• Title/Summary/Keyword: de-correlation

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Analysis of electroencephalogram-derived indexes for anesthetic depth monitoring in pediatric patients with intellectual disability undergoing dental surgery

  • Silva, Aura;Amorim, Pedro;Felix, Luiza;Abelha, Fernando;Mourao, Joana
    • Journal of Dental Anesthesia and Pain Medicine
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    • 제18권4호
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    • pp.235-244
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    • 2018
  • Background: Patients with intellectual disability (ID) often require general anesthesia during oral procedures. Anesthetic depth monitoring in these patients can be difficult due to their already altered mental state prior to anesthesia. In this study, the utility of electroencephalographic indexes to reflect anesthetic depth was evaluated in pediatric patients with ID. Methods: Seventeen patients (mean age, $9.6{\pm}2.9years$) scheduled for dental procedures were enrolled in this study. After anesthesia induction with propofol or sevoflurane, a bilateral sensor was placed on the patient's forehead and the bispectral index (BIS) was recorded. Anesthesia was maintained with sevoflurane, which was adjusted according to the clinical signs by an anesthesiologist blinded to the BIS value. The index performance was accessed by correlation (with the end-tidal sevoflurane [EtSevo] concentration) and prediction probability (with a clinical scale of anesthesia). The asymmetry of the electroencephalogram between the left and right sides was also analyzed. Results: The BIS had good correlation and prediction probabilities (above 0.5) in the majority of patients; however, BIS was not correlated with EtSevo or the clinical scale of anesthesia in patients with Lennox-Gastaut, West syndrome, cerebral palsy, and epilepsy. BIS showed better correlations than SEF95 and TP. No significant differences were observed between the left- and right-side indexes. Conclusion: BIS may be able to reflect sevoflurane anesthetic depth in patients with some types of ID; however, more research is required to better define the neurological conditions and/or degrees of disability that may allow anesthesiologists to use the BIS.

4D full-field measurements over the entire loading history: Evaluation of different temporal interpolations

  • Ana Vrgoc;Viktor Kosin;Clement Jailin;Benjamin Smaniotto;Zvonimir Tomicevic;Francois Hild
    • Coupled systems mechanics
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    • 제12권6호
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    • pp.503-517
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    • 2023
  • Standard Digital Volume Correlation (DVC) approaches are based on pattern matching between two reconstructed volumes acquired at different stages. Such frameworks are limited by the number of scans (due to acquisition duration), and time-dependent phenomena can generally not be captured. Projection-based Digital Volume Correlation (P-DVC) measures displacement fields from series of 2D radiographs acquired at different angles and loadings, thus resulting in richer temporal sampling (compared to standard DVC). The sought displacement field is decomposed over a basis of separated variables, namely, temporal and spatial modes. This study utilizes an alternative route in which spatial modes are con-structed via scan-wise DVC, and thus only the temporal amplitudes are sought via P-DVC. This meth-od is applied to a glass fiber mat reinforced polymer specimen containing a machined notch, subjected to in-situ cyclic tension, and imaged via X-Ray Computed Tomography. Different temporal interpolations are exploited. It is shown that utilizing only one DVC displacement field (as spatial mode) was sufficient to properly capture the complex kinematics up to specimen failure.

Novel Adaptive De-interlacing Algorithm using Temporal Correlation

  • Ku, Su-Il;Jung, Tae-Young;Jeong, Je-Chang
    • 한국방송∙미디어공학회:학술대회논문집
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    • 한국방송공학회 2009년도 IWAIT
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    • pp.199-202
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    • 2009
  • This paper proposes a novel adaptive algorithm for deinterlacing. In the proposed algorithm, the previously developed Enhanced ELA [6], Chen [9] and Li [10] algorithms were used as a basis. The fundamental mechanism was the selection and application of the appropriate algorithm according to the correlation with the previous and next field using temporal information. Extensive simulations were conducted for video sequences and showed good performance in terms of peak signal-to-ratio (PSNR) and subjective quality.

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北西地中海에 위치하며 염도변화가 심한 부영양화 湖水 Etang de Berre 와 隣接淡水. 海水의 溶存酸素量 硏究 (L'Oxygene Dissous dans une Lagone Eutrophisee a Salinite Variable (Etang de Berre;Mediterranee Nord-Occidentale) et dans les Eaux Douces et Marines Adjacentes)

  • 마르크;김기태
    • 한국해양학회지
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    • 제21권4호
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    • pp.211-228
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    • 1986
  • 北西 地中海에 位置한 Etang de Berre 와 이곳에 流入되는 4개 하천 및 이웃 한 Carry-le-Rouet 海域에서, 1976年 12月까지 용존산소량의 농도와 포화도의 시공간적인 分布가 생태학적 한 요인으로서 조사. 연구되었다.

