• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.214-215
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• 2002

Generally uniform dose distribution is assumed to be formed in a target region when a conventional dose formation method using a broad proton beam, a fixed modulation technique, a bolus and an aperture is employed. However, actual situations differ. We usually find non-uniformity in the target region. This is due to the insertion of a range-compensating bolus before the patient. Since the range-compensating bolus has an irregular shape, the scattering in the bolus depends on the lateral position. Dose distribution is overlapping results of dose distribution of pencil-proton beams traversing different lateral positions of the bolus. The lateral extent of dose distribution of each pencil beam traversing the different position differs each other at the same depth in the target object. This is a cause of the non-uniformity of the dose distribution. Therefore the same lateral extent of dose distribution should be attained for different pencil beams at the same depth to obtain a uniform dose distribution. For that purpose, we propose here a bi-material bolus. The bi-material bolus consists of a low-Z material determining mainly the range loss and a high-Z material defining mainly the scattering in the bolus. After passing through the bi-material bolus, protons traversing different lateral positions will have different residual range yet with the same lateral spread at a certain depth. Using the optimized bi-material bolus, we can obtain a more uniform dose distribution in the target region as expected.

• 대한방사선치료학회지
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• 제14권1호
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• pp.175-186
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• 2002

The purpose of this study is directly measure and evaluate about absorbed dose change according to nominal energy and electron cone or medical accelerator on isodose curve, percentage depth dose, contaminated X-ray, inhomogeneous tissue, oblique surface and irradiation on intracavitary that electron beam with high energy distributed in tissue, and it settled standard data of hish energy electron beam treatment, and offer to exactly data for new dote distribution modeling study based on experimental resuls and theory. Electron beam with hish energy of $6{\sim}20$ MeV is used that generated from medical linear accelerator (Clinac 2100C/D, Varian) for the experiment, andwater phantom and Farmer chamber md Markus chamber und for absorbe d dose measurement of electron beam, and standard absorbed dose is calculated by standard measurements of International Atomic Energy Agency(IAEA) TRS 277. Dose analyzer (700i dose distribution analyzer, Wellhofer), film (X-OmatV, Kodak), external cone, intracavitary cone, cork, animal compact bone and air were used for don distribution measurement. As the results of absorbed dose ratio increased while irradiation field was increased, it appeared maximum at some irradiation field size and decreased though irradiation field size was more increased, and it decreased greatly while energy of electron beam was increased, and scattered dose on wall of electron cone was the cause. In percentage depth dose curve of electron beam, Effective depth dose(R80) for nominal energy of 6, 9, 12, 16 and 20 MeV are 1.85, 2.93, 4.07, 5.37 and 6.53 cm respectively, which seems to be one third of electron beam energy (MeV). Contaminated X-ray was generated from interaction between electron beam with high energy and material, and it was about $0.3{\sim}2.3\%$ of maximum dose and increased with increasing energy. Change of depth dose ratio of electron beam was compared with theory by Monte Carlo simulation, and calculation and measured value by Pencil beam model reciprocally, and percentage depth dose and measured value by Pencil beam were agreed almost, however, there were a little lack on build up area and error increased in pendulum and multi treatment since there was no contaminated X-ray part. Percentage depth dose calculated by Monte Carlo simulation appeared to be less from all part except maximum dose area from the curve. The change of percentage depth dose by inhomogeneous tissue, maximum range after penetration the 1 cm bone was moved 1 cm toward to surface then polystyrene phantom. In case of 1 cm and 2 cm cork, it was moved 0.5 cm and 1 cm toward to depth, respectively. In case of air, practical range was extended toward depth without energy loss. Irradiation on intracavitary is using straight and beveled type cones of 2.5, 3.0, 3.5 $cm{\phi}$, and maximum and effective $80\%$ dose depth increases while electron beam energy and size of electron cone increase. In case of contaminated X-ray, as the energy increase, straight type cones were more highly appeared then beveled type. The output factor of intracavitary small field electron cone was $15{\sim}86\%$ of standard external electron cone($15{\times}15cm^2$) and straight type was slightly higher then beveled type.

