• Title/Summary/Keyword: critical region

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Clinical Assessment of Intracranial Mesenchymal Tumors with Relevant to Non-meningothelial Tumors (두개강내 원발성 간엽성 종양에 대한 임상 고찰)

  • Yi, Hyeong Joong;Kim, Choong Hyun;Bak, Koang Hum;Kim, Young Soo;Kim, Jae Min;Ko, Yong;Oh, Suck Jun;Kim, Kwang Myung
    • Journal of Korean Neurosurgical Society
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    • v.29 no.1
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    • pp.44-50
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    • 2000
  • Objective : A few anecdotal cases of mesenchyme-derived tumors which grow into a cranial cavity have been reported that disclosed a dismal prognosis, due to their critical location, aggressive biological behavior, and high rate of surgical morbidity. The aim of this study is to search clinical factors related to these tumors. Methods : Eight patients who underwent surgical removal of intracranial mesenchymal tumors between January 1993 and December 1997 were studied retrospectively. The tumors included are three chordomas, two chondrosarcomas, two rhabdomyosarcomas, and one hemangiopericytoma. Authors compared clinical features, treatment, and results of our cases with reported cases. The mean follow-up period was 20.5 months. Results : All cases showed nonspecific, location-related clinical findings and arose from sphenopetroclival region. Single stage operation was performed in 4 cases, and skull base approaches in 3 cases. Adjuvant therapies were done in 2 cases. Recurrence was seen in 3 cases(37.5%), and 3 patients died. Interdisciplinary approach with otologic surgeon was done in 2 cases. Conclusion : Recent advancement of refined tactics has made these tumors amenable and provides prolongation of progression-free survival. These are modified skull base approaches, multi-modality treatment options, and inter-disciplinary team approaches. Good results may be expected for these mesenchymal tumors by aggressive resection and adjuvant therapies according to their biological nature.

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Finite Element Analysis and Experimental Verification for the Cold-drawing of a FCC-based High Entropy Alloy (FCC계 고엔트로피 합금의 냉간 인발 유한요소해석 및 실험적 검증)

  • Cho, H.S.;Bae, S.J.;Na, Y.S.;Kim, J.H.;Lee, D.G.;Lee, K.S.
    • Transactions of Materials Processing
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    • v.29 no.3
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    • pp.163-171
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    • 2020
  • We present a multi-step cold drawing for a non-equiatomic Co10Cr15Fe25Mn10Ni30V10 high entropy alloy (HEA) with a simple face-centered cubic (FCC) crystal structure. The distribution of strain in the cold-drawn Co10Cr15Fe25Mn10Ni30V10 HEA wires was analyzed by the finite element method (FEM). The effective strain was expected to be higher as it was closer to the surface of the wire. However, the reverse shear strain acted to cause a transition in the shear strain behavior. The critical effective strain at which the shear strain transition behavior is completely shifted was predicted to be 4.75. Severely cold-drawn Co10Cr15Fe25Mn10Ni30V10 HEA wires up to 96% of the maximum cross-sectional reduction ratio were successfully manufactured without breakage. With the assistance of electron back-scattering diffraction and transmission electron microscope analyses, the abundant deformation twins were found in the region of high effective strain, which is a major strengthening mechanism for the cold-drawn Co10Cr15Fe25Mn10Ni30V10 HEA wire.

Generic studies on thermo-solutal convection of mercurous chloride system of ${Hg_2}{Cl_2}$ and Ne during physical vapor transport

  • Choi, Jeong-Gil;Lee, Kyong-Hwan;Kim, Geug-Tae
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.19 no.1
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    • pp.39-47
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    • 2009
  • The effects of thermo-solutal convection on mercurous chloride system of ${Hg_2}{Cl_2}$, and Ne during physical vapor transport are numerically investigated for further understanding and insight into essence of transport phenomena, For $10\;K{\le}{\Delta}T{\le}30\;K$, the growth rate slowly increases and, then is decreased gradually until ${\Delta}T$=50 K, The occurrence of this critical point near at ${\Delta}T$=30 K is likely to be due to the effects of thermo-physical properties stronger than the temperature gradient corresponding to driving force for thermal convection. For the range of $10\;Torr{\le}P_B{\le}300\;Torr$, the rate is second order-exponentially decayed with partial pressures of component B, $P_B$. For the range of $5{\le}M_B{\le}200$, the rate is second order-exponentially decayed with a function of molecular weight of component B, $M_B$. Like the case of a partial pressure of component B, the effects of a molecular weight arc: reflected through the binary diffusivity coefficients, which are intimately related with suppressing the convection flow inside the growth enclosure, i,e., transition from convection to diffusion-dominant flow mode as the molecular weight of B increases. The convective mode is near at a ground level, i,e., on earth (1 $g_0$), and the convection is switched to the diffusion mode for $0.1\;g_0{\le}g{\le}10^{-2}g_0$, whereas the diffusion region ranges from $10^{-2}g_0$ up to $10^{-5}g_0$.

