• 디지털융복합연구
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• 제17권3호
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• pp.55-61
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• 2019

본 연구는 올바른 창의 인성 함양을 위한 동요지도를 멀티미디어 자료로 개발하여 효과를 살펴보고자 했다. 이를 위해, 초등학생을 대상으로 인성 함양에 적합한 동요를 선별하고, 애니메이션이나 다큐멘터리, 합창이나 무용 공연, 인터뷰 등 다양한 영상 자료를 포함한 멀티미디어를 제작하고, 제작된 자료를 초등학교에서 동요방송으로 운영하였다. 무엇보다, 교사들이 학생들에게 동요를 쉽게 지도할 수 있도록 교수 학습안과 활동지를 프로그램으로 고안하여 재량활동 시간을 통해 '창의적인 교수 학습 활동안'으로 프로그램이 진행되었고, 학급 홈페이지를 통해 가정에서도 연계할 수 있도록 제시하였다. 그 결과, 동요방송을 통해 초등학생의 인성변화가 긍정적으로 나타났고, 초등학교 시기에 가장 강조되어야 할 창의 인성 함양을 위한 실제적인 활용방안을 통합적인 접근방법에서 논의하고자 했다.

• BMB Reports
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• 제52권4호
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• pp.265-270
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• 2019

We investigated whether SIRT1 is associated with reactive oxygen species (ROS) accumulation during CK2 downregulation-mediated senescence. SIRT1 overexpression suppressed ROS accumulation, reduced transcription of FoxO3a target genes, and nuclear export and acetylation of FoxO3a, which were induced by CK2 downregulation in HCT116 and MCF-7 cells. Conversely, overexpression of a dominant-negative mutant SIRT1 (H363Y) counteracted decreased ROS levels, increased transcriptional activity of FoxO3a, and increased nuclear import and decreased acetylation of FoxO3a, which were induced by CK2 upregulation. CK2 downregulation destabilized SIRT1 protein via an ubiquitin-proteasome pathway in human cells, whereas CK2 overexpression reduced ubiquitination of SIRT1. Finally, the SIRT1 activator resveratrol attenuated the accumulation of ROS and lipofuscin as well as lifespan shortening, and reduced expression of the DAF-16 target gene sod-3, which were induced by CK2 downregulation in nematodes. Altogether, this study demonstrates that inactivation of the SIRT1-FoxO3a axis, at least in part, is involved in ROS generation during CK2 downregulation-mediated cellular senescence and nematode aging.

• 한국의류학회지
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• 제47권3호
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• pp.475-491
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• 2023

New product development (NPD) is crucial for fashion brands as they are required to constantly innovate in product design and technology to remain competitive in the global fashion market. In this study, we investigated the co-creative new fashion product development (NFPD) process to understand its structural characteristics and examined the components of this business model through case studies. Fashion companies frequently collaborate with consumers to create unique and innovative fashion items that both satisfy consumer demand and expand their economic potential. Base on case studied involving consumer participation in NFPD, our study analyzed the structural characteristics of the co-creative NFPD process. Consequently, our investigation identified five key factors of the co-creative NFPD business model: co-value, co-creator, co-activity, co-platform, and co-partner. The co-creation approach established in this study will help advance research on new fashion strategies and provide foundational information for Korean fashion companies that are facing an increasingly competitive global market, thus making a significant contribution to the literature.

• 한국가구학회지
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• 제25권4호
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• pp.239-249
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• 2014

Color is an important subject of interest for cognitive developmental stages of children and it also correlate to emotional and physical development. Children can acquire concept of color by 'play'. Color play can be experienced to children through diversity activity and theses activities contain creative craft art activity. The color-paly with art activity for kids can be called 'kids color-design play'. Recently, indoor playgrounds are rapidly grow-up because parent's concern degree that about play activity get higher. The indoor playground being enlargement and it contains various paly contents. Color-design play is also enacted animatedly in kids indoor playground. The great part of color-design plays are enacted through program that needs teaching. On the other hand, color-design play facility that children can play spontaneously is not composed sufficiently. Therefore this study aim at design proposal of 'Kids color-design playground apparatus' in indoor playground.

• 한국의류학회지
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• 제43권6호
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• pp.808-824
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• 2019

This study analyzes the values of vintage in Korean fashion prosumer's activities and elevates the values as one characteristic of Korean modern fashion. The methodology included literary and empirical studies as well as prosumer and modern Korean vintage fashion literary studies. In-depth interviews were done to analyze the values of vintage in fashion prosumer's activities. The values of vintage fashion for Millennials are creative activities based on public interest, expanded reproducing through sharing daily looks and self-expression through the scarcity of vintage clothing. Prosumer characteristics are self-satisfaction and sharing. Fashion prosumer's vintage trends are new-tro, communication, cultural complex, and sharing of daily life. The formativeness in fashion prosumer's activities are heritage, text, activity and image. The meanings are creation, communication, experience and sharing. Fashion prosumers are developing the new genre of 'vintage fashion activity'; in addition, values towards vintage fashion activity are also drawing international interest.

• 한국임상수의학회지
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• 제15권1호
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• pp.41-45
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• 1998

This study was performed to investigate the serum creative kinase(CK) activity and CK isoenzyme in Jindo dog. Serum CK activity and CK-isoenzyme were analyzed in 53 Jindo dogs of both sexes. The mean value and normal range of serum CK activity were 24.1 lu/$\ell$ and 7-91 lu/$\ell$, respectively, in 29 female dogs, 24.8 lu/$\ell$ and 8-89 lu/$\ell$ in 24 male dogs. The CK activity of the Puppy showed a tendency to be higher than that of the adult. There was no significance between Puppy and adult. Three isoenzymes (CK-MM, CK- BB, and CK-MB) were recognized in serum. The mean percentages of female and male were as follows: 48.31fp and 48.1% for CK-MM, 35.49) and 33.61fp for CK-BB, and 8.2% and 10.1% for CK-MB in the puppy and 46.21% and 46.1 % for CK-MM, 36.3% and 37.6% for CK-BB and 10.5% and 9.5% for CK-MB in the adult.

