• Journal of Microbiology and Biotechnology
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• 제23권11호
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• pp.1500-1508
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• 2013

Ebosin, a novel exopolysaccharide produced by Streptomyces sp. 139, has obvious antirheumatic arthritis activity in vivo, and its biosynthesis gene cluster (ste), consisting of 27 open reading frames, has been identified. This paper reports our study of the gene functionality of ste8, the predicted protein product of which is homologous to some bacterial chain length determinant Wzz proteins. For characterization of Ste8, ste8 was cloned and expressed in the mutant strain E. coli 086:H2 (${\Delta}wzz$). The functional complementation of wzz by ste8 was demonstrated by the restoration of wild-type lipopolysaccharide biosynthesis and increased levels of serum resistance of E. coli 086:H2 (${\Delta}wzz$) (pET30a-ste8). To examine the function of ste8 in ebosin biosynthesis, the gene was knocked out with a double crossover via homologous recombination. The molecular weight of the ebosin derivative EPS-8m produced by the mutant Streptomyces sp. 139 ($ste8^-$) was much lower than that of ebosin, and the binding activity of EPS-8m for IL-1R decreased significantly compared with ebosin. These results demonstrate that ste8 encodes a chain length determinant (Wzz) that functions in ebosin biosynthesis.

• 벤처창업연구
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• 제7권4호
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• pp.9-20
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• 2012

본 연구의 목적은 전통시장에 대한 효과적이고 효율적인 지원 사업 전개를 위해 필요한 이론적 틀을 마련하는 것이다. 본 연구는 전통시장에 쇼핑몰 개념을 도입하여 쇼핑몰 선택요인이 전통시장 이미지와 매력에 미치는 영향을 분석하고 다시 이러한 매력이 재방문의도에 미치는 영향을 파악해 보았다. 이를 위해 쇼핑몰 선택요인으로 접근성, 주차시설, 본원적 혜택, 인적상호작용, 물리적 환경, 주변 환경 등의 요인을 파악하였고 이 같은 요소들이 이미지 매력과 평가 매력 그리고 더 나아가 재방문의도에 미치는 영향을 파악하였다. 쇼핑몰 선택요인 중, 주차시설, 물리적 환경, 주변 환경이 이미지 매력에 유의한 영향을 미쳤고 본원적 혜택, 인적상호작용, 물리적 환경은 평가 매력에 유의한 영향을 미쳤다. 시설 개선을 통해 구축하고자 한 현대적인 이미지, 세련된 이미지, 고급스러운 이미지 등의 전통시장의 이미지 매력은 전통시장 재방문의도에 유의한 영향을 미치지 않는 것으로 나타난 반면 평가 매력은 재방문의도에 유의한 영향을 미쳤다. 이 같은 결과는 전통시장 현대화의 이미지에 치중되어 있는 기존의 시장 활성화 지원 방안은 그리 효율적이지 못한다고 볼 수 있으며 전통시장 활성화를 위해서는 우선 평가 매력에 영향을 주는 쇼핑몰 선택요인에 초점을 맞추어 개선 노력을 기울일 필요가 있음을 보여준다. 즉 품질이 좋은 다양한 상품을 저렴하게 제공해야 하며, 전통시장의 방문 목적에 맞게 다양한 서비스를 제공해야 한다. 소비자들이 매력을 느낄 수 있도록 상인들은 손님들을 친절하고 신속하게 응대하고, 고객의 개별적인 관심 해결을 통해서 신뢰감을 주어야 한다.

