• Industrial Engineering and Management Systems
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• 제2권1호
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• pp.28-34
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• 2003

The fundamental design issues that arise in the pickup and delivery system planning are optimizing the system with minimum cost and maximum throughput and service level. This study is concerned with the development of pickup and delivery system with customer responsive service level, DCM(Demand Chain Management). The distribution process and service map are consisted of manufacturing, warehousing, and pickup and delivery. First we formulated the vehicle pickup and delivery problem using GIS-VRP method so as to satisfy the customer service requests. Second, we developed a GUI-type computer program using AVL, automated vehicle location system. The computational results show that the proposed method is very effective on a set of test problems.

• 산업경영시스템학회지
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• 제23권58호
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• pp.59-69
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• 2000

Development of digital information and internet technology causes the changes of technology environments and companies, and the variety of customer needs has been dynamically changed in terms of integrating information system with customer satisfaction. Moreover a new logistics concept is needed through the sharing information between suppliers and consumers, which maximizes the level of customers service and its flexibility by changing functional-oriented to process-oriented. In other words, Supply Chain Management (SCM) is now considered as a key aspect of business, which controls the flows of information, funds, and goods in the supply chain. Rationalization of transport-delivery system will be one of the most important issues on logistics management to the domestic companies. The companies need the effective delivery system. Especially in the case of delivery system from distribution centers to customers or vendors, it might take a long time to control the delivery system manually because it would be hard to apply the automatic vehicle routing algorithm effectively considering all the practical constraints. Thus this study develops a heuristic algorithm of automatic vehicle delivery support system in terms of grouping by short ranges of vehicle movement utilizing postal coordinates, which satisfies a variety of realistic constraints and reduces controlling time of manual operations. In addition, the performance of the algorithm developed in this study is evaluated through the case study.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2002년도 가을 학술발표논문집 Vol.29 No.2 (3)
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• pp.76-78
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• 2002

Multicasting over mobile IP network becomes more important with the increasing needs of supporting multimedia services in mobile network. The IETF has suggested two approaches which are remote subscription and bidirectional tunneling for supporting mobility management in multicasting over mobile IP. But these protocols have problems - the frequent reconstruction of multicast delivery tree, packet less during handoff, convergence problem, and so on. In this paper, we propose to use preconfiguration of multicast delivery tree when mobile host enters the foreign network. It will decrease the frequency of multicast delivery tree reconstruction, and reduce the packet loss during handoff, Also the multicast delivery tree maintained by Keep Alive messages makes the signaling overload of networks diminished.

• 한국주거학회논문집
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• 제27권4호
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• pp.33-46
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• 2016

In era of lowbirth, aging population, low growth and social polarization, the effective welfare delivery systems are taking on added significance than past years. Public housing welfare resources, such as public rental housing, housing voucher, affordable housing loan, are more diversified and expanded. These programs could work effectively by the comprehensive interlink and community based delivery system. From the standpoint of recipients, how effectively the substantial benefits of welfare resources being delivered to each individual is more important than how much welfare resources being produced totally. This study aimed to explore the reform of public housing welfare delivery system. For this purpose, diagnosed the current states and key issues related to public delivery system, and analyzed what kinds of housing welfare services should be strengthened, and finally suggested the collaboration among the public sectors (local government, LH, HUG, HF etc.) and the partnership with non-profit organizations. Main research implications are as follows. The main housing welfare services which could be categorized as the housing welfare center's role are advice & information offering, several public resources interlink and accessibility improvement, community based network construction, etc. And the most important key for successful delivery system reorganization is the collaborative operation of the public sectors and local government, non-profit organizations.

• 한국보건간호학회지
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• 제17권1호
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• pp.5-16
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• 2003

This policy alternatives for establishment of rehabilitation health care delivery system for the disabled in the community were developed based on the data of current health status and situations of health care management for disabled persons in Korea. This research was conducted with secondary data analysis for identifying health status and current situations of managing health of disabled persons, and discussed current issues for establishing rehabilitation health care delivery systems in the community. Observing the health status and current situations of managing health of disabled persons, scope and target population of disabled person extended. so prevalence rates increased. and the severity of disability intensified and specified. The summary of issues of health management for disabled persons included; 1) absence of comprehensive and systematic policy in rehabilitation health care systems. 2) absence of consumer based rehabilitation health care facilities and delivery systems that are considered as the characteristics of disabled persons 3) fixed form of projects based on the provider and lack of variety in the programs. Hereafter. to overcome these problems. policy alternatives should 1) establish a comprehensive rehabilitation health care policy for disabled persons. 2) establish comprehensive and specific community based rehabilitation health care delivery systems that can promote preventing disability. providing medical care for disabled persons, establishing rehabilitation management for disabled persons and health care when returning to society. 3) provide training and secure manpower for rehabilitation, but the training case managers who will take the roles as an expert rehabilitation nurse mediators for multidisciplinary team work are needed immediately. and 4) include efficient connection and provision of independent services for welfare rehabilitation service and health care. Conclusively. a community based rehabilitation health care delivery system should be comprehensive policy vision of the government on rehabilitation health care delivery System rehabilitation service has to be constructed systematically under suitable facilities con consumer characteristics and rehabilitation health care policy. By doing this, consumer comprehensive community rehabilitation health care delivery system could be constructed disabled person.

