• 한방안이비인후피부과학회지
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• 제9권1호
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• pp.159-165
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• 1996

The study was clinically performed with the 128 out patients of dermatic disease who had visited the Dept. of dermatology, Dongzhimen Hospital, Beijing traditional medical college from May 2nd to February 14th 1996. The results were as follows. 1. The dermatologic findings which showed higher incidence in this study were Acne of Melasma 27 cases($21.0\%$), Psoriasis 25($19.5\%$), Eczema including Contact dermatitis 21($16.4\%$), Seborrheic dermatitis including Alopecia of hair 12($9.3\%$) and Urticaria 11($8.5\%$). 2. The sex ratio of male to female was 4.5 : 5.5. The peak incidence of age group was 30-39($21.8\%$). 3. In the duration of disease, 37 cases($28.9\%$) were between 1 year and 5 years. 27($21.1\%$) were over 10 years. 4. About the single herb drugs, they are Angelicas gigantis Radix, Paeoniae Radix and Salviae Radix in order of frequencies. In the case of pill type, Danggui gosam hwan. Chunggan hwan. Whaeo hwan and Shinnongjiyang hwan are most frequently used. In the case of topica, Whangyeongo, Juachanggo and Soeungo are used in high frequencies. 5. For the test and surgical treatment KOH surgical treatment of Molluscum contagiosum in 8 cases and the bloody treatment of Chronic psoriasis in 3 cases.

• 한방안이비인후피부과학회지
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• 제20권1호통권32호
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• pp.265-284
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• 2007

Introduction : There are three major forms of Epidermolysis Bullosa(EB) - EB Simplex(EBS), Junctional EB(JEB) and Dystrophic EB(DEB). DEB is divided into two groups that Dominant DEB(DDEB) and Recessive DEB(RDEB). RDEB has two types that Hallopeau-Siemens(generalized type) and mitis(localized type). Objects : This study was carried out to observe the progress of Recessive Dystrophic Epidermolysis Bullosa-mitis(RDEB-mitis) disease and find effective remedy. Methods: Both diagnosis and treatment were divided into three groups voluntarily. l. diagnosis - dermatic symptoms, mucosal symptoms, general symptoms 2. treatment - herbal medications, moxibustion, medicines used extemally(外用藥) Results : After treating 9 months, the condition of the patient grew better and the grades of severity of ROEB-mitis disease were lower at each diagnosis item. Conclusions : As above results, oriental medical treatments were very effective for this disease. But more case studies are necessary for establishing more effective diagnosis and treatment methods.

• 한방안이비인후피부과학회지
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• 제19권1호
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• pp.65-78
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• 2006

Background : Quality of life(Qol) is a broad concept that incorporates all aspects of an individual's existence. There is many study about Qol of the patient with dermatic disease in the west, but in korea there is few study, particularly for oriental medical academic world. Objective : The purpose of this study is to Investigate the influence of dermatic disease, particularly acne on the Qol by using the korean version of skindex-29. Method : We measured the Qol of Kyungwon university student participating in Dongseo health examination by using the Korean version of Skindex-29. A total of 535 students were enrolled In this study. Results are reported as 3 scales scores (functions, emotions, and symptoms) and a composite score (average scale score). Result : 1) There were no statistically significant gender-related differences in Qol scores in patient group with acne. 2) There were no significant correlation between Age Duration and Qol socres in patient group with acne. 3) Acne group marked higher Qol scores than contact dermatitis and normal group (lower than Acne with atopic dermatitis group) within emotional scales. 4) Acne group marked higher Qol scores than scar, tinea cruris, and normal group (lower than Acne with atopic dermatitis group) within functional and total scales. 5) Acne group marked higher Qol scores than tinea cruris and normal group (lower than Atopic dermatitis group) within symptom scales. 6) In acne group that feel the necessity of medical treatment, group that be treated by occidental medical method marked lower Qol scores than group that don't be treated within functional, symptom, and total scales. 7) In acne group that don't be treated, group that feel the necessity of medical treatment marked higher Qol scores than group that don't feel within emotional, functional, and total scales. 8) Acne group that don't fee the necessity of medical treatment and be treated marked high scores than normal group within all scales. Conclusion : Acne is sometimes thought of as unimportant, but Acne significantly affects patient's Qol. Occidental medical treatment can help Acne patients to improve Qol. Even if someone who suffering from acne feel that he don't need to be treated, he had lower Qol than healthy controls. And we can expect that proper occidental medical treatment help him. But few study have discuss whether oriental medical method can improve Qol of acne patients. From now on we expect interesting study that measure effect of oriental medical therapy on Qol of Acne patients and compare with occidental medical therapy by using Qol mesure instrument.

