• PNF and Movement
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• v.16 no.3
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• pp.485-493
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• 2018

Purpose: This study provides a treatment for central nervous system development in patients with chronic stroke by investigating changes in the upper limb function over time. The correlations among the activities, participation, and environmental factors of the international classification of functioning (ICF), disability and health are also examined. Methods: The subjects of this study are 18 patients with chronic stroke who were hospitalized and treated at 00 hospital in the Chungcheongbuk-do province. Their upper extremity functions are evaluated using the manual function test (MFT). The activities, participation, and environmental factors are evaluated using the ICF generic form. The correlations between the total scores of the affected and unaffected sides and the ICF items are analyzed using the Pearson correlation analysis. The significance level is p<0.05. Results: When the correlations between the activities and participation areas of ICF and the total score of the affected side of MFT were examined, significant correlations (p<0.05) were found in the following items: changing basic body position (D410), lifting and carrying objects (D430), moving around using equipment (D465), using transportation (D470), washing oneself (D510), caring for body parts (D520), and dressing (D540). When the correlations between the activities and participation areas of ICF and the total score of the unaffected side of MFT were examined, significant correlations (p<0.05) were found among writing (D170), speaking (D330), eating (D550), and drinking (D560). In addition, when the correlation between the environment area of ICF and the total score of the unaffected side of the MFT were examined, significant correlations (p<0.05) were found between products and technology for personal use in daily living (E115) and immediate family (E310). Conclusion: The MFT of patients with chronic stroke is closely correlated with the activities, participation, and environmental factors of ICF. This result suggests that ICF can be used as a useful tool to comprehensively evaluate the abilities of the patient, including the upper extremity function.

• Journal of the Korean Society of Environmental Restoration Technology
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• v.22 no.1
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• pp.13-31
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• 2019

Green spaces are recognised for the benefits. They bring to the quality of people's lives. However, since the 1980s there has been a general increase in poorly-managed green spaces. In an attempt to address this issue, green space policy has changed its focus on green space management through the gradual introduction of green space evaluation tools, such as the Green Flag Award (GFA). The GFA, as an established green space evaluation tool in the UK, reflects a shift in policy drivers of green spaces management. However, there is a lack of research investigating the contextualisation between a wide range of policy contexts and such green space evaluation tools (the GFA in this study). The aims of this study are therefore to explore the development of green space evaluation since the late 1990s, with respect to the growth of the GFA and its impact on other evaluation tools across the UK and several countries. To address the aims, this study employs in-depth literature reviews on UK green space policy mainly conducted by government. In addition, case studies are presented, focusing on the GFA and independent green space evaluation tools intrinsically derived from the GFA in the UK's cities and Nordic countries. Results show that based on the awareness of the severity of declining standards of green spaces, newly emerging policy arrangements have been adopted to address negative issues, which affect the standard of green spaces such as the transfer of responsibility for green space management, the implementation of Compulsory Competitive Tendering and ongoing budget cuts. Significantly, the GFA's indicators reflect the emerging changes of economic and social contexts associated with green spaces management where, in particular, the prospect of continuous budget cuts, which encourages communities to become involved in green space management. The GFA has widely contributed to leading such UK's cities and other countries to be able to create their independent green space evaluation tools in different approaches based on stakeholders' (mainly community) involvement in the decision-making process of green space evaluation. In conclusion, this study implies that successful green space evaluation tools do embody the value of green spaces and address drivers of emerging green space management with correspondence to the context of policy arrangements. Importantly, stakeholders have an opportunity to be involved in a partnership in the decision-making process through some green space evaluation tools. It is hoped that for well-managed green spaces this study will contribute valuable knowledge to our existing understanding of green space management in an era of austerity.

• Journal of Life Science
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• v.29 no.5
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• pp.621-630
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• 2019

Fertilization is the beginning of a new life that occurs in the female uterine. The female reproductive tract is composed ovary, oviduct, uterine, vagina and cervix, their physiological features are regulated by estrous cycle. Of these, uterine is a main point to establish embryo development and implantation, and intercommunication between embryo and uterine environment is necessary for suitable pregnancy. Endometrium is part of the uterine, its morphology is repetitively changed by hormones, and characteristic of uterine fluid from endometrium is also changed. Recently, massive proteins of endometrium and uterine fluid can be detected according to develop proteomics and bioinformatics and have been accelerated the understanding of the reproductive biology fields. Moreover, the massive protein information is actively studying with deeply studied theory such as sex hormone signal pathway and angiogenesis in mammals. In this paper, we review understanding of endometrium remodeling, uterine gland and fluid during estrous cycle, additionally studies on endometrium and uterine fluid based on proteomics techniques. Lastly, we introduced methods of the protein-protein correlation using bioinformatics tool that interaction with hormone receptors, representative angiogenetic factors and detected proteins using proteomics in endometrium and uterine fluid. This review will be useful to understanding the study on search of new cell mechanism in endometrium and uterine fluid.

