• Title/Summary/Keyword: cyanoacrylate

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Endovascular Treatment of Incidentally Found Multiple Aneurysms Originating from a Bronchial Artery: A Case Report (우연히 발견된 하나의 기관지 동맥에서 발생한 다발성 동맥류에 대한 혈관내 치료: 증례 보고)

  • Minhyeok Yoon;Jung Guen Cha;Jongmin Park;Sang Yub Lee;See Hyung Kim;Jihoon Hong;Byunggeon Park
    • Journal of the Korean Society of Radiology
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    • v.84 no.5
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    • pp.1191-1196
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    • 2023
  • Bronchial artery aneurysm (BAA) is a rare disease, and multiple aneurysms of a single bronchial artery are rarer. Regardless of the size of the lesion, it is at risk of rupture and can cause massive hemoptysis or severe pain. We report a rare case of bronchial artery embolization (BAE) of multiple aneurysms of a single bronchial artery. During medical examination, a 64-year-old female was diagnosed with multiple BAAs and endobronchial lesions in the right lower lung on CT 10 years prior to presentation to our hospital. Further evaluation of the lesions was recommended; however, the patient was lost to follow-up. The patient complained of dyspnea and visited our hospital, and the size of the BAA had increased on CT. BAE was done successfully using N-butyl-2-cyanoacrylate and detachable coils. Follow up CT after BAE showed significant decrease in extent of inflammatory lesion in the right lung.

Experimental Study on Separation Capacity of Cascade Impactor for Liquid Aerosols

  • Ma, Chang-Jin;Mikio-Kasahara;Park, Kum-Chan
    • Journal of Korean Society for Atmospheric Environment
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    • v.17 no.E1
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    • pp.9-16
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    • 2001
  • To evaluate the correct separation capacity of cascade impactor for liquid aerosol, theoretical and experimental calculations of 50% cut-off diameter(ECOD(sub)50) were performed. A recalculation method of original diameter for hemispheric liquid aerosol collected on casecad impactor is also proposed newly using fixation technique. Calculated values for theoretical (ECOD(sub)50) of 40stage cascade impactor are 20, 6.4, 2.8, and 1.4$\mu\textrm{m}$ at 1st- ,2nd-, 3rd- and 4th-stage, respectively. A good agreement between the result of theoretical (ECOD(sub)50) and that og experimental ones was obtained at Stage 2 and 3. On the other hand, relatively large differences were found at Stage 1 and 4. Fixation for liquid aerosols using ${\alpha}$-cyanoacrylate monomer was performed successfully. The orignal diameter of liquid aerosols collected on each stage was calculated. The maximum levels of number size distribution curves at each stage are 19.8, 6.5, 3.1 and 1.5 $\mu\textrm{m}$ at 1st-, 2nd-, 3rd- and 4th-stage, respectively. The distortion of separation capacity of cascade impactor due to the split, merger, disappearance, and evaporation of liquid aerosols in the fluid did not occur.

"Histologic Examination of Histoacryl When Used in a Subcutaneous Sites.";An Experimental Study (조직접착제인 Histoacryl을 피하조직에 적용하였을 때의 조직학적 소견에 대한 연구)

  • Shin, Dong-Moung;Kim, Jong-Yoo;Lim, Sung-Bin;Chung, Chin-Hyung
    • Journal of Periodontal and Implant Science
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    • v.29 no.4
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    • pp.913-928
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    • 1999
  • Since their discovery in 1949, cyanoacrylates interest many people as possibly being the ideal "Tissue glue". Several different forms of these compounds have been developed in attempt to reduce or eliminate tissue toxicity. Butyl-2-cyanoacrylate(Histoacryl) appears to be the most ideal material as it induces low tissue reactivity & toxicity. In this study, the histotoxic response of histoacryl, when used in a subcutaneous site was compared to a controls which was conventionally sutured. This response was greater than the control that showed no inflammation. However, these findings may not corre-late in actual clinical settings, because most patients tolerate mild degrees of infla-mmation well. Majority of the studies evaluating the histotoxicity of histoacryl have been per-formed when applied superficially & not below the skin surface. This is why further studies are required to evaluate the his-totoxicity of histoacryl when used in a sub-cutaneous site or mucosa.

