• 제목/요약/키워드: design procedure

검색결과 5,159건 처리시간 0.036초

Effects of Replacing Lucerne (Medicago sativa L.) Hay with Fresh Citrus Pulp on Ruminal Fermentation and Ewe Performance

  • Sparkes, J.L.;Chaves, A.V.;Fung, Y.T.E.;van Ekris, I.;Bush, R.D.
    • Asian-Australasian Journal of Animal Sciences
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    • 제23권2호
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    • pp.197-204
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    • 2010
  • Two studies were conducted to determine the effects of replacing 30% (% in diet DM) of lucerne (Medicago sativa L.) hay with citrus pulp in Merino ewe diets: i) an in vitro study which measured ruminal fermentation; and ii) an in vivo study in which twelve Merino ewes pre- and post-lambing were fed experimental diets in a cross-over design over 120 days to evaluate effects on ewe performance (i.e. DM intake, average daily gain (ADG) and wool growth). In both the in vitro and in vivo studies, the control treatment consisted of lucerne (91.3% in diet DM), lupins (8.3% in diet DM) and phosphate (0.42% in diet DM), while the citrus pulp treatment consisted of lucerne (57.7% in diet DM), lupins (9.5% in diet DM), phosphate (0.48% in diet DM) and fresh citrus pulp (32.3% in diet DM). Data were analysed using the mixed model procedure of SAS. In the in vitro study, gas production, total volatile fatty acid (VFA) yield, proportion of propionic acid to total VFA and in vitro dry matter digestibility (IVDMD) were higher (p<0.02) in the citrus pulp treatment compared to the control treatment. In contrast, in vitro ammonia production, pH and the acetate to propionate ratio were lower (p<0.03) for the citrus pulp treatment compared to the control treatment. In the in vivo study, DM intake of ewes fed the citrus pulp diet was lower than their control ewe counterparts throughout both the pre- and post-lambing periods (928.9 vs. 1,115.0 g/d pre-; 1,285.0 vs. 1,620.3 g/d post-lambing, p<0.01), however ADG was similar (p = 0.12). Wool growth parameters and lamb performance did not differ (p>0.32) between treatments. In summary, the in vitro study demonstrated that the replacement of 30% of a lucerne diet with fresh citrus pulp improved total VFA yield, increased total gas production and improved IVDMD, while decreasing the production of ammonia, acetic acid and rumen pH. In addition, the in vivo study demonstrated that the replacement of 30% of a lucerne diet with fresh citrus pulp pre- and post-lambing decreased intake but did not affect ewe performance in terms of ADG and wool growth. These findings, of course, would be of significant interest to sheep producers endeavouring to control cost of feed ingredients whilst maintaining productivity.

수술 전 정보제공이 학령전기 편도선절제술 환아 어머니의 불안, 불확실성 및 수술 후 간호만족도에 미치는 효과 (The Effects of the Pre-Operation Provision of Information on the Anxiety and Uncertainty of Mothers with a Pre-school Child of Tonsillectomy and their Satisfaction with Post-operation Nursing)

  • 정경숙;박진옥
    • 한국콘텐츠학회논문지
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    • 제16권1호
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    • pp.158-166
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    • 2016
  • 본 연구는 수술 전 정보제공이 학령전기 편도선절제술 환아 어머니의 불안, 불확실성 및 수술 후 간호만족도에 미치는 효과를 파악하기 위한 비동등성 대조군 전후 실험연구이다. 자료수집은 S종합병원에서 편도절제술을 받은 학령전기 환아의 어머니로 실험군 19명, 대조군 20명을 대상으로 하였다. 실험군에게는 수술에 따른 통상적 교육과 함께 소책자를 이용하여 연구자와 연구 보조원이 직접 간호사실에서 1:1 개별로 평균 20분 정도 정보제공을 하였으며 대조군에게는 통상적 교육만 실시하였다. 자료분석은 빈도와 백분율, ${\chi}^2$-test, Fisher's exact test, Mann-Whitney U-test를 이용하였다. 수술 전 정보제공은 대조군과 실험군의 불안(U=104.5, p=.015), 불확실성(U=83.5, p=.002)에 유의한 차이를 보였으며, 수술 후 간호 만족도(U=109.5, p=.022)에도 유의하였다. 본 연구결과를 통하여 수술 전 정보제공은 학령전기 편도선절제술 환아 어머니의 불안, 불확실성 및 수술 후 간호만족도에 긍정적 효과가 있는 것으로 나타났으며, 추후 반복연구와 다양한 교육방법을 통한 정보제공의 효과검증이 필요할 것이다.