• Journal of Food Hygiene and Safety
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• v.34 no.3
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• pp.269-276
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• 2019

A colorimetric rapid detection method based on acetylcholinesterase (AChE) was developed for the analysis of organophosphorus (OP) and carbamate (CB) pesticides. The AChE catalyzes acetylthiocholine into thiocholine having (-) and (+) charges, and the (+) charge results in gold nanoparticle (GNP) aggregation. The in-activation of AChE by OP and CB has been well known. In order to optimize the colorimetric method, optimal dilution times of commercial serum containing AChE, diameter of GNP, and concentration of acetylthiocholine were tested as a key parameter. The colorimetric detection limits of the method were 7.5 ng/mL for both dimethyl amine and carbofuran pesticides in 60% ethanol. No cross-reaction to other chemicals, such as aflatoxin B1 and ochratoxin A, which can be contaminated with pesticides in agricultural products, was observed. Recoveries from lettuce, sesame leaf, and cabbage lettuce spiked with known concentrations of dimethyl amine and carbofuran were found to be ranged from 83.85 to 133.16%. These results indicated that the colorimetric rapid method based on AChE can be a useful tool for the sensitive, specific, rapid, and accurate detection of OP and CB pesticides in fresh vegetables.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.32 no.2
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• pp.68-93
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• 2019

Objective : This study summarized the characteristics of clinical trials for atopic dermatitis medicines approved by the Ministry of Food and Drug Safety(MFDS). This study may be a reference for the design of clinical trials of atopic dermatitis herbal medicine treatment which may be carried out later. Method : The characteristics of the clinical trial were analyzed for clinical trials registered with ClinicalTrials.gov, CRIS, and the Korea Health Industry Development Institute among the clinical trial approval statuses posted on the website of the MFDS. Result : 1. Clinical trial drugs were developed in various formulations such as oral medicines, injections, dermatologic agents, and similar proportions. Relatively little clinical trials were found for herbal medicine. 2. In the control evaluation test, most of the treatments for the control group were performed with placebo using Vehicle. 3. In most clinical trials, one intervention group was in the form of a parallel assignment with only one treatment. 4. The age of the subjects was 11 out of 28 studies including minors, and clinical trials targeting minors were also found to be significant. 5. In the case of atopic dermatitis, the cases of subacute chronic or atopic dermatitis more than 6 months or more than 1 year were often used. 6. Most clinical trials were divided into mild to moderate atopic dermatitis or moderate to severe atopic dermatitis. The SCORAD index, EASI, IGA, BSA, and NRS were used as the evaluation criteria. 7. Regulations for the drugs used prior to the trial period for the treatment of atopic dermatitis vary somewhat from one clinical trial to another. 8. IGA was used most often as a primary efficacy tool, and SCORAD index, EASI, and NRS were also used.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.12
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• pp.863-871
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• 2018

Existing vulnerability analysis tools are prone to missed detections, incorrect detections, and over-detection, which reduces accuracy. In this paper, cross-checking based on a vulnerability detection method using static and dynamic analysis is proposed, which develops and manages safe applications and can resolve and analyze these problems. Risks due to vulnerabilities are computed, and an intelligent vulnerability detection technique is used to improve accuracy and evaluate risks under the final version of the application. This helps the development and execution of safe applications. Through incorporation of tools that use static analysis and dynamic analysis techniques, our proposed technique overcomes weak points at each stage, and improves the accuracy of vulnerability detection. Existing vulnerability risk-evaluation systems only evaluate self-risks, whereas our proposed vulnerability risk-evaluation system reflects the vulnerability of self-risk and the detection accuracy in a complex fashion to evaluate relative. Our proposed technique compares and analyzes existing analysis tools, such as lists for detections and detection accuracy based on the top 10 items of SANS at CWE. Quantitative evaluation systems for existing vulnerability risks and the proposed application's vulnerability risks are compared and analyzed. We developed a prototype analysis tool using our technique to test the application's vulnerability detection ability, and to show that our proposed technique is superior to existing ones.

• Korean Journal of Cognitive Science
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• v.32 no.3
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• pp.141-167
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• 2021

Authenticity is the opposite of hypocrisy or deceitful living in philosophy. While various positive factors that humans experience in life based on authenticity have been studied abroad, most of the studies in Korea that tried to measure authenticity did not take into account the characteristics of Korean culture or were developed only for the purpose of use in a limited domain or specific purpose. In this study, based on the specificity of Korean culture, we developed a measure of authenticity that researchers can use universally. To this end, the items constituting the existing authenticity scale and the items reflecting the cultural value of Korean society, which value social relationships, are integrated. The results of exploratory factor analysis and confirmatory factor analysis indicated that authenticity consists of three factors: self-awareness, behavioral authenticity, and relationship authenticity. In addition, criterion validity was verified based on correlations with life satisfaction, mindfulness, self-esteem, HEXACO, social desirability, self-regulation focus, and emotional diversity. These results suggest that the authenticity scale of this study is a reliable and valid measure, and is expected to be an important tool for empirical individual differences research on authenticity in everyday life in Korean population.