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Removing Resin Contaminants from the Seated Stone Buddha (Korean Treasure No.84) of Sinboksa Temple Site in Gangneung (강릉 신복사지 석조보살좌상 보물 제84호 수지상 오염물 제거 방안 연구)

  • Lee, Byeonghoon;Go, Hyeongsun
    • Conservation Science in Museum
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    • v.15
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    • pp.56-65
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    • 2014
  • The face of the Seated Stone Buddha Korean Treasure No.84 of Sinboksa Templesite in Gangneung was contaminated with a glossy resin, spoiling its beauty. The contaminants covered the face, the forehead of the urna, to the bottom of the jaw. FT-IR analysis on a sample of the contaminants identified the substance as cyanoacrylate instant adhesive, which can normally be melted with acetone and removed with a swab. However, given that the surface of the statue was severely weathered from prolonged open-air exposure, alternative removal procedures were considered, to minimize the possibility of physical damage. After research, two removal procedures were utilized: one procedure involving poultices, which had been used to remove graffiti from the Samjeondobi Stele, and one procedure involving steam sterilization, which has been used to remove resin from pottery and porcelain. When both the poultices and steam sterilization were applied together, the resin was removed within twenty-four hours, without physical work using a swab.

Effect of Occlusion on the Activities of Dermal Xanthine Oxidase in Rats (흰쥐에 있어서 피부노출 차단이 피부조직의 Xanthine Oxidase 활성에 미치는 영향)

  • 한선일;전태원;윤종국
    • Biomedical Science Letters
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    • v.6 no.1
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    • pp.37-43
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    • 2000
  • To investigate an impact of skin occlusion on the dermal xanthine oxidase (XO) activity, the dorsal part in rats was covered with closed petri dish-shaped chamber, 46 mm in diameter and 10 mm in height, which was made of glass. The crack between top of chamber and skin was sealed by an adhesive agent. After 5 days, the quantity of sweat accumulation was about 400 mg, whereas after 10 days that was decreased about to 21 mg. The 5 days skin occlusion showed the more increased activity of dermal XO compared with the control, and the increased ratio of enzyme activity to the control was higher than that of 10 days skin occlusion, with the increase being associated with sweat accumulation in chamber. Furthermore, the V$_{max}$ of dermal XO in 5 days skin occlusion was higher than that in the control. In conclusion, it may be hypothesized that the XO system may play an role for defence mechanism in dermal tissue.

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EFFECT OF SALIVARY CONTAMINATION OF TEETH ON MICROTENSILE BOND STRENGTH OF VAR10US DENTIN BONDING SYSTEMS. (타액에 의한 오염이 상아질 접착제의 미세전단결합강도에 미치는 영향)

  • Choi, Kyoung-Kyu;Ryu, Gil-Joo
    • Restorative Dentistry and Endodontics
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    • v.28 no.3
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    • pp.203-208
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    • 2003
  • The purpose of this study was to evaluate the effect of salivary contamination of teeth on bonding efficacy of self-priming and self-etching DBSs. The materials used were Single Bond(SB, self-priming system, 3M), Unifil Bond(UB, self-etching system, GC), and Scotchbond Multi-Purpose Plus(SM, 3M) as control. Forty five human molars randomly allocated to three groups as dentin bonding systems tested and embedded in epoxy resin. Then the specimens were wet-ground to expose flat buccal enamel surface or flat occlusal dentin surface and cut bucco-lingually to form two halves with slow speed diamond saw. One of them was used under non-contamination, other under contamination with saliva. The bonding procedure was according to the manufacturer's directions and resin composite(Z-100, 3M Dental Products, St. Paul, MN) was built-up on the bonded surface 5mm high. The specimens were ground carefully at the enamel-composite interface with fine finishing round diamond bur to create an hour-glass shape yielding bonded surface areas of $1.5{\pm}0.1\textrm{mm}^2$. The specimens were bonded to the modified microtensile testing apparatus with cyanoacrylate, attached to the universal testing machine and stressed in tension at a CHS of 1mm/min. The tensile force at failure was recorded and converted to a tensile stress(MPa). Mean values and standard deviations of the bond strength are listed in table. One-way ANOVA was used to determine significant difference at the 95% level. The bond strength of SBMP and SB were not affected by salivary contamination, but that of UB was significantly affected by salivary contamination. These results indicate that DBSs with total etch technique seems less likely affected by salivary contamination in bonding procedure.

