• Title/Summary/Keyword: counter-transport

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EFFECT OF INSULIN ADMINISTRATION ON THE COLLAGEN BIOSYNTHESIS IN INCISOR PULP AND GINGIVA OF RAT (Insulin 투여가 백서치수 및 치은의 Collagen 생합성에 미치는 영향)

  • Kim, Gwan-Shik
    • The Journal of the Korean dental association
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    • v.19 no.6 s.145
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    • pp.529-533
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    • 1981
  • The effect of insulin on the collagen metabolism in dental pulp and gingiva was studied using Sprague-Dawley rat and ³H-proline was injected intraperitoneally and then sacrificed according to predetermined schedule. Lower incisor pulp and gingiva were removed immediatedly and hydrolysed with acid. After digestion, proline and hydroxyproline were separated and analysed quantitatively employing thin-layer chromatography and radioactivity of each amino acid was counted by liquid scintillation counter. The label incorporated into lower incisor pulp and gingiva and radioactivity of ³H-hydroxyproline were increased in insulin administered group. And disappearance rate of ³H-hydroxyproline was decreased. Those results indicated that amino acid, I.e. proline transport and collagen biosynthesis were increased in dental pulp and gingiva by insulin administration.

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A Numerical study on current density and temperature distributions of IT-SOFC (IT-SOFC의 전류밀도 및 온도분포에 관한 수치해석 연구)

  • Sohn, Sang-Ho;Lee, Kyu-Jin;Nam, Jin-Hyun;Kim, Charn-Jung
    • Proceedings of the KSME Conference
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    • 2008.11b
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    • pp.3067-3072
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    • 2008
  • A two-dimensional model for anode-supported IT-SOFCs is proposed in order to accurately consider the heat and mass transport processes with a fully-developed axial velocity profile in channel flow. A comprehensive micro model is employed to describe the electrochemical reaction in anode and cathode of SOFCs. This paper investigates the effects of operational parameters (inlet temperature, the amount of flow rate, and air flow rate) including flow configurations (co-flow and counter-flow) on the current density and temperature distributions in the IT-SOFCs.

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Self-Diffusion of THO within Tactic Poly(2-hydroxyethyl methacrylate) Membranes

  • Kim, Hye-Kyeong;Jhon, Mu-Shik
    • Bulletin of the Korean Chemical Society
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    • v.4 no.3
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    • pp.128-132
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    • 1983
  • The self-diffusion experiment of water was performed across two series of tactic poly(2-hydroxyethyl methacrylate), P(HEMA) membranes prepared by crosslinking with various amount of hexamethylene diisocyanate (HMDIC). The tagging material was tritium hydroxide (THO) and the efflux of THO was counted on a Liquid Scintillation Counter. The transport data of THO show that the permeability decreases as the amount of HMDIC increased from 2.5 to 10 mole % and the self-diffusions coefficient shows a parallel trend with it. The diffusivity data was discussed in terms of the change of water structural orderliness within membranes. Using the relation between viscosities and diffusivities derived from Eyring's absolute rate theory, the corresponding viscosities of water within two series of tactic P(HEMA) membranes were obtained. From this, it is seen that the viscosity of water within tactic P(HEMA) membranes may have the same values with those of supercooling water whose temperature ranges from -28 to -$36^{\circ}C.$.

A case study on the conditions of direct transport for the preferential tariff treatment through Korea-EU FTA(Free Trade Agrement) (한.EU FTA하에서 협정관세적용을 위한 직접운송 요건의 충족여부에 관한 사례연구)