• 한국의학물리학회지:의학물리
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• 제2권2호
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• pp.141-148
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• 1991

수술중 방사선치료는 병소부위를 절제해 낸후 개복된 상태에서 정상조직을 조사면적 밖으로 밀어낸 후 국소재발의 위험이 가장 높은 부위에 전자선을 이용하여 한번에 다량의 방사선을 조사하는 방법이다. 수술중방사선치료를 시행하는 병원마다 콘의 모양, 시행방법, 조사선량등이 모두 달라 사용하는 콘의 선량분포 및 치료면적의 범위, 누설선량등은 치료효과의 중요한 지표가 된다. 저자들은 본 교실에서 지금까지 제작한 여러가지 수술중 방사선치료 콘의 선량분포 특성을 비교 검토하였다.

• 방사선산업학회지
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• 제12권4호
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• pp.297-302
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• 2018

The wedge filter has two movements, fixed and dynamic. In this study, the depth dose distribution was analyzed to determine the stability of the dose distribution and dose volume histograms obtained by evaluating the usability of the critical normal tissue dose around the tumor dose. The depth dose was analyzed from the dose distribution from a Linac (6 MV and 10 MV irradiation field of energy $20{\times}20cm^2$, wedge filter with a SSD of 100 cm and $15^{\circ}$, $30^{\circ}$, $45^{\circ}$ Y1-in (Left -7 cm), Y2-out(Right +7 cm). To analyze the fluctuations of the depth dose, a fixed wedge and dynamic wedge toe portion was examined according to the energy and angle because the size of the fluctuations was included in the error bound and did not show significant differences. The neck, breast, and pelvic dosimetry in tumor tissue are measured more commonly with a dynamic wedge than a fixed wedge presumably due to the error range. On the other hand, dosimetry of the surrounding normal tissue is more common using a fixed wedge than with a dynamic wedge.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.244-247
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• 2002

We examined a possibility to use inorganic plastic scintillator, which has the effective atomic number close to that of human soft tissue, for the measurement of dose distributions in a shorter time period. The method was to irradiate a block of plastic scintillator as a phantom, and to measure the distribution of the scintillation light by a wave length analyzer through a thread of plastic optical fiber. By irradiating the diagnostic x-ray, we observed the emission spectrum of the scintillation light from the scintillator. It showed a peak at around 420nm with a full width of 140 nm. The emission spectrum was integrated to determine the total number of photons. The dependences of the amount of photons on the irradiated dose were measured. The results of the experiment show that the amount of emission light is in proportional to the irradiated dose. From this fact, we conclude that the present method can be used for the measurement of the depth dose distribution of the diagnostic x-rays.

• Nuclear Engineering and Technology
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• 제7권4호
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• pp.285-293
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• 1975

30cm 직경 포리에티렌 구체내의 길이에 따른 선량분포중 최대흡수선량인 흡수선량지수를 주어진 감마방사선장내에서 열형광선량계를 이용하여 결정하였다. 열형광선량계내의 흡수선량과 주위 눈질내의 흡수선량간의 환산은 Burlin의 general cavity theory에 의거하였다. $^{60}$Co과 $^{137}$Cs에 의한 방사선장에서 구체내 최대흡수선량은 구체표면으로 부터 각각 0.5cm 및 0.3cm에 나타났으며 이 결과는 이론적으로 예상한 분포특성과 아주 근사하였다.

• Radiation Oncology Journal
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• 제1권1호
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• pp.29-36
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• 1983

The treatment of tumors along curved surfaces with stationary electron beams using cone collimation may lead to non-uniform dose distributions due to a varying air gap between the cone surface and patient. For large tumors, more than one port may have to be used in irradiation of the chest wall, often leading to regions of high or low dose at the junction of the adjacent ports. Electron-beam arc therapy may elimination many of these fixed port problems. When treating breast tumors with electrons, the energy of the internal mammary port is usually higher than that of the chest wall port. Bolus is used to increase the skin dose or limit the range of the electrons. We invertiaged the effect of various arc beam parameters in the isodose distributions, and combined into a single arc port for adjacent fixed ports of different electron beam eneries. The higher fixed port energy would be used as the arc beam energy while the beam penetration in the lower energy region would be controlled by a proper thickness of bolus. We obtained the results of following: 1. It is more uniform dose distribution of electron to use rotation than stationary irradiation. 2. Increasing isocenter depth on arc irradiation, increased depth of maximum dose, reduction in surface dose and an increasing penetration of the linear portion of the curve. 3. The deeper penetration of the depth dose curve and higher X-ray background for the smaller field sized. 4. If the isocenter depth increase, the field effect is small. 5. The decreasing arc beam penetration with decreasing isocenter depth and the isocenter depth effect appears at a greater depth as the energy increases. 6. The addition of bolus produces a shift in the penetration that is the same for all depths leaving the shape of the curves unchanged. 7. Lead strips 5 mm thick were placed at both ends of the arc to produce a rapid dose drop-off.