• The Journal of the Korea institute of electronic communication sciences
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• v.16 no.4
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• pp.577-584
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• 2021

Electrical energy is an essential component in present societies, which is an important basis for our technological society. In the design of new power infrastructure, it is important to consider the psychological aspects of how our culture considers and aspects its development as an integral component of the community environment. The construction of new high voltage overhead transmission lines has become a controversial issue for public policy of government due to social opposition. The members of community are concerned about how these power lines may have an impact on their lives, basically caused by their effects on health and safety. The landscape and visual impact is one of the most impact that can be easily perceived for local community. The computer 3D simulation of new landscape is illustrated by a real life use corresponding to the selection of the power line route with least observability for local community. This paper used ArcGIS(geographic information system tool) for planning, survey, basic route and detailed route, route for implementation of transmission line corridor. Also, the paper showed the map of natural environment, living environment, safety and altitude using database of power line corridor, and transmission siting model was developed by this study. The suggested landscape of computer simulation with lowest visibility on a power line zone can contribute to reducing oppositions of local community and accelerating the construction of new power lines.

• Korean Journal of Biological Psychiatry
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• v.27 no.2
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• pp.94-100
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• 2020

Objectives Amyloid β positron emission tomography (Aβ PET) is widely used as a diagnostic tool in patients who have symptoms of cognitive impairment, however, this diagnostic examination is too expensive. Thus, predicting the positivity of Aβ PET before patients undergo the examination is essential. We aimed to analyze clinical predictors of patients who underwent Aβ PET retrospectively, and to develop a predicting model of Aβ PET positivity. Methods 468 patients who underwent Aβ PET with cognitive impairment were recruited and their clinical indicators were analyzed retrospectively. We specified the primary outcome as Aβ PET positivity, and included variables such as age, sex, body mass index, diastolic blood pressure, systolic blood pressure, education, dementia family history, Mini Mental Status Examination (MMSE), Clinical Dementia Rating (CDR), Clinical Dementia Rating-Sum of Box (CDR-SB), hypertension (HTN), diabetes mellitus (DM) and presence of apolipoprotein E (ApoE) E4 as potential predictors. We developed three final models of amyloid positivity prediction for total subjects, mild cognitive impairment (MCI) and Alzheimer's disease (AD) dementia using a multivariate stepwise logistic regression analysis. Receiver operating characteristic (ROC) curve analysis was performed and the area under curve (AUC) value was calculated for the ROC curve. Results Aβ PET negative patients were 49.6% (n = 232), and Aβ PET positive patients were 50.4% (n = 236). In the final model of all subjects, older age, female sex, presence of ApoE E4 and lower MMSE are associated with Aβ PET positivity. The AUC value was 0.296. In the final model of MCI subjects (n = 244), older age and presence of ApoE E4 are associated with Aβ PET positivity. The AUC value was 0.725. In the final model of AD subjects (n = 173), lower MMSE scores, the presence of ApoE E4 and history of HTN are associated with Aβ PET positivity. The AUC value was 0.681. Conclusions The cerebral amyloid positivity model, which was based on commonly available clinical indicators, can be useful for prediction of amyloid PET positivity in MCI or AD patients.

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.32 no.6
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• pp.553-560
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• 2020

This paper presents an algorithm for identifying and eliminating errors by seagrasses in coastal bathymetry surveying using drone and HD camera. Survey errors due to seagrasses were identified, segmentated and eliminated using a L∗a∗b color space model. Bathymetry survey using a drone and HD camera has many advantages over conventional survey methods such as ship-board acoustic sounder or manual level survey which are time consuming and expensive. However, errors caused by sea bed reflectance due to seagrasses habitat hamper the development of new surveying tool. Seagrasses are the flowering plants which start to grow in November and flourish to maximum density until April in Korea. We developed a new algorithm for identifying seagrasses habitat locations and eliminating errors due to seagrasses to get the accurate depth survey data. We tested our algorithm at Wolpo beach. Bathymetry survey data which were obtained using a drone with HD camera and calibrated to eliminate errors due to seagrasses, were compared with depth survey data obtained using ship-board multi-beam acoustic sounder. The abnormal bathymetry data which are defined as the excess of 1.5 times of a standard deviation of random errors, are composed of 8.6% of the test site of area of 200 m by 300 m. By applying the developed algorithm, 92% of abnnormal bathymetry data were successfully eliminated and 33% of RMS errors were reduced.