• Title/Summary/Keyword: cross-resistance

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Livelihood Strategies of Ethnic Minority in the Borderlands: Case Study of the Bru-Van Kieu in Northern Central Vietnam (국경지역 소수민족의 생존전략: 베트남 중부의 브루반큐 민족을 사례로)

  • Nguyen, Trinh Minh Anh;Kim, Doo-Chul;Ubukata, Fumikazu
    • Journal of the Economic Geographical Society of Korea
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    • v.18 no.3
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    • pp.296-318
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    • 2015
  • The Bru-Van Kieu, one of ethnic minorities in Vietnam, have lived in the mountainous area along the border with Laos for centuries. Approximately by the end of the Second Indochina War, the Bru-Van Kieu were still a kinship-based and non-stratified societal group relying mainly on subsistence economy. Their traditional physical geography, nonetheless, has been transformed vigorously during the last few decades as a result of state-formation processes and changes in macro-economic policies. The paper aims to examine how ethnic minority adapt their livelihood to challenges instigated by macro political and economic processes. By examining livelihood adaptation of the Bru-Van Kieu, the study also identifies strategies that ethnic minorities use to negotiate with more powerful political and economic forces. The authors argue that the Bru-Van Kieu have deployed a strategy combining everyday resistance to maintain their limited social and cultural agencies and utilizing of these agencies in economic adaptation with other cross-ethnic non-state actors, enabling them to tap into new type of resources and opportunities.

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Establishment of Baseline Sensitivity of Phytophthora capsici Causing Pepper Phytophthora Blight to Carboxylic Acid Amide Fungicides (Carboxylic acid amide계 살균제에 대한 고추 역병균 Phytophthora capsici의 감수성 기준 설정)

  • Kim, Jin-Ho;Kim, Joo-Hyung;Lee, Kyeong-Hee;Rho, Chang-Woo;Kim, Heung-Tae
    • The Korean Journal of Pesticide Science
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    • v.14 no.4
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    • pp.456-462
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    • 2010
  • Baseline sensitivity to benthiavalicarb, iprovalicarb and dimethomorph included into carboxylic acid amide (CAA) group was evaluated in 180 isolates of Phytophthora capsici over 4 years from 2005 to 2008. $EC_{50}$ (effective concentration inhibiting mycelial growth by 50%) value of benthiavalicarb ranged from $0.015{\mu}g\;mL^{-1}$ to $0.049{\mu}g\;mL^{-1}$ with a mean of $0.033{\mu}g\;mL^{-1}$. The mean values of $EC_{50}$ of iprovalicarb and dimethomorph were 0.411 (0.197 - 0.556) ${\mu}g\;mL^{-1}$ and 0.271 (0.101 - 0.798) ${\mu}g\;mL^{-1}$, respectively. Although there was no increasing tendency in $EC_{50}$of benthiavalicarb and iprovalicarb during 4 years, $EC_{50}$ of dimethomorph was increased gradually by laps of time. There was no cross-resistance between each fungicide used in this study and metalaxyl. Among fungicides included into CAA group, there was a positive correlation between benthiavalicarb and iprovalicarb, and between dimethomorp and mandipropamid.

The association between measurement sites of visceral adipose tissue and cardiovascular risk factors after caloric restriction in obese Korean women

  • Lee, Hye-Ok;Yim, Jung-Eun;Lee, Jeong-Sook;Kim, Young-Seol;Choue, Ryowon
    • Nutrition Research and Practice
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    • v.7 no.1
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    • pp.43-48
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    • 2013
  • Quantities as well as distributions of adipose tissue (AT) are significantly related to cardiovascular disease (CVD) risk factors and can be altered with caloric restriction. This study investigated which cross-sectional slice location of AT is most strongly correlated with changes in CVD risk factors after caloric restriction in obese Korean women. Thirty-three obese pre-menopausal Korean women ($32.4{\pm}8.5$ yrs, BMI $27.1{\pm}2.3\;kg/m^2$) participated in a 12 weeks caloric restriction program. Subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) were measured using computed tomography (CT) scans at the sites of L2-L3, L3-L4, and L4-L5. Fasting serum levels of glucose, insulin, triglyceride, total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), leptin and homeostasis model assessment-insulin resistance (HOMA-IR) were observed. Pearson's partial correlation coefficients were used to assess the relationship between AT measurement sites and changes in CVD risk factors after calorie restriction. When calories were reduced by 350 kcal/day for 12 weeks, body weight (-2.7%), body fat mass (-8.2%), and waist circumference (-5.8%) all decreased (P < 0.05). In addition, following caloric restriction, serum levels of glucose (-4.6%), TC (-6.2%), LDL-C (-5.3%), leptin (-17.6%) and HOMA-IR (-18.2%) decreased significantly (P < 0.05) as well. Changes in VAT at the level of L3-L4 were significantly greater than those at other abdominal sites, and these changes were correlated with changes in TC (P < 0.05), LDL-C (P < 0.001), SBP (P < 0.001) and HOMA-IR (P < 0.01). These results show that VAT at L3-L4 had a stronger correlation with CVD risk factors than with other AT measurement sites after caloric restriction.

