• Title/Summary/Keyword: devlopment

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Advantage and Disadvantage of Autoradiography - Current topics of Autoradiography in New Drug Devlopment Studies of Japan

  • Shigematsu, Akiyo;Motoji, Naomi;Mori, Keiji;Aihara, Michiaki
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1996.04a
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    • pp.229-230
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    • 1996
  • The 116 annual meeting of the Pharmaceutical Society of Japan was held in Kanazawa from March 27 to 29 in 1996, Our presentation will be concerned to a few topics in this meeting. Recently not only pharmaco- and toxico-kinetic studies but also pharmaco- and toxico-dynamic studies are beginning to be worthy of notice. This is quite reasonable, because the blood concentration-time curves of a parent compound must be useful, but it is no more than a cross section for pharmaco- and toxico-dynamic in many organs and tissues as main reaction site for drug metabolism,

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Design & Implementation of Metrics Evaluation Tool for Java Code (자바 코드 메트릭 측정 도구의 설계 및 구현)

  • Oh, Hyun-Chul;Kim, Tae-Gyun;Yoon, Seok-Jin
    • Proceedings of the Korea Information Processing Society Conference
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    • 2002.11c
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    • pp.1991-1994
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    • 2002
  • 본 논문은 기존에 작성된 자바 프로그램이나 현재 구현 중인 자바 프로그램을 대상으로 메트릭 정보를 측정하는 자동화 도구의 설계 및 구현 결과를 논한다. 이러한 도구의 구현을 위해 필요한 가장 핵심적인 기능은 자바코드에 대한 분석 기능이다. 본 논문의 내용은 한국전자통신연구원의 컴포넌트 공학 연구팀 주관으로 EJB(Enterprise Java Beans) 기술을 기반으로 컴포넌트를 개발하기 위한 환경인 COBALT(Component Based Application devlopment Tool) 시스템의 부 시스템으로 구현된 자바코드 메트릭 측정 도구의 설계 및 구현 결과를 다룬다. 본 논문에서 구현된 자바 코드 메트릭 측정 도구을 통하여 클래스의 적절한 분할, 클래스 멤버 자원의 적절한 배치, 상속 트리의 적절한 조직 등을 이룰 수 있다.

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Devlopment HLA DEVS-Obj-C Environment for Distributed Simulation (분산 시뮬레이션을 위한 HLA DEVS-Obj-C 환경 구축)

  • 최두진;조대호
    • Proceedings of the Korea Society for Simulation Conference
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    • 2002.11a
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    • pp.85-89
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    • 2002
  • Development of distributed simulation environment must be required in order to simulate the distributed models regionally and inter-operate with running simulations individually, Simulation based on DEVS formalism is difficult to simulate the distributed models. DEVS formalism is modeling methodology. To specify model, this formalism separates behavior and structure, therefore it is able to design complex model easily. HLA is standard framework of distribute simulation environment, It is defined to facilitate the interoperability and the reusability. RTI (Run Time Infrastructure) is software that provides common service to simulation systems and implementation of the HLA Interface Specification. Method of implementation is that modules cooperating with RTI are added to simulator on DEVS simulation environment. On the DEVS simulation environment (DEVS-Obj -C) that already developed, Highest class of abstract simulator uses service that RTI provide, then This environment is able to change DEVS model into Federate and run distribute simulation that inter-operates with the RTI. Because this distributed simulation environment includes convenience of modeling that obtains through the DEVS formalism and accompanies HLA standard, this environment make it possible to simulate with_ complex systems and heterogeneous simulations

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Protein-arginine methylation in myelin basic protein from mammalian brain (포유류 뇌의 미엘린 염기성 단백질에서 단백질-아르기닌 메칠화)