  • Han, Sang-Hyun
    • International Commerce and Information Review
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    • v.15 no.2
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    • pp.207-232
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    • 2013
  • FTA(Free Trade Agreement) of South Korea and European Union(EU) took effect from July 1, 2011. Korea signed a contract FTA with the European Union by first among Asian country, and Korea EU FTA is evaluated that it is wide, comprehensive and high level FTA. Therefore, Korea EU FTA will become FTA that dimension is high, and FTA fermentation with the European Union may activate the Korean economy through extension of export. By the way, in Korea EU FTA, the stipulations on import and export clearance system is different compared with other FTA. Therefore, exporter and importers should compare thoroughly on essential factor of origin standard and preferential tariff which is set in FTA Agreement. In this study, I analyzed 'conditions of direct transport' that is prescribed in article 13 of Korea EU FTA. Particular, I analyzed recently example of appeal for review that decision is made in the Korea Customs Service(KCS). Laying stress on counter measure of business, conclusion in this study is as following. First, companies must understand correctly a single consignment and a single transport document under Korea EU FTA. Second, companies must not analyze wrong 'conditions of direct transport'. Third, when simplicity transshipment or temporary custody is consisted, companies must secure documentary evidence as soon as possible. Fourth, in case goods pass third country, companies must understand uprightly 'a single consignment'. Finally, companies should keep in mind to truth that European Union and EFTA are different FTA.

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Mechanism of Catecholamine Secretion Evoked by Lithium from the Isolated Perfused Rat Adrenal Gland (흰쥐 적출관류부신에서 리튬에 의한 카테콜아민 분비작용의 기전)

  • Lim, Dong-Yoon;Kim, Cheol;Oh, Hyeong-Geun
    • The Korean Journal of Pharmacology
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    • v.32 no.3
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    • pp.357-371
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    • 1996
  • Lithium (Li) is known to be used not only during acute manic psychosis but also acute depressive phase in manic-depression. In the present study, it was attempted to investigate the effect of lithium on catecholamine (CA) secretion from the isolated perfused rat adrenal gland and to clarify the mechanism of its action. Replacement of $Na^+$ (118.4 mM) by lithium in the normal Krebs-bicarbonate solution used to perfuse the gland produced gradually an increased response in the spontaneous catecholamine release, which was peaked at $30{\sim}60$ min after its perfusion. Li-Krebs solution was perfused into an adrenal vein for 2 hours in every experiments. Li-Krebs-evoked CA secretory responses were depressed significantly under loading with $Ca^{++}-free$ medium. This CA secretion evoked by lithium loading was also reduced markedly by the pretreatment with nicardipine ($10^{-6}$ M), TMB-8 ($10^{-5}$ M) and chlorisondamine ($10^{-6}$ M) for 20 min, respectively, while was not affected by preloading with a pirenzepine ($2{\times}10^{-6}$ M)-containing Krebs. $Na^+$ pump inhibition by pretreatment with ouabain ($10^{-4}$ M) for 20 min did make the marked depression in Li-evoked CA secretory responses. Moreover, Li-evoked CA release was also diminished markedly by preloading with tetrodotoxin ($5{\times}10^{-7}$ M)-contaming Krebs for 20 min. All these experimental results taken together suggest that lithium enhances CA secretion in a $Ca^{++}$-dependent fashion by its accumulation in the adrenomedullary chromaffin cells of the rat, and that this secretory effect may be meidated by a dual mechanism: (i) chromaffin cell depolarization and subsequent opening of voltage-sensitive $Ca^{++}$ channels and (ii) activation of a $[Li]_i-[Ca]_0$ counter-transport system.

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Review on Prior Evaluation for Terrorism Risk of High-rise Buildings (초고층건축물의 테러 위험도 사전평가에 관한 연구)