• 한국농공학회지
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• 제42권6호
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• pp.122-129
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• 2000

The purpose of this study is to investigate both the fundamental and some higher natural frequencies and mode shapes of compressive members resting on the linear elastic foundation. The model of compressive member is based on the classical Bernoulli-Euler beam theory. The differential equation governing free vibrations of such members subjected to an axial load is derived and solved numerically for calculating the natural frequencies and mode shapes. The Improved Euler method is used to integrate the differential equation and the Determinant Search method combined with the Regula-Falsi method to determine the natural frequencies, respectively. In numerical examples, the hinged-hinged, hinged-clamped, clamped-hinged and clamped-clamped end constraints are considered. The convergence analysis is conducted for determining the available step size in the Improved Euler method. The validation of theories developed herein is also conducted by comparing the numerical results between this study and SAP 90. The non-dimensional frequency parameters are presented as the non-dimensional system parameters: section ratio, modulus parameter and load parameter. Also typical mode shapes are presented.

• Nuclear Engineering and Technology
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• 제5권2호
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• pp.115-131
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• 1973

L.S. Pontryagin의 Maximum Principle과 수직방향을 고려하지 않은 2군 화산 방정식을 우라늄농축도 범위에 제한없이 원통형원자로의 최소 임계질량문제에 적용하였다. 핵연료 장전방법에 관한한 최적 원자로는 내심부와 외심부가 최소의 농축도를 갖고 중간영역은 최대의 농축도를 갖는 3-영역식 원자로인 것으로 밝혀졌다. 상기 3-영역식 원자로를 모델로 하여 임계조건을 유도하였으며, 또한 고리원자로를 예로하여 농축도를 여러가지로 변환시키면서 임계조건의 해를 구하는 수치해석을 수행하였다. 그 결과 여러가지 임계조건중 최소의 임계질량을 갖는 경우는 중간영역에서의 최대 농축도가 1.2%이고 내심부와 외심부에서의 농축도가 0.65%일때라는 것이 판명되었다.

• Journal of the Korean Data and Information Science Society
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• 제21권5호
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• pp.901-908
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• 2010

다중회귀모형에서 변수선택법 중에서 전진선택과 후진제거의 과정을 기하학적으로 표현하는 그래픽적 방법을 제안한다. 반지름이 1인 반원의 제1사분면에는 전진선택 과정을, 제2사분면에는 후진제거 과정을 표현한다. 각 단계에서 회귀제곱합을 벡터로 표현하고, 추가제곱합 또는 부분결정계수를 벡터 사이의 각도로 나타내며 벡터의 끝을 연결할 때 통계적으로 유의하면 점선으로 표현하여 부분가설검정의 통계적 분석결과를 인지할 수 있도록 작성한다. 이 방법을 이용하면 전진선택과 후진제거 방법에 의한 최종모형을 비교 분석하고 전체적으로 모형의 적합도를 파악할 수 있다.

• The Journal of Asian Finance, Economics and Business
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• 제5권4호
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• pp.85-94
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• 2018

The cultural industry is treated as the sunrise industry in modern society. It has taken an increasing role in promoting the economic growth. Due to this, this paper attempts to explore the dynamic relationship between cultural industry and the economic growth. On the grounds of Cobb-Douglas production function, the cultural industry is regarded as a determinant such as the labor input and the capital input to impact the economic growth. Meanwhile, the quarterly datum form 2000-Q1 to 2017-Q4 are employed to perform an empirical analysis via the vector error correction model. The GDP is treated as an independent variable. The input of capital, the input of labor and the total input of cultural industry are treated as dependent variables. Furthermore, a menu of statistical approaches such as the co-integration test and the impulse response function will be used to testify the dynamic relationship between cultural industry and economic growth. Via the Johansen co-integration test, the results report that the cultural industry has a obviously positive effect on economic growth. Through the vector error correction estimation, the results also report that the cultural industry also has a significantly positive effect on economic growth, but less than that of the Johansen co-integration test. This paper provides a view that the cultural industry is a kind of a determinant to promote the economic growth. Therefore, the China's government should pay much attention to the cultural industry construction.

