• Journal of Nutrition and Health
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• 제56권6호
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• pp.655-666
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• 2023

Purpose: Gestational nutrition has an impact on the growth and development of the fetus. Choline (C) and docosahexaenoic acid (DHA) are important and essential nutrients for humans that play a role in the structural integrity of the membranes as well as signalling. C is used in the synthesis of phosphatidylcholine, and cell membranes are highly enriched with DHA. The dietary intake of C or DHA during pregnancy directly influences fetal development. Currently, there is no evidence to prove the effectiveness of the combined dietary supplementation of both C and DHA during gestation on developmental outcomes in the offspring. Methods: The current study was designed to assess the physical, sensory, and motor development of rat pups born to mothers supplemented with C and/or DHA during the entire gestational period. Pregnant rat dams were divided into the following five groups: Normal control (NC), Saline control (SC), Choline (C), DHA, and Choline+DHA (C+DHA). The NC dams did not receive any supplementation during the entire gestation period. The experimental groups were supplemented with Saline, C, and/or DHA, respectively, during the entire gestation (E0 to delivery). Results: Rat pups (n = 6/group) exposed to combined C and DHA showed significant improvement in birth weight, fur development, eye-opening as well as weight gain on the 7th, 14th, and 21st postnatal day and pinnae detachment (assessed from birth to postnatal day 21) when compared with age-matched NC, SC or C or DHA pups. Further, significant reflex responses were observed in visual placing and bar holding of pups exposed to both C and DHA, whereas the differences in surface righting, negative geotaxis, and grasping reflexes were not significant between the groups. Conclusion: Gestational supplementation of both C and DHA rather than either of them alone is better in enhancing developmental outcomes in rat pups.

• 한국응용곤충학회지
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• 제41권3호
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• pp.199-204
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• 2002

전남 고흥지역의 유자과원에 발생하는 글응애와 그 우점천적인 O.kashmirica benefica의 발생소장과 온도별 발육특성, 발육영점온도 그리고 유효적산온도를 1997년부터 2000년까지 4년동안 조사하였다. 15, 20, 25, 3$0^{\circ}C$ 항온조건에서, 알부터 우화까지 발육기간은 각각 67.3, 31.4, 19.4, 15.3일이었고, 각 태별로는 번데기, 알, 3령 유충, 2령 유충, 1령 유충 순으로 발육기간이 길었으며, 암성충의 일평균산란수는 각각 3.3, 5.6, 7.3, 7.7개로 온도가 높을수록 산란수는 증가하였으나, 부화율과 우화율은 $25^{\circ}C$에서 각각 92%와 60%로 가장 높았다. 성충 수명은 암컷이 54.3일, 수컷이 58.6일로 숫성충이 약간 길었고, 자연발생 상태에서 성비는 0.58이었다. 알, 1령 ,2령, 3령 유충, 번데기 그리고 알에서 번데기까지의 발육영점온도는 각각 12.7, 10.0, 10.8, 7.9, 10.1, 10.6$^{\circ}C$였고, 유효적산온도는 41.4, 22.9, 22.7, 46.6, 165.3, 292.9일도였다. O.kashmirica benefica는 유자과원에서 4월 상순부터 12월 상순까지 발생하고, 발생최성기는 글응애 발생량에 의존하여 해에 따라 다르며 발생최성기에 글응애와의 비율은 100-200:1이었다.

• 한국응용곤충학회지
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• 제37권2호
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• pp.193-198
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• 1998

유자(Citrus junos T.) 과원의 주요 해충의 귤응애(Panonychus ？갸 M.)의 발생소장, 온도별 발육기간, 산란수, 부화율 및 유자유목의 생육에 미치는 영향을 구명하고자 1996년부터 1997년까지 2년간 조사한 결과, 귤응애는 5월부터 11 월까지는 발생하였는데 년 2회의 발생최성기를 이루었다. 1차 발생최성기는 7~8월이고, 2차발생최성기는 10월이었다. 2차 발생최성기에는 잎당밀도 9.5마리로 연중 최대발생량을 보였다. 유자 잎에서 귤응애의 각 태별 구성비는 난, 약충, 성충이 각각 85, 9, 6%로 난의 비율이 월등히 높았다. 15, 20, 25, $\pm$1$^{\circ}C$(RH 60 $30\pm$10%, 14L-10D)의 항온조건에서 난부터 성충까지 발육기간은 각각 41.1, 15.5, 11.0, 9.4일이고 성충수명은 23.3, 8.3, 6.3, 6.1일로 온도가 높을수록 발육기간과 성충수명은 짧아지는 경향이고 부화율은 $30^{\circ}C$에서 94.7%로 가장 높았다. 일평균 산ㄹ나수는 $25^{\circ}C$에서 4.5개로 가장 많았다. 또, 귤응애 방제밀도에 따른 유자유목의 생육상황은 방제밀도가 낮을수록 간주 및 수관용적 증가량이 많았고 엽록소함량도 많았다. 월동후 낙엽율은 1, 3, 6마리/잎, 무방제에서 각각 13.5, 20.6, 53.1, 72.6%로 잎당 성충밀도 3마리 이하에 방제하는 것이 낙엽율이 낮았다.

