• Proceedings of the Korea Multimedia Society Conference
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• 2004.05a
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• pp.421-424
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• 2004

음성 중심의 기존 2G CDMA/PCS 시스템과 달리 CDMA2000 및 1xEV-DO와 같은 차세대 이동통신 시스템에서 패킷 데이터 서비스가 부각됨에 따라 효율적인 망의 설계 및 디멘져닝을 위해서는 무엇보다도 데이터 트래픽의 주요 특성인 버스트(Burst)와 자기유사성(Self-similarity)이 반영된 모델이 요구된다. 본 논문에서는 차세대 이동통신 시스템에서 자기유사 특성을 갖는 트래픽의 큐잉 성능을 시뮬레이션 하였고, 그 결과를 해석적 모델과 비교하였다. 또한 Crossover point의 변화와 출력링크의 변화도 분석하였다.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.18 no.33
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• pp.111-118
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• 1995

This paper suggests a hybrid genetic algorithm for asymmetric traveling salesman problem(TSP). The TSP was proved to be NP-complete, so it is difficult to find optimal solution in reasonable time. Therefore it is important to develope an algorithm satisfying robustness. The algorithm applies dynamic programming to find initial solution. The genetic operator is uniform order crossover and scramble sublist mutation. And experiment of parameterization has been performed.

• Proceedings of the Korean Magnestics Society Conference
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• 2008.06a
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• pp.108-108
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• 2008

• Journal of the Korean Society of Clothing and Textiles
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• v.24 no.4
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• pp.463-474
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• 2000

The purposes of this study is to investigate the characteristics of historicism in modern fashion and to introduce the appropriate approaching and application method of costume history. As one of the characteristic of Post modernism, historicism is an important theme in modern fashion. In this study, the background and the characteristic of Post modernism is considered and the historicism in the Post modern architecture and literature is studied. Next, through the artworks of Vivienne Westwood and Christian Lacroix who are excellent in the modernization of historical costume, the historicism in modern fashion is studied. The characteristic of historicism in Post modem architecture and literature comes from the nostalgia, aspiration for the past, and recurrence to the nature. It is not the revival of the past but the crossover of the past and the present. The characteristics of historicism in modern fashion are as follows. ·form; style, silhouette, and items that are shown in the historical costume come with the mixture of modem textile, new technique, and modem design. ·Materials and patterns; classical and romantic patterns, the artwork of the artist, and the fabric which is remake of remains are used. ·Technique; Tailoring techniques and the pattern making of the historical costume are used. ·Trimmings and etc.; Lots of handworks, trimmings and accessaries in that are inspired from the past are used. These elements are not come from a certain place and time but mixed surpassing places and times. With that, not only the form and the position of wearing but the meaning and purpose of wearing are changed.

• The Journal of Internal Korean Medicine
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• v.33 no.4
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• pp.511-519
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• 2012

Objectives : This study investigated the effect of Sinseonbulchuidan (SBD-1) on hangover syndrome. We undertook this study to test whether SBD-1 is effective in preventing the signs and symptoms of alcohol-induced hangover. Methods : Fifteen healthy volunteers participated in this double-blind randomized crossover study. All participants received either SBD-1 or indistinguishable placebo capsules before alcohol consumption. The primary outcome measure was the difference in hangover severity scores between SBD-1 and placebo intervention. Secondary outcome measure was the difference in profile of mood states (POMS) between SBD-1 and placebo intervention. Results : After alcohol exposure, the overall symptom scores were significantly decreased in the SBD-1 group compared with those given a placebo. The mean scores for the hangover symptoms were high in the placebo group, and statistical significance was observed in 4 symptom scores (loss of appetite, stomachache, nausea, and total score). There were no differences in the POMS and cognitive performance test results between SBD-1 and placebo intervention. Conclusions : We conclude that the SBD-1 is effective in preventing the signs and symptoms of alcohol-induced hangover. Larger studies are required to confirm these findings.

• Clean Technology
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• v.10 no.1
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• pp.9-17
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• 2004

Direct methanol fuel cell(DMFC) with proton exchange membrane (PEM) has advantages over the conventional power source (e.g. vehicle). DMFC, however, has a problem to be solved such as methanol crossover, high anodic overpotential and limiting current density, etc. The physicochemical phenomena in DMFC can be described by coupled PDEs (partial differential equations), which can be solved by a PDE solver. In this paper, we utilized a commercial software FEMLAB to solve the PDEs. The FEMLAB is one of the software programs available which are developed as a solver for building physics problems based on PDEs and is designed to simulate systems of coupled PDEs which may be 1D, 2D, 3D, non-liner and time dependent. We performed simulation using the Tafel equation as an electrochemical reaction model to analyze methanol concentration profile in DMFC system. We confirm that the rapid decrease of methanol concentration at anodic catalyst layer with the increase of the current density is a main reason of the low performance in DMFC through simulation results.

