• 대한의용생체공학회:의공학회지
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• 제28권6호
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• pp.791-797
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• 2007

This paper proposes a semiautomatic vertebra segmentation method that overcomes limitations of both manual segmentation requiring tedious user interactions and fully automatic segmentation that is sensitive to initial conditions. The proposed method extracts fence surfaces between vertebrae, and segments a vertebra using fence-limited region growing. A fence surface is generated by a deformable model utilizing valley information in a valley emphasized Gaussian image. Fence-limited region growing segments a vertebra using gray value homogeneity and fence surfaces acting as barriers. The proposed method has been applied to ten patient data sets, and produced promising results accurately and efficiently with minimal user interaction.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2007년도 춘계학술대회A
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• pp.780-785
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• 2007

Accurate and fast haptic simulations of deformable objects are desired in many applications such as medical virtual reality. In haptic interactions with a coarse model, the number of nodes near the haptic interaction region is too few to generate detailed deformation. Thus, local refinement techniques need to be developed. Many approaches have employed purely geometric subdivision schemes, but they are not proper in describing the deformation behavior of deformable objects. This paper presents a continuum mechanics-based finite element adaptive method to perform haptic interaction with a deformable object. This method superimposes a local fine mesh upon a global coarse model, which consists of the entire deformable object. The local mesh and the global mesh are coupled by the s-version finite element method (s-FEM), which is generally used to enhance accurate solutions near the target points even more. The s-FEM can demonstrate a reliable deformation to users in real-time.

• 전기학회논문지
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• 제59권8호
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• pp.1477-1481
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• 2010

In this paper, we propose the classification and tracking method of the hand region using deformable template and condensation. To do this, first, we extract the hand region by using the fuzzy color filter and HCbCr color model. Second, we extract the edge of hand by applying the Canny edge algorithm. Third, we find the first template by calculating the conditional probability between the extracted edge and the model edge. If the accurate template of the first object is decided, the condensation algorithm tries to track it. Finally, we demonstrate the effectiveness and feasibility of the proposed method through some experiments.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 학술대회 논문집 정보 및 제어부문
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• pp.3-5
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• 2005

Vessel boundary detection and modeling is a difficult but a necessary task in analyzing the mechanics of inflammation and the structure of the microvasculature. In this paper we present a method of analyzing the structure by means of an active contour model(using GVF Snake) for vessel boundary detection and 3D reconstruction. For this purpose we used a virtual vessel model and produced a phantom model. From these phantom images we obtained the contours of the vessel by GVF Snake and then reconstructed a 3D structure by using the coordinates of snakes.

• 한국정보과학회논문지:시스템및이론
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• 제29권11호
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• pp.589-600
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• 2002

변형 모델은 볼륨영상으로부터 관심 대상 객체의 3차원적 경계면 구조 추출을 위해 효과적인 접근 방법을 제공한다. 그러나, 기존 변형 모델은 초기 조건에 민감하고, 심한 함몰 및 돌출 부위를 가지는 복잡한 경계면을 잘 표현하지 못하면, 모델 내 구성 요소들 간에 자기교차를 일으킬 수 있는 세가지 주요 제한점이 있다. 본 논문에서는 기존 변형 모델이 갖는 이러한 제한점을 개선함으로써 복잡한 기하학적 표면 형태를 가지는 객체의 경계면 추출에 효과적인 변형 모델을 제안한다. 첫째, 제안 변형 모델은 다해상도 볼륨영상 피라미드를 기반으로 모델구성 요소들을 계층적으로 리샘플링한다. 이 접근은 객체의 경계면을 멀티스케일 방식으로 추출함으로써 초기화에의 의존성을 극복할 뿐 아니라, 모델 구성 요소들의 크기를 복셀 크기에 따라 항상 균일하게 유지함으로써 모델이 영상의 복잡한 특성 정보에 따라 유동적으로 변형될 수 있게 한다. 둘째, 제안 변형 모델은 기존 모델에서 가지는 내력과 외력 외에 자기교차방지력을 포함한다. 자기교차방지력은 제한 거리 이내로 근접한 비인접 모델구성 요소들간에 척력을 적용함으로써 자기교차를 사전에 방지한 수 있게 한다. 본 논문에서는 다양한 합성 볼륨영상 및 뇌 MR 볼륨영상에 대한 실험을 통해서 제안 모델이 초기화 위치에 의존하지 않고 자기교차 없이 복잡한 함몰 및 돌출 경계면 구조를 성공적으로 추출한 결과를 보인다.

