• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.1
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• pp.159-164
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• 2016

This paper reports the load factor logic design for a fly-by-wire helicopter flight envelope protection. As a helicopter is very complex system with a rotor, fuselage, engine, etc., there are many constraints on the flight region. Because of these constraints, pilots should consider them carefully and have a heavy workload, which causes controllability degradation. In this respect, automatic logic is needed to free the pilot from these considerations. As one of these logics, the flight envelope protection logic for the load factor of a FBW helicopter was designed. The flight to exceed the load factor is caused by an abrupt pitch cyclic stick change. In this scheme, the load factor limit logic was added between the pilot stick command block and pitch attitude command block. From the current load value, the available attitude range was calculated dynamically and simulated on the helicopter simulator model to verify the performance. A comparison of the simulation results at the hovering and forward speed region with and without applying the load limiting logic showed that the load factor limit was exceeded more than 20% when the logic was not applied, whereas with the load factor limit logic the load factor was within the limit. In conclusion, a dynamically allocated limitation logic to helicopter FBW controller was verified by simulation.

• Journal of Korean Society for Quality Management
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• v.43 no.2
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• pp.141-150
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• 2015

Purpose: The purpose of this paper is to motivate small/medium business challenged masterpiece development and to develop masterpiece strategic system. Methods: Each checklists are developed based on WC300 (World Class 300) and MQI (Masterpiece Quality Index). Correlation between the evaluation items about MQI and WC300 is analyzed. MQI is derived associated with main improvement areas of WC300 through IPA (Importance Performance Analysis). Compliance and ranking are analyzed through HOQ (House Of Quality) using masterpiece quality main factor and limiting factor. Strategy establishment base is secured through improvement derivation and correlation analysis between MQI and GQM 4.0(Global Quality Management 4.0). Results: Detail strategy is derived considering work condition about small/medium business's three kinds of industries (machine, electric and electronic). Conclusion: It is necessary to determine the potential capacity of the current domestic small/medium businesses. Small/medium businesses should be given the opportunity to self identify and manage their strengths and improvement.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.2
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• pp.169-178
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• 2013

Objectives : Many cancers acquired resistance to chemotherapy, thus limiting its anticancer efficacy. It is known that Glutathione (GSH) is related to the development of drug resistance. The expression of GSH synthesizing glutamylcysteine ligase (GCL) was controlled by nuclear factor-E2-related factor(Nrf2). Previous studies showed that pharmacological depletion of GSH results in ROS increase, apoptotic response, and sensitization to oxidizing stimuli. In the current study, we examined Saussurea Lappa (SL) have the inhibitory effect on Nrf2 activity using human lung cancer A549 cells overexpressing Nrf2. Methods : Cell viability of A549 cells on SL treatment was determined by MTT assay. To detect the apeptosis in SL-treated A549 cells, sub-G1 population was measured by flow cytometry analysis (FACS). The level ROS was determined by FACS and fluorescence microscopy. To investigate whether SL have effect the suppression on Nrf2, we performed western blotting analysis. The GSH content was measured since GSH plays an important role in response to oxidative stress and was regulated by Nrf2. Results : A549 cells treated with an SL extract showed a substantial decrease in cell viability, along with a concomitant increase in apoptosis compared to untreated cells. Treatment of the SL extract led to increased Reactive oxygen species (ROS) production and a suppression of Nrf2. In addition, the antioxidant NAC attenuated SL-induced ROS generation, Nrf2 inhibition, and apoptosis. Taken together, these data show that the SL extract induced the production of ROS, and the inhibition of Nrf2, consequently resulting in A549 cell death. Conclusions : These results suggest that SL might be an effective agent to enhance anticancer drug sensitivity via Nrf2 inhibition.

