• 제어로봇시스템학회논문지
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• 제17권8호
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• pp.753-759
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• 2011

The HIV (Human Immunodeficiency Virus) causes AIDS (Acquired Immune Deficiency Syndrome). The process of infection and mutation by HIV can be described by a 3rd order state equation. For this HIV model that includes the dynamics of the mutant virus, we present a parameter estimation scheme using two state variables sporadically measured, out of the three, by employing a genetic algorithm. It is assumed that these non-uniformly sampled measurements are subject to random noises. The effectiveness of the proposed parameter estimation is demonstrated by simulations. In addition, the estimated parameters are used to analyze the equilibrium points of the HIV model, and the results are shown to be consistent with those previously obtained.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2009년도 정보 및 제어 심포지움 논문집
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• pp.135-137
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• 2009

Mathematical models for describing the Human Immunodeficiency Virus(HIV) infection can be devised to better understand how the HIV causes Acquired Immune Deficiency Syndrome(AIDS). The HIV models can then be used to find clues to curing AIDS from a control theoretical point of view. Some models take Cytotoxic T Lymphocytes(CTL) response to HIV infection into account, and others consider mutants against the drugs. However, to the best of our knowledge, there has been no model developed, which describes CTL response and mutant HIV together. Hence we propose a unified model to consider both of these. On the basis of the resulting model, we also present a Model Predictive Control(MPC) scheme to find an optimal treatment strategy. The optimization is performed under the assumption that the Structured Treatment Interruption(STI) policy is employed.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제8권2호
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• pp.269-274
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• 2005

저자들은 평소 건강하게 지내던 소아에서 발생한 식도 칸디다증 1예를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.

• 대한한의학방제학회지
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• 제11권1호
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• pp.205-216
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• 2003

A general review is made on Insamyangwitang(人蔘養胃湯). Following conclusions are drawn from the clinical cases of Insamyangwitang in Hyungsang medicine. 1. Insamyangwitang is composed of four different prescriptions of Huisaentang, Sakoonjatang, Eajintang and Pyungwisan. Huisaentang is usually prescribed for the intestinal convulsion. Sakoonjatang for the deficiency of Ki. Eajintang for retention of phlegm. 2. Insamyangwitang is effective in strengthening the spleen, drying the dampness, warning the middle-warmer to stop vomiting, regulating the flow of Ki, and eliminating phlegm. 3. Insamyangwitang is applicable to malaria caused by cold, intestinal convulsion, abdominal mass, edema, tympanites, Yin syndrome of exogenous febrile disease, distension, lack of appetite, stomachache, and diarrhea. 4. Persons with the following characteristic in Hyungsang are more susceptible to Insamyangwitang : Jung type, Hyul type, fish type, Taium meridian type, white fat damp constitution, person with big mouth, and woman rather than man.

• 대한한의학회지
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• 제22권3호
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• pp.169-178
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• 2001

After initial recovery from acute carbon monoxide (CO) intoxication, some patients occasionally undergo severe neuropsychiatric deterioration, which is called postanoxic delayed encephalopathy (sequelae). This is the clinical report about one patient, a 73-year-old man, diagnosed with delayed encephalopathy after acute CO intoxication. The symptoms of the patient were mental dysfunction including memory impairment and disorientation, abnormal behavior, incontinence and mutism. He had completely recovered after an aonxic episode, but the neurological symptoms that developed were preceded by an interval of apparent normality (the 'lucid interval'). We characterized him as suffering deficiency syndrome of the heart and prescribed for him Bokreongbosim-tang and Guipi-tang, and thereafter his symptoms were remarkably improved. For the evaluation of clinical improvement, we use the Modified Barthel Index (MBI), Canadian Neurologic Scale (CNS), and the Korean version of the Mini-Mental State Examination (K-MMSE)

• 대한한의학원전학회지
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• 제19권2호통권33호
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• pp.266-293
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• 2006

Accumulation of pathogens in chest refers to a syndrome of fullness, stuffiness and pain in the chest, diaphragm, epigastrium and abdomen, which is ascribable to accumulation of pathogenic heat with stagnancy of fluid or phlegm in the chest. Retching refers to vomiting with sound but without any vomitus. It is usually ascribable to adverse flow of ki due to deficiency of stomach, or by pathogenic heat or cold, and failure in descending of the stomach-ki. It may also be found in Soyang disease. Bloody purulent stool refers to passing stool with blood and pus. It is formed mainly due to invasion of the stomach and the intestines by epidemic pathogenic summer-heat, steaming of stagnateed damp-heat fighting against ki and blood, or improper diet, obstruction of bu-ki stagnation of blood and ki.