Overview of Zirconium Production and Recycling Technology (지르코늄의 제조(製造)와 재활용기술(再活用技術))

  • Park, Kyoung-Tae;Kim, Seung-Hyun;Hong, Soon-Ik;Choi, Mi-Sun;Cho, Nam-Chan;Yoo, Hwan-Jun;Lee, Jong-Hyeon
    • Resources Recycling
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    • v.21 no.5
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    • pp.18-30
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    • 2012
  • Zirconium is one of the most important material used as cladding of fuel rods in nuclear reactors because of its high dimensional stability, good corrosion resistance and especially low neutron-absorbing cross section. However, Hf free nuclear grade Zr sponge is commercially produced by only three countries including USA, France and Russia. So, Zr has been thoroughly managed as a national strategic material in Korea. Most of the zirconium is used for Korean nuclear industry as nuclear fuel cladding materials manufactured from Hf free Zr alloy raw material. Also, there are some other applications such as alloying element and detonator. In this review, zirconium production and recycling technologies have been reviewed and current industrial status was also analyzed. And recent achievements in innovative reduction technologies such as electrolytic reduction process and molten oxide electrolysis were also introduced.

Property and Microstructure Evolution of Nickel Silicides on Nano-thick Polycrystalline Silicon Substrates (나노급 다결정 실리콘 기판 위에 형성된 니켈실리사이드의 물성과 미세구조)

  • Kim, Jong-Ryul;Choi, Young-Youn;Song, Oh-Sung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.9 no.1
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    • pp.16-22
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    • 2008
  • We fabricated thermally-evaporated 10 nm-Ni/30 nm and 70 nm Poly-Si/200 nm-$SiO_2/Si$ structures to investigate the thermal stability of nickel silicides formed by rapid thermal annealing(RTA) of the temperature of $300{\sim}1100^{\circ}C$ for 40 seconds. We employed for a four-point tester, field emission scanning electron microscope(FE-SEM), transmission electron microscope(TEM), high resolution X-ray diffraction(HRIXRD), and scanning probe microscope(SPM) in order to examine the sheet resistance, in-plane microstructure, cross-sectional microstructure evolution, phase transformation, and surface roughness, respectively. The silicide on 30 nm polysilicon substrate was stable at temperature up to $900^{\circ}C$, while the one on 70 nm substrate showed the conventional $NiSi_2$ transformation temperature of $700^{\circ}C$. The HRXRD result also supported the existence of NiSi-phase up to $900^{\circ}C$ for the Ni silicide on the 30 nm polysilicon substrate. FE-SEM and TEM confirmed that 40 nm thick uniform silicide layer and island-like agglomerated silicide phase of $1{\mu}m$ pitch without residual polysilicon were formed on 30 nm polysilicon substrate at $700^{\circ}C\;and\;1000^{\circ}C$, respectively. All silicides were nonuniform and formed on top of the residual polysilicon for 70 nm polysilicon substrates. Through SPM analysis, we confirmed the surface roughness was below 17 nm, which implied the advantage on FUSI gate of CMOS process. Our results imply that we may tune the thermal stability of nickel monosilicide by reducing the height of polysilicon gate.