• Journal of the Korean Chemical Society
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• v.57 no.3
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• pp.329-334
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• 2013

A pine needle-embedded graphite enzyme electrode, of which bonding agent is CSM rubber, was newly designed and its electrochemistry was studied based on the amperometry. It involved a ground green leaves of pine tree as a zymogen together with electrochemical mediator, ferrocene within the paste. The plots of ln($i(1-e^{nf{\eta}})$) vs. ${\eta}$ and Lineweaver-Burk at the low potential (-100 to -500 mV) showed good linearities indicating that the amperometric response is by the catalytic power of pine peroxidase. Electrochemical parameters obtained, symmetry factor (${\alpha}$, 0.17), limiting current ($i_1$, 1.99 $A/cm^2$), exchange current density ($i_0$, $5.86{\times}10^{-5}\;A/cm^2$), Michaelis constant ($K_M$, $1.68{\times}10^{-3}$ M) and many others showed that pine peroxidase discharges the role of catalyst quantitatively on the electrode surface. Those proved that the practical use of pine peroxidase is promising in place of the marketed.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.13 no.3
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• pp.178-189
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• 2008

The distribution of inorganic nutrients and their remineralization ratio in the divergence zone ($7^{\circ}{\sim}10.5^{\circ}N$) of the northeastern Pacific were investigated from July 2003 to July 2007. A divergence zone along the boundary of the North Equatorial Counter Current (NECC) and North Equatorial Current (NEC) at $10^{\circ}N$ was observed in July 2007 when the La Nina event and divergence-related upwelling was strong. The mean depth of oligotrophic surface mixed layer in the divergence zone was 46, 61, and 30 m in July 2003, August 2005, and July 2007, respectively. Below the surface mixed layer, a nutricline was clearly observed. The depth integrated value of nitrate including nitrite (DIVn) in the upper layer($0{\sim}100$ m depth) ranged from 5.51 to 21.71 $gN/m^2$(mean 12.82 $gN/m^2$) in July 2003, from 5.62 to 8.46 $gN/m^2$ (mean 7.15 $gN/m^2$) in August 2005, and from 8.98 to 27.80 $gN/m^2$(mean 21.12 $gN/m^2$) in July 2007. The maximum DIVn was observed at the divergence zone. The distributions of phosphate(DIVp) and silicate(DIVsi) were similar to that of DIVn and the DIVn/DIVsi ratio was $0.87{\pm}0.11$ in the upper layer. The limiting nutrient for phytoplankton growth in the study area was identified as nitrogen(N/P ratio=14.6). The nitrate (including nitrite) concentrations were lower in the region mainly affected by NEC than in the region affected by NECC. The study area of low silicate concentrations was also considered to be Si-limiting environment. The remineralization ratios of nutrients were $P/N/-O_2=1/14.6{\pm}1.1/100.4{\pm}8.8(23.44{\leq}Sigma-{\theta}{\leq}26.38)$ in the study area. These ratios suggested remineralization process in the surface layer of divergence zone.

• Journal of Korea Multimedia Society
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• v.17 no.1
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• pp.104-112
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• 2014

With recent development of virtual reality technology, coupled with the growth of the marine industry, virtual underwater simulation systems are under development in various studies, for educational purposes and to simulate virtual reality experiences. Current literature indicates many underwater simulation systems to date have focused on the quality of visual stimulus delivered through three-dimensional graphics user interface, limiting the reality of the experience. In order to improve the quality of the reality delivered by such virtual simulations, it is crucial to develop multi-sensory technology rather than focus on the conventional audio-visual interaction, which limits experiencer from the sense of underwater immersion and existence within the simulation. This work proposes the immersive multi-sensory effector system, delivering the users with a more realistic underwater experience. The sense of reality perceived was evaluated, as the main factor of the virtual reality system.

• Journal of Plant Biotechnology
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• v.40 no.1
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• pp.1-8
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• 2013

Potato is the 4th important crop along with rice, wheat and maize. It contains high quality of starch with relatively high content of vitamin C and protein. However, there is a nutritionally limiting factor due to a low level of sulphur-containing essential amino acid including methionine and cysteine. Recently, recombinant DNA technology and metabolic engineering with genes involved in the bio-synthetic pathway have been applied to enhance the level of these essential amino acids. In this report, it has been discussed about the current status and bottleneck on the development of transgenic potato containing high level of sulphur-containing essential amino acids.