  • Seong, Bin;Lee, Yoon-Ho
    • Korean Security Journal
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    • no.36
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    • pp.293-316
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    • 2013
  • Today's high-rise buildings are increasing concern about the safety and evacuation of people related to the fire and threat from outside. Terrorism breaking out in high-rise buildings, a symbol of the national economy results in a number of casualties, economic loss, social fear and damage to national status. That's why high-rise building has also emerged as a target of major terrorist attacks, compared to other types of buildings. We have 54 high-rise buildings in 15 regions over the country. The Ministry of Land, Infrastructure and Transport and Seoul Metropolitan Government have offered the guidelines to prevent terrorist attacks toward high-rise buildings. Since the 9/11 terrorist attacks, the U.S. Federal Emergency Management Agency (FEMA) has developed and taken advantage of the Risk Management Manual Series. According to this manual, pre-assessment is conducted for the prevention of terrorism and particularly in FEMA 455, risk of the surrounding areas, vulnerability, possibility from terrorist attacks are checked. After the check, experts classify the risk of terrorist attacks toward the high-rise buildings and according to the risk classification, architects, security experts and structure engineers can carry out terrorism prevention program for high-rise buildings. The U.K. NaCTSO has also offered the terrorism prevention guidelines. Therefore, the Ministry of Land, Infrastructure and Transport and Seoul Metropolitan Government should make more concrete guidelines for high-rise buildings such as what U.S. FEMA and U.K. NaCTSO implement, including prior evaluation technique for terrorism risk.

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Neutron Dose Measurements Using TLDs in a 252Cf Neutron Field (252Cf 중성자장에서 열형광선량계(TLD)를 이용한 중성자 방사선량 측정)

  • Chang, Insu;Kim, Sang In;Lee, Jung Il;Kim, Jang Lyurl;Kim, Bong Hwan
    • Journal of Radiation Protection and Research
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    • v.38 no.1
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    • pp.37-43
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    • 2013
  • In case of neutron dose measurement using TLDs (thermo-luminescence dosimeters), because the neutron energy dependence of the TLD is very high, the calibration of the energy response according to the characteristics of the neutron spectrum of workplace is required. In the present study, the ambient dose equivalent rates inside and around the Long-Counter (neutron detector) with narrow and complex inside in the neutron field of $^{252}Cf$ were evaluated. The calibration factors to account for the neutron energy dependence of TLDs were established for both the bare and $D_2O$ modulated $^{252}Cf$ neutron beams, respectively. The values of the TLD's measurement were compared with the computational results of the MCNPX (Monte Carlo N-Particles transport code). When using the two calibration factors of the TLD than a single calibration factor, the measured and the calculated values at the point of verification outside and inside the Long-Counter were in more good agreement. This results show that TLD should be calibrated in the reference neutron field similar to workplace situation.

Time Series Observations of Atmospheric Radon Concentration in Seoul, Korea for an Analysis of Long-Range Transportation of Air Pollutants in the North-East Asia (동북아 오염물질 장거리이동 분석을 위한 서울시 대기 중 라돈농도의 시계열적 특성에 관한 연구)

  • Kim, Yoon-Shin;Lee, Cheol-Min;Kim, Ki-Youn;Jeon, Hyung-Jin;Kim, Jong-Cheol;Iida, Takao
    • Journal of Environmental Health Sciences
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    • v.33 no.4
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    • pp.283-292
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    • 2007
  • Atmospheric concentrations of radon had been continuously observed in Seoul, Korea since December 1999, as a tracer for long-range transport of air pollutants from China continent to Korea. In order to study radon as a tracer of long-range transport, it is important to know information about the atmospheric distribution and variation of radon concentration and its time variation. Atmospheric radon concentration are measured with electrostatic radon monitor(ERM) at Hanyang University located in Eastern area of Seoul. Air sample is taken into a vessel of ERM, and alpha particles emitted by radon daughters $Po^{218}$ are detected with ZnS(Ag) scintillation counter. Hourly mean concentrations and hourly alpha counts are recorded automatically. The major results obtained from time series observation of atmospheric radon were as follows : (1) The mean of airborne radon concentration in Seoul was found to be $7.62{\pm}4.11\;Bq/m^3$ during December $1999{\sim}January$ 2002. (2) The hourly variation of radon concentrations showed the highest in 8:00AM ($8.66{\pm}4.22\;Bq/m^3$) and the lowest in 3:00AM ($6.62{\pm}3.70\;Bq/m^3$) and 5:00AM ($6.62{\pm}3.39\;Bq/m^3$). (3) the seasonal variation of radon concentrations showed higher during winter-to-fall and lower during summer-to-spring. (4) Correlation between airborne radon concentration and the meteorological factors were -0.21 for temperature, 0.09 for humidity, -0.20 for wind speed, and 0.04 for pressure. (5) The mean difference of airborne radon concentration between Asian dust ($5.36{\pm}1.28\;Bq/m^3$) and non-Asian dust ($4.95{\pm}1.49\;Bq/m^3$) phenomenon was significant (p=0.08). We could identify time series distribution of radon concentration related meteorological factors. In addition, radon can be considered a good natural tracer of vertical dispersion and long-range transport.