INVESTIGATION OF SKIN TYPES BASED ON THE STRATUM CORNEUM LIPID LEVELS

  • Hikima, R.;Ohta, M.;Arai, S.
    • Proceedings of the SCSK Conference
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    • 1999.10a
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    • pp.132-132
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    • 1999
  • In the cosmetics field, facial skins have been classified into four types according to self estimation as well as physiological parameters. The aim of this study is to understand skin condition in the levels and composition of stratum corneum (SC) lipids, and to propose new classification for skin types. We assessed the relationship between the SC lipid composition and the self-estimated skin types or physiological parameters of the skin. Sensitive skin has been of great concern over the last decades, and it should be recognized as a skin type. Therefore, we also investigated the influence of the SC lipid composition on variations of sensitivity evaluated by the Stinging Test. Fifty-five healthy Japanese women aged 22-44 participated in this study. Skin biopsies were taken from facial skin using polyethylene sheet with cyanoacrylate. SC lipids were extracted and separated into individual lipid classes. The combined ceramides and cholesterol were quantified by HPTLC. Free fatty acid was quantified according to the ACS-ACOD method. Instrumental measurements were made at the site around the biopsy. In addition, the Stinging Test and a sensory evaluation questionnaire were administered to all subjects. The generally recognized O-D skin type classification is dependent on the consumer`s subjective assessment with respect to their skin troubles. The product of hydration state and skin surface lipid level showed a significant correlation with self-estimated skin types. The oily-dry skin type classified according to physiological parameters as well as SC lipid levels should be characterized as delicate skin with its barrier function deteriorating in the winter. Two groups of sensitive skin were established. One is the barrier function of the skin is deteriorated, and another is the sebaceous gland activity is in decline.

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Syntheses of Alternating Head-to Head Vinyl Copolymers and Vinyl Terpolymers via Ring-Opening Mechanism. Ring-Opening Polymerization of Substituted-3,4-dihydro-2H-pyrans

  • Lee, Ju-Yeon;Cho, I-Whan
    • Bulletin of the Korean Chemical Society
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    • v.8 no.2
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    • pp.96-101
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    • 1987
  • 2-Ethoxy-6-methoxy-5-cyano-3,4-dihydro-2H-pyran (1_a$), 2-n-butoxy-6-methoxy-5-cyano-3,4-dihydro-2H-pyr an (1b), 2-isobutoxy-6-methoxy-5-cyano-3,4-dihydro-2H-py ran ($1_c$), and 2-ethoxy-6-methoxy-3-methyl-5-cyano-3,4-dihydro -2H-pyran ($1_d$) were prepared by (4 + 2) cycloaddition reaction of methyl $\alpha$-cyanoacrylate with the corresponding alkyl vinyl ethers. Compounds $1_{a-d}$ were ring-open polymerized by cationic catalyst to obtain alternating head-to-head (H-H) copolymers. For comparison, head-to-tail (H-T) copolymer $3_a$ was also prepared by free radical copolymerization of the corresponding monomers. The H-H copolymer exhibited minor differences in its $1_H% NMR and IR spectra, but in the $^{13}C$ NMR spectra significant differences were observed between the H-H and H-T copolymers. Glass transition temperature ($T_g$) of H-H copolymer was higher than that of the H-T copolymer, but thermal decomposition temperature of the H-H copolymer was lower than that of the H-T copolymer. Compounds $1_a$, $a_b$, and $1_c$, copolymerized well with styrene by cationic catalyst, but compound 1d failed to copolymerize with styrene. All of the H-H and H-T copolymers were soluble in common solvents and the inherent viscosities were in the range 0.2-0.4 dl/g.

