• Journal of Environmental Health Sciences
• /
• v.49 no.1
• /
• pp.11-21
• /
• 2023

Background: The need to develop alternative chemicals is increasing worldwide due to the strengthening of global chemical regulations and consumer safety awareness in the marketplace. Objectives: We aimed to review domestic and foreign technology trends for exploring alternative candidate algorithms that can be used to develop safer alternatives to strengthen global market competitiveness and protect public health in the future. Methods: We searched the current status of research trends, companies related to the development of alternative chemicals in domestic and foreign countries. For this, we referred to research papers and websites by companies and institutes related to such alternatives. Results: Among the domestic and foreign research trends, more studies in South Korea were focused on predicting molecular-based physicochemical properties and toxicity than were reporting on research exploring alternative candidates. Three web-based databases and six tools were being developed. More studies in other countries predicted information to consider in alternative development than reported on research exploring alternative candidates, and four web-based databases and three tools were being developed. Among the companies related to the development of alternative chemicals, 286 alternatives classified as 'EVALUATED ALTERNATIVE' in MARKETPLACE accounted for the most significant proportion in Europe on a continent basis, and the largest number in the United States (US) on a national basis. In South Korea, only significant companies were registered. Conclusions: In this study, it was found to be necessary to provide public technology support platforms to explore alternative candidates considering various aspects in order to support alternative development. In conclusion, exploring alternative candidate algorithms could contribute to the response to the global trends in the chemical industry and to supporting companies and researchers developing safer alternatives in the future.

• Analyses & Alternatives
• /
• v.2 no.2
• /
• pp.111-141
• /
• 2018

By the middle of 2018 there are signs of China's entry into a new period of development, characterized by a change in the old model: "market reforms-inner-party democratization - moderate foreign policy" to another: "market reforms - Xi Jinping personality cult - offensive foreign policy." This model contains the risks of arising of the contradiction between economic freedom and political-ideological rigidity which can lead to destabilization of the political life. However, in the current positive economic dynamics, these risks may come out, rather, in the medium and long term. Today, the political situation in China remains stable - despite growing dissatisfaction in scientific expert and educational circles due to increased control over the intellectual sphere by the authorities. The need for a new redistribution of power between central and provincial authorities could potentially disrupt political stability in the medium term, but, at the moment, is not a critical negative factor. The economic situation is positive-stable. Forecasts indicate a possible increase in China's GDP in 2018 at 6.5%. At the same time, there are negative expectations in connection with the Sino-US and potentially Sino-European "trade war". In the Chinese foreign policy, as a response to Western pressure, China increasingly uses the Russian direction of its diplomacy in the expanded version of Russia + SCO. The nuance here is seen in China's adjusted approach to the SCO: first of all, not as a mechanism for cooperation with Russia, but as an organization that allows using Russia's potential for pressure on the US in the Sino-US strategic rivalry. In the second half of 2018, the Chinese economy will continue to develop steadily, albeit with unresolved traditional problems (debts of provinces and state-owned enterprises, ineffective state sector, risks on the financial and real estate market). In politics, discontent with the cult of Xi will accumulate, but without real threats to its power. Weakening in economic opposition between China and the United States is possible due to Beijing's search for compromises on tariffs, intellectual property, trade deficit. To find such trade-offs, Xi will use the so-called. "Personal diplomacy" of direct contacts with Trump.

• Design Convergence Study
• /
• v.16 no.4
• /
• pp.1-16
• /
• 2017

As the local manufacturing industry has entered a phase of stagnation, service and product design based on user experience has been highlighted as an alternative for the innovation. However, SMEs(Small and Medium-sized Enterprises) are still struggling to overcome the current crisis. One of the reasons is that SMEs do not have enough contact points with the validated UX firms and experts. Thus, SMEs has a high barrier to invest in new opportunity area, user experience. In this study, we aim to figure out UX experts' competence to perform the UX method to solve the UX problems based on the KSA framework(Knowledge, Skill, Attitude). Based on the literature review and expert workshop, we grouped the UX method according to the similarity of the competence required to conduct the method. With cluster analysis, 5 different groups of UX method were defined based on the competence, Panoramic Analysis, Meticulous Observation and Analysis, Intuitive Interpretation, Agile Visualization, and Logical Inspection. The results would be applied to compose a portfolio of UX experts and to implement a mechanism that could recommend the professional experts to the company.