• Reproductive and Developmental Biology
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• 제38권4호
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• pp.143-146
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• 2014

Antioxidants, as reactive oxygen species scavengers, are one of the beneficial additives in serum-free defined culture medium. In this study, three separate experiments were performed to determine the effects of 3-hyroxyflavone added to the culture medium on the developmental competence of follicular bovine oocytes during in vitro maturation (IVM) and/or in vitro culture (IVC). The rate of blastocyst developed from oocytes cultured in IVM medium with 3-hyroxyflavone was significantly higher than that from control oocytes (39.0% vs. 26.3%, p<0.001), respectively. However, oocytes cultured in the medium with addition of 3-hyroxyflavone only at IVC period did not show significance in the blastocyst development when compared with control. When 3-hyroxyflavone was added to both IVM and IVC media, the rate of blastocyst formation was even significantly lower (21.1%) than control (26.5%; p<0.05). The present findings suggested that antioxidative activity of 3-hydroxyflavone added to only IVM medium beneficially affected the developmental competence of follicular bovine.

• 한국토양동물학회지
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• 제5권2호
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• pp.119-123
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• 2000

변온조건이 파밤나방 (Spodoptera exigua (H bner)) 유충과 영의 발육에 미치는 영향이 분석되어졌다. 정온조건에서 사육하였을 때 발육영점온도는 발육태와 유충영기에 따라 다르지만 평균 13$^{\circ}C$로 추정되었다. 이 발육영점온도를 기준으로 동등한 일일유효온도를 갖는 세 가지 다른 발육 온도조건을 설정하였다. 정온조건에 비해 변온조건은 발육속도를 뚜렸하게 변화시켰다. 동일한 최고온도(2$0^{\circ}C$)를 가졌던 두 가지 일일 변온조건중에서 저온기간이 상대적으로 높았던 조건(1$0^{\circ}C$)은 발육속도를 촉진시킨 반면 저온기간의 온도가 낮았던 조건(5$^{\circ}C$C)은 오히려 저해효과를 나타냈다.

• 한국지구과학회지
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• 제23권2호
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• pp.154-165
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• 2002

The purpose of this study was to examine the effects of metastrategic exercise on a scientific reasoning strategy to control variables, and investigate the developmental patterns in the strategy usage within a given period. Two groups composed of 90 fifth grade students engaged in a scientific reasoning task over six daily sessions. Additionally, one group engaged in metastrategic exercise on fictional students' strategies of controlling variables on the task, while the other spent equivalent time on an unrelated task. Based upon results of the study, the following conclusions can be drawn. First, the metacognitive exercise on the strategy to control variables has positive and long-standing effects on the strategy performance at the reasoning task. The exercise also takes effect of near-transfer. Taking into consideration only about sixty minutes of metastrategic practice, the results provide the validity of the activity in order to develop children's reasoning strategies. Second, in a scientific reasoning task, each child seems to go through one out of two developmental patterns in their usage of reasoning strategies: gradual change or fundamental change. Considering the ratio of pattern of fundamental change between the two groups, it is clear that the metacognitive exercise influences the developmental pattern of strategy usage.