Stability and Effectiveness of Laser and Liquiband Treatments in the Rat Model of Oral Ulcer

  • Kang, Ji Won;Ryu, Hyun Seok;Abueva, Celine;Chung, Phil-Sang;Woo, Seung Hoon
    • Medical Lasers
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    • v.10 no.4
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    • pp.207-213
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    • 2021
  • Background and Objectives This study was undertaken to assess the stability and efficacy of laser therapy (808 nm), Liquiband (a commercial topical skin adhesive product), and a combination treatment, for application in oral ulcers. Materials and Methods The oral ulcer rat animal model was used to determine the efficacy of photobiomodulation, Liquiband, or combination therapy. Ulcers were induced by injecting 60% acetic acid in the oral mucosa. Three days after ulcer confirmation, the chemically induced ulcers were treated with either laser (808 nm), Liquiband, or a combination of both, every two days for 8 days (4 sessions). Combination therapy was performed by first treating with laser followed by application of the Liquiband. Reduction in ulcer area size was subsequently determined, and animals were sacrificed at 5 and 10 days after the last administration, for histological observation of the extracted oral ulcer tissue samples. Results In this study, treatment with either laser (808 nm) or commercial Liquiband product as well as the combined treatment significantly enhanced oral ulcer healing in the rat animal model. The effect of laser treatment is mainly attributed to collagen synthesis, whereas application of the Liquiband promotes vascularization and formation of granulation tissue. Our results indicate that further optimization of the combined therapy could synergistically and significantly enhance oral ulcer healing. Conclusion Laser or Liquiband treatment of oral ulcer in the rat animal model exert different outcomes, but both methods confirm significant effects relative to the untreated group. The combined treatment group with laser and Liquiband showed marked oral ulcer healing, but further optimization is required to get highly significant results and establish the potential synergistic effect of the combination therapy, as compared to the individual enhancing effects of healing oral ulcers.

Endoscopic Intervention for Anastomotic Leakage After Gastrectomy

  • Ji Yoon Kim;Hyunsoo Chung
    • Journal of Gastric Cancer
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    • v.24 no.1
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    • pp.108-121
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    • 2024
  • Anastomotic leaks and fistulas are significant complications of gastric surgery that potentially lead to increased postoperative morbidity and mortality. Surgical intervention is reserved for cases with severe symptoms or hemodynamic instability; however, surgery carries a higher risk of complications. With advancements in endoscopic treatment options, endoscopic approaches have emerged as the primary choice for managing these complications. Endoscopic clipping is a traditional method comprising 2 main categories: through-the-scope clips and over-the-scope clips. Through-the-scope clips are user friendly and adaptable to various clinical scenarios, whereas over-the-scope clips can close larger defects. Another promising approach is endoscopic stent insertion, which has shown a high success rate for leak closure, although vigilant monitoring is required to monitor stent migration. Infection control is essential in post-surgical leakage cases, and endoscopic internal drainage provides a relatively safe and noninvasive means to manage fluids, contributing to infection control and wound healing promotion. Endoscopic suturing offers full-thickness wound closure, but requires additional training and endoscopic versatility. As a promising tool, endoscopic vacuum therapy potentially surpasses stent therapy by draining inflammatory materials and closing defects. Furthermore, the use of tissue sealants, such as fibrin glue and cyanoacrylate, has been reported to be effective in selected situations. The choice of endoscopic device should be tailored to individual cases and specific patient conditions, with careful consideration of the nature of the defect. Further extensive studies involving larger patient populations are required to provide more robust evidence on the efficacy of endoscopic approach in managing post-gastric anastomotic leaks.