• The Korean Journal of Franchise Management
• /
• v.5 no.1
• /
• pp.109-141
• /
• 2014

Recently, the interests of consumers in firms that implement the social commitment activities have been consistently growing. Consumers' evaluation about the level of corporate social responsibility(CSR) can affect the overall image for product or service of corporation. This recent changes make a marketer to have to consider direct and indirect effects of CSR efforts on the market performance. This phenomena is also found in the franchise industry. The importance of CSR is more critical rather than other industries since each franchisor should care franchisees as well as end users. Franchisors' execution of CSR could increase satisfaction of end user through consonance of activities provided by franchisees. However most franchisor stay in focusing on the traditional CSR activities. Therefore, this study aims to enhance the understanding the CSR in franchise and provide the phase model of CSR development for general firms including franchise. After diagnosis the firms with the proposed model, the study found many franchisors have huge gap between current CSR activities and higher level of CSR policies that franchisor have to make facing. This study call franchisors to reduce this gap by implementing new CSR efforts. If they answer for this calling, franchise industry could leap for making the best practice of creating shared value with other stakeholders.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.28 no.4D
• /
• pp.505-512
• /
• 2008

Over the past years, complex project which has the object to accomplish housing complex, commercial complex etc, recently is changing to multi-complex projects because of development in IT sector. Improvement in the quality of life, life pattern has been and is being changed, these modernized and improved version of life brings the concept of U-city. Department of urban planning and engineering, civil engineering and architecture engineering in every university educate students according to the changing world in order to handle these complex projects in real world. In most cases department of urban planning and engineering teach project planning and department of civil and architecture engineering teach project design and construction. In most of the projects planning followed by design and construction need to be accomplished, but current observation in the present curriculum shows that it is difficult to expect the continuity. The present curriculum of civil engineering has to change as complex projects deal with various different structures during the design and construction phase of these projects. This study examined curriculums from the department of urban and civil engineering related to structural design and construction and survey importance of design works which overlap urban and civil engineering targeted on design engineers. After understanding design works and results obtained from survey we propose for an advanced efficiency method.

• 한국노년학
• /
• v.39 no.2
• /
• pp.325-345
• /
• 2019

The purpose of this study is a exploratory study for understanding the process of the social isolation of the socially isolated elderly through the approach to their life history. The research was analyzed by one of the methods of qualitative research on life history, the conceptual framework of 'Dimensions, turning, and adaptation' of Mandelbaum(1973). According to the results of this study, the socially isolated elderly people were found to be socially isolated by experiencing complex difficulties such as family disconnection, poverty, poor job and health deterioration. Specifically, in the area of life, there was experience of poor relationship with parent, absence of family, poverty of family and unfavorable relationship with surrounding people in life with original family before isolation. They had bad jobs in the labor market, such as hard labor, delivery, business, and chores. In the area of turning point, we experienced family break due to the separation of the original family and the spouse due to various reasons such as financial crisis, parental divorce and death, spouse affair, economic difficulty. In a transitional stage in the life, many reasons such as the financial crisis, the death of parents, the extramarital affair and economic difficulties led to the disconnection from their original family and their spouses. In an adaptive phase, participants accepted the changed life at each turning point in their lives, carrying out their roles, compromising and trying to adapt properly. He said that their current life, which has entered the social safety net system of the people's basic recipients, has led him to live a more stable life and is adapting to personal hobbies and vicarious satisfaction through networks. This result is somewhat different from previous studies in which isolated elderly people were severely exposed to the risk of depression and loneliness. However, we should also consider the characteristics of this study that interviewed elderly people with relatively low isolation. Based on the results of this research, he presented various practical policy implications.

• Journal of the Korea institute for structural maintenance and inspection
• /
• v.27 no.6
• /
• pp.30-38
• /
• 2023

As the number of old buildings subject to safety inspection increases, the burden on designated institutions and management entities that are responsible for safety management is increasing. Accordingly, when selecting buildings subject to safety inspection, appropriate safety inspection standards and appropriate technology are essential. The current safety inspection standards for old buildings give low scores when it is difficult to confirm damage such as cracks in structural members due to finishing materials. This causes the evaluation results to be underestimated regardless of the actual safety status of the structure, resulting in an increase in the number of aging buildings subject to safety inspection. Accordingly, this study proposed a thermal imaging technique, a non-destructive and non-contact inspection, to detect cracks inside finishing materials. A concrete specimen was produced to observe cracks inside the finishing material using a thermal imaging camera, and thermal image data was measured by exciting a heat source on the concrete surface and cracked area. As a result of the measurement, it was confirmed that it was possible to observe cracks inside the finishing material with a width of 0.3mm, 0.5mm, and 0.7mm, but it was difficult to determine the cracks due to uneven temperature distribution due to surface peeling and peeling of the wallpaper. Accordingly, as a result of performing data analysis by deriving the amplitude and phase difference of the thermal image data, clear crack measurement was possible for 0.5mm and 0.7mm cracks. Based on this study, we hope to increase the efficiency of field application and analysis through the development of technology using big data-based deep learning in the diagnosis of internal crack damage in finishing materials.