우리나라 여성복식의 변화에 미친 요인 연구 - 1945~1960년을 중심으로 - (A Study on the factors of Change in the Korean Dress and Personal Adornments)

  • 박길순
    • 복식문화연구
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    • 제1권1호
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    • pp.33-68
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    • 1993
  • The purpose of this paper is to survey the influence of the culture change on the dress and personal adornments, and to survey the change of factors from the August 15. 1945 to 1960, in connection with the social and cultural background, applying B. Malinowski′s "Theory of Culture Change" which means an acculturation is the change′s elements of the dress and its ornaments. It is remarkable that the dress and personal adornments of Korean women after August 15, 1945 has great change from the traditional dress of the thousands years. Through the Liveration on August 15, 1945, American military government and the establishment of the Korean government, American democracy has brought many changes on Korean society. Advancement of education, an society with developed economic life, and introduction of scientific skill have influenced on the women′s way of thinking and a style of behavior and the view of value. The acculturation, the supply of mass communication, introduction of new institution and the reorganization of the old institution, the change of the economic situation, the change of the educational system, the change of the point of value, the development of scientific skill have greatly influenced on the dress and personal adornments. Modern dress and personal adornments of Korean women has the following developing procedure. The Liberation from Japan on the 15th, of August, 1945, the stationing of American Soldiers during hte Koran War, returning of the oversea′s brethern, and the mass communication have the direct and indirect contact with western civilization, and bring the occasion of development of the modern dress of Korean women. The increase of mass communication, such as radio, TV, newspaper, magazines and the frequent fashion shows showed fine design and practical western style dress to the women. This was the real beginning of the western style dress in Korea. By the increase of employment and the improvement of the economic situation, the consumption of clothing and the adornments was increased, so that a wide variety of fashions was set, and numerous kind and form of dress came in. As the increase of the number of women students, their practical and free dress life demanded western style dress. After the Liberation from Japan, the open-door policy of sex, public morals and traditional ethics became lax, and in this disordered society, indecent expose of the body was common. By the different kind of technological development, the form, fabrics, colors and patterns in clothes were much influenced and the hair style, make up, shoes and adornments were much influenced too. As shown above, the change of the dress has the same connection with that of society and culture. This shows that the dress and personal adornments represent clearly the cultural phenomenon of the society and cultural change of the society.

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기반시설부담구역제도 제1단계 유일범역 도출과정에서의 AMOEBA 기법 적용에 관한 모의실험 연구 (A Study on the Application of the AMOEBA Technique for Delineating the Unique Primary Zones for the DIF Zoning Regulation)