Estimation of Dynamic Displacement and Characteristics of A Simple Beam from FBG Sensor Signals (FBG센서 응답을 이용한 단순보의 동적 변위 및 동특성 추정)

  • Choi, Eun Soo;Kang, Dong Hoon;Chung, Won Seok;Kim, Hak Soo
    • Journal of Korean Society of Steel Construction
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    • v.18 no.4
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    • pp.503-514
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    • 2006
  • FBG sensors are capable of measuring the strain of structures easily and more durably than electric resistance gauges. Thus, many researches are dedicated to the application for the response monitoring or non-destructive evaluation of structures using FBG sensors. Additionally, the measured strains at the top and bottom of a cross-section can be transformed into the curvature of the section, which can be used to calculate its vertical displacement. Hence, this study aims to measure the dynamic strain signals of a steel section simply supported beam and to estimate the dynamic displacement from the strain signals, after which the estimated displacement is com pared with the measured displacement. The dynamic characteristics (natural frequency, damping ratio and mode shape) of the beam are predicted from both the estimated and measured displacement signals, and from the strain time history of the FBG sensors. The predicted properties are compared with those of an analytical model of the beam. The estimated displacement. However, the predicted dynamic properties from both the estimated displacements and the measured strains are well-correlated with those from the measured displacement. It is therefore appreciated that the estimation of the dynamic properties of FBG sensor signals is reasonable. Especially, the strain signal of the FBG sensor was amplified at a higher-frequency region in comparison with the displacement estimation with higher-mode properties.

Applications of Nanomanipulator in Nanowires (나노메니퓰레이터를 이용한 나노선의 특성평가)

  • Yoon, Sang-Won;Seo, Jong-Hyun;Ahn, Jae-Pyoung;Seong, Tae-Yeon;Lee, Kon-Bae
    • Journal of Powder Materials
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    • v.16 no.2
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    • pp.138-145
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    • 2009
  • The combination of focused ion beam (FIB) and 4 point probe nanomanipulator could make various nano manufacturing and electrical measurements possible. In this study, we manufactured individual ZnO nanowire devices and measured those electrical properties. In addition, tensile experiments of metallic Au and Pd nanowires was performed by the same directional alignment of two nanomanipulators and a nanowire. It was confirmed from I-V curves that Ohmic contact is formed between electrodes and nanomanipulators, which is able to directly measure the electrical properties of a nanowire itself. In the mechanical tensile test, Au and Pd nanowires showed a totally different fracture behavior except the realignment from <110> to <002>. The deformation until the fracture was governed by twin for Au and by slip for Pd nanowires, respectively. The crystallographic relationship and fracture mechanism was discussed by TEM observations.

Selection signature reveals genes associated with susceptibility loci affecting respiratory disease due to pleiotropic and hitchhiking effect in Chinese indigenous pigs

  • Xu, Zhong;Sun, Hao;Zhang, Zhe;Zhang, Cheng-Yue;Zhao, Qing-bo;Xiao, Qian;Olasege, Babatunde Shittu;Ma, Pei-Pei;Zhang, Xiang-Zhe;Wang, Qi-Shan;Pan, Yu-Chun
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.2
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    • pp.187-196
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    • 2020
  • Objective: Porcine respiratory disease is one of the most important health problems causing significant economic losses. To understand the genetic basis for susceptibility to swine enzootic pneumonia (EP) in pigs, we detected 102,809 single nucleotide polymorphisms in a total of 249 individuals based on genome-wide sequencing data. Methods: Genome comparison of susceptibility to swine EP in three pig breeds (Jinhua, Erhualian, and Meishan) with two western lines that are considered more resistant (Duroc and Landrace) using cross-population extended haplotype homozygosity and F-statistic (FST) statistical approaches identified 691 positively selected genes. Based on quantitative trait loci, gene ontology terms and literature search, we selected 14 candidate genes that have convincible biological functions associated with swine EP or human asthma. Results: Most of these genes were tested by several methods including transcription analysis and candidate genes association study. Among these genes: cytochrome P450 1A1 and catenin beta 1 (CTNNB1) are involved in fertility; transforming growth factor beta receptor 3 plays a role in meat quality traits; Wnt family member 2, CTNNB1 and transcription factor 7 take part in adipogenesis and fat deposition simultaneously; plasminogen activator, urokinase receptor (completely linked to AXL receptor tyrosine kinase, r2 = 1) plays an essential role in the successful ovulation of matured oocytes in pigs; colipase like 2 (strongly linked to SAM pointed domain containing ETS transcription factor, r2 = 0.848) is involved in male fertility. Conclusion: These adverse genes susceptible to swine EP may be selected while selecting for economic traits (especially reproduction traits) due to pleiotropic and hitchhiking effect of linked genes. Our study provided a completely new point of view to understand the genetic basis for susceptibility or resistance to swine EP in pigs thereby, provides insight for designing sustainable breed selection programs. Finally, the candidate genes are crucial due to their potential roles in respiratory diseases in a large number of species, including human.

