• Journal of the Earthquake Engineering Society of Korea
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• v.11 no.2 s.54
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• pp.1-9
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• 2007

The method of generating the artificial acceleration time histories for seismic analysis based on genetic algorithms is presented. For applying to the genetic algorithms, the frequencies are selected as the decision variables eventually to be genes. An arithmetic average crossover operator and an arithmetic ratio mutation operator are suggested in this study. These operators as well as the typical simple crossover operator are utilized in generating the artificial acceleration time histories corresponding to the specified design response spectrum. Also these generated artificial time histories are checked whether their outward features are to be coincident with the recorded earthquake motion or not. The features include envelope shape, correlation condition between 2 horizontal components of motion, and the relationship of max. acceleration, max. velocity and max. displacement of ground.

• Transactions of the Korean Society of Automotive Engineers
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• v.6 no.4
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• pp.76-85
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• 1998

Recently, Genetic Algorithm(GA) is widely adopted into a search procedure for structural optimization, which is a stochastic direct search strategy that mimics the process of genetic evolution. This methods consist of three genetics operations maned selection, crossover and mutation. Contrast to traditional optimal design techniques which use design sensitivity analysis results, GA, being zero-order method, is very simple. So, they can be easily applicable to wide area of design optimization problems. Also, owing to multi-point search procedure, they have higher probability of converge to global optimum compared to traditional techniques which take one-point search method. In this study, a method of finding the optimum values of suspension parameters is proposed by using the GA. And vehicle is modelled as planar vehicle having 5 degree-of-freedom. The generalized coordinates are vertical motion of passenger seat, sprung mass and front and rear unsprung mass and rotate(pitch) motion of sprung mass. For rapid converge and precluding local optimum, share function which distribute chromosomes over design bound is introduced. Elitist survival model, remainder stochastic sampling without replacement method, multi-point crossover method are adopted. In the sight of the improvement of ride comfort, good result can be obtained in 5-D.O.F. vehicle model by using GA.

• Archives of Pharmacal Research
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• v.18 no.4
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• pp.237-242
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• 1995

For the vioequivalence study of two ceftriaxone injection formulations ($Rocephin{\circledR}$ ; Roche, and Triaxone ; Hanmi0, the HPLC analytical method for the analysis of ceftriaxone in plasma was used. Fourteen healthy volunteers completed the study and each subject were IM in jected signle doses (1 g) of the test and the reference formulations in a two-way crossover design with an one week drug free interval between doses. Following each administration, plasma concentrations of ceftrixone were monitored over a period of 24 h. Bioequivalence parameters $AUC_{24th}, {\;}T_{max}, {\;}C_{max}$ and MRT determined from the data obtained for the two formulations were examined by analyses of variance (ANOVA) and other criteria and tests for bioequivalence. Results of ANOVA and confidence limits of test/reference ratios of $AUC_{24th}, {\;}T_{max}, {\;}C_{max}$ and MRT, and statistical tests indicated the bioequivalence of the two formulations (i.e., test/reference ratio was within $100{\pm}20%$) except for $T_{max}$ The mean of $T_{max}$ showed only 6. 9% difference from the reference but the detection limit was 22.5% which is slightly over the 20% criteria. No pharmacokinetic parameters including Ka, Kel, Vd and Cl indicated significant difference in between the two fomulations. It was concluded that the data yielded fro the two cefriaxone formulations demonstrated that they were bioequivalent.

• Journal of Microbiology and Biotechnology
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• v.27 no.2
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• pp.405-411
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• 2017

Homologous recombination occurs between homologous chromosomes and is significantly involved in programmed double-strand break (DSB) repair. Activation of two recombinases, Rad51 and Dmc1, is essential for an interhomolog bias during meiosis. Rad51 participates in both mitotic and meiotic recombination, and its strand exchange activity is regulated by an inhibitory factor during meiosis. Thus, activities of Rad51 and Dmc1 are coordinated to promote homolog bias. It has been reported that Hed1, a meiosis-specific protein in budding yeast, regulates Rad51-dependent recombination activity. Here, we investigated the role of Hed1 in meiotic recombination by ectopic expression of the protein after pre-meiotic replication in Saccharomyces cerevisiae. DNA physical analysis revealed that the overexpression of Hed1 delays the DSB-to-joint molecule (JM) transition and promotes interhomolog JM formation. The study indicates a possible role of Hed1 in controlling the strand exchange activity of Rad51 and, eventually, meiotic crossover formation.

