteria and 93.9% of the patients were diagnosed with the ACR preliminary diagnostic criteria, and there was also significant agreement between the two criteria (P < 0.01). There was a correlation with the WPI and the tender point, with the SS and the FIQ, and with the sum of the WPI and SS and the FIQ. Conclusions: The ACR preliminary diagnostic criteria for FM were in agreement with the 1990 ACR criteria during the disease course. The preliminary criteria were the more sensitive method than the 1990 criteria. In addition, the 2010 criteria might have advantages since it is easy to assess the physical and psychological symptoms and can be quantified. Therefore, the ACR preliminary diagnostic criteria for FM could be used more conveniently for clinical diagnosis and follow up evaluation after starting management of FM.

Diagnostic Efficacy of Fine Needle Aspiration Cytology, Frozen section Biopsy and Ultrasonography for a Palpable Thyroid Mass (갑상선 촉지 종괴에서 시행한 세침흡인세포검사법, 동결절편검사법 및 초음파검사법의 진단적 유용성)

  • Lee Byoung-Kil;Jung Sung-Hoo
    • Korean Journal of Head & Neck Oncology
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    • v.18 no.2
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    • pp.168-172
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    • 2002
  • Objectives: This study was done to determine the diagnostic efficacy of fine needle aspiration cytology (FNA), frozen section biopsy (FSx) and ultrasonography in a palpable thyroid mass. Materials and Methods: During the period from July 1999 to March 2002, the medical records of 98 patients who underwent a thyroidectomy for thyroid mass, at the Department of Surgery, Chonbuk National University Hospital, were reviewed retrospectively. Ninety eight cases were classified according to whether the FNA cytological diagnosis inadequate, benign, suspicious, or malignant and the FSx diagnosis benign or malignant and the ultrasonographic examination was benign, suspicious, or malignant. The diagnostic correlations of ultrasonography, FNA cytology, frozen section, and both FNA cytology and frozen section with definite histologic diagnosis were evaluated. Results: According to the FNA cytological interpretation, 76 cases were diagnosed as benign, 6 cases suspicious, 13 cases malignant, and 3 cases inadequate. The sensitivity and specificity for FNA were 86.3% and 95.9% and for FSx 95.5% and 100% respectively. The diagnostic accuracy of FNA and FSx were 93.5% and 98.9% respectively. Based on a definite histologic diagnosis, the ultrasonographic examination had a sensitivity and a specificity of 77.2% and 78.9%. Conclusion: The results confirm that FNA cytology is a reliable and useful tool in the initial evaluation of a palpable thyroid mass compared to the ultrasonographic examination. Intraoperative FSx is a valuable diagnostic procedure to confirm the cytological diagnosis with undetermined or unsatisfactory cytological diagnosis.

Analysis of Aging Insulation Characteristics of 3.3[kV] Class Induction Motor with AC Breakdown Test (절연파괴시험법을 이용한 3.3[kV] 유도전동기의 절연물 열화특성 분석)

  • Lee, Ju;Kim, Hyun-Il;Kim, Youn-Hyun;Son, Yeoung-Gyu
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.21 no.10
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    • pp.141-149
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    • 2007
  • This paper introduce to improve the reliability of the expected service life and the insulation condition evaluation of the high voltage induction motors by assessing, comparing and analyzing the correlation between the dielectric properties of the off-line insulation diagnostic test and dielectric strength on the insulation breakdown test. The insulation diagnostic tests include insulation resistance, polarization index(P.I.), dissipation factor($tan{\delta}$), maximum partial discharges($Q_{max}$) and AC breakdown test. This study evaluated the correlation between insulation diagnostic test and AC breakdown test for stator winding of high voltage induction motor. On the basis of these test results, we expect that this study can be used for effectively assessing the results of insulation diagnostic tests for similar class induction motors in service at industrial field.

Diagnostic Values of Tongue Coating Thickness and Sterno-costal Angle in Functional Dyspepsia (기능성 소화불량 환자에서 설태후박 및 흉늑각 측정의 진단적 가치)

  • Son, Ji-Young;Kim, Jin-Sung
    • The Journal of Internal Korean Medicine
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    • v.35 no.2
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    • pp.157-174
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    • 2014
  • Objectives : The aims of this study were to evaluate the diagnostic values of tongue coating thickness and sterno-costal angle as the quantitative diagnostic indicators in functional dyspepsia. Methods : We surveyed 60 functional dyspepsia patients recruited by the clinical trial, 'Clinical Trial for Evaluation on Availability of tongue diagnosis system (CTS-1000) : a Pilot study'. The patients were classified into three groups according to Rome III criteria for functional dyspepsia, and categorized into five groups according to Instrument of pattern identification for functional dyspepsia. Nepean dyspepsia index-Korean version (NDI-K) score, tongue coating thickness (percentage of tongue coating by tongue diagnosis system (CTS-1000), and weight of tongue coating by microbalance), sterno-costal angle, duration of illness and body mass index (BMI) were investigated. Results : Among the 5 types by instrument of pattern identification for functional dyspepsia, a significant difference of percentage of tongue coating was found. Percentage of tongue coating and weight of tongue coating showed significant correlation with total NDI-K score. Sterno-costal angle showed strong positive correlation with BMI and also showed significant difference between the non-overweight (BMI<23, n=32) and overweight ($BMI{\geq}23$, n=28) groups. Conclusions : Tongue coating thickness showed its potential as a new quantitative diagnostic indicator of functional dyspepsia. Further studies on the sterno-costal angle are anticipated to evaluate its potential as a new quantitative diagnostic indicator.

Development and validation of heuristics for usability improvements on web-based diagnostic assessment management system for primary-middle schoolers (초·중학생 대상 웹기반 진단평가관리시스템 사용성 개선을 위한 휴리스틱스 개발 및 검증)

  • Cha, Hyunjin;Hwang, YunJa
    • Journal of The Korean Association of Information Education
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    • v.21 no.6
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    • pp.675-690
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    • 2017
  • Preparing the 4th industrial revolution age, a diagnostic assessment management system which can collect nationwide data has been implemented and utilized for the development of the evidence-based educational policy. This study aims to develop heuristics to help to improve usability of such systems, which are utilized by primary and middle school community including teachers and students in the nationwide. To achieve the objective, previous studies related to the development of heuristics in the educational contexts as well as basic heuristics from Nielsen were reviewed, and usability problems of the web-based diagnostic-supplement system being currently utilized, as a sample system, were analyzed. Then, the first version of heuristics was developed. The developed heuristics were validated and revised through 2 rounds of the delphi methods with 15 experts. This study has an implication with preparing foundations on improving usability of such diagnostic assessment management system utilized by school community at the nationwide in educational contexts.