Human Neutrophil Cathepsin G: In Vivo Synthesis of Anti-HNCG Antibody, Inhibition of the Activity of HNCGs and Mechanism of the Inhibitions (사람 호중구 Cathepsin G: Anti-HNCG Ab의 In Vivo 합성, HNCG의 활성도 억제와 그 기전에 관한 연구)

  • Bae, Sung-Jun;Kim, Woo-Mi;Kim, Ki-Chan;Chang, Myung-Woong;Kang, Koo-Il
    • The Korean Journal of Pharmacology
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    • v.27 no.2
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    • pp.145-153
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    • 1991
  • Human neutrophil cathepsin-G, which has been known as one of the active enzymes causing inflammatory diseases, was purified by two steps procedure involving one size exclusion (Ultorogel AcA54) and one ion exchange (CM-Sephadex) chromatography. Purified HNCGs were cross-reacted with Anti-HNCathepsin-G antibodies which were radised in rabbits and purified by cathepsin-G labeled Sepharose 4B affinity chromatography. HNCGs were effectively inhibited by NSAIDs including phenylbutazone, sulindac, oxyphenbutazone, salicylic acid and salicyluric acid. $IC_{50}_s$ of these drugs for inhibition of Cathepsin G were 0.3-0.8 mM. Other NSAIDs including aspirin showed little or no inhibition effect on the activity of Cathepsin G. These results strongly indicated that NSAIDs which showed inhibition effect on the activity of HNCGs possibly be at least a part of mechanism of action which might be related to direct inhibition of cathepsin G at the tissue destruction sites beside of their known mechanism of action as an anticyclo-oxygenase in treatment of inflammatory diseases. Lipid soluble component of Korean Red Ginseng which was known as an anti-inflammatory agent inhibited HNCGs strongly, but no other fractions did inhibited HNCGs. Antibiotics including novobiosin and rifamycin showed some inhibition effect on HNCGs, i. e.., $IC_{50}$ of these drugs were 2.6 mM and 1.5 mM respectively, and other antibiotics including penicillin G showed no or negligible inhibition effect on the activity of HNCGs. However. tetracyclines inhibited HNCGs very effectively at the concentration of therapeutic range. The inhibition effect of the activity of HNCGs by tetracycline are not related to the N-dimethyl radical on the 4 position of the tetracycline molecule. Furthermore, N-dedimethylated tetracyclines may have beneficial effect for long term treatment of chronic inflammatory diseases without developing any drug resistance to microorganisms.

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An Experimental Study on Flexural Behavior of Steel Fiber Reinforced Ultra High Performance Concrete Prestressed Girders (강섬유 보강 초고성능 콘크리트 프리스트레스트 거더의 휨거동 실험 연구)

  • Yang, In-Hwan;Joh, Chang-Bin;Kim, Byung-Suk
    • Journal of the Korea Concrete Institute
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    • v.22 no.6
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    • pp.777-786
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    • 2010
  • This paper examines the flexural behavior of full-scale prestressed concrete girders that were constructed of steel fiber reinforced ultra high performance concrete (UHPC). This study is designed to provide more information about the bending characteristics of UHPC girders in order to establish a reasonable prediction model for flexural resistance and deflection for future structural design codes. Short steel fibers have been introduced into prestressed concrete T-girders in order to study their effects under flexural loads. Round straight high strength steel fibers were used at volume fraction of 2%. The girders were cast using 150~190 MPa steel fiber reinforced UHPC and were designed to assess the ability of steel fiber reinforced UHPC to carry flexural loads in prestressed girders. The experimental results show that steel fiber reinforced UHPC enhances the cracking behavior and ductility of beams. Moreover, when ultimate failure did occur, the failure of girders composed of steel fiber reinforced UHPC was observed to be precipitated by the pullout of steel fibers that were bridging tension cracks in the concrete. Flexural failure of girders occurred when the UHPC at a particular cross section began to lose tensile capacity due to steel fiber pullout. In addition, it was determined that the level of prestressing force influenced the ultimate load capacity.