Comparative Study on the Transport Characteristics of Canalicular Liver Plasma Membrane Vesicles Prepared by Two Different Methods (제조 방법에 따른 간 모세담관막 소포계의 수송 특성 비교)

  • Song, Im-Sook;Chung, Suk-Jae;Shim, Chang-Koo
    • Journal of Pharmaceutical Investigation
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    • v.29 no.1
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    • pp.13-19
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    • 1999
  • Canalicular liver plasma membrane vesicles (cLPM) were prepared according to two different methods (Inoue method and Meier method), and were evaluated for their protein yield, enzyme activity and transport characteristics. No difference was found between the methods in the protein yield (i.e., $0.14{\pm}0.031$ and $0.15{\pm}0.050$ mglg liver for Inoue method and Meier method, respectively). The activity of alkaline phosphatase, a marker enzyme of canalicular membrane, was significantly (P<0.05) higher in the vesicles of Meier method $(3.52{\pm}0.91\;mmol/mg/hr)$than in the vesicles of Inoue method ($2.28{\pm}0.94$ mmol/mg/hr) indicating that more purified cLPM were obtained from Meier method compared with Inoue method. ATP-dependent vesicular uptake of taurocholate and tributylmethylammonium (TBuMA) was observed for vesicles of both methods, and the kinetic parameters responsible for the transport were similar between the vesicles of both methods (for example, $V_{max}:$ 9.72 nmol/mg protein/30sec and $K_m:$ 0.63 mM for Inoue method; $V_{max}:$ 10.1 nmol/mg protein/30sec and $K_m:$ 0.70 mM for Meier method). A pH gradient dependent counter transport of TBuMA was also observed for both vesicles with similar kinetic characteristics. Either the uptake of taurocholate in the absence of ATP or that of TBuMA in the absence of pH gradient, which may represent passive diffusion of respective compound into the vesicles, was more rapid for the vesicles of Meier method than for the vesicles of Inoue method. For example, passive diffusion rate constants $(K_d)$ for TBuMA uptake into the vesicles were 0.00030 and 0.00052\;{\mu}l/mg$ protein/min for the vesicles of Inoue method and Meier method, respectively. It may indicate that more leaky vesicles are obtained form the Meier method compared with the Inoue method. These aspects together with the time necessary to prepare the vesicles (i.e., 8 hr for Inoue method and 23 hr for Meier method) should be considered before selecting an appropriate method for the preparation of cLPM.

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An Efficient Lighting Control System Design for LSDM Control on AVR (AVR 기반의 LSDM 제어를 위한 효율적인 점등제어 시스템 설계)

  • Hong, Sung-Il;Lin, Chi-Ho
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.11 no.5
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    • pp.116-124
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    • 2012
  • In this paper, we propose an efficient lighting control system design for AVR based LSDM control. This paper, an efficient lighting control system design for LSDM control be design divided as the signal control part for I/O data bus and the timer/counter part for clock signal control according to operating conditions. LSDM control logic be optimization to PORTx and DDRx register by specifying the logical value of each bit for effective control signal processing. And, the LSDM control signal by lighting control program execution of ATmega128 be designed to be LSDM lighting control by control logic operating. In this paper, a proposed lighting control system were measured to power loss rate to proved the power loss reduction about lighting status of LSDM control logic by download the lighting control program to system through serial from host PC. As a measurement result, a proposed lighting control system than the existing lighting control system were proved to be effective to the overall power consumption reduction.