• Title/Summary/Keyword: culture status

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Current status and clinical application of patient-derived tumor organoid model in kidney and prostate cancers

  • Eunjeong Seo;Minyong Kang
    • BMB Reports
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    • v.56 no.1
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    • pp.24-31
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    • 2023
  • Urological cancers such as kidney, bladder, prostate, and testicular cancers are the most common types of cancers worldwide with high mortality and morbidity. To date, traditional cell lines and animal models have been broadly used to study pre-clinical applications and underlying molecular mechanisms of urological cancers. However, they cannot reflect biological phenotypes of real tissues and clinical diversities of urological cancers in vitro system. In vitro models cannot be utilized to reflect the tumor microenvironment or heterogeneity. Cancer organoids in three-dimensional culture have emerged as a promising platform for simulating tumor microenvironment and revealing heterogeneity. In this review, we summarize recent advances in prostate and kidney cancer organoids regarding culture conditions, advantages, and applications of these cancer organoids.

Determinants of Physical Frailty among Old-Old Adults in an Urban-Rural Complex Community in Korea

  • Chang, HeeKyung
    • International Journal of Advanced Culture Technology
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    • v.11 no.3
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    • pp.131-141
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    • 2023
  • This study aimed to identify the determinants of physical frailty among the old-old adults in rural Korean communities. A total of 191 individuals aged 75 and older were included in the study, with the majority being female. Participants were classified into healthy (n=47), pre-frail (n=54), and frail (n=90) groups. Significant differences were found across these groups in terms of age, gender, education level, depression, and nutritional status. Multiple logistic regression analysis revealed that age (OR=1.16), depression (OR=0.21), malnourishment (OR=10.85), and short physical performance ability (OR=0.70) were significant predictors of physical frailty. These findings underscore the multifaceted nature of physical frailty among old-old adults in urban-rural complex communities and highlight the need for comprehensive and integrated interventions. Such interventions should consider not only physical factors but also broader health conditions and socio-demographic influences impacting the elderly. Further research is needed to develop and evaluate interventions that address these determinants and promote health equity among the elderly population in urban-rural complex communities

Global Fashion Brand Non-Fungible Token (NFT) Application Case Study

  • Hye-Sook Park;Phil-Joo Moon
    • International Journal of Advanced Culture Technology
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    • v.11 no.3
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    • pp.315-320
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    • 2023
  • Covid-19 is rapidly changing the global society. In particular, as the online connected world has become more important in recent years, new communication methods such as VR, AR, and metaverse have emerged as global trends. As social interest in technologies such as metaverse, blockchain, and NFT continues to grow, this study aims to understand the concept of NFT, which is being illuminated as a global trend keyword, and to examine the current status of the global fashion industry. As a result of examining NFT application cases of fashion brands that have grown rapidly since Covid-19, the use of NFT in the global fashion industry can be largely classified into three categories - Collection and Investment Type, Game Type NFT, Marketing and Event Type NFT. Based on this, We expect that this study will be used as basic data to actively utilize NFT, which is still in its infancy, to prepare a plan to revitalize the domestic fashion industry.

A Study on Purchasing Current Status and Promotion Facts for Commercial Kimchi of Women in Seoul Area (서울지역 여성의 시판 김치 구입현황과 구매촉진에 관한 연구)

  • Joo, Na-Mi;Kim, Ok-Sun
    • Journal of the Korean Society of Food Culture
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    • v.22 no.2
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    • pp.167-175
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    • 2007
  • This study was to investigate purchase of women for commercial kimchi. Survey was carried out by questionnaire method that is target on 322 female over 20 age in Seoul area. The results of the study was that the way they get kimchi of women answered that they make it by themselves(63.3%). The reason of purchasing is they do not have enough time to make it at their home(43.8%) and its good taste(56.8%) result in their purchase. In the degree of preference about package material, prefer polyethylene(39.6%). Also respondents prefer purchasing poggi kimchi(63.4%) among other different types of kimchi. The promotion facts of purchasing commercial kimchi shows a high score in cold chain system package and specific kimchi development.