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Detection of Germline Mutations in Argentine Retinoblastoma Patients: Low and Full Penetrance Retinoblastoma Caused by the Same Germline Truncating Mutation

  • Dalamon, Viviana;Surace, Ezequiel;Giliberto, Florencia;Ferreiro, Veronica;Fernandez, Cecilia;Szijan, Irene
    • BMB Reports
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    • 제37권2호
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    • pp.246-253
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    • 2004
  • Constitutional RB1 gene mutations were studied in a series of 21 families with unilateral and bilateral retinoblastoma patients. Peripheral blood lymphocytes were analyzed by "exon by exon" PCR-heteroduplex and sequencing. Mutations were identified in 6 (29%) of the patients. One mutation corresponded to an intronic polymorphism in g.174351T > A. The other five mutations resulted C to T exonic transitions, four were CGA sequences (g.65386, g.150037 in two patients, and g.162237), creating stop codons and presumably truncated proteins. The fifth one was new and resulted in alanine to valine substitution (g.73774). Two patients had the same the germline truncated mutation (g.150037C > T), one with a familial bilateral early onset retinoblastoma and one with a sporadic unilateral late onset retinoblastoma. The later type has not been previously described. This finding is discussed in the genotype/phenotype correlation context. Additionally, a single nucleotide change was found in six studied samples, where a C to T homozygous transversion was identified in intron 26 (IVS26 + 28). It is worthy the non concordance of the nucleotide with the published sequence. This analysis proved to be a useful method for the detection of mutations in the RB1 gene, and contributed to the adequate genetic counseling to patients and relatives.

Genetic parameters for somatic cell score, milk yield and type traits in Nigerian Dwarf goats

  • Valencia-Posadas, Mauricio;Lechuga-Arana, Alma Arianna;Avila-Ramos, Fidel;Shepard, Lisa;Montaldo, Hugo H.
    • Animal Bioscience
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    • 제35권3호
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    • pp.377-384
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    • 2022
  • Objective: This study was conducted to estimate multi-trait genetic parameters for somatic cell score (SCS), milk yield and type traits in Nigerian Dwarf (ND) goats from the United States. Methods: Data from 1,041 ND goats in the United States with kiddings in 95 herds were used to estimate multi-trait genetic parameters for SCS, milk (MILK), fat (FAT), and protein (PROT) yields, and 14 type traits. An 18-trait mixed linear animal model for lactation mean SCS (Log2), MILK, FAT, PROT, and 14 type traits was applied. A factor analytic approach (FA1) in ASReml software was used to obtain convergence. Results: Averages for SCS were low (2.85±1.29 Log2), and were 314±110.6, 20.9±7.4, and 14±4.9 kg, respectively, for MILK, FAT, and PROT. Heritabilities for SCS, MILK, FAT, and PROT were 0.32, 0.16, 0.16, and 0.10, respectively. The highest heritabilities for type traits were for stature (0.72), teat diameter (0.49), and rump width (0.48), and the lowest estimates were for dairyness (0.003) and medial suspensory ligament (0.03). Genetic correlations of SCS with MILK, FAT, and PROT were positive but low (0.25, 0.18, and 0.23, respectively). Genetic and phenotypic correlations between MILK, FAT, and PROT were high and positive (≥0.66). Absolute values of genetic correlations involving SCS with type traits were generally low or no different from zero. Most of the phenotypic correlations involving SCS with type traits were low. No serious unfavorable genetic correlations between milk yield traits and SCS or between milk yield traits or SCS and type traits were found. Conclusion: Genetic variation exists in the ND breed for most studied traits. The development of selection programs based on these estimates may help accelerate favorable multi-trait genetic changes in this breed.

탈질촉매 내 열화특성과 유동상태에 관한 연구 (A Study on Degradation Characteristic and Flow Behavior in De-NOx Catalyst)

  • 황승민
    • 한국환경과학회지
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    • 제19권9호
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    • pp.1093-1101
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    • 2010
  • In this study, the indirect correlation of degradation characteristic and flow behavior in the de-NOx catalyst is investigated experimentally. The inner flow behavior in the de-NOx catalyst is varied from turbulent flow to laminar flow and the degradation of the de-NOx catalyst is remarkably affected by the inner flow. The degradation of the catalyst is increased in the upstream region near the inlet because injected turbulent flow enhances the adhesion of ash particle on the catalyst surface. The degradation of the catalyst near the inlet also governs the overall efficiency of the catalyst. The amount of adhered ash particles on the catalyst surface decreases as they progress downstream. This is due to the inner flow transition from turbulent flow to laminar flow.