• Journal of the Korean Institute of Intelligent Systems
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• v.11 no.6
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• pp.538-542
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• 2001

DNA computing has been applied to the problem of getting an optimal soluting since Adleman's experiment. DNA computing uses strings with various length and four-type bases that makes more useful for finding a global optimal solutions of the complex multi-modal problems This paper presents DNA coding method finding optimal solution of the multi-modal function and compares the efficiency of this method with the genetic algorithms(GA). GA searches efffectively an optimal solution via the artificial evolution of individual group of binary string and DNA coding method uses DNA molecules and four-type bases denoted by the A(Ademine) C(Gytosine);G(Guanine)and T(Thymine). The selection, crossover, mutation operators are applied to both DNA coding algorithm and genetic algorithms and the comparison has been performed. The results show that the DNA based algorithm performs better than GA.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.6
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• pp.1251-1255
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• 2011

In this paper, we propose an optimal path search algorithm that contains all nodes using genetic algorithm. An object in this approach is formed as an equation related with the Euclidean distance between an intermediate node and the starting node and between an intermediate node and the goal node. Like other genetic algorithm structures, our algorithm defines a fitness function and selects a crossover spot node and a bitwise crossover point. A new node out of such operation survives only if it satisfies the fitness criteria and that node then becomes the starting node for the next generation. Repetition continues until no changes are made in the population. The efficiency of this proposed approach is verified in the experiment that it is better than two other contestants - sequential approach and the random approach.

• Journal of Pharmaceutical Investigation
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• v.35 no.4
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• pp.287-293
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• 2005

The purpose of the present study was to evaluate the bioequivalence of two glimepiride tablets, Amaryl tablet (Handok & Aventis Korea, reference drug) and Mepiril tablet (Myungmoon Pharm. Co., Ltd., Korea, test drug), according to the guidelines of Korea Food and Drug Administration (KFDA). After adding an internal standard (glibenclamide) to human plasma, plasma samples were extracted using 1mL of methyl tertiary butyl ether. Compounds extracted were analyzed by reverse-phase HPLC with multiple reaction monitoring (MRM) mode analyte detection. This method for determination glimepiride proved accurate and reproducible, with a limit of quantitation of 2 ng/mL in human plasma. Twenty-four healthy male Korean volunteers received each medicine at the glimepiride dose of 2 mg in a $2{\times}2$ crossover study. There was a one-week washout period between the doses. Plasma concentrations of glimepiride were monitored by a LC-MS/MS for over a period of 12 hr after the administration. $AUC_t$ (the area under the plasma concentration-time curve from time zero to 12 hr) was calculated by the linear trapezoidal rule method. $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were compiled from the plasma concentration-time data. Analysis of variance was carried out using logarithmically transformed $AUC_t$ and $C_{max}$. No significant sequence effect was found for all of the bioavailability parameters indicating that the crossover design was properly performed. The 90% confidence intervals of the $AUC_t$ ratio and the $C_{max}$ ratio for Amaryl/Mepiril were log 0.9583-log 1.1357 and log 1.0570-log 1.2376, respectively. These values were within the acceptable bioequivalence intervals of log 0.80-log 1.25. Taken together, our study demonstrated the bioequivalence of Amaryl and Mepiril with respect to the rate and extent of absorption.

• Journal of Pharmaceutical Investigation
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• v.35 no.5
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• pp.355-360
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• 2005

The purpose of the present study was to evaluate the bioequivalence of two cetirizine HCl tablets, Zyrtec tablet (UCB Pharm. Co., Ltd. Korea, reference product) and Zyrix tablet (Kukje Pharm. Co., Ltd., Korea, test product), according to the guidelines of Korea Food and Drug Administration (KFDA). After adding an internal standard (diazepam), plasma samples were extracted using 1 mL of dichloromethane. Compounds extracted were analyzed by reverse-phase HPLC with ultra-violet detector. This method for determination cetirizine is proved accurate and reproducible with a limit of quantitation of 10 ng/mL in male plasma. Twenty-four healthy male Korean volunteers received each medicine at the cetirizine HCl dose of 10 mg in a $2{\times}2$ crossover study. There was a one-week wash out period between the doses. Plasma concentrations of cetirizine were monitored for over a period of 24 hr after the administration. AUC (the area under the plasma concentration-time curve) was calculated by the linear trapezoidal rule. $C_{max}$ (maximum plasma drug concentration) and $T_{max}$ (time to reach $C_{max}$) were compiled from the plasma concentration-time data. Analysis of variance was carried out using logarithmically transformed AUC and $C_{max}$. No significant sequence effect was found for all of the bioavailability parameters indicating that the crossover design was properly performed. The 90% confidence intervals for the log transformed data were acceptable range of log 0.8 to log 1.25 $(e.g.,\;log\;0.93-log\;1.08\;for\;AUC_{0-t},\;log\;0.91-log\;1.08\;for\;AUC_{0-{\infty}}\;and\;log\;1.01-log\;1.11\;for\;C_{max})$. The major parameters, AUC and $C_{max}$ met the criteria of KFDA for bioequivalence indicating that Zyrix tablet is bioequivalent to Zyrtec tablet.