• 한국응용과학기술학회지
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• 제37권6호
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• pp.1698-1705
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• 2020

나이가 20-25세인 남녀 성인들 20명(남성 5명, 여성 15명)의 엄지손가락 표면에 상재하는 세균을 채취하고 Luria-Bertani agar에서 배양하였다. 배양된 세균들의 16S rDNA를 polymerase chain reaction을 통하여 증폭하고, 그 염기서열을 분석하였다. 이렇게 얻어진 염기서열을 genbank의 자료들과 비교하여 세균들을 동정한 결과, 총 14종의 세균들이 확인되었다. 개인별로는 평균 2.5종의 배양 가능한 세균들을 손의 피부에 보유하는 것으로 확인되었다. 확인된 세균 중에서는 Staphylococcus 종들이 가장 널리 존재하고 있었으며, 다음으로는 Micrococcus luteus이었다. Staphylococcus 종들의 경우에는 그 분포에 있어서 성별에 따른 차이가 적었으나, Micrococcus luteus의 경우에는 남자보다 여자에게서 훨씬 더 많이 분리되는 경향을 보였다. 이러한 결과는 피부 질환에 대한 연구, 피부질환에 대한 치료제 개발, 피부에 사용하는 화장품개발 등의 분야에 도움이 될 것으로 사료된다.

• 대한약침학회지
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• 제4권2호
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• pp.35-47
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• 2001

Objectives : Through the literatures on the effets of Bufonis Venenum, we are finding out the clinical possibility and revealing the more effective to intractable diseases. Methods : We investigated the literatures of Oriental Medicine and experimental reports about Bufonis Venenum. Results : 1. Bufonis Venenum is made of bufonidae bufo bufo gargarizans cantor or bufo melanostictus schneider of white serum which secreted from parotid gland or dermato gland, and it is dried for using. 2. In oriental medicine, Bufonis Venenum has been mainly used on the tumors, cacanthrax and dermatic disease, and then it has been clinically used on infantile athrepsia, tetanus, sore throat, toothache, and so on. 3. The pharmacological effects of Bufonis Venenum are cardiotonic, respiration stimulation, depressor or vasopressor, topical anesthcsia, hallucination, striped muscle stimulation, antiasthmatic, antibacterial, antiinflammatory, anticancer, diuretic, immuno effects, etc. 4. Bufonis Venenum is largely divided in ether binding steroid compound, hydroxyl steroid compound, carboxyl or aldehyde steroid compound, indole compound, and adrenaline, cholesterole, etc. 5. Symptoms of Bufonis Venenum poisoning in digestive system are vommitig, abdominal pain, diarrhea, dehydration, in circulatory system are palpitation, shock, bradycardia, in nervous system are vertigo, somnolentia, muscle-tendon reflex weakness, and critical conditions to tissue necrosis and heart attack. 6. Ways to treat Bufonis Venenum poisoning include gastric irrigation with $0.2~0.5\%$ potassium permanganate fluid and atropine $0.5{\sim}1.0mg$ subcutaneous injection. From the chinese book of Bon Cho Gang Moke(本草綱目), if white serum of Bufonis Venenum enter the eyes, it happens the edema and pain. And then washed the eyes by juice of Lithospermi Radix(紫草) that the edema is removed. Conclusions and Discussion : The results from above literary studies show that prescriptions and Aqua-acupuncture of Bufonis Venenum could be clinically used to sedative, anticonvulsant, antibacterial, antiinflammatory, anticancer and topical ataralgesia. However it is expected that pharmacological and side effects of Bufonis Venenum are further studied.