Fast Patch-based De-blurring with Directional-oriented Kernel Estimation

  • Min, Kyeongyuk;Chong, Jongwha
    • 전기전자학회논문지
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    • 제21권1호
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    • pp.46-65
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    • 2017
  • This paper proposes a fast patch-based de-blurring algorithm including kernel estimation based on the angle between the edge and the blur direction. For de-blurring, image patches from the most informative edges in the blurry image are used to estimate a kernel with low computational cost. Moreover, the kernels of each patch are estimated based on the correlation between the edge direction and the blur direction. This makes the final kernel more reliable and creates an accurate latent image from the blurry image. The combination of directionally oriented kernel estimation and patch-based de-blurring is faster and more accurate than existing state-of-the art methods. Experimental results using various test images show that the proposed method achieves its objectives: speed and accuracy.

Comparison of five international indices of adherence to the Mediterranean diet among healthy adults: similarities and differences

  • Aoun, Carla;Papazian, Tatiana;Helou, Khalil;El Osta, Nada;Khabbaz, Lydia Rabbaa
    • Nutrition Research and Practice
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    • 제13권4호
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    • pp.333-343
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    • 2019
  • BACKGROUND/OBJECTIVES: To compare five indices of adherence to the Mediterranean Diet (MD) among adults living in the Mediterranean region. SUBJECTS/METHODS: A total of 100 healthy Lebanese adults aged between 18 and 65 years. Face-to-face interviews to collect sociodemographic and medical information, to take anthropometric measurements, and to fill a validated, culturally adapted, food frequency questionnaire (FFQ). The score for each item was calculated following the recommendations for each corresponding index. The five MD indices were Mediterranean Diet Scale (MDScale), Mediterranean Food Pattern (MFP), MD Score (MDS), Short Mediterranean Diet Questionnaire (SMDQ), and the MedDiet score. RESULTS: Significant correlations were detected between items with P-values < 0.001. Minimal agreement was seen between MDScale and MedDiet score and maximal agreement between MDS and MedDiet score. Univariate and multivariate analyses showed that MDS and MedDiet scores had significant correlations with fiber and olive oil intake, main components of the MD. MDScale showed a significant correlation with waist-to-hip ratio and with total energy intake but none of the five indices was correlated to body mass index (BMI). CONCLUSIONS: The indices that showed the highest correlation with variables related to the MD are the MDScale and the MedDiet score; therefore, they can be used to assess our future study populations. Based on the current results, more than half of the study population was non-adherent to the MD and adherence to this diet did not appear to protect against being overweight ($BMI{\geq}30$).

Increased Expression of HOXB2 and HOXB13 Proteins is Associated with HPV Infection and Cervical Cancer Progression

  • Gonzalez-Herrera, A.L.;Salgado-Bernabe, M.;Velazquez-Velazquez, C.K.;Salcedo-Vargas, M.;Andrade-Manzano, A.;Avila-Moreno, F.;Pina-Sanchez, P.
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권4호
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    • pp.1349-1353
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    • 2015
  • Background: Cervical cancer (CeCa) is the second most common cancer in women in developing countries, and human papilloma virus (HPV) is the primary etiological factor. Aberrant expression of HOX transcription factors has been observed in several types of cancer. To date, however, no reports exist on the expression of HOXB2 and HOXB13 proteins during neoplastic progression in CeCa and its correlation with HPV infection. Materials and Methods: Expression of HOXB2 and HOXB13 proteins was assessed in tissue microarrays from normal cervical epithelium, cervical intraepithelial neoplasias grade 1-3, and CeCa. HPV was detected by PCR and sequencing. Expression of HOX-positive cells was determined in each diagnostic group. Results: Percentage of HOXB2- and HOXB13-positive cells gradually increased from means of 10.9% and 16.7%, respectively, in samples from healthy women, to 75.2% and 88.6% in those from CeCa patients. Frequency of HPV infection also increased from 13% in healthy tissue samples to 92.3% in CeCa. Both HOXB2 and HOXB13 proteins were preferentially expressed in HPV+ samples. Conclusions: The present study represents the first report on the expression of both HOXB2 and HOXB13 proteins through cervix tumorigenesis, providing evidence that increased expression of such proteins is a common event during progression to CeCa.