• Korean Journal of Radiology
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• v.23 no.11
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• pp.1078-1088
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• 2022

Objective: To develop and validate a model using radiomics features from apparent diffusion coefficient (ADC) map to diagnose local tumor recurrence in head and neck squamous cell carcinoma (HNSCC). Materials and Methods: This retrospective study included 285 patients (mean age ± standard deviation, 62 ± 12 years; 220 male, 77.2%), including 215 for training (n = 161) and internal validation (n = 54) and 70 others for external validation, with newly developed contrast-enhancing lesions at the primary cancer site on the surveillance MRI following definitive treatment of HNSCC between January 2014 and October 2019. Of the 215 and 70 patients, 127 and 34, respectively, had local tumor recurrence. Radiomics models using radiomics scores were created separately for T2-weighted imaging (T2WI), contrast-enhanced T1-weighted imaging (CE-T1WI), and ADC maps using non-zero coefficients from the least absolute shrinkage and selection operator in the training set. Receiver operating characteristic (ROC) analysis was used to evaluate the diagnostic performance of each radiomics score and known clinical parameter (age, sex, and clinical stage) in the internal and external validation sets. Results: Five radiomics features from T2WI, six from CE-T1WI, and nine from ADC maps were selected and used to develop the respective radiomics models. The area under ROC curve (AUROC) of ADC radiomics score was 0.76 (95% confidence interval [CI], 0.62-0.89) and 0.77 (95% CI, 0.65-0.88) in the internal and external validation sets, respectively. These were significantly higher than the AUROC values of T2WI (0.53 [95% CI, 0.40-0.67], p = 0.006), CE-T1WI (0.53 [95% CI, 0.40-0.67], p = 0.012), and clinical parameters (0.53 [95% CI, 0.39-0.67], p = 0.021) in the external validation set. Conclusion: The radiomics model using ADC maps exhibited higher diagnostic performance than those of the radiomics models using T2WI or CE-T1WI and clinical parameters in the diagnosis of local tumor recurrence in HNSCC following definitive treatment.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38C no.3
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• pp.227-232
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• 2013

Due to the development of ITS technology, various services related to transportation under vehicular environments have been provided. Especially, as wireless communication technology, WAVE has been established as a standard for vehicle-to-vehicle communications. WAVE has fast connection and excellent mobility characteristics. A VSC-A project is conducting by global automotive OEMs in USDOT. This project introduces the advanced safety services with vehicle-to-vehicle communications. In this paper, we presented the scenario of a do not pass warning service, which prevents an accident during overtaking activity by using vehicle-to-vehicle communications. In addition, we analyzed network performance under WAVE. In conclusion, we introduced the simulation results. Finally, we summarized the communication range and delay values for consideration factors for a overtaking model.

• Journal of Korean Society for Atmospheric Environment
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• v.31 no.5
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• pp.411-429
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• 2015

The Korea Ministry of Environment has established an air quality standard for $PM_{2.5}$ in 2012 and it is effective from January 2015. In this study, we review various aspects of $PM_{2.5}$ in China, including its measurement, modeling, source apportionment, and health effect, and suggest future research directions for $PM_{2.5}$ studies in Korea. Measurements studies for $PM_{2.5}$ have examined organic marker compounds and $^{14}C$ as well as inorganic aerosols for distinguishing sources. Modeling results supported that the control of $PM_{2.5}$ pollution in big city needs effective cooperation between city and its surrounding regions. The major $PM_{2.5}$ sources in China have been identified to be secondary sulfur, motor vehicle emissions, coal combustion, dust, biomass burning, and industrial sources, however, they have seasonal dependency. Especially, the severe haze pollution event during January 2013 over eastern and northern China was driven to a large extent by secondary aerosol formation. Short-term exposure to $PM_{2.5}$ is strongly associated with the increased risk of morbidity and mortality from cardiovascular and respiratory diseases, as well as total non-accidental mortality. Considered previous $PM_{2.5}$ studies in China, analysis of specific organic species using online measurement, chamber experiment for secondary aerosol formation mechanism, and development of parameterizing this process in the model are needed to elucidate factors governing the abundance and composition of $PM_{2.5}$ in Korea.