• 유통과학연구
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• 제13권12호
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• pp.23-31
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• 2015

Purpose - The purpose of this study is to determine consumers' awareness of hygiene and the perceived risks in the service areas of coffee shops and diners, or simply coffee shops. Research design, data, and methodology - A literature review was conducted on related publications, essays, and periodicals to find correlations among the variables. We developed a research model and hypothesis, and conducted empirical research for statistical data analysis. Results - The results satisfied adequacy standards, with GFI=0.926, AGFI=0.901, RMR=0.020, NFI=0.941, X²=403.197, and p-value=0.120. The results also displayed satisfied adequacy standards for the moderating effects of shop types, with GFI=0.998 (≥0.9 desirable), AGFI=0.998 (≥0.9 desirable), RMR=0.004 (≤0.05 desirable), NFI=0.999 (≥0.9 desirable), X²=1.572, and p-value=0.814 (≥0.05 desirable). Conclusions - A higher consumer hygienic awareness results in a better brand image. Moreover, greater perceived risk results in a worse brand image. Perceived risk is a vital determinant of brand image and it deeply influences customers' decisions to visit. Therefore, perceived risk is a vital determinant of forming a brand image and must be incorporated when devising strategies.

• The Journal of Asian Finance, Economics and Business
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• 제7권2호
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• pp.151-156
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• 2020

Small and medium enterprises (SMEs) play a very important role in developing countries. In Vietnam, SMEs operating in the field of handicrafts, besides contributing to the economy, also tasked to maintain and develop traditional handicrafts. However, accessing loans from banks of SMEs faces many difficulties. This study explores the determinants of bank lending decision for SMEs, particular, in traditional handicrafts business. Using dataset based on a survey conducted in Binh Duong province, Vietnam, we investigated to what determinant effects for loan approval. The analytical methods used include descriptive statistics for overall assessment, principal component analysis and regression to examine determinants of lending decisions. The results indicate that company's collateral was the most positive determinant to bank lending decision, follow by company's business plan. The role of company's leader is very important for banks considers to approve credit because company's leaders experience and relationship with stakeholders as well as banks have positive relations with bank's lending decision. Agreed with previous studies, the company's financial statement and company's credit history with banks are also significant determinants for lending decision. Whereas, the business environment seam unaffected lending decision as their relations is not significant..

• The Journal of Asian Finance, Economics and Business
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• 제8권5호
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• pp.211-219
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• 2021

This study examines the determinant influence of competence: motives, traits, self-concept, knowledge, and skills on work behavior and work effectiveness in government officials. The research was conducted on government officials in the province of South Kalimantan, Indonesia. This research is qualitative in nature, including the population of government apparatus in regencies and municipalities in the South Kalimantan province of Indonesia. The number of respondents in this study was 250 people. The sampling technique used purposive sampling, and Data analysis has been done using Structural Equation Model (SEM). The results showed a significant and positive influence on the determinants of competence, namely motives, traits, self-concept, knowledge, and skills on work behavior and work effectiveness of government officials; the determinant influence of competence showed a direct and indirect effect. This study also shows a mediating effect of work behavior between the determinants of competence (motives, traits, self-concept, knowledge, and skills) on the work effectiveness of government officials. This study's results are expected to provide suggestions to local governments in the South Kalimantan province of Indonesia to conduct performance appraisals for government officials apart from the performance appraisal methods that have been implemented.

• 대한안전경영과학회지
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• 제23권1호
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• pp.81-94
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• 2021

In SMEs, technological innovation is recognized as an important tool in terms of sustainable growth. This study analyzed the determinants of technological innovation by using the information of the corporate panel DB composed of local SMEs. The internal factors were added with technological innovation capacity and production capacity and the industrial cluster environment was first applied to external factors. Also, whether the industrial cluster environment influences technological innovation through R&D capabilities, the mediating effect was tested with the Sobel Test. Among the internal and external factors, the most important determinant was marketing ability, and a policy was proposed to develop measures to increase R&D capability with mediating effect. Among the technological innovation variables, which are dependent variables, the most determinant factor was the proportion of new product sales. For this, it is considered that additional research such as longitudinal research with the concept of repetition and parallax using the corporate panel DB is necessary.