The Antecedents and Consequences of Ethical Leadership in the Restaurant Industry -Focused on Ethical Context, Personality, and Job Satisfaction- (레스토랑에서의 윤리적 리더십에 관한 연구)

  • Ha, Dong-Hyun;Lim, Jung-Woo
    • Journal of the Korean Society of Food Culture
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    • v.23 no.5
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    • pp.563-571
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    • 2008
  • The purpose of this study was to investigate how organization's ethical context, leader's agreeableness, conscientiousness and neuroticism affected his (or her) ethical leadership, and how leader's ethical leadership influenced subordinates' job satisfaction in the restaurant industry. The model was tested in hotel restaurants and family restaurants using a sample of employees in Pusan, Daegu and Gyeongsangbukdo. Empirical results confirmed that organization's ethical context, leader's agreeableness, conscientiousness and neuroticism influenced his (or her) ethical leadership, and leader's ethical leadership affected subordinates' job satisfaction. This research findings implied managerially that firstly, top management should establish employees' ethical regulations and motivate them to work ethically through training, incentives and punishment and secondly, should employee agreeable, conscientious and anti-neurotic person through aptitude test, if possible. In the future, restaurant's successful operations and management depends on partly its ethical status.

Career Exploration for Customized Career Curriculum Design

  • Do-Young Lee
    • International Journal of Advanced Culture Technology
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    • v.11 no.4
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    • pp.169-176
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    • 2023
  • This study aims to assess the current status of career education at C University and to gather foundational data for developing a step-by-step career education curriculum and an integrated roadmap for curriculum and extracurricular career education. This research involves a comparative analysis of C University's enrolled students and external university students through a survey using the [University Career Exploration Model]. Data collection took place over one month in October 2023, and statistical analysis was conducted using the SPSS Statistics 25.0 program. The survey results enabled a comparative analysis of the career exploration processes and levels between enrolled students at C University and external university students. The proportion of enrolled students at C University responding positively to the career exploration process and level was high. Through this study, a better understanding of the career exploration processes and levels of university students was achieved. It is deemed necessary to conduct systematic research for continuous, tailored integration of curriculum and extracurricular career education at the university level.

Analysis of the Structural Characteristics of Technology Fusion Networks Using the International Patent Classification: Focusing on Patents in the Pet Food Industry

  • Yun-Ju Lee;Joon-Seok Song
    • International Journal of Advanced Culture Technology
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    • v.12 no.1
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    • pp.134-143
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    • 2024
  • We investigated and analyzed the technological landscape of the global pet food industry, focusing on related industries in Korea and abroad. This industry accounts for the largest share of the rapidly growing global pet market. We aimed to identify and develop technologies that can strengthen Korea's position in this market. Our study employed various quantitative methods, including time series analysis, country and applicant analysis, and International Patent Classification (IPC) technology analysis. These analyses allowed us to objectively assess the current technological status, patent application distribution, and technological trends in the pet food industry. Our findings revealed that the United States currently holds the leading position in terms of patent applications within the pet food industry. This suggests that to establish a differentiated competitive edge in this field, it's crucial to develop technologies with high usability and target specific segments within related industries. Additionally, focusing on interdisciplinary research that combines Korea's existing advanced technologies with other relevant fields is essential.

Effects of Special Mouth Care with an Aroma Solution on Oral Status and Oral Cavity Microorganism Growth in Elderly Stroke Patients (아로마 용액을 이용한 구강간호가 뇌졸중 노인의 구강상태와 구강 세균 집락에 미치는 효과)