• Korean Journal of Human Ecology
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• v.14 no.4
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• pp.653-663
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• 2005

The society advance of a development of the science technique and women from the industrialization, women prefered the tailor-made clothes to the convenient ready-made clothes in the aspect to be economic and save time in the clothing habits. After marriage, middle age women change the comparison of their body due to the pregnancy and birth, the body girth of them increases compared with young woman, the winding of the waist comes to be small and they show the feature of body which the vibration thickness and the brachial girth grows bigger. The reason is that the problem on the fitness of the ready-made clothes comes into being. According to this result which analyzes a ready-made clothes body of the jacket-brand which does the middle age woman to the target in research, actual purchasing age appears than the age which most companies do to the target so that it is high, and though the body is divided in KS standard, the measurement distinguished without the body and most companies were producing the jacket. There was many case to select a fitting model Among a designer or within firm employee with the similar body and measurement. It was revealed that high rate of mending relation of a sale jacket of the company. Research about the body of the ready-made clothes is thought by continuing over there.

• The Journal of Engineering Geology
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• v.18 no.1
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• pp.69-81
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• 2008

Landslide researches are divided to a method of interrelationship for various factors, method of predicting landslide possibility, and method of estimating landslide risk which are occurring landslides in the natural slope. Most of landslides occurred in natural slope are caused by a heavy rainfall in summer season. Weathered soil layer located in upper side of rock mass was occurred. As well as, they are announced to have an influence to geometry, geology, soil characteristics, and precipitation in the natural slope. In order to investigate and interpret the variety of landslides from field investigation to risk analysis, landslide analysis process due to geotechnical and geological opinions are systematically demanded. In this research, the study area is located in Macheon area, Gyeongsangnam-do and performed the landslide investigation. From the results of landslide investigation and analysis, optimized standard model based on natural landslide is proposed to high technical method of landslide investigation and interpretation.

• Journal of Environmental Impact Assessment
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• v.18 no.3
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• pp.151-160
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• 2009

In order to use fundamental data for conservation of species diversity and stream health with dam development, fish investigation in up- and downstream of Pyeonglim Dam was seasonally conducted in 2007~2008. In addition, data of water qualities, investigated for environmental impact assessment, were used to determine a water quality standard level in Pyeonglim Stream, and it revealed that water environment condition was good in the stream. During the study period, a total number of fish caught from the 4 study sites was 5,449 representing 9 families 25 species, and there were 8 Korean endemic species (32.0%) including Rhodeus uyekii, Squalidus gracilis majimae, and Microphysogobio yaluensis. Two species of Zacco temminckii (37.5%) and Zacco platypus (26.3%) were dominant and subdominant in all sites. There were few individuals of the $2^{nd}$-class endangered species (Sand lamprey, Lampetra reissneri) and the introduced species (Bluegill, Lepomis macrochirus), found in the upstream of the dam. and further investigation for conservation of the endangered species and for prevention of the introduced species is needed in future. With fish fauna and multi-metric health assessment model in each sampling attempt, index of biotic integrity(IBI) was evaluated and it resulted mostly in good(26~35) and excellent(36~40) condition in all sites. The results indicate that it is very important to study not only environmental impact assessment with fish composition but also stream health assessment in order to conserve healthy aquatic ecosystem.

• Journal of Microbiology and Biotechnology
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• v.24 no.9
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• pp.1216-1225
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• 2014