  • 박종옥;박형숙;김경순
    • Journal of Life Science
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    • v.8 no.1
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    • pp.109-117
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    • 1998
  • The synthesis and methylation in vivo of myleline basic protein(MBP) during the mouse brain devlopment was found to be the highest in youngest brain and declined progressively in mature brains. The relative rate of protein synthesis and methylation was a maximal ration in the youngest brain, This high ratio was wdll correlated with the higher protein methylase I (PM I) activity in younger brains. The jimpy mouse is the most severely affected dysmyelinating mutant and is characterized by failure to incorporate MBP into myelin. sheath. The MBP-specific PM I activity in 15-, 18-, and 21-days old hemizygous jimpy mice(jp/y)brains decreased by 20, 50 and 75%, respectively. Myelin fraction with different degrees of compaction were isolated from bovine brain, the most compact myelin fraction exhibited higher methylaccepting activity than the less compact dense fractions.

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Development of Dynamic Models of EUROSTAG for Stability Study PART I - Devlopment of Dynamic Models (EUROSTAG을 이용한 안정도 해석용 제어계 모델 개발 PART I - 제어계 모델 개발)

  • Kim, H.M.;Oh, T.K.;Chun, Y.H.;Kook, K.S.;Kim, S.I.
    • Proceedings of the KIEE Conference
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    • 2001.07a
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    • pp.65-67
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    • 2001
  • Because of the difficulty of acquiring new generation sites and right- of-way, additional units have been added to the existing generation sites and the transmission system has been developed into highly meshed configuration. The reliable operation of power systems has been restricted by this system characteristics. The enhancement of system analysis techniques and establishment of appropriate measures have been required in this situation. In addition the deregulation of electric power industry in Korea would give rise to better tools for power system analysis and control. In this paper, dynamic models were developed.

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Devlopment of Unmanned Rental Service supporting Infectious Disease Prevention (방역을 지원하는 무인렌탈 서비스 개발)

  • Choi, Hyo Hyun;Baek, Jae-Won;Lim, Jin-Su;Yang, DaeChul
    • Proceedings of the Korean Society of Computer Information Conference
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    • 2021.01a
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    • pp.209-210
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    • 2021
  • 현재 코로나 시대에 살아가면서 실습이 필요한 대학수업은 제대로 진행하기 힘든 상황이다. 이에 대응하기 위하여 렌탈 서비스를 통해 쉽게 물품을 빌리고, 관리하기 쉬운 시스템을 개발하였다. 직접 수령할 때에는 라즈베리파이를 이용한 열화상카메라로 온도 체크를 하고 특정 온도가 넘었을 시 LED 전등이 빨간색으로 깜빡거리게 되며 대여신청하면 정보가 담긴 대여 번호가 생성 되고 스마트박스에 대여 번호 확인 후 도어락이 풀리게 되는 무인 렌탈 서비스를 개발하였다.

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Mechanical Properties and Fabrication of WC-Co Hard Materials by Rapid Sintering Method for Friction Stir Welding Tool Application (급속소결 방법을 이용한 마찰교반 접합 툴용 WC-Co 소결체 제조 및 특성 평가)

  • Park, Hyun-Kuk;Youn, Hee-Jun;Ryu, Jung-Han;Jang, Jun-Ho;Shon, In-Jin;Oh, Ik-Hyun
    • Journal of Welding and Joining
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    • v.30 no.6
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    • pp.92-97
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    • 2012
  • Using the pulsed current activated sintering method, the WC-10wt.% Co materials were densified using a WC and Co powder. The WC-Co almost completely dense with a relative density of up to 99.5 % after the simultaneous application of a pressure of 60 MPa and an electric current for 3 minutes almost without any significant change in the grain size. The average grain size of about $0.3{\mu}m$. The hardness and fracture toughness at $1000^{\circ}C$ were about $2200kg/mm^2$ and $9.8MPa.m^{1/2}$, respectively.