  • 이석준;최내영
    • 지적과 국토정보
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    • 제47권2호
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    • pp.5-18
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    • 2017
  • 최근 기반시설부담구역 지정의 객관성 확보를 위해 핫스팟(Hotspot) 분석기법과 같이 LISA에 기초한 공간통계기법을 적용하려는 시도(Kim and Choei 2017)가 이루어진 바 있다. 그러나 Hotspot 방법의 경우 군집여부를 판별하는 통계량 생산 이후에 이 정보를 바탕으로 구체적인 범역을 객관적으로 설정하기 위한 검증된 방법론을 추가 적용할 필요가 있으며, 본 연구는 이러한 맥락에서 유일 범역의 지정을 위한 AMOEBA 기법을 그 대안으로 채택하여 이전의 Hotspot 방식과 구역지정 결과를 비교검토해 보았다. 이를 위해 분석격자단위를 100m에서 400m까지 순차 증가시키는 시나리오 분석을 수행하고 단위면적당 개발 허가 건수 및 원형도의 두 가지 평가치로 비교평가해 보았다. 분석결과, 두 방식의 수치적 평가치는 유사하였음에도, 적정 크기의 영역획정에서는 전자가, 기반시설설치 용이성에서는 후자가 다소 우월함을 보였다. 특히 유사한 평가수치와는 달리 각 방식에 의한 지정구역의 40%는 서로 상이한 지역을 획정하고 있음을 알 수 있는데, 이는 두 방식 간에 위치 적정성 판단기준에 유의미한 차이가 있음을 반증하는 것으로 보이며, 따라서 이러한 구역지정 편차의 원인과 의미를 파악하기 위한 후속연구가 필요할 것으로 판단된다.

디피리다몰 체내동태 연구를 위한 혈청 중 디피리다몰의 HPLC 정량법 개발 및 검증 (Development and Validation of an HPLC Method for the Pharmacokinetic Study of Dipyridamole in Human)

  • 조혜영;강현아;문재동;최후균;이용복
    • Journal of Pharmaceutical Investigation
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    • 제36권1호
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    • pp.45-51
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    • 2006
  • A rapid, selective and sensitive reversed-phase HPLC method for the determination of dipyridamole in human serum was developed, validated, and applied to the pharmacokinetic study of dipyridamole. Dipyridamole and internal standard, loxapine, were extracted from human serum by liquid-liquid extraction with diethyl ether and analyzed on a Nova Pak $C_{I8}$ column with the mobile phase of 40 mM ammonium acetate:methanol:acetonitrile (35:35:30)(v/v/v, pH 7.8). Detection wavelength of 280 nm and flow rate of 1.0 mL/min were fixed for the study. The assay robustness for the changes of mobile phase pH, organic solvent content, and flow rate was confirmed by $3^3$ factorial design using a fixed dipyridamole concentration (50 ng/mL) with respect to its peak area and retention time. And also, the ruggedness of this method was investigated at three different laboratories using same quality control (QC) samples. This method showed linear response over the concentration range of 2-2000 ng/mL with correlation coefficients greater than 0.999. The lower limit of quantification using 0.5 mL of serum was 2 ng/mL, which was sensitive enough for pharmacokinetic studies of dipyridamole. The overall accuracy of the quality control samples ranged from 103.94 to 105.86% for dipyridamole with overall precision (% C.V.) being 4.60-11.49%. The relative mean recovery of dipyridamole for human serum was 97.64%. Stability studies showed that dipyridamole was stable during storage, or during the assay procedure in human serum. The peak area and retention time of dipyridamole were not significantly affected by the changes of mobile phase pH, organic solvent content, and flow rate under the conditions studied. This method showed good ruggedness (within 15% C.V.) and was successfully used for the analysis of dipyridamole in human serum samples for the pharmacokinetic studies of orally administered Dimor tablet (75 mg as dipyridamole) at three different laboratories, demonstrating the suitability of the method.

염산프로메타진 체내동태 연구를 위한 혈청 중 프로메타진의 HPLC 정량법 개발 및 검증 (Development and Validation of HPLC Method for Pharmacokinetic Study of Promethazine in Human)