• 한국축산식품학회지
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• 제43권2호
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• pp.220-231
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• 2023

Although omega-3 fatty acids including docosahexaenoic acid (DHA) contain various health-promoting effects, their poor aqueous solubility and stability make them difficult to be induced in dairy foods. The aims of this research were to manufacture casein derivative-based delivery system using acid-induced gelation method with glucono-σ-lactone and to investigate the effects of production variables, such as pH and charged amount of linoleic acid, on the physicochemical properties of delivery systems and oxidative stability of DHA during storage in model milk. Covalent modification with linoleic acid resulted in the production of casein derivatives with varying degrees of modification. As pH was reduced from 5.0 to 4.8 and the charged amount of linoleic acid was increased from 0% to 30%, an increase in particle size of casein derivative-based delivery systems was observed. The encapsulation efficiency of DHA was increased with decreased pH and increased charged amount of linoleic acid. The use of delivery system for DHA resulted in a decrease in the development of primary and secondary oxidation products. An increase in the degree of modification of casein derivatives with linoleic acid resulted in a decrease in the formation of primary and secondary oxidation products than of free DHA indicating that delivery systems could enhance the oxidative stability of DHA during storage in model milk. In conclusions, casein derivatives can be an effective delivery system for DHA and charged amount of linoleic acid played a key role determining the physicochemical characteristics of delivery system and oxidative stability of DHA.

• Korean Chemical Engineering Research
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• 제58권3호
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• pp.450-457
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• 2020

선행된 연구에서 Yo-Pro-1의 전달 효율의 경향과 CFP 유전자의 발현 효율의 경향이 큰 차이를 보였지만 이 문제에 대한 원인을 제시할 수 없었다. 따라서 본 연구에서는 형광 염료를 이용하여 DNA에 표지 후 전달 효율을 정량화함으로써 이 문제에 대한 원인을 찾고자 한다. 표지를 위한 형광 염료로 Yo-Pro-1을 사용하였으며, Yo-Pro-1과 표지 된 DNA의 전달 효율을 비교하였다. 전압 조건에 따른 전달효율 비교에서는 Yo-Pro-1과 Yo-Pro-1으로 표지 된 DNA의 전달 효율 모두 96 V에서 전달 효율이 최대가 되었으며 전압이 더 증가하면 전달 효율이 오히려 감소하는 경향을 보였다. 전압 인가 횟수 조건에 따른 전달 효율 비교에서는 Yo-Pro-1과 Yo-Pro-1으로 표지 된 DNA의 두 전달 물질 모두 8회의 전압 인가 횟수에서 전달 효율이 최대가 되었으며 전압 인가 횟수가 더 증가하면 전달 효율이 감소하는 경향을 보였다. 두 결과를 통해 디지털 전기천공시스템에서 Yo-Pro-1을 사용한 전달 효율 측정이 DNA의 전달 효율을 잘 대변하는 것을 확인하였다. 또한, 본 연구의 결과를 통해 선행된 연구에서 보인 Yo-Pro-1의 전달 효율의 경향과 CFP 유전자의 발현 효율의 경향 차이는 전달 물질의 전달 효율 차이에서 기인한 결과가 아닌 전달 된 유전 물질의 발현 과정에서의 문제로 인한 결과임을 추론해 볼 수 있었다.

• Archives of Pharmacal Research
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• 제25권3호
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• pp.229-239
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• 2002

Recent progress in understanding the molecular basis of cancer brought out new materials such as oligonucleotides, genes, peptides and proteins as a source of new anticancer agents. Due to their macromolecular properties, however, new strategies of delivery for them are required to achieve their full therapeutic efficacy in clinical setting. Development of improved dosage forms of currently marketed anticancer drugs can also enhance their therapeutic values. Currently developed delivery systems for anticancer agents include colloidal systems (liposomes, emulsions, nanoparticles and micelles), polymer implants and polymer conjugates. These delivery systems have been able to provide enhanced therapeutic activity and reduced toxicity of anticancer agents mainly by altering their pharmacokinetics and biodistribution. Furthermore, the identification of cell-specific receptor/antigens on cancer cells have brought the development of ligand- or antibody-bearing delivery systems which can be targeted to cancer cells by specific binding to receptors or antigens. They have exhibited specific and selective delivery of anticancer agents to cancer. As a consequence of extensive research, clinical development of anticancer agents utilizing various delivery systems is undergoing worldwide. New technologies and multidisciplinary expertise to develop advanced drug delivery systems, applicable to a wide range of anticancer agents, may eventually lead to an effective cancer therapy in the future.

• 한국도서관정보학회지
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• 제16권
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• pp.191-220
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• 1989

This study is an attempt to furnish some helpful data for the design and implementation of the electronic document delivery system based on the analysis of it's cases. To begin with, the concepts and basic models of electronic document delivery system(Fig. 1) were overviewed in the second chapter, on the basis of which the concrete cases were introduced in the third chapter ; ADONIS Project, ARTEMIS Project, HERMES Project, APOLLO Project, UNIVERSE Project, DOCDEL Project, and etc. In the future rapidly developed the technology of electronic communication, there are many possibilities of the evolution of electronic document delivery system.

• 한국주거학회논문집
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• 제20권1호
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• pp.123-132
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• 2009

The purpose of this study was to establish the housing welfare delivery system in Incheon. Documentary research and content analysis methods and survey were used in this study. Data drawn from internet homepage of each community center, gu-office and city hall in Incheon. The major results of this study are as follows. 1) Related works of housing welfare are housing welfare facility management, self helf center, support service of housing life, residential environment management 2) Housing welfare delivery system consists of city, gu-office, community center order. There are many problems that the lack of experts and department of housing welfare and inconsistent works. 3) There should be optimize the related works of housing welfare in order to increase of efficiency of works and to prevent overload to public servant. 4) Housing welfare delivery system needs to co-work through collaborative network in order to realize welfare society. And each main groups have to establish their horizontal relationships.