Mixing and Penetration Studies of Transverse Jet into a Supersonic Crossflow (초음속 유동 내 공동을 이용한 수직 분사 혼합 및 연료 침투거리에 관한 연구)

  • Kim, Chae-Hyoung;Jeong, Eun-Ju;Jeung, In-Seuck;Kang, Sang-Hun;Yang, Soo-Seok
    • Journal of the Korean Society of Propulsion Engineers
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    • v.12 no.2
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    • pp.24-32
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    • 2008
  • A non-reacting experimental study on a normal injection into a Mach 1.92 crossflow which flows over various geometries(flat plate, small cavity, large cavity) was carried out to investigate the effect of the momentum flux ratio(J). The aft ramp of the cavity advances the increase of the penetration height and the strong two-dimensional shock from recompression region mainly affects the shock structure and mixing layer at the downstream flow. As flow runs downward, the transverse penetration height increases with increasing J(J = 0.9, 1.7, 3.4). However, above some critical ratio, jet penetration height growth with increasing J is not appeared in flow-field. Large scale cavity has a good mixing efficiency but it increases the drag loss in the combustor.

The Evaluation of Ceiling Depth Impact on Lighting and Overall Energy Consumption of a Building with Top-lighting System

  • Amina, Irakoze;Kee, Han Ki;Lee, Young-A
    • Architectural research
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    • v.22 no.1
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    • pp.13-21
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    • 2020
  • The purpose of this study was to evaluate the variation in building energy predictions caused by simulation settings related to building envelop thickness. The study assessed the ceiling depth impact on skylight energy performance through OpenStudio integrated Radiance and EnergyPlus simulation programs. A ceiling as deep as 1.5 to 3m was analyzed for skylight to roof ratios from 1% to 25%. The results indicated that the building ceiling depth negatively affected the capability of skylights to significantly reduce building energy consumption. Through a parametric analysis, the study concluded that 8%, 9%, 10% and 11% skylight to roof ratio were optimal in terms of total building energy consumption for a ceiling depth of 1.5m, 2m, 2.5m and 3m, respectively. In addition, the results showed that the usually recommended 5% skylight to roof ratio was only efficient when no ceiling depth was included in the simulation model. Furthermore, the study indicated that the building energy saved by the optimal skylight of each ceiling depth decreased as the ceiling depth deepened. The highest total building energy reduction was 9%, 7%, 5% and 3% for a ceiling depth of 1.5m, 2m, 2.5m and 3m, respectively. This study induced that the solar heat gains and daylight visible transmittance by ceiling depth were crucial in the predictions of skylight energy performance and should not be neglected through building simulation simplifications as it is commonly done in most simulation programs' settings.

Evaluation of Plastic Rotational Capacity Based on Material Characteristics in Reinforced Concrete Flexural Members (재료 특성에 기반한 철근콘크리트 휨부재의 소성회전능력 산정)

  • Choi, Seung-Won;Kim, Woo
    • Journal of the Korea Concrete Institute
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    • v.22 no.6
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    • pp.825-832
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    • 2010
  • Although a critical section reaches its flexural strength in reinforced concrete structures, the structure does not always fail because moment redistribution occurs during the formation of plastic hinges. Inelastic deformation in a plastic hinge region results in plastic rotation. A plastic hinge mainly depends on material characteristics. In this study, a plastic hinge length and plastic rotation are evaluated using the flexural curvature distribution which is derived from the material models given in Eurocode 2. The influence on plastic capacity the limit values of the material model used, that is, ultimate strain of concrete and steel and hardening ratio of steel(k), are investigated. As results, it is appeared that a large ultimate strain of concrete and steel is resulting in large plastic capactiy and also as a hardening ratio of steel increases, the plastic rotation increases significantly. Therefore, a careful attention would be paid to determine the limit values of material characteristics in the RC structures.

Lateral Resisting Capacity for CFT Column to RC Flat Plate Slab Exterior Connections (CFT 기둥-RC 무량판 슬래브 외부접합부의 횡저항 성능)

  • Song, Ho-Beom;Song, Jin-Kyu;Oh, Sang-Won;Kim, Byung-Jo
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.11a
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    • pp.61-64
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    • 2008
  • A combination of CFT column and RC flat plate without formworks is very effectively rapid constructions. This paper verified the lateral resisting capacity of CFT column-RC flat plate exterior connection in comparison with general RC column-flat plate connection and detected moment capacity and ductility capacity of connection according to moment-displacement ratio. We made and tested specimens which have different variables respectively and as a result derive a following conclusion. In CFT-E2 specimen a critical section was extended and maximum moment increased 20% respectively in comparison to general RC column specimen. In BME and CFT-E1 specimens generally shear governed behaviors and CFT-E2 specimen complemented with seismic band, flexure behavior region of slab was extended and also ductility ratio and energy absorptance increased.