  • 조혜영;강현아;이화정;최후균;이용복
    • Journal of Pharmaceutical Investigation
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    • 제36권1호
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    • pp.23-29
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    • 2006
  • A rapid, selective and sensitive reversed-phase HPLC method for the determination of promethazine in human serum was developed, validated, and applied to the pharmacokinetic study of promethazine. Promethazine and internal standard, chlorpromazine, were extracted from human serum by liquid-liquid extraction with n-hexane containing 0.8% isopropanol and analyzed on a Capcell Pak CN column with the mobile phase of acetonitrile-0.2 M potassium dihydrogen phosphate (42:58, v/v, adjusted to pH 6.0 with 1 M NaOH). Detection wavelength of 251 nm and flow rate of 0.9 mL/min were fixed for the study. The assay robustness for the changes of mobile phase pH, organic solvent content, and flow rate was confirmed by $3^{3}$ factorial design using a fixed promethazine concentration (10 ng/mL) with respect to its peak area and retention time. In addition, the ruggedness of this method was investigated at three different laboratories using same quality control (QC) samples. This method showed linear response over the concentration range of 1-40 ng/mL with correlation coefficients greater than 0.999. The lower limit of quantification using 1 mL of serum was 1 ng/mL, which was sensitive enough for pharmacokinetic studies. The overall accuracy of the quality control samples ranged from 96.15 to 105.40% for promethazine with overall precision (% C.V.) being 6.70-11.22%. The relative mean recovery of promethazine for human serum was 63.54%. Stability (freeze-thaw and short-term) studies showed that promethazine was stable during storage, or during the assay procedure in human serum. However, the storage at $-80^{\circ}C$ for 4 weeks showed that promethazine was not stable. Extracted serum sample and stock solution were not allowed to stand at ambient temperature for 12 hr prior to injection. The peak area and retention time of promethazine were not significantly affected by the changes of mobile phase pH, organic solvent content, and flow rate under the conditions studied. This method showed good ruggedness (within 15% C.V.) and was successfully used for the analysis of promethazine in human serum samples for the pharmacokinetic studies of orally administered Himazin tablet (25 mg as promethazine hydrochloride) at three different laboratories, demonstrating the suitability of the method.

중소기업 M&A 의사결정 과정에 관한 연구 (Case Study on Decision-Making Process for M&A in Small and Medium Companies)

  • 정한석;문재승
    • 유통과학연구
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    • 제13권10호
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    • pp.65-72
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    • 2015
  • Purpose - A rapidly changing business environment places great demands on small and medium-sized enterprises (SMEs). These SMEs need to find strategic alternatives for continued growth and, ultimately, survival. Thus, mergers and acquisitions (M&A) are deemed an acceptable solution. Research to date has dealt with M&A in major organizations and focused on post merger integration (PMI). Our study focuses on SMEs, as they are relatively new and unknown to the public. Therefore, this study highlights successful M&A and decision making for SMEs through a case study analysis. Research design, data, and methodology - For this study, we examined an M&A case between company S, which produces cell phone parts, and company P, which produces SSD cases. We reviewed theories and previous studies in M&A literature. We comprehensively examined the decision-making procedure at each M&A stage, describing the situation of the buying company and the selling company from the period of the M&A announcement through deal completion. In addition, we conducted interviews with both companies. The data regarding this case study were collected through interviews with managers of both companies who actively participated in the M&A process. When necessary, we asked them about additional relevant information during the interviews. Results - The result of the M&A between company S and company P was deemed acceptable with the exception of the long negotiation period. However, company S was not able to prepare for PMI after the acquisition due to a controversy over acquisition values. Moreover, the employees of the newly formed company, especially those who came from company P, complained about the M&A and attempted to leave. Thus, implications for successful M&As of SMEs are as follows: First, the procedural compliance of the M&A is needed. Second, support is needed from the CEO for the working group, rather than excessive intervention during due diligence. Third, the right, talented members of the organization should be part of the process of the M&A. Fourth, the use of various types of outside expert or business consultants is needed. Fifth, the strategic intervention by Human Resource managers is required. Last, sharing M&A information among employees is important as information dissemination will help employees be more receptive to such a change. However, this study has several limitations as a single case study; more varied SME M&A case studies are needed in order to generalize the results of the study. Conclusions - Most of the research dealing with M&As has focused on major companies and PMI and neglected SMEs. Thus, our study focuses on SMEs and the decision-making procedures for M&A. This study has significantly contributed to the literature in this area and has provided practical information around the implications of sound decision-making during M&As. Specifically, the results of the study contribute to the need for research on M&A among SMEs, which to date has often been neglected as a topic of choice.