Biofilm-related infections of Candida albicans are a frequent cause of morbidity and mortality in hospitalized patients, especially those with immunocompromised status. Options of the antifungal drugs available for successful treatment of drug-resistant biofilms are very few, and as such, new strategies need to be explored against them. The aim of this study was to evaluate the efficacy of phenylpropanoids of plant origin against planktonic cells, important virulence factors, and biofilm forms of C. albicans. Standard susceptibility testing protocol was used to evaluate the activities of 13 phenylpropanoids against planktonic growth. Their effects on adhesion and yeast-to-hyphae morphogenesis were studied in microplate-based methodologies. An in vitro biofilm model analyzed the phenylpropanoid-mediated prevention of biofilm development and mature biofilms using XTT-metabolic assay, crystal violet assay, and light microscopy. Six molecules exhibited fungistatic activity at ${\leq}0.5mg/ml$, of which four were fungicidal at low concentrations. Seven phenylpropanoids inhibited yeast-to-hyphae transition at low concentrations (0.031-0.5 mg/ml), whereas adhesion to the solid substrate was prevented in the range of 0.5-2 mg/ml. Treatment with ${\leq}0.5mg/ml$ concentrations of at least six small molecules resulted in significant (p < 0.05) inhibition of biofilm formation by C. albicans. Mature biofilms that are highly resistant to antifungal drugs were susceptible to low concentrations of 4 of the 13 molecules. This study revealed phenylpropanoids of plant origin as promising candidates to devise preventive strategies against drug-resistant biofilms of C. albicans.

• Journal of the Korean Society for Precision Engineering
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• v.19 no.7
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• pp.171-179
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• 2002

STEP-NC is the next generation CNC controller taking STEP-based data model as the interface scheme (or language) between CAM and CNC, and carrying out various intelligent functions. At the moment, efforts are being made worldwide to establish international standard for the new interface scheme formalized as ISO14649. As the new language is being established, increasing attention is being paid to the development of the new CNC. Korea STEP-NC is an integrated STEP-NC system taking ISO 14649 as an input, and carrying out various intelligent functions. It is composed of 5 modules: 1) Shop Floor Programming System (PosSFP), 2) Tool Path Generator (PosTPG), 3) Tool Path Viewer (PosTPV), 4) Man Machine Interface (PosMMI), and 5) CNC Kernel (PosCNC). Distinguished from other prototypes (of Europe and USA), the Korea STEP-NC is top-down designed, and bottom-up implemented comprehensively incorporating all the crucial components for realizing the full benefit of STEP-NC paradigm, without using any existing commercial CAD/CAM systems and CNC kernels. The Korea STEP-NC prototype was successfully demonstrated and evaluated in the ISO conventions Together with prototypes of Europe and USA, Korea STEP-NC will be used as a reference system fur the Triangular Conformance Test to be jointly carried out by ISO TC184 SC1, SC4, and IMS Project.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.35 no.12
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• pp.1351-1358
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• 2011

To approximate the threshold of the fault detection and diagnosis (FDD) system, validation of the measurements is mandatory. Naturally, the system shows uncertainties due to measuring sensors - mostly thermocouples or RTDs - and due to repeatability. The uncertainty of a thermocouple comes from natural variation or a drift of the thermocouple measurement. Considering the natural variation behaves like zero-mean white noise, its natural variation can be characterized closely by the steady-state standard deviation. However, residuals between measurements and no-fault references in FDD systems show a statistical distribution with various uncertainties. In this paper, steady-state variations of measurement residuals were investigated by utilizing built-in temperature sensors in a heat pump for the model development and the final application.

• Transactions of the Korean Society of Automotive Engineers
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• v.22 no.3
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• pp.250-256
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• 2014

EV(Electric Vehicle) has many benefits such as prevention of global warming and so on. But due to driving source changing from combustion engine to battery and e-motor, new R&D difficulties have arisen which changing of desired vehicle performance and multidisciplinary design constraints by means of strong coupled multi-physics domain problems. Additionally, dynamics performances of EV becomes more important due to increasing customer's demands and expectations for EV in compare with internal combustion engine vehicle. In this paper suggests model based development platform of EV through integrated simulation environment for improving analyse & design accuracy in order to solve multi-physics problem. This simulation environment is integrated by three following specialized simulation tools IPG CarMaker, AVL Cruise, DYMOLA that adapted to each purpose. Furthermore, control algorithm of TV(Torque Vectoring) system is developed using independent driven e-motor at rear wheels for improving handling performance of EV. TV control algorithm and its improved vehicle performances are evaluated by numerical simulation from standard test methods.