An experimental study on effectiveness of group decision support systems in diea-generation (아이디어 도출단계에서의 그룹의사결정지원시스템 효과성에 관한 연구)

  • ;;;;Kim, Sun Uk;Park, Jong Hak
    • Journal of the Korean Operations Research and Management Science Society
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    • v.20 no.1
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    • pp.11-26
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    • 1995
  • We have used various information technologies (IT) in group decision-making for increasing effectiveness and satisfaction of group decision-making process. Recently, a new form of IT so called Group Decision supprot System (GDSS) was introduced into group decision-making process. Previous experimental studies about effectiveness of GDSSS have been inconsistent and the results were mixed. There was no empirical studies about GDSS in Korea. In this study, we divide two groups-GDSS supported group and traditional face-to-face group and investigate impacts of GDSS on group decision-making processes and outcomes. An idea generation task for operational action plan development, implementing GEO's strategic vision, served as the decision-making context. Supported GDSS is GroupSystems V, which had been developed by Univ. of Arizona. It was translated by Korean. According to the results, Number of nonredundant ideas in GDSS group is two or three times more than Non-GDSS grop. GDSS group feel more equal status, have better interpersonal relationship, have more confidence on group decision than Non-GDSS group. But satisfaction of participants on decision-making process and outcome has not showed a significant difference between two groups. Because all of participants in GDSS group were novice to GDSS. With this results we suggest further studies on transforming western type GDSS to Korean decision-making culture. It will be cornerstone for development of GDSS in Korean desision-making culture. It will be cornerstone for devlopment of GDSS in Korean decsion making culture environment.

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A Study on the Utilization of Instructional Materials in Dental Health Education. (구강보건교육에 있어서 교육재료 활용에 관한 연구)

  • 정영숙
    • Korean Journal of Health Education and Promotion
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    • v.2 no.1
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    • pp.113-121
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    • 1984
  • How can the educator help learners to learn? The old way was to tell learners as much as possible, passing on the educator's knowledge. Now the educator acts as a helper. She will organise experiences which allow the learners to do health behaviors, she may utilize instructional materials, she may write downsome questions for a group of learners to discuss. In all these ways the teachers is helping learning. Some educators feel that they must do all the talking themselves. They feel that they are not really teaching the learners some new information, but this is quite wrong. In fact if a educatorgives a lecture and learners do not learn, then the educator is talking not teaching. So the devlopment of instructional materials is much needed to be a learner education. And the selection of materials may be very important for the level of maturity of the learners in interest, complexity of ideas, opportunity for self-identification, speed of learners' ability to observe and length of concentration. Author studied the several instructional materials which can be utilized in the field of dental health education and also studied their values, limitations and considerations when they are used. The learning activities are poster, puppet, model, mock-up, specimen, flannel board, chalk board, bulletin board, psychodrama, role play, field trip, exhibition, laboratory method.

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A pilot study for restandardization of CDI( Child Development Inventory) in Korea (K-CDI 아동발달검사 표준화를 위한 예비연구)

  • Kim, Jeong-Mee;Shin, Hee-Sun
    • Child Health Nursing Research
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    • v.12 no.2
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    • pp.260-267
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    • 2006
  • Purpose: This pilot study was to develop Korean version of CDI(The Child Development Inventory) and assess the validation and reliability on K-CDI. Method: The K-CDI is assessed by parent-report method that has designed to screen children developmental functioning on 12 months to 6.5 years of age /or older children who are judged to be functioning in the one to six-year range. The inventory assesses areas of child development in the social, self-help, motor, language, letter and number skills. also, it includes various symptoms and behavior problems that young children may have. Participants were 130 children and their mothers who has lived in Seoul or Gyounggi-Do. Data was analyzed on the ratio of item response, Pearson's correlation, and Cronbach alpha. Results: 270 items with 8 sub-developmental realms were confirmed the reliabilities and validity on Korean children. Total 300 items were selected for restandardization. There was a significant correlation between the score of Social Maturity Scale and K-CDI. The corrlation coefficient alpha was .98. Conclusion: This study indicated that CDI is applicable in the clinical and early childhood educational setting for developmental assessment in Korea.

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