• 한국의학물리학회지:의학물리
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• 제28권2호
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• pp.49-53
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• 2017

The energy distribution was calculated for an electron beam from an electron linear accelerator developed for medical applications using computational methods. The depth dose data for monoenergetic electrons from 0.1 MeV to 8.0 MeV were calculated by the DOSXYZ/nrc code. The calculated data were used to generate the energy distribution from the measured depth dose data by numerical iterations. The measured data in a previous work and an in-house computer program were used for the generation of energy distribution. As results, the mean energy and most probable energy of the energy distribution were 5.7 MeV and 6.2 MeV, respectively. These two values agreed with those determined by the IAEA dosimetry protocol using the measured depth dose.

• 한국의학물리학회지:의학물리
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• 제10권2호
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• pp.83-88
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• 1999

목적 : 금속박막과 고체 팬텀이 선량 분포와 선량 측정에 미치는 영향을 연구하기 위하여 TLD 실험을 행하였다. 본 연구의 목적은 주어진 고체 팬텀 환경 내에서 TLD 기판 위에 놓인 금속박막의 build-up 효과와 깊이선량 분포를 알아보고자 하였다. 대상 및 방법 : 측정은 TLD 기판과 같은 면적 (3.2 $\times$ 3.2 $\textrm{mm}^2$)의 금속박막을 LiF TLD-100 위에 얹어서 행하였다. 여러 종류 (주석, 구리, 금) 의 다양한 두께 (0.1, 0.15, 0.2, 0.3 mm)를 가진 금속박막 중에 한 개를 TLD 기판 위에는 얹어서 각 각의 흡수선량을 측정하였다. 금속박막을 얹은 TLD 기판을 사용하여 고체 팬텀에서의 표면홉수선량과 최대 build-up 영역에서 흡수선량을 측정하였다. 결과 : 금속박막을 이용한 TLD 기판의 경우 표면흡수선량이 증가하였고, 물에 대한 금속의 등가 두께에 따른 표면흡수선량 곡선에는 build-up 이 뚜렷이 관측되었다. 최대 build-up 영역에서 관측한 흡수선량 측정값은 금속박막을 없지 않은 TLD의 경우보다 약 8% 에서 13% 정도의 보다 작은 값을 나타내었다. 결론 : TLD 선량 측정 시 금속 박막 법은 깊이에 따른 흡수선량 뿐 만 아니라 피부 표면으로부터 약 4.2mm 깊이까지의 홉수선량의 build-up 에 관련 정보를 의료진에 제공할 수 있으며, 금속박막을 얹은 TLD에 관한 실험 결과는 피부 특정 영역에서의 bolus 의 결정에 도움이 될 것으로 사료됨.

• 한국의학물리학회지:의학물리
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• 제31권4호
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• pp.135-144
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• 2020

Purpose: Gafchromic films for proton dosimetry are dependent on linear energy transfers (LETs), resulting in dose underestimation for high LETs. Despite efforts to resolve this problem for single-energy beams, there remains a need to do so for multi-energy beams. Here, a bimolecular reaction model was applied to correct the under-response of spread-out Bragg peaks (SOBPs). Methods: For depth-dose measurements, a Gafchromic EBT3 film was positioned in water perpendicular to the ground. The gantry was rotated at 15° to avoid disturbances in the beam path. A set of films was exposed to a uniformly scanned 112-MeV pristine proton beam with six different dose intensities, ranging from 0.373 to 4.865 Gy, at a 2-cm depth. Another set of films was irradiated with SOBPs with maximum energies of 110, 150, and 190 MeV having modulation widths of 5.39, 4.27, and 5.34 cm, respectively. The correction function was obtained using 150.8-MeV SOBP data. The LET of the SOBP was then analytically calculated. Finally, the model was validated for a uniform cubic dose distribution and compared with multilayered ionization chamber data. Results: The dose error in the plateau region was within 4% when normalized with the maximum dose. The discrepancy of the range was <1 mm for all measured energies. The highest errors occurred at 70 MeV owing to the steep gradient with the narrowest Bragg peak. Conclusions: With bimolecular model-based correction, an EBT3 film can be used to accurately verify the depth dose of scanned proton beams and could potentially be used to evaluate the depth-dose distribution for patient plans.