  • Lee, Eun-Hye;Park, Hyojung
    • Journal of Korean Academy of Nursing
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    • v.45 no.1
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    • pp.46-53
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    • 2015
  • Purpose: This study was conducted to examine the effect of oral care with an aroma solution on oral status and oral cavity microorganism growth in elderly patients with stroke. Methods: A non-equivalent control group, with a pretest-posttest design was used in this study. The participants were assigned to the experimental group (n=30) that received oral care with an aroma solution or the control group (n=31) that received 0.9% saline solution. To identify the effect of the experimental treatments, objective/subjective assessments of oral status and oral cavity microorganism growth were performed using the oral assessment guide, oral perception guide, and oral swab culture. Data were analyzed using Chi-square test, Fisher's exact test, and t-test with the SPSS version 21.0 program. Results: The objective oral status was significantly lower in the experimental group than in the control group (t= -3.64, p<.001). There was no significant difference between the subjective oral status of the experimental group and control groups (t= -1.24, p=.109). Oral microorganism growth was significantly lower in the experimental group than in the control group (t= -7.39, p<.001). Conclusion: These findings indicate that special mouth care using an aroma solution could be an effective oral health nursing intervention for elderly patients with stroke.

Interpretation of Korean Housing in the Period of Opening the Country to the West and its Modernity Focussed on the Civilization Theory (문명화이론을 통해 본 개항기의 주거와 그 근대성의 재조명)

  • 전남일
    • Journal of Families and Better Life
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    • v.21 no.5
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    • pp.25-40
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    • 2003
  • Since Korea open her ports to the West, she had undergone a great change under the alien influences both on the macro-social and micro-social aspects. This study aims to review the korean housing, corresponding with the everyday life, during the period of transition between the 1876 - 1910 and to interpret its process of modernization and the meaning of modernity. With regards to understand the holistic human relationship and place pf living through history, this study takes the Nobert Elias' Civilization Theory as a theoretical basis. References were therefore, made to various records of foreign missionary at the time, with respect not only to macro sociological changes but also to changes of everyday life. It is of course to take physical and structural aspects of housing architecture into consideration. These works, thus, led to presuming the housing culture of said period. In order to investigate modern character of korean housing, distinctively represented by spatial structure, considerations were made to various architectural examples according to the social and residential status both in urban and rural area. As a results, this paper came to the remarks as follows; 1. It is understood, that the process of modernization is a part of the process of civilization as synthetic process. It is integrated with the change of socio-cultural aspects and everyday life. 2. Korean housing in the said period shows various different residential status and grade of civilization according to the social status as well as economical status. Modern housing was not in general yet. 3. Housing for high classes and middle classes in Seoul shows a tendency of assimilation and imitation after western model. But some examples within the housing of high classes represent its own modernity, that is based on the rationalism and equalization 4. In the housing of lower classes, it was very far from the benefits of civilization. It could analogize from the immature control of disgrace, from undevelopment of individual territory and from uncultivation of rationality in the housing space.

Effects of Oral Care with 0.1% Chlorhexidine and Tantum Solution on Oral Status and Incidence of Oral Pathogens among Intubated ICU Patients: A Pilot Study (0.1% 클로르헥시딘과 탄툼액을 이용한 구강간호가 기관내관을 삽입한 중환자실 환자의 구강상태 및 구강내 세균 발생에 미치는 효과)

  • Lee, Kyung-Hee;Park, Hae-Kyung;Kim, Ji-Hye
    • Journal of Korean Critical Care Nursing
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    • v.3 no.2
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    • pp.25-35
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    • 2010
  • Purpose: The purpose of this pilot study was to investigate the effect of oral care using 0.1% chlorhexidine and tantum solution on oral status and incidence of oral pathogens among intubated ICU patients. Methods: The study subjects were 26 intubated patients of MICU in a university hospital. Oral care was provided with 0.1% chlorhexidine solution to the experimental group (n=12) and with tantum solution to the control group (n=14), 3 times a day for 6 days. After the intervention, the oral status of each subject was checked using structured method, and oral swab culture was done to count colonized bacterial pathogens. Results: The mean oral status score of experimental group was significantly higher than that of control group (U=42.50, p=.031). The mean incidence of oral pathogens in experimental group was smaller than that of control group, but the difference was not statistically significant. Conclusion: The oral care with 0.1% chlorhexidine solution is more effective than with tantum solution for improving oral status of intubated ICU patients. However, additional studies with larger sample size will be needed to figure out it's effects on the incidence of oral pathogens.

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