• Journal of the Korean Data Analysis Society
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• v.20 no.6
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• pp.2865-2872
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• 2018

In the field of data mining technique, there are various methods such as association rules, cluster analysis, decision tree, neural network. Among them, association rules are defined by using various association evaluation criteria such as support, confidence, and lift. Agrawal et al. (1993) first proposed this association rule, and since then research has been conducted by many scholars. Recently, studies related to crossover entropy have been published (Park, 2016b). In this paper, we proposed a purely symmetric J measure considering directionality and purity in the previously published J measure, and examined its usefulness by using examples. As a result, it is found that the pure symmetric J measure changes more clearly than the conventional J measure, the symmetric J measure, and the pure crossover entropy measure as the frequency of coincidence increases. The variation of the pure symmetric J measure was also larger depending on the magnitude of the inconsistency, and the presence or absence of the association was more clearly understood.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2006.05a
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• pp.172-175
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• 2006

유전자 알고리즘은 탐색 공간에서 새로운 샘플을 찾기 위하여 선택과 재조합의 연산을 사용하는 모집단 기반 모델이다. 교차 연산은 최적화 알고리즘인 유전자 알고리즘(GA)에서 가장 중요한 부분을 차지한다. 이 논문에서는 교차 연산 수행 시 필요한 교차점 위치 조절이 수렴에 어떠한 영향을 주는지 분석해 보고자 한다. 교차점 위치를 세대 진행수와 수렴 정도에 따라 특정 위치로 조절한 방법이 일반적인 확률로 교차점 위치를 정하여 최적화를 수행한 경우보다 전역 해를 더 빨리 찾아감을 볼 수 있었다.

• Proceedings of the Korea Multimedia Society Conference
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• 2004.05a
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• pp.421-424
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• 2004

음성 중심의 기존 2G CDMA/PCS 시스템과 달리 CDMA2000 및 1xEV-DO와 같은 차세대 이동통신 시스템에서 패킷 데이터 서비스가 부각됨에 따라 효율적인 망의 설계 및 디멘져닝을 위해서는 무엇보다도 데이터 트래픽의 주요 특성인 버스트(Burst)와 자기유사성(Self-similarity)이 반영된 모델이 요구된다. 본 논문에서는 차세대 이동통신 시스템에서 자기유사 특성을 갖는 트래픽의 큐잉 성능을 시뮬레이션 하였고, 그 결과를 해석적 모델과 비교하였다. 또한 Crossover point의 변화와 출력링크의 변화도 분석하였다.

• Journal of the Korean earth science society
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• v.26 no.8
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• pp.836-843
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• 2005

Two data sets of repeated hydrographic surveys with a single beam echo-sounder were obtained to investigate morphological changes on a sand mining site within EEZ near the Eocheong Islands, West Sea of Korea. Their accuracies of depth measurement, estimated from the crossover analysis, correspond to the Oder 2 of IHO standards. Bathymetric maps show a feature of 300m wide and 10m deep hollow, whose evolution can be seen in difference grids of the two bathymetric maps. However, data of higher accuracy and resolution enable precise quantification of extracted sand volume. Since this morphological change could affect sedimentary environment as well as benthic ecology, environmental impact assessment based on scientific research data is required for management and sustainable development of limited sand resource.

• Steel and Composite Structures
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• v.7 no.6
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• pp.421-440
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• 2007

An optimal design method in cooperated with nonlinear inelastic analysis is presented. The proposed nonlinear inelastic method overcomes the difficulties due to incompatibility between the elastic global analysis and the limit state member design in the conventional LRFD method. The genetic algorithm used is a procedure based on Darwinian notions of survival of the fittest, where selection, crossover, and mutation operators are used to look for high performance ones among sections in the database. They are satisfied with the constraint functions and give the lightest weight to the structure. The objective function taken is the total weight of the steel structure and the constraint functions are load-carrying capacity, serviceability, and ductility requirement. Case studies of a planar portal frame, a space two-story frame, and a three-dimensional steel arch bridge are presented.

• The Transactions of the Korean Institute of Electrical Engineers B
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• v.52 no.5
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• pp.230-237
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• 2003

Current mode control has been used for DC to DC converters for over twenty years. There are many different control schemes which use the inductor current signal in one way or another to control the DC to DC converter. In this paper, the state space averaging technique is applied for the analysis of flyback type current mode control circuit. We made real converter for the guarantee of stable output characteristic and proper design of feedback circuit. The validity of proposed method is verified from test result. The improvement of stability is confirmed by sinusoidal signal injection method with isolated transformer. It is known that phase margin is sufficient and gain crossover frequency fc is early 1/5 of switching frequency, fs, from the experimental result with frequency response analyzer.