• ALGAE
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• v.23 no.4
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• pp.277-288
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• 2008

The relationship between nutrients and phytoplankton dynamics was investigated daily from 12 April to 22 July 2003 in Sagami Bay, Japan. According to multidimensional scaling (MDS) and cluster analysis, phytoplankton community was divided into four distinct groups. The first group was consisted of centric diatom species, such as Guinardia spp., Detonula spp., Letocylindrus danicus, Skeletonema costatum, Eucampia zodiacus and Chaetoceros spp.. The second and third clusters comprised mainly diatoms and dinoflagellates, respectively. The other cluster was restricted to the samples collected during the last sampling period when the rainfall and river discharge was frequently recorded. Canonical correspondence analysis (CCA) was applied to analyze four groups respectively, which focused on the effects of nutrients concentration and ratio on phytoplankton variations. Based on CCA analysis, most species of centric diatom were negatively correlated with DSi concentrations and Si/N ratio. Nutrients were strongly limited phytoplankton growth during the summer when the rainfall was not observed, whereas river discharge by rainfall and counterclockwise coastal currents (although the surface circulation pattern is often altered by Kuroshio Current, the counterclockwise coastal currents are generally dominant) has brought phytoplankton population accumulation and triggered the micoalgae growth in western part of the bay. Phosphorous (P) was strongly limited after significantly increases in the phytoplankton abundances. However, silicate (Si) was not a major limiting factor for phytoplankton production, since Si/DIN and Si/P ratio did not create any potential stoichiometric limitation. This indicates that high Si availability contributes favorably to the maintenance of diatom ecosystems in Sagami Bay.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.62 no.6
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• pp.798-802
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• 2013

In a conventional DC power supply used for CO2 laser, the circuit elements such as a rectifier bridge, a current-limiting resistor, a high voltage switch, energy storage capacitors ans a high-voltage isolation transformer using high turn ratio are necessary. Consequently, those supplies are expensive and require a large space. Thus, laser resonator and power supply should be optimally designed. In this paper, we propose a new power supply using high frequency resonance phenomena for CW(Continuous wave) CO2 laser (maximum output of 23W with discharge length of 450mm). It consists of a transformer including leakage inductance, magnetizing inductance and half-bridge converter, a three-stage Cockcroft-Walton and PFC(Power factor correction) circuit. The output ripple voltage can be controlled the minimum of 0.24% under the high frequency switching of 231kHz. Furthermore, the output efficiency was improved to 16.4% and the laser output stability of about 5.6% was obtained in this laser system.

• YAKHAK HOEJI
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• v.52 no.6
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• pp.471-479
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• 2008

The purpose of this study is to investigate the best way that Oriental medicine contributes for activation of pharmacy management after the separation of prescribing and dispensing practice since July 2000. In order to investigate current pharmacy conditions for handling of Oriental medicine and many problems for administering the Oriental medicine to patients, a questionnaire was written with a list of questions related to pharmacy management with Oriental medicine, and given to 58 subjects via fax or personal visit during the period of April 21 to 30, 2003. The research results was as follows; In th 58 subjects, 45 subjects (77.6%) were pharmacists with a licence for dispensing Oriental medicine. 70.7% of subjects most likely preferred to extract granule as administering type of oriental medicine. About the motivation using Oriental medicine, the reason for activation of pharmacy management was 39.7%, second, the reason for resolving the limitation of treatment over western medicine was 25.9%. Oriental medicine for patients was mainly administered by recommendation with pharmacist (65.5%). In comparison with after and before the separation of prescribing and dispensing, 51.7% of subjects answered that sale volume was decreased after the separation. Concerning the ratio of total sales volume to Oriental medicine within 5 years, 50% of subjects expected that sales volume will increase positively. About treating Oriental medcine, 34.5% of subjects thought the problem is the regulation by limiting 100 kinds of formulary. The most important factor for increasing Oriental medicine selling amount was continueous education for various information of oriental medicine in case of 44.8% of sujects. The best pharmacy to handle oriental medicine was community pharmacy (36.2%). It was expressed the reason why many pharmacists have not been treated oriental medicine because lots of time needs for dispensing prescription from clinics in these 4 years after the separation of prescribing and dispensing. These results lead to the conclusion that the Oriental medicine at pharmacy will greatly increase within 5 years and will be very important portion for pharmacy management.