• 산업공학
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• 제15권1호
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• pp.26-39
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• 2002

Two key data areas of the integrated production database in computer-integrated manufacturing (CIM) systems are the product structure in the forms of bills of material(BOM) and the process structure in the forms of routings. The great majority of existing information systems regard the BOM and routing as two separate data entities, possibly with some degree of cross-referencing. This paper proposes new information structure called the bills of material and routings(BMR) that logically integrates the BOM and routings for the CIM systems in ship production. The characteristics of ship production are described as: 1) make-to-order production type, 2) combined manufacturing principles (workshop production and construction site production), 3) significant overlapping of design, planning and manufacturing, 4) very long order throughput time, 5) complex product structure and production process. The proposed BMR systematically manages ail parts and operations data needed ship production considering characteristics of ship production. Also, the BMR situated on the integrated production database more efficiently supports interface between engineering and production functions, and integrates a wide variety of functions within production such as production planning, process planning, operation scheduling, material planning, costing etc., and simplifies information flow between sub-systems in CIM systems.

• 약학회지
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• 제48권6호
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• pp.379-383
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• 2004

Biphenyl dimethyl dicarboxylate (DDB) has been used for the treatment of chronic viral hepatitis B and drug-induced hepatitis through the inhibition of lipid peroxidation and c ovalent binding of drug metabolites to lipids of microsomes. The bioequivalence of two DDB products was evaluated according to the guidelines of KFDA. The test product was Hepaphil soft capsule(R) made by KMS Pharm. Co. Containing 3 mg DDB and the reference product was Nissel tablet(R) made by Taerim Pharm. Co. Containing 25 mg DDB. Twenty healthy male subjects, 25.4(22~30) years old and 66.7(54~77)kg, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After two tablets or two capsules were orally administered, blood was taken at predetermined time intervals and the concentration of DDB in plasma was determined using a validated HPLC method with UV detector. Two pharmacokinetic parameters, $AUC_t$ and $C_{max}$, were calculated and analyzed statistically for the evaluation of bioequivalence of the two products. Analysis of variance was carried out using logarithmically transformed parameter values. The 90% confidence intervals of $AUC_t$ and $C_{max}$ were log 0.91~log1.00 and log 1.05~log 1.15, respectively. These values were within the acceptable bioequivalence intervals of log 0.8 to log 1.25. Thus, the criteria of the KFDA guidelines for the bioequivalence was satisfied, indicating that Hepaphil soft capsule is bioequivalent to Nissel tablet.

• 농촌지도와개발
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• 제16권1호
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• pp.99-124
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• 2009

The purposes of this study were (1) to highlight the importance of farm management (2) to develop a profitable farm management system through the combination of agricultural techniques and business competencies (3) to shift management attitudes and habits of the program participants from being passive and dependent toward being proactive and self-disciplined (4) to help cultivate one's own life through self-consciousness participation in educational activities and lectures of celebrities. This research was conducted involving 30 farms that participated in the business program. The program imparted knowledge on vision, marketing, business skills, and management strategies such as cross strengths, weaknesses, opportunities, threats (swot) analysis, product life cycle (plc), the 4p(product, price, place, promotion) of marketing, etc. The study recommends: (1) to encourage farms to enhance their business competencies; (2) to find out solutions for urgent management problems (3) to construct a system for leading farms (www.lfcenter.com) and on-line communities and (4) to implement a profitable business model for leading farms. It was noted that the farms were eager to participate in such business programs. In the future, this kind of program should be promoted in other areas so that more farms could enhance their business competencies.

• Fibers and Polymers
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• 제2권4호
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• pp.203-211
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• 2001

Residual stresses were predicted by a flow analysis in the mold cavity and residual stress distribution in the injection molded product was measured. Flow field was analyzed by the hybrid FEM/FDM method, using the Hele Shaw approximation. The Modified Cross model was used to determine the dependence of the viscosity on the temperature and the shear rate. The specific volume of the polymer melt which varies with the pressure and temperature fields was calculated by the Tait\`s state equation. Flow analysis results such as pressure, temperature, and the location of the liquid-solid interface were used as the input of the stress analysis. In order to calculate more accurate gap-wise temperature field, a coordinate transformation technique was used. The residual stress distribution in the gap-wise temperature field, a coordinate transformation technique was used. The residual stress distribution in the gap-wise direction was predicted in two cases, the free quenching, under the assumption that the shrinkage of the injection molded product occurs within the mold cavity and that the solid polymer is elastic. Effects of the initial flow rate, packing pressure, and mold temperature on the residual stress distribution was discussed. Experimental results were also obtained by the layer removal method for molded polypropylene.