전통시장 지원에 대한 지각된 혜택과 비용이 관계품질과 지지에 미치는 영향 (Effects of Perceived Benefits and Costs of Traditional Market Support on Relationship Quality and Support)

  • 서정석;양재장;이용기
    • 유통과학연구
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    • 제12권12호
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    • pp.43-54
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    • 2014
  • Purpose - This study examines how perceived benefits and costs of traditional market support affect relationship quality and support for a marketeer. In addition, it investigates whether support for traditional market aid programs leads to support for the government. The author developed a structural model comprising several variables, in which perceived benefits and costs comprising economic, social, and environmental costs were proposed, to affect the relationship quality (satisfaction and trust) of traditional market aid programs and the government. Consequently, marketeers satisfied and trusted by traditional market aid programs and the government would support the traditional market aid program, resulting in higher support for the government. The model proposed that customer satisfaction would improve customer loyalty and business performance. Thus, the relationship quality (satisfaction and trust) of the traditional market aid program and government was proposed as a core mediating variable between perceived benefits and costs and support. Research design, data, and methodology - To analyze the proposed model, this study investigates the scenario with a traditional marketeer. Data were collected from 331 respondents, and analyzed with SPSS/PC 18.0 and AMOS 18.0. To test the unidimensionality and nomological validity of the measures of each construct, we employed a scale refinement procedure. The result of the reliability test with Cronbach's and confirmatory factor analysis warranted unidimensionality of the measures for each construct. In addition, nomological validity of the measures was warranted from the result of correlation analysis. Results - First, perceived benefit affects the relationship quality of traditional market aid programs and government. Second, perceived costs affect the satisfaction of traditional market aid programs and government. Third, the relationship quality of a traditional market aid program affects the support of a traditional market aid program, and the relationship quality of government affects the support of government. Finally, the support of traditional market aid program affects support of government. The results confirm the findings of previous studies that local development positively influences support, based on the social exchange theory. Conclusions - The theoretical and managerial contributions of this study are as follows. First, it is the first such study, and defines mediating variables, analyzing relationship quality (satisfaction and trust) between perceived benefits and costs and support for the traditional market industry. Further, it investigates the structural relationships between them with the AMOS program. Second, while most previous studies investigating the relationship between similar variables and those of the present study analyzed how perceived benefits and costs influenced support, this study identified the transfer relationship between the support for traditional market programs and support for the government. This study confirms that support for traditional market aid program increases support for the government. Therefore, government policy makers for traditional market aid programs should explain to marketeers the benefits and costs of traditional market development in terms of economic, social, and environmental factors. At the end, limitations, further research directions, and implications are suggested.

외식프랜차이즈 가맹본부의 관리특성과 공정성이 관계결속과 성과에 미치는 영향 (Relational Commitment, Performance, and the Franchiser's Management Characteristics and Fairness in Food Service Distribution)