• 한국콘텐츠학회논문지
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• 제13권4호
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• pp.469-480
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• 2013

본 연구의 목적은 일반 동극활동, 증강현실기술과 로봇을 적용한 동극활동, 증강현실기술과 로봇을 적용한 창의적 동극활동을 실시하고 유아의 사용자 경험 반응을 살펴보고자 하였다. 이를 위해 만 5세 유아 20명을 대상으로 6주 동안 3편의 동화를 감상한 후, 각각 동화에 대한 세 가지 동극활동을 차례대로 진행하였다. 이후 모든 동극활동 프로그램에 참여한 유아들을 대상으로 인터뷰를 실시하였다. 연구 결과는 첫째, 유아가 가장 흥미로워했던 동극활동은 증강현실기술과 로봇을 적용한 창의적 동극활동인 반면, 가장 흥미 없었던 동극활동은 일반 동극활동이었다. 둘째, 유아가 가장 쉽다고 답한 동극활동은 증강현실기술과 로봇을 적용한 동극활동인 반면, 가장 어렵게 인식했던 동극활동은 증강현실기술과 로봇을 적용한 창의적 동극활동이라고 하였다. 셋째, 증강현실기술과 로봇을 적용한 동극활동에 대해 모든 유아가 기술은 어렵지 않다고 답변하였고, 증강현실기술의 효과, 로봇의 역할 모두 정확하게 인식하여 답변하였다. 본 연구의 결과는 유아를 위한 디지털 리터러시 교육의 성격과 방향에 대한 적극적이고 체계적인 연구의 필요성을 시사한다.

• 한국엔터테인먼트산업학회논문지
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• 제15권1호
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• pp.117-129
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• 2021

최근 유아교육의 흐름은 각 교과와 영역의 융합을 통한 학습자 중심의 통합적인 경험으로 학습의 질을 높일 수 있는 교육활동을 모색하는 데 중점을 두고 있다. 예비유아교사의 음악극 활동은 예술 교과 간의 통합교육으로 예술의 역할과 가치를 이해할 수 있고 나아가 인성과 창의성 계발에 직접적인 영향을 미치기도 하며 다양한 학습에 직접적인 흥미를 유발시키는 동기가 되기도 한다. 또한 유아교육현장에서 음악극을 기획하고 실행, 지도할 수 있는 능력을 향상시킬 수 있는 활동이다. 피아노 앙상블을 활용한 창의적인 음악극 지도 방안의 개발은 교원양성과정의 통합교육활동에 대한 기초연구를 지원하고 음악극 활동이 활성화할 수 있을 것으로 기대된다. 연구 결과 및 제안은 다음과 같다. 첫째, 음악극 활동은 예비유아교사의 협동학습과 창의적인 계획에 의하여 관람 대상에 맞게 체계적이고 단계적으로 실행되도록 한다. 둘째, 음악극의 등장인물의 특징을 이해하고 효율적인 출연진의 역할을 분담하는 것은 예비유아교사 음악극 활동의 접근도를 높이고 활성화의 효과를 가져올 수 있다. 셋째, 음악극 활동 중 음악 만들기는 예비유아교사의 음악적 이해력과 수준에 맞게 창작, 편곡하여 실행할 수 있다. 넷째, 교육과정 중 단기간에 효율적인 방법으로 예비유아교사들이 실행한 통합적인 경험과 평가를 통해서 나온 음악극에 대한 교수방법 및 활동자료, 기록들이 교육현장에서 유아음악극을 지도하는데 참고자료가 되도록 한다.

• 한국IT서비스학회지
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• 제10권3호
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• pp.21-30
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• 2011

Expectation for improvement of creativity and problem-solving capability has increased the creative robotics classes in the form of after-school activity in more than half of total elementary schools. While Ministry of Education, Science and Technology has promoted 'Green IT Guidelines' as a part of 'Eco-friendly Green School Development Project', the Green issues have not been considered enough in those creative robotics classes. In this paper, we would like to address the Green issues, especially in the r-Learning services based on UCR (User Created Robots). First, trend of green IT education, r-Learning services and UCR are reviewed. And the current status of eco-related operations and teachers' perception in the robotics classes of elementary schools is investigated. Examples of Green UCR are also searched and green programs based on the three kinds of UCR, UC-TR, UC-AR, UC-CR, are explored. Finally, we propose action plans to promote the UCR-based r-Learning service reflecting green issues.

• Journal of Microbiology and Biotechnology
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• 제25권6호
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• pp.759-764
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• 2015

Antimicrobial peptides (AMPs) are one of the critical components in host innate immune responses to imbalanced and invading microbial pathogens. Although the antimicrobial activity and mechanism of action have been thoroughly investigated for decades, the exact biological properties of AMPs are still elusive. Most AMPs generally exert the antimicrobial effect by targeting the microbial membrane, such as barrel stave, toroidal, and carpet mechanisms. Thus, the mode of action in model membranes and the discrimination of AMPs to discrepant lipid compositions between mammalian cells and microbial pathogens (cell selectivity) have been studied intensively. However, the latest reports suggest that not only AMPs recently isolated but also well-known membrane-disruptive AMPs play a role in intracellular killing, such as apoptosis induction. In this mini-review, we will review some representative AMPs and their antimicrobial mechanisms and provide new insights into the dual mechanism of AMPs.