• 품질경영학회지
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• 제30권1호
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• pp.1-21
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• 2002

The purpose of this study was to empirically examine the customer oriented quality creation by considering quality elements required by customers in the product design process. The study tried to extract attractive quality elements by using Kano's model. After identifying the elements HOQ(the house of quality) of QFD(quality function deployment) was used to identify the trend of quality elements evaluation. Test for equal means (t-test) was applied to verify the attractive quality elements of adult shoes. It made us find the customer oriented quality elements from the customer needs and latent dissatisfaction. We collected the opinions of experts on shoes and complete the cause and effect diagram and affinity diagram (KJ method). The data of the questionnaire was put to the QFD and the contents of quality elements was identified by brain storming method. We calculated indexes which were the multiplication of weight and marks of quality elements in the cross table of the HOQ by QFD. Then we tested for the equality of means between the indexes and the sum of attractive quality elements. The results for equal means were statistically significant. To create the customer quality the product design should be differentiated between the age groups over attractive quality elements.

• Bulletin of the Korean Chemical Society
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• 제32권12호
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• pp.4210-4214
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• 2011

Quasiclassical trajectory (QCT) calculations of Ne + ${H_2}^+$ reaction have been carried out on the adiabatic potential energy surface of the ground state $1^2$ A'. The reaction probability of the title reaction for J = 0 has been calculated, and the QCT result is consistent with the previous quantum mechanical wave packet result. Quasiclassical trajectory calculations of the four polarization-dependent differential cross sections have been carried out in the center of mass (CM) frame. The P(${\theta}_r$), P(${\phi}_r$) and P(${\theta}_r$, ${\phi}_r$) distributions, the k-k'-j' correlation and the angular distribution of product rotational vectors are presented in the form of polar plots. Due to the well in $1^2$ A' PES, the reagent vibrational excitation has greater influence on the polarization of the product rotational angular momentum vectors j' than the collision energy.

• 소성∙가공
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• 제26권1호
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• pp.28-34
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• 2017

Multi-pass shape rolling is performed to produce long products of arbitrary cross-sectional shapes. In the past, the multi-pass shape rolling process has been designed by the trial and error method or the experience of experts based on the empirical approach. Particularly, the design of roll caliber in shape rolling is important to improve product quality and dimensional accuracy. In this paper, the caliber design and pass schedule of multi-pass shape rolling were proposed for manufacturing piston ring wire. In order to design roll caliber, major shape parameter and dimension was determined by analysis of various caliber design. FE-simulation was conducted to verify effectiveness of proposed process design. At first, forming simulation was performed to predict shape of the product. Then, fracture of the wire was evaluated by critical damage value using normalized Cockcroft-Latham criteria. The experiment was carried out and the results are within the allowable tolerance.

• 한국정밀공학회지
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• 제24권4호
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• pp.102-108
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• 2007

The characteristic properties of aluminum, high strength stiffness to weight ratio, good formability, good corrosion resistence, and recycling potential make it the ideal candidate to replace heavier materials in the car to respond to the weight reduction demand within the automotive industry. In this paper, FE simulation was carried out to design an appropriate extrusion die for the automobile control arm. Based on the FE simulation result, a new die design has been proposed for uniform material flow in the cross section of extruded product. And then the welding pressure, extrusion load, and the tendency of mandrel deflection were estimated to verify high quality. In the extrusion experiment, it was possible to produce sound product without defects.

• Bulletin of the Korean Chemical Society
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• 제34권10호
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• pp.3046-3054
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• 2013

Synthesis of Carbon Nanotube bundles has been achieved by simple and economical solvothermal procedure at very low temperature of $180^{\circ}C$. The product yield obtained was about 70-75%. The optimization of reaction conditions for an efficient synthesis of CNTs has been presented. The CNTs are obtained by reduction of hexachlorobenzene in the presence of Na/Ni in cyclohexane. The X-ray diffraction, Fourier transform infrared and Raman spectral studies have inferred us the graphene structure of the products. The CNTs formed as the bundles were viewed on scanning electron microscope, transmission electron microscope and high-resolution transmission electron microscope. These are the multiwalled CNTs with outer diameter of 5-10 nm, the inner diameter 2-4 nm and cross sectional diameter up to 5 nm. Brunauer-Emmett-Teller (BET) based $N_2$ gas adsorption studies have been made to obtain BET surface area and $H_2$ storage capacity. Effect of the experimental variables such as reaction temperature, amount of catalyst and the amount of carbon source were investigated. It is found that they affect significantly on the product nature and yield.

• 미생물학회지
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• 제28권1호
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• pp.6-12
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• 1990

adr 아형 B형 간염바이러스의 preS2염기서열을 베타갈락토시다세 유전자에 연결시켜 클론닝한 후, 융합단백질의 형태로 대장균에서 발현시켰다. 한국인 간염환자로부터 분리된 표면항원으로 유도한 단일 클론항체 H8는 preS2에 특이성을 지니고 있으며, 상기의 융합단백질과 특이적으로결합하였다. 이 단일 클론항체는 adw2아형 preS2 융합단백질과는 단지 낮은 수준의 결합성을 보여주었는데, 이와 같은 단일클론항체 H8의 adr 아형과 adw2아형에 대한 결합성의 차이는 preS2부위의 아미노산 차이에 기인한다고볼 수 있다.