• Journal of the Korean Association of Geographic Information Studies
• /
• v.26 no.4
• /
• pp.1-16
• /
• 2023

In 2005, the selection of 10 innovation cities was completed, and since 2013, public institutions began relocating to innovation cities. As a policy aimed at promoting balanced regional development, there were significant expectations from the regions. However, although the population moving to innovation cities has increased, it remains to be seen how much inflow is from the capital region and what spatial characteristics exist nationwide. Therefore, this study aims to analyze whether the innovation cities are fulfilling their roles by examining the patterns of inflow from the capital region and the spatial characteristics, and to reassess the policy direction for future innovation cities. We utilized the Microdata Integrated Service (MDIS) provided by Statistics Korea from 2013 to 2021. For the data collection reasons, we focused on analyzing the three cities. The results showed that in the initial stages of innovation city development, there was a significant influx of population from the capital region, leading to some effects on population dispersion and balanced regional development. However, over time, a phenomenon emerged where more people started to move back to the capital region, indicating a problematic trend. Furthermore, the Gyeongbuk Innovation City and Gwangju-Jeonnam Innovation City showed similarities in terms of reasons for migration, age of householder, and number of household members. However, the Gyeongnam Innovation City exhibited distinct characteristics compared to the other two cities. While the reasons for this phenomenon may be diverse, the current situation suggests that the goal of achieving "balanced national development" has reached its limits. Therefore, urgent measures need to be taken for improvement that take regional characteristics into account. Furthermore, in designing the second phase of the public institution relocation plan is required to avoid repeating the same issues and ensure a more thoughtful approach.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
• /
• v.13 no.4
• /
• pp.320-324
• /
• 2008

In order to identify the change of tidal characteristics on average in the Asan Bay due to the construction of the Hwaong (Namyang Bay) tidal barrier (HTB), the tide data at Pyongtack (PT) and Anheung (AH) for the periods from 1993 to 2006 were analyzed using the harmonic analysis method, and major and shallow water tidal constituents were compared. The semidiurnal tidal amplitudes at PT increased while those at AH decreased after the tidal barrier construction. In particular, the amplitudes at PT increased abruptly during the period of $2002{\sim}2003$ when HTB was completed. On the other hand, the amplitudes of the diurnal tides at PT and AH showed minimal change. This suggests that the tidal characteristics change in the Asan Bay may be related to the construction of HTB. The cause of this change is different from either blocking the tidal wave propagation by the Keum River tidal barrier or removing 'choking effect' by the Yeongsan River tidal barrier. The $M_4/M_2$ ratio increased and their phase difference decreased after the completion of HTB. Accordingly, these changes may result in increase of tidal range, decrease of the flood duration and increase of the flood current velocity, inducing more sediments into the Asan Bay.

• Dementia and Neurocognitive Disorders
• /
• v.22 no.3
• /
• pp.100-108
• /
• 2023

Background and Purpose: The efficacy and safety of GV1001 have been demonstrated in patients with moderate-to-severe Alzheimer's disease (AD). In this study, we aimed to further demonstrate the effectiveness of GV1001 using subscales of the Severe Impairment Battery (SIB), which is a validated measure to assess cognitive function in patients with moderate-to-severe AD. Methods: We performed a post hoc analysis of data from a 6 month, multicenter, phase 2, randomized, double-blind, placebo-controlled trial with GV1001 (ClinicalTrials.gov, NCT03184467). Patients were randomized to receive either GV1001 or a placebo for 24 weeks. In the current study, nine subscales of SIB-social interaction, memory, orientation, language, attention, praxis, visuospatial ability, construction, and orientation to name-were compared between the treatment (GV1001 1.12 mg) and placebo groups at weeks 12 and 24. The safety endpoints for these patients were also determined based on adverse events. Results: In addition to the considerable beneficial effect of GV1001 on the SIB total score, GV1001 1.12 mg showed the most significant effect on language function at 24 weeks compared to placebo in both the full analysis set (FAS) and per-protocol set (PPS) (p=0.017 and p=0.011, respectively). The rate of adverse events did not differ significantly between the 2 groups. Conclusions: Patients with moderate-to-severe AD receiving GV1001 had greater language benefits than those receiving placebo, as measured using the SIB language subscale.