• Current Optics and Photonics
• /
• v.1 no.1
• /
• pp.17-22
• /
• 2017

Mechanical property of tissue is closely related to diseases such as breast cancer, prostate cancer, cirrhosis of the liver, and atherosclerosis. Therefore measurement of tissue mechanical property is important for a better diagnosis. Ultrasound elastography has been developed as a diagnostic modality for a number of diseases that maps mechanical property of tissue. Optical coherence elastography (OCE) has a higher spatial resolution than ultrasound elastography. OCE, therefore, could be a great help for early diagnosis. In this study, we made tissue phantoms and measured their compressive moduli with a rheometer measuring the response to applied force. Uniaxial strain of the tissue phantom was also measured with OCE by using cross-correlation of speckles and compared with the results from the rheometer. In order to compare stiffness of tissue phantoms by OCE, the applied force should be measured in addition to the strain. We, however, did not use a load cell that directly measures the applied force for each sample. Instead, we utilized one silicone film (called as reference phantom) for all OCE measurements that indirectly indicated the amount of the applied force by deformation. Therefore, all measurements were based on displacement, which was natural and effective for image-based elastography such as OCE.

• Journal of the Optical Society of Korea
• /
• v.12 no.2
• /
• pp.103-106
• /
• 2008

It is shown that the two mode representations, one with vector modes and the other with scalar modes, for the cross spectral density matrices of electromagnetic beams are equivalent to each other. In particular, we suggest a method to find the vector modes from the scalar modes and formulate the cross spectral density matrix as a correlation matrix.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.43 no.3
• /
• pp.247-254
• /
• 2017

Optical Coherence Tomography (OCT) is a non-invasive imaging method that utilizes the optical scattering and interference for visualizing the surface as well as cross-sectional structures of tissue. OCT has been used for diagnosing diseases in early stage in various medical fields, but an application in cosmetics is still at early stage. In this study, OCT was adopted to evaluate skin texture and wrinkle. Results showed similar patterns of evaluation with PRIMOS in the assessment using replica. In addition, OCT produced smaller errors at different angles compared to the PRIMOS in the assessment using 3-dimensional models of wrinkles. The resolution of the image was also high enough to differentiate the images of before and after the application of makeup products. Possible use of OCT in the evaluation of fine wrinkle assessment was studied in this research. Further development of methods is necessary to provide more evidences of the effectiveness.

• Proceedings of the Korean Society of Precision Engineering Conference
• /
• 2011.06a
• /
• pp.829-830
• /
• 2011

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.18 no.5
• /
• pp.126-131
• /
• 2004

As a noninvasive imaging method, optical coherence tomography system has been extensively studied because it has some advantages such as imaging of high resolution, low cost, and compact size configuration. In order to improve the SNR of OCT system, two types of interferometers were configured and then, we compared simulation with measurement of reference sample. In the OCT system is configured with Michelson interferometer, the contrast of cross-sectional image is reduced with low SNR detection which is due to loss of feedback interference signal from light source part. Also, in order to image measured data with real time, image processing program is constructed. From results of simulation, it is confirmed that improved Michelson interferometer is improved about 10[dB] with a 50 : 50 fiber coupler. And from the measurement of reference sample, about 5[dB] is improved with a 50 : 50 fiber coupler. It is confirmed that the OCT system is configured with the improved Michelson interferometer which has a good distinctive cross-sectional image due to higher contrast.

• Water for future
• /
• v.14 no.4
• /
• pp.19-26
• /
• 1981

The auto-and cross-correlation function, power spectrum, coherence function and Markov model are applied to investigate the statistical characteristics of discharge and each factor of water quality and the interrelation-ship between the variation of discharge and water quality factors. The analysis of discharge, dissolved oxygen and electric conductivity, which were only obtainable data at the Indogyo gagining station in the downstream of the Han River, clearly showed that they hace distinct period of 12 months and three different periods of 6, 4 and 3 months weaker than the former. The cross-correlation between the discharge and water quality(DO, COND) is rather weak and the crosscorrelation function has its peak at lag one. It is considered therefrom that the variation of discharge behaves on water quality facotrs with one day's difference. In the examination of linear regression model for the serial generation and predictive measures, discharge series is fit to first and second order Markov model and DO, COND to first order Markov model.

• Journal of the Optical Society of Korea
• /
• v.15 no.4
• /
• pp.380-385
• /
• 2011

Common-path interferometers are widely used for endoscopic optical coherence tomography (OCT) because an arbitrary arm length can be chosen for the endoscopic imaging probe. However, the scheme suffers from the limited range of the sample position distance from the end of the imaging probe because the position between the reference reflector and the sample is limited by the optical path-length difference (OPD) to induce an interference signal. In this study, we developed a novel method for compensating the arbitrary sample position in common-path swept-source OCT by adding an extra Mach-Zehnder interferometer in the post-path of the interfered optical signal. Theoretical analysis and an experimental demonstration of imaging depth tuning for the flexible sample position of an endoscopic OCT image are discussed. After post-tuning of sample position distance, the positioning limitation between the reference reflector and the sample can be solved for various sample positions over a range of 26 mm for the cross-sectional images of a fish eye sample.

• Journal of the Korean Data and Information Science Society
• /
• v.25 no.4
• /
• pp.807-817
• /
• 2014

This paper considers multivariate time series modelling of PM10 data in Korea collected from 2008 to 2011. We consider both temporal and spatial dependencies of PM10 by applying the sparse vector autoregressive (sVAR) modelling proposed by Davis et al. (2013). It utilizes the partial spectral coherence to measure cross correlation between different regions, in turn provides the sparsity in the model while balancing the parsimony of model and the goodness of fit. It is also shown that sVAR performs better than usual vector autoregressive model (VAR) in forecasting.

• Transactions of the Society of Information Storage Systems
• /
• v.9 no.1
• /
• pp.17-21
• /
• 2013

Optical coherence tomography (OCT) allows non-invasive, cross-sectional optical imaging of biological tissue with high spatial resolution and acquisition speed. In principle, it is analogous to ultrasound imaging, but uses near-infrared light instead of ultrasound, measuring the time-delay of back-scattered light from within biological tissue. Compared to ultrasound imaging, it exhibits superior spatial resolution (1~10 um) and high sensitivity. Therefore, OCT has been applied to a wide range of applications such as cellular imaging, ophthalmology and cardiology. Here, we describe a novel application of OCT technology in visualizing microneedles embedded in tissue that is developed to deliver drugs into the dermis without the injection mark in the human skin. Detailed three-dimensional structural images of microneedles and biological tissues were obtained. Examining structural modification of microneedles and tissues during insertion process would enable to evaluate performance of various types of microneedles in situ.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
• /
• v.18 no.6
• /
• pp.31-36
• /
• 2004

Optical coherence tomography system has been extensively studied because it has some advantages such as imaging of high resolution, low cost, and compact size configuration. In order to obtain high resolution of OCT system we configured OCT system using a femto-second laser. We measure the pulse width using autocorrelator function because a femto-second laser is ultra short pulse. And we measured the practical resolution using theoretical equation and the measurement of reference sample. It is confirmed that the proposed OCT system has 1.5 times higher resolution and un distinctive cross-sectional image than OCT system with SLD as a light source.