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Participation of NMDA and non-NMDA glutamate receptors in the formalin-induced inflammatory temporomandibular joint nociception

  • Yang, Gwi-Y.;Lee, Ju-H.;Ahn, Dong-K.
    • International Journal of Oral Biology
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    • v.32 no.2
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    • pp.59-65
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    • 2007
  • It has been well known that excitatory amino acids, primarily glutamate, are involved in the transmission of nociception in pathological and physiological conditions in the spinal and brainstem level. Recently, peripheral glutamate also play a critical role in the peripheral nociceptive transmissions. The present study investigated the role of N-methyl-D-aspartic acid (NMDA) or non-NMDA ionotropic glutamate receptors in formalin-induced TMJ pain. Experiments were carried out on male Sprague-Dawley rats weighing 220-280 g. Intra-articular injection was performed under halothane anesthesia. Under anesthesia, AP-7 (10, $100\;{\mu}M$, $1\;mM/20\;{\mu}L$), a NMDA receptor antagonist, or CNQX disodium salt (0.5, 5, 50, $500\;{\mu}M/20\;{\mu}L$), a non-NMDA receptor antagonist, were administered intra-articularly 10 min prior to the application of 5% formalin. For each animal, the number of behavioral responses, such as rubbing and/or scratching the TMJ region, was recorded for nine successive 5-min intervals. Intra-articular pretreatment with 1 mM of AP-7 or $50\;{\mu}M$ CNQX significantly decreased the formalin-induced scratching behavioral responses during the second phase. Intra-articular pretreatment with $500\;{\mu}M$ of CNQX significantly decreased the formalin-induced scratching behavior during both the first and the second phase. These results indicate that the intra-articular administration of NMDA or non-NMDA receptor antagonists inhibit formalin-induced TMJ nociception, and peripheral ionotropic glutamate receptors may play an important role in the TMJ nociception.

IEEE 802.15.4a based Localization Algorithm for Location Accuracy Enhancement in the NLOS Environment (실내 NLOS환경에서 정밀도 향상을 위한 IEEE 802.15.4a 기반의 위치추정 알고리즘)

  • Cha, Jae-Young;Kong, Young-Bae;Choi, Jeung-Won;Ko, Jong-Hwan;Kwon, Young-Goo
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.16 no.8
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    • pp.1789-1798
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    • 2012
  • IEEE 802.15.4a standard can provide a variety of location-based services for ZigBee or wireless network applications by adapting the time-of-arrival (TOA) ranging technique. The non-line-of-sight (NLOS) condition is the critical problem in the IEEE 802.15.4a networks, and it can significantly degrade the performance of the TOA-based localization. To enhance the location accuracy due to the NLOS problem, this paper proposes an energy-efficient low complexity localization algorithm. The proposed approach performs the ranging with the multicast method, which can reduce the message overhead due to packet exchanges. By limiting the search region for the location of the node, the proposed approach can enhance the location accuracy. Experimental results show that the proposed algorithm outperforms previous algorithms in terms of the energy consumption and the localization accuracy.

Phase Diagrams and Stable Structures of Stranski-Krastanov Structure Mode for III-V Ternary Quantum Dots

  • Nakaima, Kazuno;Ujihara, Toru;Miyashita, Satoru;Sazaki, Gen
    • Proceedings of the Korea Association of Crystal Growth Conference
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    • 1999.06a
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    • pp.81-114
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    • 1999
  • The strain, surface and inerfacial energies of III-V ternary systems were calculated for three kinds of structure modes: the Frank-van der Merwe (FM) mode, the Stranski-Krastanov (SK) mode an the Volmer-Wever (VW) mode. The free energy for each mode was estimated as functions of the thickness and composition or lattice misfit. Through comparison of the free energy of each mode, it was found that the thickness-composition phase diagrams of III-V ternary systems can be determined only by considering the balance of the free energy and three kinds of structure modes appear in the phase diagrams. The SK mode appears only when the lattice misfit is large and/or the lattice layer is thick. The most stable structure of the SK mode is a cluster with four lattice layers or minimum thickness on a wetting layer of increasing lattice layers. The VW mode appears when the lattice misfit is large and the lattice layer is thin and only in the InPSb/InP and GaPSb/GaP systems which have the largest lattice misfit of III-V ternary systems. The stable region of the SK mode in the GaPSb/GaP and InPSb/InP phase diagrams is largest of all because the composition dependence of the strain energy of these systems is stronger than that of the other systems. The critical number of lattice layers below which tow-dimensional (2D) layers precede the three-dimensional (3D) nucleation in the SK mode at x=1.0 depnds on the lattice misfit.

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