  • 권영식;문장실;권재국
    • 유통과학연구
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    • 제12권12호
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    • pp.119-130
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    • 2014
  • Purpose - Franchise industries are significant both socially and economically. However, with increasing interest, there are manifold problems. It is necessary to seek measures for mature operation constantly despite unprepared franchisors, negative perceptions of the media and society toward franchise, and rapid changes in business start-up trends and propensity to consume that make business start-ups difficult. The paper aims to explain the effects of relational commitment and performance on the franchisor's management characteristics and justice in the food service franchise system. Research design, data, and methodology - This is an exploratory survey examining franchising in Korea. Based on a literature synthesis, we extract five constructs: managerial characteristics, support, fairness, trust, and satisfaction. We hypothesize that these factors influence the trust, satisfaction, and performance of franchisees. To examine these hypotheses empirically, we conducted a survey on the database of the Franchising Council of Korea. The study employs data from May to September 2014. In total, 135 completed questionnaires were received, of which 128 were usable. The data was analyzed with SPSS/PC 22.0. First, to test unidimensionality and nomological validity of the measures of each construct, we employed a scale refinement procedure. The result of a reliability test with Cronbach's α and factor analysis warranted unidimensionality of the measures for each construct. In addition, nomological validity of the measures was warranted from the result of the correlation and regression analysis. By analyzing the data, we can confirm most hypotheses. Results - Frist, franchisor characteristics have a positive effect on trust and satisfaction. Second, franchisor fairness has an effect on trust and satisfaction. Third, franchisor support has an effect on satisfaction. Further, the franchisee trust has an effect on satisfaction. Fourth, the satisfaction of a franchisee with a franchisor affects the performance of a franchisee. Finally, there is a possibility that not only franchisee performance but also increasing the credibility and improving the image of the franchisor through communication between franchisor and franchisee can improve franchisees' performance and satisfaction by motivating the franchisee for sustainable growth. Franchisers should endeavor for franchisees to obtain stable revenue with continuous and practical support. They should recognize that they can expand their business by supporting their franchisees. Franchisors should not only instantly respond to franchisees' troubles with interactive communications but also raise the ability of supervisors for better support. Franchisors should share their visions and goals with their franchisees and provide systematic and continuous support based on trust and clear company management. Franchisees should understand franchisors' position as well as participate in establishing the basic franchise system. Contributions - The paper contributes to understanding franchising in Korea. It offers insights and assistance to franchisors hoping to start franchises. This paper explores measurement issues related to franchisee performance by estimating its determinant factors (managerial characteristics, support, fairness, trust, and satisfaction). This study provides franchisors and practitioners planning to extend their franchising business with some practical knowledge.

곡물(穀物)의 함수율(含水率) 변화(變化)에 따른 송풍저항(送風抵抗)에 관(關)한 연구(硏究) (Resistance to Airflow of Grain as Affected by Grain Moisture Content)

  • 김만수;김성래
    • Journal of Biosystems Engineering
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    • 제11권2호
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    • pp.55-65
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    • 1986
  • The resistance to the passage of airflow through various agricultural products is an important consideration in the design of an aeration or drying system. The amount of resistance to airflow varied widely from one kind of grain to another, and depended upon airflow rate, surface texture and shape of the particles, the size and configuration of voids, and foreign and fine material in the grain bed. The airflow rate was the major factor considered on this kind of study in the early stages. But these days, the studies on the resistance to airflow of grain affected by grain moisture content and foreign and fine material have been widely carried out. However the foreign an fine material in the grain bed could not be a major factor on the study in Korea because there were only a few grain process procedure after harvesting it. The objectives of this study were to investigate the effect of moisture content and airflow rate on airflow resistance to grain, and to develop a model to predict the static pressure drop across the grain bed as a function of moisture content and airflow rate. The rough rice varieties, Akibare, Milyang 15 (Japonica types), Samkwang, Backyang (Indica types)and covered barley variety, Olbori, which were harvested in 1985 were used in the experiment after cleaning them. Resistances to airflow of grain were investigated at four levels of moisture content (13-25%, wb.) for ten different airflow rates($0.01-0.15m^3/sm^2$). The results of this study are summarized as follows; 1. Theaverage bulk densities were $585.3kg/m^3$ for rough rice and $691.6kg/m^3$ for barley at the loose fill, and were $648.8kg/m^3$ for rough rice and $758.2kg/m^3$ for barley at the packed fill. The pressure drops at the packed fill beds were approximately 1.4 to 1.8 times higher than those at the loose fill beds. 2. The pressure drops across grain beds deceased with the increase of moisture content and increased with airflow rate. The decreasing rates of pressure drop across grain beds according to the moisture contents at the lower airflow rates were higher than those at the higher airflow rates, and the increasing rates of pressure drop according to the airflow rates at the lower moisture contents were higher those at higher moisture contents. 3. The pressure drop across barley bed were much higher than rough rice beds and the pressure drops across Japonica type rough rice beds were a little higher than Indica type. 4. The mathematical models to predict the pressure drop across grain beds as a function of moisture content and airflow rate were developed from these experiments.

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