• 대한한방내과학회지
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• 제25권4호
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• pp.186-191
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• 2004

The following case illustrates the efficacy of Yanghyulgupung-tang and accupuncture therapy in the treatment of Dupung caused by cerebral infarction. The chief symptoms of the Dupung are dysesthesia in face, dizziness, and a disorder in the sense of smell (such as oversensibility or insensibility to the smell of food). Yanghyulgupung-tang is the medicine which treats women's Dupung with the deficiency syndrome of Liver. After medication to patient, the symptoms of Dupung decreases rapidily within the first week. This result supports the clinical efficacy of Yanghyulgupung-tang for the treatment of Dupung caused by cerebral infarction.

• 한국동물위생학회지
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• 제37권1호
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• pp.59-65
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• 2014

Equine herpesvirus myeloencephalopathy, out of symptoms by equine herpesvirus type 1 (EHV-1) infection, can cause devastating losses on individual farms. Although myeloencephalopathy syndromes of horses in Korea have been recognized for a couple of years in horse populations, there is little study regarding the occurrence of EHV-1 infections. The present study was performed to detect the viral infection of horses with neurological syndrome using real-time PCR. Fifteen horses (27.3%) out of 55 horses with neurological deficiency were positive for EHV-1 viral antigen. Among these 7 horses, 4 horses were detected genotype of A2254/N752 and 3 horses G2254/D752 strain, respectively.

• 한방비만학회지
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• 제6권1호
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• pp.11-26
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• 2006

Hair tissue mineral analysis is widely accepted for assessing essential and toxic elements which can give information about disease, metabolic disorder, nutritional imbalance, drug abuse, environmental exposure and so on. In Oriental Medicine, hair have been used as a diagnostic method which reflects the physiological and pathological status of body, especially kidney system(腎臟) and blood(血) like the quotations from Donguibogam(東醫寶鑑), 'hair belongs to kidney system(髮屬腎)' and 'hair is the remainder of blood(髮者血之餘)' Therefore we have suggested that HTMA have possibility to be utilized for screening and treatment for obesity, growth disorder, general deficiency syndrome(諸虛證), etc. in Oriental Medicine.

• 대한소아치과학회지
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• 제35권3호
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• pp.532-538
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• 2008

Lesch-Nyhan 증후군은 드물게 나타나는 X 염색체 열성 유전 질환으로 purine의 대사 장애를 보이는 질환이다. Purine의 대사 장애는 대사에 관여하는 효소인 hypoxanthine guanine phosphoribosyl transferase의 결손 또는 활성 감소로 인하여 나타나며, 요산의 과다 생산에 의한 요산과다혈증, 요산과다뇨증 등의 신장계 증상과 정신지체, 무도증 등의 신경학적 장애를 보이고, 구강이나 손가락에 대한 자해를 나타낸다. 이 중 자해 행위는 입술과 혀, 손가락을 깨무는 경우가 흔하고, 심하면 혀와 손가락이 완전히 절단될 수도 있다. 이 경우 자해로 인한 통증뿐 아니라, 연조직 결손으로 인한 심미적인 문제와 상처 부위로의 2차 감염이 발생할 수 있다. 이러한 Lesch-Nyhan 증후군 환자에서 자해를 막기 위해 여러 방법이 사용되고 있는데, 이 중 치과적으로 접근하는 방법으로는 마우스 가드나 lip bumper 등의 장치를 이용하는 방법과 해당 치아들을 모두 발거하는 방법, 악교정 수술을 통해 개방 교합을 형성해 주는 방법 등이 있다. 본 증례는 13세 9개월의 Lesch-Nyhan 증후군 환아로서 자해에 의해 혀에 심각한 외상을 가한 경우로 마우스 가드를 이용한 보존적인 방법을 사용하였으나 계속적으로 혀에 외상을 가해 하악 전치 뿐 아니라 구치까지 발거하여 치료하였다.