• Journal of Pharmaceutical Investigation
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• 제34권6호
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• pp.483-489
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• 2004

Fexofenadine HCl is non-sedating histamine H1 receptor antagonist that can be used for the treatment of seasonal allergic rhinitis. The objective of this study was to investigate whether the carriers of deformable liposomes can enhance the transepithelial permeability of fexofenadine HCl across the in vitro ALI human nasal monolayer model. Characterization of this model was achieved by bioelectric measurements and morphological studies. The passage 2 and 3 of cell monolayers exhibited the TEER value of $2852\;{\pm}\;482\;ohm\;{\times}\;cm^2$ on 11 days of seeding and maintained high TEER value for 5 days. The deformable liposome of fexofenadine HCl was prepared with phosphatidylcholine (PC) and cholic acid using extruder method. The mean particle size was about 200 nm and the maximum entrapment efficiency of 33.0% was obtained in the formulation of 1% PC and $100\;{\mu}g/ml$ fexofenadine HCl. The toxicity of the deformable liposome to human nasal monolayers was evaluated by MTT assay and TEER value change. MTT assay showed that it has no toxic effect on the nasal epithelial cells in 2-hour incubation when the PC concentration was below 1%. However, deformable liposome could not enhance the transepithelial permeability $(P_{app})$ and cellular uptake of fexofenadine HCl. In conclusion, the in vitro model could be used in nasal drug transport studies and evaluation of transepithelial permeability of formulations.

• Advances in concrete construction
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• 제15권5호
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• pp.349-358
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• 2023

Aim of this work is investigating effect of thickness-stretching formulation on the quasi three-dimensional analysis of micro plate based on a thickness-stretched and shear deformable model through principle of virtual work and micro-scale dependent constitutive relations. Governing differential equations are derived in terms of five unknown functions and the analytical solution is derived using Navier's technique. To explore effect of thickness stretching model on the static results, a comparison between the results with and without thickness stretching effect is presented.

• 한국공간구조학회논문집
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• 제5권3호
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• pp.65-74
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• 2005

본 연구에서는 사각형 모듈의 인발성형된 복합재료 바닥판의 휨 거동에 대한 해석 모델을 개발하였다. FRP 바닥판의 해석 모델은 FSDT 평판 이론을 기반으로 임의 적층각을 지닌 FRP 바닥판의 처짐을 예측할 수 있었다. 수치적 예제에서는 네 변이 단순 지지된 등분포 하중을 받는 사각형 모듈의 FRP 바닥판을 2차원 평판 유한 요소해석을 적용하여 수행하였고, 해석 결과에 대해서는 바닥판 길이-높이의 비와 화이버 각도의 변화에 따른 효과에 대해 역점을 두고 다루었다. 연구 결과, 본 연구에서 제안한 해석 모델이 FRP 바닥판의 휨 거동을 해석하고 예측하는데 효과적이고 정확하다는 것이 입증되었다. 또한, FRP 바닥판의 높이가 높아질수록 plate 해석 이론에 있어서 일차전단변형이론(First order Shear Deformable laminated plate Theory : FSDT)이 아닌 고차전단변형(Higher order Shear Deformable plate Theory : HSDT)의 필요성에 대해 언급하였다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1996년도 한국자동제어학술회의논문집(국내학술편); 포항공과대학교, 포항; 24-26 Oct. 1996
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• pp.221-224
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• 1996

Since impact phenomenon is highly nonlinear, the analysis and control of the contact motion has been a challenging subject. Various researches have been carried out mostly for the contact of a rigid robotic manipulator with a stiff and elastic environment. This paper is motivated by a new contact task: the in-circuit test of a printed circuit board. In this process, high speed contact occurs between a rigid probing manipulator and a plastically deformable work environment. A new dynamic model of the impact controlled probing task has been proposed, considering contact with the plastically deformable object. Approaching velocity conditions to avoid an excess of the allowable penetration depth and control the generated impact force properly are derived from the proposed model. The results of the simulation studies are made for various probing conditions and show the validity of the proposed model.

• 대한기계학회논문집A
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• 제32권4호
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• pp.362-370
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• 2008

In this paper, we propose a 2D-FE model in single impact with combined physical factors to obtain a unique residual stress by shot peening. Applied physical parameters consist of elastic-plastic deformation of shot ball, material damping coefficients, strain rate, dynamic friction coefficients. As a kinematical parameter, there is impact velocity. Single impact FE model consists of 2D axisymmetric elements. The FE model with combined factors showed converged and unique distributions of surface stress, maximum compressive residual stress and deformation depth. Further, in contrast to the FE models with rigid shot and elastic deformable shot, FE model with plastic deformable shot produces residual stresses very close to experimental solutions by X-ray diffraction. We therefore validated the 2D FE model with combined peening factors and plastic deformable shot. This FE model will be a base of the 3D FE model for residual stresses by multi-impact shot peening.