• 한국발생생물학회:학술대회논문집
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• 한국발생생물학회 2001년도 전기 제11차 학술대회 논문집
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• pp.46-49
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• 2001

R. Philippinarum is dioecious and oviparous. In the early vitellogenic oocyte, the Golgi apparatus and mitochondria present in the perinuclear region are involved in the formation of lipid droplets and in lipid granule formation. In the late vitellogenic oocyte, the endoplasmic reticulum, mitochondria in the cytoplasm are involved in the formation of proteid yolk granules. At this time, exogenous lipid granular substance and glycogen particles in the germinal epithelium are passed into the ooplasm of oocyte through the microvilli of the vitelline envelope. Ripe oocytes are about 55-60 $\mu$ m in diameter. The spawning period was once a year between early June and early October, and the main spawning occurred between July and August when seawater temperature was approximately 20 C. The reproductive cycle of this species can be categorized into five successive stages: early active stage (February to March), late active stage (April to May), ripe stage (April to August), partially spawned stage (June to October), and spent/inactive stage (August to March). Gonad developmental phases by histological qualitative analysis showed similar results with those of quantitative image analysis.

• 동의생리병리학회지
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• 제21권4호
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• pp.1025-1029
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• 2007

It is widely assumed that Intelligence Quotient (IQ) is determined by inherent disposition and environmental factor. IQ is estimated by age-conversion score and stabilized around age 4 and IQ of adult age can be predicted after age 10. Though children with Mental Retardation (MR) are delayed in language development since early infant period, they receive only special education including speech and language therapy, but no special medication. In traditional Korean medicine, the etiology and treatment for developmental delay of language have been handed down for a long time. Some studies on herbs and prescriptions for improving language development have been undertaken recently. We have found several cases of significant elevation of IQ in the children treated with long term medications of Korean herbal medicine for improvement of language. Analyzing these cases, especially performance IQ showed significant change. Therefore we suggest that Korean herbal medicine might improve cognition development in children with MR.

• Child Health Nursing Research
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• 제28권1호
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• pp.70-81
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• 2022

Purpose: This study aimed to develop and evaluate the effectiveness of an educational program on developmental positioning (EPDP) for nurses in neonatal intensive care units (NICUs). Methods: The study utilized a non-equivalent control group pretest-posttest design. Sixty NICU nurses were recruited from two university hospitals in Daejeon, South Korea. The EPDP consisted of a 7-week program: 3 weeks of education and practice, followed by 4 weeks of encouragement messages using social networking services. Developmental positioning (DP) posters and DP aids were also provided during the intervention period. The intervention group (n=30) received the EPDP, but not the control group. The data were analyzed using the 𝜒² test, the Fisher exact test, the independent t-test, and repeated-measures analysis of variance. Results: Participants' knowledge (t=7.49, p<.001), attitudes (t=1.99, p=.001), self-efficacy (t=2.99, p=.004), performance of DP (t=2.98, p=.004) and Infant Positioning Assessment Tool (IPAT) scores (F=29.50, p<.001) were significantly higher in the intervention group than in the control group. Conclusion: The EPDP can be an effective and useful program for improving the performance of DP among NICU nurses by increasing their knowledge, attitudes, and self-efficacy of DP. However, further research involving various NICU settings is needed to gather more empirical evidence.

• Parasites, Hosts and Diseases
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• 제29권2호
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• pp.149-160
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• 1991

한국산 마우스로부터 분리한 크링토스포리디움(Cryptosporidium)의 대형 오오시스트 (C. muris)를 SPF 마우스에 경구 투여하여 분변 내 오오시스트 배출 양상과 투과전자현미경으로 위선 조직에서 발견되는 여러 발육기의 미세구조를 관찰하였다. 마우스에 있어서 prepatent period는 평균 5.6일, patent period 63.0±1.6일, 오오시스트 배출 정점기는 투여 후 36.6±2.8일째, 그리고 일반적으로 30일부터 50일까지 20일간에 걸쳐 다수의 오오시스트가 분변으로 배출되었다. 이 원충의 거의 모든 발육기의 크기는 C. Parwum보다 커서 오오시스트 1.4배, 스포로조이트 2.4배, 메로조이트 1.6배, 수생식체 1.5배이었다. 그리고, 숙주세포에 부착되어 있는 부위는 C. parwum의 것과 현저하게 다르므로 모든 발육기에서 바같쪽이 숙주의 두터운 사상돌기로 둘러싸여 있는 전단 돌출부를 볼 수 있었다. 또한, 한국산 마우스 유래 오오시스트가 strain RN 66의 것보다 다소 작았다. 이상의 결과를 기초로 하여 한국산 마우스 유래 크립토스포리디움을 C. maris라고 동정하였으며, Cryptesporidium tsuris(strain MCR)라고 명명하고자 한다.